Abstract:
OBJECTIVE:We have previously shown a decrease in the overall stillbirth rate at our institution in women receiving the seasonal influenza vaccine during pregnancy. The goal of this study was to ascertain factors associated with this decrease. STUDY DESIGN:This was a retrospective cohort study examining the stillbirth rate, etiology, autopsy findings, and placental pathology in pregnant women receiving the seasonal trivalent inactive influenza vaccine during five influenza seasons between 2003 and 2008. All stillbirths at our institution are investigated by a committee and an etiology is assigned. Autopsy is offered to all patients and placental evaluation is performed routinely. RESULTS:During the study period, 8,690 pregnant women received the seasonal influenza vaccine antepartum and delivered at our institution. Thirty of these births were complicated by stillbirth as compared with 436 stillbirths in the 76,153 women not vaccinated (0.35 vs. 0.57%, p = 0.006). No association was identified between assigned causes of stillbirth when comparing vaccinated and nonvaccinated women. CONCLUSION:No specific etiology commonly associated with stillbirth was identified to have been affected by maternal antepartum influenza vaccination.
journal_name
Am J Perinatoljournal_title
American journal of perinatologyauthors
Wortman AC,Casey BM,McIntire DD,Sheffield JSdoi
10.1055/s-0034-1544046subject
Has Abstractpub_date
2015-05-01 00:00:00pages
571-6issue
6eissn
0735-1631issn
1098-8785journal_volume
32pub_type
杂志文章abstract::We measured Thrombopoietin (Tpo) levels in thrombocytopenic term and preterm babies with infection to investigate the relationship between thrombopietin levels and platelet counts. Sixteen preterm (27-34 weeks' gestational age) and 5 term neonates (38-41 weeks' gestational age) with the diagnosis of neonatal infection...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2001-16990
更新日期:2001-08-01 00:00:00
abstract::I developed a single equation that simulated previously published growth charts for very low-birth-weight infants, using birth weight as the only variable. The intent of this study was to validate the equation using infants admitted to our neonatal intensive care unit (NICU) and to determine if this equation could be ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993914
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to examine the hypothesis that prolonged rupture of membranes (PROM) is associated with increased cord blood erythropoietin (EPO) concentrations, proportional to the duration of ruptured membranes. STUDY DESIGN:This study is a prospective, cross-sectional, observational (nonintervent...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1384643
更新日期:2015-03-01 00:00:00
abstract::We report about two newborns with sudden onset of inability of mechanical ventilation due to transient chest wall rigidity after fentanyl i.v. bolus of 2 and 4 microg/kg, respectively, resulting in severe hypoxemia and secondary bradycardia. A third case developed a rigidity of the tongue after fentanyl bolus, which c...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2000-7289
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to describe the experience with a protocol of therapeutic hypothermia (TH) in southern Brazil. STUDY DESIGN:Newborns with gestational age > 35 weeks with evidence of perinatal asphyxia plus moderate or severe encephalopathy were recruited between March 2011 and November 2017. Whole-body hypo...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1692388
更新日期:2020-07-01 00:00:00
abstract::Introduction Bronchopulmonary dysplasia (BPD) is a frequent, long-term complication in very low-birth-weight (VLBW) newborns. Its etiology is multifactorial and the oxidative stress is one of its main causes. Breast milk (BM) reduces oxidative stress and provides antioxidant protection, therefore, BM may have a protec...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1586503
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes. STUDY DESIGN:We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. Analysis was limited to women with BMI recorded at <24 weeks for both ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1670634
更新日期:2019-04-01 00:00:00
abstract::We studied the effect of antenatal corticosteroids on the incidence of respiratory disorders in singleton neonates born between 34 and 36 weeks of gestation. Retrospective analysis was conducted of the incidence of respiratory distress syndrome (RDS) and other respiratory disorders (need for mechanical ventilation, co...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-1022470
更新日期:2008-02-01 00:00:00
abstract::The objective of this study was to evaluate the effect of prophylactic antibiotic treatment on prenatal and neonatal outcome after preterm premature rupture of the membranes (P-PROM). The study population consisted of 172 pregnant women admitted to the Rabin Medical Center in Israel with P-PROM at 23-34 gestational we...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2000-10004
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:The objective of this article is to evaluate the implementation and acceptability of a universal cervical length (CL) screening program for prediction and prevention of preterm birth (PTB). STUDY DESIGN:We performed a prospective observational study to evaluate the implementation and acceptability of a unive...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1371710
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:Fetal tachyarrhythmias complicate 0.5% of pregnancies, with high morbidity and mortality. We hypothesized that maternal factors may predispose to fetal supraventricular tachycardia (SVT). STUDY DESIGN:We reviewed medical records of all 124 mothers who presented to the Vanderbilt Fetal Cardiology Clinic from ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1552942
更新日期:2015-11-01 00:00:00
abstract::External cephalic version should be followed by fetal and maternal surveillance until delivery. To shorten this period of surveillance, a protocol of version at term, followed by immediate induction of labor, was adopted. The aim of the present study was to evaluate the effect of this protocol on the subsequent mode o...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994508
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:To develop a model to predict cesarean-associated red blood cell transfusion. STUDY DESIGN:Secondary analysis of all cesarean deliveries in the Maternal-Fetal Medicine Units Network Cesarean Registry. Using a split-sample technique, the derivation group was used to identify associated factors and build predi...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0039-1678604
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To determine the risk of spontaneous preterm delivery (SPTD) associated with transvaginal cervical length (TVCL) in an unselected cohort. STUDY DESIGN:This is a retrospective study of serial TVCLs in unselected twin gestations. Receiver operator curves for SPTD were constructed from TVCLs at 18, 20, 22, and ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0038-1676484
更新日期:2019-10-01 00:00:00
abstract::Four hundred sixty-four fetuses underwent real time ultrasound examination within 72 hours before birth to evaluate other factors than the weight formula itself that might influence the accuracy of ultrasound weight estimation. The results indicated that fetal sex had no effect on weight estimation accuracy, but that ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999866
更新日期:1986-07-01 00:00:00
abstract::We sought to evaluate the effectiveness of daily oral micronized progesterone (MP) in preventing recurrent spontaneous preterm birth (RSPB) and whether MP increases maternal serum progesterone. We performed a pilot, single-center, randomized, double-blind, placebo-controlled trial in women with a prior preterm birth a...
