当前位置： SCI文献检索 > JOURNAL OF PSYCHIATRIC RESEARCH期刊下所有文献 > Adolescent anorexia nervosa: cross-sectional and follow-up frontal gray matter disturbances detected with proton magnetic resonance spectroscopy.

Adolescent anorexia nervosa: cross-sectional and follow-up frontal gray matter disturbances detected with proton magnetic resonance spectroscopy.

Abstract：

:There are very few magnetic resonance spectroscopy studies in anorexia nervosa and none of them with young adolescent patients. We studied 12 anorexia nervosa (DSM-IV) patients aged 11-17 consecutively admitted to an Eating Disorders Unit. An evaluation with laboratory data, psychopathological scales, magnetic resonance spectroscopy ((1)H MRS) and a neuropsychological battery was carried out at admission and after 7 months' follow-up and weight recovery. Psychopathological and neuropsychological and MRS examinations were also performed in 12 control subjects. In the MRS study at the frontal gray matter, the anorexic group had a significantly lower N-acetyl-aspartate (NAA) (p = .002), glutamate/glutamine (Glx) (p = .010) and myo-Inositol (mI) (p = .022) than the control group. The NAA correlated positive and significantly with triiodothyronin (Rho = .64) and the estimate level of intelligence measured with the vocabulary subtest of the WISC-R (Rho=.64). There were also positive correlations with body mass index (Rho = .47) and with attention measured with the coding subtest of the WISC-R (Rho=.51) and negative with loss of weight (Rho = -.51) but they were not statistically significant. At follow-up, there was an increase in body mass index (p=.002), triiodothyronin (p = .005), and insulin-like growth factor 1 (p = .017) and a decrease in cortisol (p = .005). In the MRS a significant increase (p = .013) in NAA was observed. The conclusion would be that NAA, Glx and mI are low in the frontal gray matter of adolescents with anorexia nervosa and specially NAA correlates with some nutritional and cognitive parameters. These alterations seem to be reversible in young patients.

journal_name

J Psychiatr Res

journal_title

Journal of psychiatric research

authors

Castro-Fornieles J,Bargalló N,Lázaro L,Andrés S,Falcon C,Plana MT,Junqué C

doi

10.1016/j.jpsychires.2006.09.013

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

952-8

issue

11

eissn

0022-3956

issn

1879-1379

pii

S0022-3956(06)00204-4

journal_volume

41

pub_type

杂志文章

相关文献

JOURNAL OF PSYCHIATRIC RESEARCH文献大全
  • Circadian periodicity, adrenal corticosteroids, and the EEG of normal man.

    abstract：:Human EEG activity in the conventional frequency range of 1-30 c/s is a well-established entity. This paper illustrates a method for utilizing a conventional EEG frequency analyser to demonstrate a considerably lower frequency, circadian (about 24-h) rhythm in the EEGs of a group of human volunteers. This periodicity ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/0022-3956(66)90020-3

    authors： Frank G,Halberg F,Harner R,Matthews J,Johnson E,Gravem H,Andrus V

    更新日期：1966-11-01 00:00:00

  • The combination of triiodothyronine (T3) and sertraline is not superior to sertraline monotherapy in the treatment of major depressive disorder.

    abstract：OBJECTIVE:To determine whether the combination of triiodothyronine (T3) plus sertraline at treatment initiation confers greater antidepressant efficacy than sertraline plus placebo in patients with major depressive disorder. METHOD:Eight-week, double blind, randomized placebo controlled clinical trial of 153 adult out...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jpsychires.2012.08.009

    authors： Garlow SJ,Dunlop BW,Ninan PT,Nemeroff CB

    更新日期：2012-11-01 00:00:00

  • Safety aspects of chronic low-frequency transcranial magnetic stimulation based on localized proton magnetic resonance spectroscopy and histology of the rat brain.

