Abstract：
:In a study of regional variations in cerebral X-ray attenuation as measured by computed tomography, a relationship between bone-related beam hardening and lateralized hemispheric density differences was sought. The CT scans of 22 normal right-handed individuals were evaluated by calculating regional mean attenuation values and regional left-right differences in attenuation, comparing these to regional measurements of skull thickness. A statistically insignificant number of significant correlations was found. This is interpreted to mean that observed left-right hemispheric density differences are not due to beam-hardening through bone. It was also found that left-right differences in density persisted over the entirety of the evaluated slices, suggesting that this finding is due to inherent hemispheric structural differences.
journal_name
J Psychiatr Resjournal_title
Journal of psychiatric researchauthors
Coffman JA,Bloch Sdoi
10.1016/0022-3956(84)90017-7subject
Has Abstractpub_date
1984-01-01 00:00:00pages
269-75issue
3eissn
0022-3956issn
1879-1379pii
0022-3956(84)90017-7journal_volume
18pub_type
杂志文章abstract：OBJECTIVES:Dysfunctions in stress biology are hypothesized to contribute to anxiety disorders, and to be ameliorated during successful treatment, but limited clinical data exist to support this hypothesis. We evaluated whether increases in morning cortisol and the diurnal cortisol slope, markers of stress biology, are ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jpsychires.2017.10.011
更新日期：2018-01-01 00:00:00
abstract：:A latent class analysis paradigm for evaluating and developing diagnostic criteria was presented. How latent class analysis statistically models the conceptual structure of diagnostic systems was demonstrated. These models were then used to study the Taylor and Abrams diagnostic criteria for schizophrenia. The finding...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(82)90007-3
更新日期：1982-01-01 00:00:00
abstract：:Thirty-one elderly depressed patients were treated for seven weeks with nortriptyline with plasma levels kept between 50-180 ng/ml. Electrocardiograms were taken at the third and seventh weeks of treatment. There were significant increases in the PR interval, QTc interval, and heart rate from before and after treatmen...
journal_title：Journal of psychiatric research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0022-3956(89)90019-8
更新日期：1989-01-01 00:00:00
abstract：:Mitochondria play a critical role in energy metabolism. Genetic, postmortem brain, and brain imaging studies of bipolar disorder (BD) patients indicated that mitochondrial dysfunction might explain BD pathophysiology. Mitochondrial function can be indirectly evaluated by measuring mitochondrial DNA (mtDNA) copy number...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.11.016
更新日期：2020-11-09 00:00:00
abstract：:Genetic considerations are important in studying the pathogenesis of the psychoses. There are few reports from India, however, which have pursued a "biological marker" approach to functional illness of this type. A review of such few studies as do exist is presented to add to contemporary knowledge in the area. Recomm...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,评审
doi：10.1016/0022-3956(84)90026-8
更新日期：1984-01-01 00:00:00
abstract：:A study was undertaken of fasting and post-prandial blood levels of glucose and a number of gastrointestinal hormones in patients with anorexia nervosa. After an overnight fast their blood levels of glucose, insulin and pancreatic glucagon were significantly lower than those of age-sex matched healthy volunteers. Ther...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(85)90019-6
更新日期：1985-01-01 00:00:00
abstract：:Generalized anxiety disorder (GAD) is highly prevalent among adolescents. An early detection of individuals at risk may prevent later psychiatric condition. Genome-wide studies investigating single nucleotide polymorphisms (SNPs) concluded that a focus on epigenetic mechanisms, which mediate the impact of environmenta...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2018.03.008
更新日期：2018-07-01 00:00:00
abstract：:Few studies have tracked the long-term mental health outcomes following major disaster. We sought to document the trajectories of depressive symptoms and post-traumatic stress symptoms (PTSS) in the aftermath of the 2011 Great East Japan earthquake and tsunami. A cohort of community-dwelling older adults were followed...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.08.016
更新日期：2020-08-23 00:00:00
abstract：:Psychiatric researchers grapple with concerns that individuals with mental illness may be less likely to appreciate risks of research participation, particularly compared to people not suffering from mental illness. Therefore, empirical studies that directly compare the perspectives of such individuals are needed. In ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2019.12.010
更新日期：2020-03-01 00:00:00
abstract：:To evaluate the heritability of a personality trait, "having temper outbursts," and of associated diagnoses, we obtained histories of first degree relatives on two groups: (1) patients with temper outbursts (N = 33), and (2) diverse psychiatric patients without temper outbursts (N = 12). Family interviews were conduct...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(87)90026-4
更新日期：1987-01-01 00:00:00
abstract：:There is an emerging subjective-objective deficit paradox in schizotypy. Individuals with schizotypy report severe subjective complaints in several key functional domains commensurate with that of individuals with schizophrenia. However, objective assessments of the same domains show relatively intact performance. We ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2019.01.026
更新日期：2019-04-01 00:00:00
abstract：:Many studies have suggested that prenatal and perinatal factors increase the risk for autism spectrum disorder (ASD). However, few reports have addressed the question of their influence on the severity of the clinical presentation of children with ASD. Our objective was to determine the prenatal and perinatal factors ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.11.005
更新日期：2020-11-04 00:00:00
abstract：BACKGROUND:This nationwide population-based study investigated the risk of Parkinson's disease (PD) after zolpidem use in patients with sleep disturbance using the National Health Insurance Research Database (NHIRD) in Taiwan. MATERIAL AND METHODS:In total, 59,548 adult patients newly diagnosed with sleep disturbance ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2014.07.003
更新日期：2014-11-01 00:00:00
abstract：:While the efficacy and tolerability of electroconvulsive therapy (ECT) for depression has been well established, the acute effects of ECT on brain function remain unclear. Particularly, although cognitive dysfunction has been consistently observed after ECT, little is known about the extent and time course of ECT-indu...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2017.02.018