journal_title:American journal of perinatology
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0031-1274509
更新日期:2011-05-01 00:00:00
abstract::The purpose of this study is to identify obstetrical factors associated with adverse neurological outcome in < or =1000-g infants. In a 1-year (1992-1993) observational study, the NICHD MFMU Network collected obstetrical risk factors for 486 infants who weighed < or =1000 g at birth and who survived > 2 days. Infants'...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-993833
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to evaluate the impact of multiple pregnancies, maternal obesity, and preeclampsia on the effect of antenatal steroids on neonatal respiratory distress syndrome (RDS). STUDY DESIGN:The retrospective cohort study was performed in a level III maternity ward. Population was composed of ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1548537
更新日期:2015-09-01 00:00:00
abstract::Magnesium sulfate is used for seizure prophylaxis in patients with preeclampsia. It also has significant effects on calcium metabolism and could, therefore, alter the pressor response to calcium-dependent vasoconstrictors. The present in vivo rat study examined the effect of magnesium sulfate to alter the pressor resp...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999292
更新日期:1992-09-01 00:00:00
abstract::We report the sixth pregnancy and the first occurrence of twins after liver transplantation, and the second time cyclosporine was used in pregnancy for that indication. The pregnancy was interrupted at 33 weeks, menstrual age, for exacerbation of chronic graft rejection and intrauterine growth retardation of both twin...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999362
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:The aim of the article is to review the effectiveness of neonatal noninvasive high-frequency ventilation (NIHFV) in preventing endotracheal mechanical ventilation. STUDY DESIGN:Retrospective case series including all 79 instances of NIHFV use at four participating centers between July 2010 and September 2012...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0034-1381317
更新日期:2015-02-01 00:00:00
abstract::The ultrastructural architecture of colostral cells of mothers of pre- and full-term infants is described. The polymorphonuclears were engaged in vivid phagocytosis of fat droplets. Similar findings were observed on the macrophages. The lymphocytes appeared normal in size and ultrastructure. A small number of eosinoph...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994162
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:Placenta previa and prior cesarean delivery are known risk factors for placenta accreta. However, other risk factors have not been identified. Our objective was to examine risk factors for accreta using data collected prospectively in a large multicenter cohort. STUDY DESIGN:Secondary analysis of women with ...
journal_title:American journal of perinatology
pub_type: 杂志文章,多中心研究
doi:10.1055/s-0033-1361833
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:This study aims to evaluate vaginal microbiota differences by bacterial vaginosis (BV), birth timing, and race, and to estimate parameters to power future vaginal microbiome studies. METHODS:Previously, vaginal swabs were collected at 21 to 25 weeks (stored at -80°C), and vaginal smears evaluated for BV (Nug...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0035-1565919
更新日期:2016-03-01 00:00:00
abstract::Intra-oral enteric duplication cysts are rare. We recently treated two infants with prenatally diagnosed large sublingual enteric duplication cysts. Antenatal aspiration of the cyst was attempted in one infant without success. Because of the potential for airway obstruction and respiratory distress at delivery, prepar...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994119
更新日期:1997-03-01 00:00:00
abstract::Seven sociodemographic and behavioral factors that may explain the increased risk of preterm deliveries among black women were examined using data from a national sample of 5823 married mothers who responded to the 1980 National Natality Survey (NNS) Questionnaire. There was a twofold increase in the rate of preterm d...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999412
更新日期:1991-09-01 00:00:00
abstract::Objective To assess the additive value of prenatal chromosomal microarray analysis (CMA) for all indications and the likelihood of detecting pathologic copy number variations (CNVs) based on specific indications. Methods A retrospective analysis was performed on amniocentesis and chorionic villi sampling results obtai...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0036-1586501
更新日期:2017-03-01 00:00:00
abstract::Interest in centralized monitoring in labor and delivery units is growing because it affords the opportunity to monitor multiple patients simultaneously. However, a long history of research on sustained attention reveals these types of monitoring tasks can be problematic. The goal of the present experiment was to exam...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-0030-1268718
更新日期:2011-06-01 00:00:00
abstract::There is increasing concern about Chlamydia trachomatis infection during pregnancy, because of reports of increased maternal, fetal, and neonatal risks. Amniotic fluid is known to possess antibacterial activity and has recently been shown to inhibit formation of chlamydial inclusions in McCoy cell culture. To further ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-999341
更新日期:1991-01-01 00:00:00
abstract::It is widely believed that prenatal care is essential if women are to have healthy pregnancies and infants. Yet many low income women do not initiate care early in their pregnancies or make sufficient visits for prenatal care. Although financial difficulties are usually considered the main reason why prenatal care is ...
journal_title:American journal of perinatology
pub_type: 杂志文章
doi:10.1055/s-2007-994556
更新日期:1994-09-01 00:00:00