    abstract：:Because repetitive transcranial magnetic stimulation (rTMS) is capable of inducing lasting alterations of cortical excitability, it represents a promising therapeutic tool in several neuropsychiatric disorders. However, rTMS, especially when applied chronically, may cause harmful effects in the stimulated tissue. To s...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/s0022-3956(03)00017-7

    authors： Liebetanz D,Fauser S,Michaelis T,Czéh B,Watanabe T,Paulus W,Frahm J,Fuchs E

    更新日期：2003-07-01 00:00:00

  • Rosa Damascena oil improved methadone-related sexual dysfunction in females with opioid use disorder under methadone maintenance therapy - results from a double-blind, randomized, and placebo-controlled trial.

    abstract：BACKGROUND:Methadone maintenance therapy (MMT) is provided to patients with opioid use disorder (OUD). However, as with all opioids, methadone impacts negatively on sexual function. To counter this, Rosa Damascena oil (RDO) has been used successfully for opioid-dependent male patients under MMT and with methadone-relat...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jpsychires.2017.08.011

    authors： Farnia V,Tatari F,Alikhani M,Yazdchi K,Taghizadeh M,Sadeghi Bahmani D,Karbasizadeh H,Holsboer-Trachsler E,Brand S

    更新日期：2017-12-01 00:00:00

  • Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication.

    abstract：BACKGROUND:Disturbances in thyroid function have been associated with use of psychotropic drugs, including antipsychotics. Still, the thyroid function in relation to commonly prescribed antipsychotic drugs and polypharmacy is not fully known. We investigated thyroid function associated with use of antipsychotics in pat...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2018.09.014

    authors： Vedal TSJ,Steen NE,Birkeland KI,Dieset I,Reponen EJ,Laskemoen JF,Rødevand L,Melle I,Andreassen OA,Molden E,Jönsson EG

    更新日期：2018-11-01 00:00:00

  • Life history of impulsive behavior: development and validation of a new questionnaire.

    abstract：:A self-report version of the Lifetime History of Impulsive Behaviors (LHIB) interview was developed and its psychometric properties examined. Initially, forty-two personality disordered and 20 control subjects completed both the interview (I) and self-report (Q53) versions of the LHIB along with other self-report meas...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2011.11.008

    authors： Coccaro EF,Schmidt-Kaplan CA

    更新日期：2012-03-01 00:00:00

  • The effect of therapeutically induced weight gain on plasma leptin levels in patients with anorexia nervosa.

    abstract：:Previously it was shown that hyperleptinemia ensues from the therapeutically induced weight gain in patients with anorexia nervosa (AN). However, not all studies have been able to confirm this finding. To further investigate leptin secretion during weight gain in AN and potential functional implications serum leptin l...

    journal_title：Journal of psychiatric research

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0022-3956(02)00100-0

    authors： Holtkamp K,Hebebrand J,Mika C,Grzella I,Heer M,Heussen N,Herpertz-Dahlmann B

    更新日期：2003-03-01 00:00:00

  • Childhood trauma and the risk of violence in adulthood in a population with a psychotic illness.

    abstract：:There are strong links between childhood trauma and the risk of violence (Ford et al., 2007). Despite evidence that people with psychotic disorders are at a higher risk of violence than the general population (Witt et al., 2013) there have been few studies that have examined the trauma-violence link in this population...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2014.03.011

    authors： Bosqui TJ,Shannon C,Tiernan B,Beattie N,Ferguson J,Mulholland C

    更新日期：2014-07-01 00:00:00

  • HLA in psychiatric and control subjects. A comparative study of HLA antigen frequencies in schizophrenic, schizoaffective and control subjects.

    abstract：:HLA antigens were typed among 24 schizophrenic, 13 schizoaffective and 246 control subjects. Schizoaffective patients showed significantly decreased incidence of A2 compared with schizophrenic patients or controls. ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/0022-3956(85)90076-7

    authors： Adler S,Vasile RG,Yunis E,Shapiro R

    更新日期：1985-01-01 00:00:00

  • Neuromuscular and psychomotor abnormalities in patients with schizophrenia and their first-degree relatives.

