Abstract：
:The present work developed a virtual reality (VR) counterconditioning procedure (VRCP), and investigated its efficacy in treatment of cue-induced craving in individuals with methamphetamine (METH) dependence. In study 1, thirty-one patients diagnosed with METH dependence received VRCP, while twenty-nine METH-dependent patients in waiting-list group did not. In study 2, the VRCP was computerized as a VR treatment system. Six-hundred and twelve abstinent individuals with a history of METH dependence received the computerized VRCP, while two-hundred seventy-six abstinent individuals with a history of METH dependence in waiting-list group did not. Patients with METH dependence who received VRCP showed a significantly larger decrease on the score of METH-craving and METH-liking from baseline to follow-up assessments, compared to those who did not received VRCP. Participants received VRCP showed a significantly larger decrease in HRV indexes on time domain and non-linear domain from baseline to follow-up assessments during exposure to VR cues, compared to those in waiting-list group. These findings indicate that the counterconditioning procedure under VR environment may be a useful strategy in suppressing cue-induced reactivity for patients with METH dependence.
journal_name
J Psychiatr Resjournal_title
Journal of psychiatric researchauthors
Wang YG,Liu MH,Shen ZHdoi
10.1016/j.jpsychires.2019.06.007subject
Has Abstractpub_date
2019-09-01 00:00:00pages
88-94eissn
0022-3956issn
1879-1379pii
S0022-3956(19)30411-Xjournal_volume
116pub_type
杂志文章abstract：BACKGROUND:Structural brain abnormalities have been demonstrated in subjects with BPD in prefrontal and fronto-limbic regions involved in the regulation of emotion and impulsive behavior, executive cognitive function and episodic memory. Impairment in these cognitive functions is associated with increased vulnerability...
journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
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doi：10.1016/j.jpsychires.2011.09.004
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pub_type： 临床试验,杂志文章,随机对照试验
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pub_type： 杂志文章,随机对照试验
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
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journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2004.06.004
更新日期：2005-03-01 00:00:00
