Abstract:
:HLA antigens were typed among 24 schizophrenic, 13 schizoaffective and 246 control subjects. Schizoaffective patients showed significantly decreased incidence of A2 compared with schizophrenic patients or controls.
journal_name
J Psychiatr Resjournal_title
Journal of psychiatric researchauthors
Adler S,Vasile RG,Yunis E,Shapiro Rdoi
10.1016/0022-3956(85)90076-7subject
Has Abstractpub_date
1985-01-01 00:00:00pages
573-8issue
4eissn
0022-3956issn
1879-1379journal_volume
19pub_type
杂志文章abstract::Genetic considerations are important in studying the pathogenesis of the psychoses. There are few reports from India, however, which have pursued a "biological marker" approach to functional illness of this type. A review of such few studies as do exist is presented to add to contemporary knowledge in the area. Recomm...
journal_title:Journal of psychiatric research
pub_type: 杂志文章,评审
doi:10.1016/0022-3956(84)90026-8
更新日期:1984-01-01 00:00:00
abstract::A self-report version of the Lifetime History of Impulsive Behaviors (LHIB) interview was developed and its psychometric properties examined. Initially, forty-two personality disordered and 20 control subjects completed both the interview (I) and self-report (Q53) versions of the LHIB along with other self-report meas...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2011.11.008
更新日期:2012-03-01 00:00:00
abstract::Cognitive-behavioral therapy (CBT) constitutes an empirically based treatment for tic disorders (TD), but much remains to be learned about its impact at the neural level. Therefore, we examined the electrophysiological correlates of CBT in TD patients, and we evaluated the utility of event-related potentials (ERP) as ...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2018.08.020
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:There is growing evidence that adolescence is a key period for neuronal maturation. Despite the high prevalence of marijuana use among adolescents and young adults in the United States and internationally, very little is known about its impact on the developing brain. Based on neuroimaging literature on norm...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2008.12.002
更新日期:2009-01-01 00:00:00
abstract::In acute psychotic schizophrenia patients we investigated if the combination of triiodothyronine (T3) plus risperidone was more effective when compared to risperidone monotherapy. Thirty-two in-patients meeting the DSM-IV-TR diagnostic criteria for schizophrenia and without thyroid disease received risperidone (flexib...
journal_title:Journal of psychiatric research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jpsychires.2015.11.007
更新日期:2016-02-01 00:00:00
abstract::Cognitive-behavioral therapy (CBT) alleviates symptoms of depression in youth with bipolar disorder (BD) and major depressive disorder (MDD). Empirical research has linked inflammatory markers to depressive symptoms and acute psychosocial stress; however, a gap remains as to whether immune response to stress may serve...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2019.10.012
更新日期:2020-01-01 00:00:00
abstract::Assuming that the experience of strong aversive tension might be an indicator of the extent of affect dysregulation within patients with borderline personality disorder (BPD), we sought to operationalize the duration and intensity of these phenomena. In addition we studied the relationship between aversive tension and...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/s0022-3956(01)00012-7
更新日期:2001-03-01 00:00:00
abstract::The anterior cingulate cortex (ACC) plays a major role in modulating executive control of attention. Here, 15 medication-nai ve patients with attention deficit/hyperactivity disorder (ADHD) and 10 carefully matched healthy controls were studied with 2D (1)H-magnetic resonance spectroscopic imaging (MRSI) of the ACC [B...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2007.06.006
更新日期:2008-06-01 00:00:00
abstract::The present study examines the association between subjective age and risk of incident dementia in a large longitudinal sample of older adults. Participants were adults aged 65 years and older from the National Health and Aging Trends Study (NHATS). Subjective age, covariates, and cognitive status were assessed in 201...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2018.02.008
更新日期:2018-05-01 00:00:00
abstract::Many studies have suggested that prenatal and perinatal factors increase the risk for autism spectrum disorder (ASD). However, few reports have addressed the question of their influence on the severity of the clinical presentation of children with ASD. Our objective was to determine the prenatal and perinatal factors ...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2020.11.005
更新日期:2020-11-04 00:00:00
abstract::Cytokines are signalling molecules, which play an important role in both immune system function and brain development and function, and subsequently mental states and behaviour. Cytokines have been implicated in eating disorders (EDs) due to their role in psychological health, body weight and appetite regulation. This...
journal_title:Journal of psychiatric research
pub_type: 杂志文章,meta分析
doi:10.1016/j.jpsychires.2018.06.002
更新日期:2018-08-01 00:00:00
abstract::Several lines of evidence indicate that alterations in intracellular calcium homeostasis with sustained elevation of free calcium ions ([Ca2+]i) might be important in the pathophysiology of Alzheimer's disease (AD). Recent studies with peripheral blood-cells have demonstrated that investigation of regulatory mechanism...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/0022-3956(96)00001-5
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:Transcutaneous electrical acupoint stimulation (TEAS) is thought to have potential to treat obsessive-compulsive disorder (OCD). OBJECTIVE:The purpose of this study was to determine whether adding TEAS to cognitive behavioral therapy (CBT) and clomipramine would improve the efficacy of these conventional tr...
journal_title:Journal of psychiatric research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jpsychires.2016.05.015
更新日期:2016-09-01 00:00:00
abstract::Hoarding behaviors are positively associated with medical morbidity, however, current prevalence estimates and types of medical conditions associated with hoarding vary. This analysis aims to quantify the medical morbidity of hoarding disorder (HD). Cross-sectional data were collected online using the Brain Health Reg...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2020.12.032
更新日期:2020-12-15 00:00:00
abstract::Current evidences support inflammation, oxidative and nitrogen stress, as well as brain-derived neurotrophic factor (BDNF) signaling mechanisms as important in depression pathophysiology. Tetracycline antibiotics have anti-inflammatory and antioxidant properties. Preliminary evidence indicates that minocycline has ant...