    abstract：:In previous studies of schizophrenic patients, neuromuscular (histopathological and electrophysiological) and psychomotor (finger tapping) abnormalities were found. The present study was designed to investigate relationships between these abnormalities and a family history of psychosis in 14 schizophrenic patients and...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/s0022-3956(00)00031-5

    authors： Flyckt L,Wiesel FA,Borg J,Edman G,Ansved T,Sydow O,Borg K

    更新日期：2000-07-01 00:00:00

  • Altered hippocampal formation shape in first-episode depressed patients at 5-year follow-up.

    abstract：:It is generally accepted that patients with major depressive disorder have smaller hippocampus size compared to healthy people. However, it is still not known if this situation exists before the onset of the disease or is a result of the toxic mechanism created by the depression itself. The findings of the long-term f...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2012.08.022

    authors： Isıklı S,Ugurlu O,Durmusoglu E,Kizilates G,Kitis O,Ozan E,Eker C,Coburn K,Gonul AS

    更新日期：2013-01-01 00:00:00

  • Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on memory and mental processing speed in patients with major depressive disorder.

    abstract：:Patients with major depressive disorder (MDD) usually suffer from altered cognitive functions of episodic memory, working memory, mental processing speed and motor response. Diverse studies suggest that different antidepressant agents may improve cognitive functions in patients with MDD. The aim of this work is to stu...

    journal_title：Journal of psychiatric research

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jpsychires.2008.10.015

    authors： Herrera-Guzmán I,Gudayol-Ferré E,Herrera-Guzmán D,Guàrdia-Olmos J,Hinojosa-Calvo E,Herrera-Abarca JE

    更新日期：2009-06-01 00:00:00

  • The exclusion of people with psychiatric disorders from medical research.

    abstract：:People with psychiatric disorders are excluded from medical research to an unknown degree with unknown effects. We examined the prevalence of reported psychiatric exclusion criteria using a sample of 400 highly-cited randomized trials (2002-2010) across 20 common chronic disorders (6 psychiatric and 14 other medical d...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,评审

    doi：10.1016/j.jpsychires.2015.08.005

    authors： Humphreys K,Blodgett JC,Roberts LW

    更新日期：2015-11-01 00:00:00

  • Response inhibition and emotional cognition improved by atomoxetine in children and adolescents with ADHD: The ACTION randomized controlled trial.

    abstract：:Although the non-stimulant medication atomoxetine is effective for attention-deficit hyperactivity disorder (ADHD) in children and adolescents, there are still significant gaps in our knowledge about whether atomoxetine improves anxiety symptoms or cognition in children. Furthermore, while cognition has been proposed ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jpsychires.2018.03.009

    authors： Griffiths KR,Leikauf JE,Tsang TW,Clarke S,Hermens DF,Efron D,Williams LM,Kohn MR

    更新日期：2018-07-01 00:00:00

  • Subjective age and risk of incident dementia: Evidence from the National Health and Aging Trends survey.

    abstract：:The present study examines the association between subjective age and risk of incident dementia in a large longitudinal sample of older adults. Participants were adults aged 65 years and older from the National Health and Aging Trends Study (NHATS). Subjective age, covariates, and cognitive status were assessed in 201...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2018.02.008

    authors： Stephan Y,Sutin AR,Luchetti M,Terracciano A

    更新日期：2018-05-01 00:00:00

  • Frequency of bulimic behaviors and associated social maladjustment in female graduate students.

    abstract：:A questionnaire survey of 550 female medical, business and law students revealed that 12% met criteria for bulimia. The bulimic students reported significantly more social maladjustment than their non-eating disordered peers. Frequency of binging and purging was associated with the degree of social impairment, with si...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/0022-3956(86)90038-5

    authors： Herzog DB,Norman DK,Rigotti NA,Pepose M

    更新日期：1986-01-01 00:00:00

  • Relation between cerebrospinal fluid, gray matter and white matter changes in families with schizophrenia.

