Abstract:
:Many studies have suggested that prenatal and perinatal factors increase the risk for autism spectrum disorder (ASD). However, few reports have addressed the question of their influence on the severity of the clinical presentation of children with ASD. Our objective was to determine the prenatal and perinatal factors that are associated with the severity of autistic symptoms and intellectual and adaptive functioning deficits. Data were collected from a subset of 169 children with a confirmed diagnosis of ASD, recruited from the ELENA cohort. A risk of premature delivery was associated, with an increased risk for severe autistic symptoms and placental pathologies and birth complications were associated with an increased risk of communication adaptive deficits, in multivariate analysis. Our results highlight the importance of systematic screening for these pre/perinatal factors, especially in mothers at risk of having a child with ASD.
journal_name
J Psychiatr Resjournal_title
Journal of psychiatric researchauthors
Traver S,Geoffray MM,Mazières L,Geneviève D,Michelon C,Picot MC,Baghdadli Adoi
10.1016/j.jpsychires.2020.11.005subject
Has Abstractpub_date
2020-11-04 00:00:00eissn
0022-3956issn
1879-1379pii
S0022-3956(20)31061-Xpub_type
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journal_title:Journal of psychiatric research
pub_type: 杂志文章
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journal_title:Journal of psychiatric research
pub_type: 杂志文章
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journal_title:Journal of psychiatric research
pub_type: 杂志文章
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journal_title:Journal of psychiatric research
pub_type: 杂志文章
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journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2009.03.007
更新日期:2009-09-01 00:00:00