journal_title:Journal of psychiatric research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jpsychires.2013.06.008
更新日期:2013-10-01 00:00:00
abstract::Previous studies with 1.5 T or 3.0 T magnetic resonance imaging (MRI) have produced mixed results regarding the structural changes of the hippocampus in major depressive disorder (MDD). Subtle region-specific hippocampal tissue changes might be more sensitively detected by measuring the T2* relaxation time (T2*-RT) by...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2010.02.014
更新日期:2010-10-01 00:00:00
abstract::Deficits in sensorimotor gating, as measured with prepulse inhibition (PPI), have been considered an endophenotype of schizophrenia. However, the question remains whether these deficits are related to current symptoms. This single site study aimed to explore clinical features related to the modulation of startle refle...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2016.07.026
更新日期:2016-11-01 00:00:00
abstract::Dietary polyunsaturated fatty acids (PUFA) and inflammatory proteins associate with immune activation and have been implicated in the pathophysiology of mood disorders. We have previously reported that individuals with bipolar disorder (BPD) have decreased PUFA intake, including eicosapentaenoic acid (EPA), docosahexa...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2016.10.021
更新日期:2017-02-01 00:00:00
abstract::Glutamatergic therapies are emerging as the new path for the treatment of Major Depression Disorder. Recent reports reviewing the use of glutamate activity modulators in the treatment of resistant depression advocate the importance of understanding the alterations of the diverse components of this complex system in mo...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2013.04.007
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Structural brain abnormalities have been demonstrated in subjects with BPD in prefrontal and fronto-limbic regions involved in the regulation of emotion and impulsive behavior, executive cognitive function and episodic memory. Impairment in these cognitive functions is associated with increased vulnerability...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2012.01.003
更新日期:2012-04-01 00:00:00
abstract::This study tried to investigate the relationships between serum brain-derived neurotrophic factor (BDNF) protein levels and major depressive patients and discuss the effects of antidepressants on the serum BDNF protein levels. A total of 218 participants, including 111 patients with major depression (91 women) and 107...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2007.05.007
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:Recent genome-wide association studies revealed that Triggering receptor expressed on myeloid cells 2 (TREM2) was associated with Alzheimer's disease (AD) and other neurodegenerative diseases. We previously reported that TREM2 mRNA is highly expressed in leukocytes of AD patients compared to those in healthy...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2017.04.003
更新日期:2017-09-01 00:00:00
abstract::Electroconvulsive therapy (ECT) remains the most effective treatment of depression, though it is still unclear which of its type is the most beneficial. The aim of this study was to compare the formula-based right unilateral ECT (RUL) with the fronto-temporal bilateral ECT (BT), in terms of their efficacy, safety and ...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2020.12.002
更新日期:2021-01-01 00:00:00
abstract::Major depressive disorder (MDD) is characterized by the presence of disturbances in emotional processing. However, the neural correlates of these alterations, and how they may be affected by therapeutic interventions, remain unclear. The present study addressed these issues in a preliminary investigation using functio...
journal_title:Journal of psychiatric research
pub_type: 临床试验,杂志文章
doi:10.1016/j.jpsychires.2010.09.007
更新日期:2011-05-01 00:00:00
abstract::Cholesterol (CHL) and phospholipid (PL) levels in synaptosomal membranes in particular can have an impact on cell signalling. Alterations in peripheral CHL measures have been consistently reported in suicidal behaviour. As CHL and PL turnover in the brain are important in synapse maintenance and function, the objectiv...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2012.10.019
更新日期:2013-02-01 00:00:00
abstract::Urban vs. rural residence is commonly cited as a risk factor for depression and other mental disorders, but epidemiological evidence for this relationship in the US is inconclusive. We examined three consecutive annual samples (2009-2011) of adolescents (age 12-17, N = 55,583) and adults (age 18 and over, N = 116,459)...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2014.05.004
更新日期:2014-09-01 00:00:00
abstract::Several lines of evidence, including psychopathological, neurobiological, pharmacological and epidemiological data, supported the association between Anorexia Nervosa (AN) and Obsessive-Compulsive Disorder (OCD). The aim of the present study is to test the hypothesis of partial common genetic background of both diseas...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2012.12.015
更新日期:2013-06-01 00:00:00
abstract::There are very few magnetic resonance spectroscopy studies in anorexia nervosa and none of them with young adolescent patients. We studied 12 anorexia nervosa (DSM-IV) patients aged 11-17 consecutively admitted to an Eating Disorders Unit. An evaluation with laboratory data, psychopathological scales, magnetic resonan...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2006.09.013
更新日期:2007-12-01 00:00:00
abstract::Structural neuroimaging studies investigating amygdala volumes in patients suffering from major depression have yielded variable results. Discrepant findings across studies may be attributable in part to heterogeneity with respect to antidepressant medication and to lack of adequate control for the effects of total br...
journal_title:Journal of psychiatric research
pub_type: 杂志文章
doi:10.1016/j.jpsychires.2009.03.007
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVES:The DEX/CRH test has been proposed to be suitable as a biomarker for the prediction of treatment response in depression. METHODS:We performed the DEX/CRH test in 10 severely depressed male patients with melancholic features before initiation of antidepressant treatment with 20 mg fluoxetine. RESULTS:We fou...
journal_title:Journal of psychiatric research
pub_type: 临床试验,杂志文章
doi:10.1016/j.jpsychires.2010.04.010
更新日期:2010-12-01 00:00:00