    abstract：BACKGROUND:Gray matter reduction and ventricular enlargement belong to the best replicated findings in schizophrenia. Brain morphologic changes were also found in non-schizophrenic family members (FM). The intention of this study was to examine whether non-psychotic first-degree relatives reveal similar morphologic cha...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2005.04.009

    authors： Schneider-Axmann T,Kamer T,Moroni M,Maric N,Tepest R,Dani I,Honer WG,Scherk H,Rietschel M,Schulze TG,Müller DJ,Cordes J,Schönell H,Steinmetz H,Gaebel W,Vogeley K,Kühn KU,Wagner M,Maier W,Träber F,Block W,Schild

    更新日期：2006-10-01 00:00:00

  • Comorbidity of borderline personality disorder and posttraumatic stress disorder in the U.S. population.

    abstract：:While placed on different axes of the DSM classification system, borderline personality disorder (BPD) and posttraumatic stress disorder (PTSD) have important relationships with trauma, and overlap between these disorders has long been recognized. The current study is the first to examine comorbidity of PTSD and BPD i...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2010.04.016

    authors： Pagura J,Stein MB,Bolton JM,Cox BJ,Grant B,Sareen J

    更新日期：2010-12-01 00:00:00

  • Cortical midline structures associated with rumination in women with PTSD.

    abstract：:Elevated rumination, characterized by repetitive, negative self-focused cognition, is common in posttraumatic stress disorder (PTSD) and has been shown to predict the onset and maintenance of the disorder. Neuroimaging research has implicated cortical midline brain structures, including the rostral anterior cingulate ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.09.001

    authors： Philippi CL,Pessin S,Reyna L,Floyd T,Bruce SE

    更新日期：2020-12-01 00:00:00

  • Sluggish cognitive tempo (SCT) in an adult outpatient sample seeking an attention-deficit/hyperactivity disorder assessment: Age of onset and assessment method impact on SCT rates.

    abstract：BACKGROUND:Sluggish cognitive tempo (SCT) is associated with-but distinct from-attention-deficit/hyperactivity disorder (ADHD). This study examined SCT rates in adult outpatients seeking an ADHD assessment, differences in rates based on ADHD status, impact of assessment method (i.e., reporting source, symptom count, an...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.09.013

    authors： Mitchell JT,Davis NO,Kollins SH,Lunsford-Avery JR

    更新日期：2020-12-01 00:00:00

  • Empathy and symptoms dimensions of patients with obsessive-compulsive disorder.

    abstract：:Patients with obsessive-compulsive disorder (OCD) often display cognitions and/or behaviors that may well reflect the existence of "hyper-attachment" to different environmental elements, including their offspring, family members, divine entities, or even inanimate objects. Based on the fact that both OCD symptoms and ...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2008.05.007

    authors： Fontenelle LF,Soares ID,Miele F,Borges MC,Prazeres AM,Rangé BP,Moll J

    更新日期：2009-01-01 00:00:00

  • Intraday weather conditions can influence self-report of depressive symptoms.

    abstract：:The weather is arguably one of the most common topics in daily conversation. However, it is also a well-known factor in psychiatric problems worldwide such as depression, where particularly elders and females are prone to the condition. Previous studies have mostly focused on the association between long-term climate/...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.02.006

    authors： Xu C,Wu W,Peng-Li D,Xu P,Sun D,Wan B

    更新日期：2020-04-01 00:00:00

  • Temporal sequencing of nicotine dependence and bipolar disorder in the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

    abstract：:Bipolar disorder (BD) and nicotine dependence (ND) often co-occur. However, the mechanisms underlying this association remain unclear. We aimed to examine, for the first time in a national and representative sample, the magnitude and direction of the temporal relationship between BD and ND; and to compare, among indiv...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2013.03.012

    authors： Martínez-Ortega JM,Goldstein BI,Gutiérrez-Rojas L,Sala R,Wang S,Blanco C

    更新日期：2013-07-01 00:00:00

  • Factor structure of the Postpartum Bonding Questionnaire: Configural invariance and measurement invariance across postpartum time periods.

