3D-multi-spectral T2 mapping near metal implants.

Abstract:

PURPOSE:Due to host-mediated adverse reaction to metallic debris, there is an increasing need for noninvasive assessment of the soft tissue surrounding large joint arthroplasties. Quantitative T 2 mapping can be beneficial for tissue characterization and early diagnosis of tissue pathology but current T 2 mapping techniques lack the capability to image near metal hardware. A novel multi-spectral T 2 mapping technique is proposed to address this unmet need. METHODS:A T 2 mapping pulse sequence based on routinely implemented 3D multi-spectral imaging (3D-MSI) pulse sequences is described and demonstrated. The 3D-MSI pulse sequence is altered to acquire images at 2 echo times. Phantom and knee experiments were performed to assess the quantitative capabilities of the sequence in comparison to a commercially available T 2 mapping sequence. The technique was demonstrated for use within a clinical protocol in 2 total hip arthroplasty (THA) cases to assess T 2 variations within the periprosthetic joint space. RESULTS:The proposed multi-spectral T 2 mapping technique agreed, within experimental errors, with T 2 values derived from a commercially available clinical standard of care T 2 mapping sequence. The same level of agreement was observed in quantitative phantoms and in vivo experiments. In THA cases, the method was able to assess variations of T 2 within the synovial envelope immediately adjacent to implant interfaces. CONCLUSIONS:The proposed 3D-MSI T 2 mapping sequence was successfully demonstrated in assessing tissue T 2 variations near metal implants.

journal_name

Magn Reson Med

authors

Bhave S,Koff MF,Sivaram Kaushik S,Potter HG,Koch KM

doi

10.1002/mrm.27744

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

614-621

issue

2

eissn

0740-3194

issn

1522-2594

journal_volume

82

pub_type

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