更新日期：2017-08-01 00:00:00
abstract：:A reported genetic association between bipolar affective disorder and DNA polymorphisms at the tyrosine hydroxylase gene is not confirmed by the present study. The combined allele frequencies in the patients, from studies published to date, are significantly different from the frequencies in the controls for the TY7/B...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(91)90022-3
更新日期：1991-01-01 00:00:00
abstract：:The personality profile of 26 adult migraine patients from a large Swedish family with migraine and 87 controls were studied by means of Cloninger's seven-factor model of Temperament and Character (TCI; Temperament and Character Inventory). For the diagnosis of migraine, a questionnaire, slightly modified to fit the c...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(96)00009-x
更新日期：1996-09-01 00:00:00
abstract：:Anorexia nervosa (AN) is a severe mental disorder accompanied by extensive metabolic and endocrine abnormalities. It has been associated with hypercortisolism using short-term measurement methods such as 24 h-urine, saliva, and blood. The aim of this study was to examine whether the proposed hypercortisolism in acutel...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2017.11.010
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:Frontolimbic dysfunction is observed in borderline personality disorder (BPD), with responses to emotional stimuli that are exaggerated in the amygdala and impaired in the anterior cingulate cortex (ACC). This pattern of altered function is consistent with animal models of stress responses and depression, whe...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2007.07.015
更新日期：2008-07-01 00:00:00
abstract：:Various studies have assessed autonomic and respiratory underpinnings of panic attacks, yet the psychophysiological functioning of panic disorder (PD) patients has rarely been examined under naturalistic conditions at times when acute attacks were not reported. We hypothesized that emotional activation in daily life c...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2015.04.027
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to assess whether individual or clusters of psychiatric symptoms can differentiate patients with psychotic major depression (PMD) from those with nonpsychotic depression (NPMD). METHOD:Data were pooled from two studies investigating patients with moderate depression. A total of 129 ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2005.07.003
更新日期：2006-02-01 00:00:00
abstract：:Primary care patients with infrequent panic attacks were found to have similar levels of disability in their social, family and vocational functioning to patients who met DSM-III-R criteria for panic disorder. Both panic subgroups had significantly more functional disability than controls. Patients with panic and infr...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(95)00006-q
更新日期：1995-03-01 00:00:00
abstract：INTRODUCTION:Even though anomalies on brain metabolites have been found in schizophrenia, researches about subjects with high risk (HR) show heterogeneous results. Thus, this meta-analysis aims to characterize the metabolic profile of HR subjects, first, compared to controls (HC) and then compared to people with schizo...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,评审
doi：10.1016/j.jpsychires.2020.03.006
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:While ketamine has been increasingly studied for treatment resistant depression (TRD), the impact of sex differences on treatment outcomes has not been well studied. The objective was to ascertain whether there were differences in response to a single administration of ketamine for TRD between men and women,...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jpsychires.2019.01.010
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Clinical and sociodemographic findings have supported that OCD is heterogeneous and composed of multiple potentially overlapping and stable symptom dimensions. Previous neuroimaging investigations have correlated different patterns of OCD dimension scores and gray matter (GM) volumes. Despite their relevant ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2012.09.002
更新日期：2012-12-01 00:00:00
abstract：:Schizophrenia (SCZ) is the result of DNA alterations and environmental factors, which together lead to differential protein expression and ultimately to the development of the illness. The diagnosis is based on clinical symptoms, and the molecular background of SCZ is not completely understood. The thalamus, whose dys...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2010.04.014
更新日期：2010-12-01 00:00:00
abstract：:Many studies have demonstrated that venlafaxine is an efficacious and safe treatment for major depressive disorder (MDD). This double-blind, placebo-controlled study was performed to evaluate the efficacy of venlafaxine extended-release (XR) (75-225 mg/day) in the prevention of relapse of depression. Patients with MDD...
journal_title：Journal of psychiatric research
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/j.jpsychires.2003.10.004
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Schizophrenia research has gained a new focus on identification and further characterization of neurocognitive deficits in the search for behavioural endophenotypes of this disorder. The objective of this study was to explore differential cortical processing during executive control in schizophrenia as asses...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2006.06.012
更新日期：2007-10-01 00:00:00
abstract：:Current antipsychotics reduce positive symptoms and reverse negative symptoms in conjunction with cognitive behavioral issues with the goal of restoring impaired occupational and social functioning. However, limited information is available on their influence on gliogenesis or their neurogenic properties in adult schi...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2017.03.008
更新日期：2017-09-01 00:00:00
abstract：:It is well-known that increased lipid peroxidation and failure of antioxidant mechanisms leads to neuronal damage in schizophrenic patients. However, this neurodegenerative mechanism has not been studied in treatment refractory schizophrenics (TRS). Therefore, the main purpose of this study was to determine neuronal d...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2006.02.010
更新日期：2007-10-01 00:00:00
abstract：OBJECTIVE:To examine the prevalence and correlates of comorbid anxiety disorders among individuals with bipolar disorders (BP) and their association with prospectively ascertained comorbidities, treatment, and psychosocial functioning. METHOD:As part of the National Epidemiologic Survey on Alcohol and Related Conditio...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2012.03.024
更新日期：2012-07-01 00:00:00