    abstract：BACKGROUND:Despite the research and clinical significance of the Postpartum Bonding Questionnaire (PBQ), its psychometric properties have not been studied intensively. The goodness-of-fit of proposed factor models of the PBQ is poor. Configural and measurement invariance have never been reported. METHODS:As a secondar...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2020.11.017

    authors： Matsunaga A,Ohashi Y,Sakanashi K,Kitamura T

    更新日期：2020-11-09 00:00:00

  • Exploring the neurocognitive signature of poor set-shifting in anorexia and bulimia nervosa.

    abstract：:Poor set-shifting has been implicated as a risk marker, maintenance factor and candidate endophenotype of eating disorders (ED). This study aimed to add clarity to the cognitive profile of set-shifting by examining the trait across ED subtypes, assessing whether it is a state or trait marker, and whether it runs in fa...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2010.03.001

    authors： Roberts ME,Tchanturia K,Treasure JL

    更新日期：2010-10-01 00:00:00

  • Alterations of microRNA-124 expression in peripheral blood mononuclear cells in pre- and post-treatment patients with major depressive disorder.

    abstract：:Recently, increasing evidence has indicated that dysfunction of microRNA-124 (miR-124) might be involved in the pathophysiology and treatment of major depressive disorder (MDD) in some animal models of depression. However, the role of miR-124 in MDD patients remains unclear. The objective of this study was to investig...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2016.03.015

    authors： He S,Liu X,Jiang K,Peng D,Hong W,Fang Y,Qian Y,Yu S,Li H

    更新日期：2016-07-01 00:00:00

  • Induced abortion and anxiety, mood, and substance abuse disorders: isolating the effects of abortion in the national comorbidity survey.

    abstract：:The purpose of this study was to examine associations between abortion history and a wide range of anxiety (panic disorder, panic attacks, PTSD, Agoraphobia), mood (bipolar disorder, mania, major depression), and substance abuse disorders (alcohol and drug abuse and dependence) using a nationally representative US sam...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2008.10.009

    authors： Coleman PK,Coyle CT,Shuping M,Rue VM

    更新日期：2009-05-01 00:00:00

  • Effect of male-specific childhood trauma on telomere length.

    abstract：:Child maltreatment (CM) is a global issue with serious lifelong consequences. In fact, maltreatment during childhood might be an important risk factor for the development of psychiatric disorders. Furthermore, previous studies showed a strong relationship between telomere length (TL) and early life stress. Considering...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2018.10.012

    authors： Xavier G,Spindola LM,Ota VK,Carvalho CM,Maurya PK,Tempaku PF,Moretti PN,Mazotti DR,Sato JR,Brietzke E,Miguel EC,Grassi-Oliveira R,Mari J,Bressan RA,Gadelha A,Pan PM,Belangero SI

    更新日期：2018-12-01 00:00:00

  • Effects of doxycycline on depressive-like behavior in mice after lipopolysaccharide (LPS) administration.

    abstract：:Current evidences support inflammation, oxidative and nitrogen stress, as well as brain-derived neurotrophic factor (BDNF) signaling mechanisms as important in depression pathophysiology. Tetracycline antibiotics have anti-inflammatory and antioxidant properties. Preliminary evidence indicates that minocycline has ant...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jpsychires.2013.06.008

    authors： Mello BS,Monte AS,McIntyre RS,Soczynska JK,Custódio CS,Cordeiro RC,Chaves JH,Vasconcelos SM,Nobre HV Jr,Florenço de Sousa FC,Hyphantis TN,Carvalho AF,Macêdo DS

    更新日期：2013-10-01 00:00:00

  • Smoking status and its relationship to demographic and clinical characteristics in first episode psychosis.

    abstract：:Elevated rates of cigarette smoking are observed prior to the onset of psychosis and remain stable early in the illness. Cannabis use frequently co-occurs with cigarette smoking and is independently associated with distinct clinical outcomes. However, past research has not controlled for cannabis use in cigarette smok...

    journal_title：Journal of psychiatric research

    pub_type： 杂志文章

    doi：10.1016/j.jpsychires.2016.10.022

    authors： Grossman M,Bowie CR,Lepage M,Malla AK,Joober R,Iyer SN

    更新日期：2017-02-01 00:00:00