Abstract：
:A latent class analysis paradigm for evaluating and developing diagnostic criteria was presented. How latent class analysis statistically models the conceptual structure of diagnostic systems was demonstrated. These models were then used to study the Taylor and Abrams diagnostic criteria for schizophrenia. The findings of this analysis were used in reanalyzing a previous study, yielding improved results. Finally, the nature of internal and external construct validity, and the particular appropriateness for diagnostic research of models with discrete variables was discussed.
journal_name
J Psychiatr Resjournal_title
Journal of psychiatric researchauthors
Young MAdoi
10.1016/0022-3956(82)90007-3subject
Has Abstractpub_date
1982-01-01 00:00:00pages
285-96issue
3eissn
0022-3956issn
1879-1379journal_volume
17pub_type
杂志文章abstract：:Repetitive transcranial magnetic stimulation (rTMS) has been found to ameliorate symptoms in major depression. However, its mechanism of action has to be further elucidated and the relationship between responses to rTMS and other antidepressant interventions except electroconvulsive therapy has not been investigated t...
journal_title：Journal of psychiatric research
pub_type： 临床试验,杂志文章
doi：10.1016/s0022-3956(01)00059-0
更新日期：2002-05-01 00:00:00
abstract：:Bipolar Disorder (BD) is one of the most severe psychiatric disorders. Despite adequate treatment, patients continue to have recurrent mood episodes, residual symptoms, and functional impairment. Some preclinical studies have shown that histone deacetylase inhibitors may act on manic-like behaviors. Neurotrophins have...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2014.11.003
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:Bipolar disorder may be associated with peripheral immune system dysfunction; however, results in individual studies are conflicting. Our aim was to systematically review evidence of peripheral cytokine alterations in bipolar disorder integrating findings from various affective states. METHODS:We conducted ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jpsychires.2013.05.018
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:We evaluated whether the association between Adult Attention-Deficit/Hyperactivity Disorder (ADHD) and Seasonal Affective Disorder (SAD) was mediated by the circadian rhythm. METHOD:Data of 2239 persons from the Netherlands Study of Depression and Anxiety (NESDA) were used. Two groups were compared: with cli...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2016.06.018
更新日期：2016-10-01 00:00:00
abstract：:Research investigating patterns of familial aggregation of psychiatric disorders has used the family history method in which a single family member reports on the psychiatric history of their relatives. This method is more efficient and less costly than the family study method, in which direct interviews are performed...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(92)90005-9
更新日期：1992-04-01 00:00:00
abstract：:Genetic factors contribute to the risk of psychopathology in many psychiatric conditions, but the specific genes are yet to be identified. Neurotransmitter alterations are implicated in the etiology of psychopathology based, in part, on studies of neurotransmitter receptors and their biosynthetic or degradative enzyme...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,评审
doi：10.1016/s0022-3956(03)00048-7
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVES:Clinical research projects gather large amounts of data. Typically, information is captured on paper source documents for later transcription to an electronic format, where responses can be checked, and errors, omissions, and inconsistencies can be resolved. These steps contribute delays, cost, and complexit...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2006.07.015
更新日期：2007-11-01 00:00:00
abstract：:Early discharge or reduced length of stay for inpatient psychiatric patients is related to increased readmission rates and worse clinical outcomes including increased risk for suicide. Trajectories of mental illness outcomes have been identified as an important method for predicting the optimal length of stay but the ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.07.001
更新日期：2020-11-01 00:00:00
abstract：:The current study aimed to describe the use of antipsychotics to clarify the gap between clinical guidelines and health care practice in Japan. We used data from the JMDC Claims Database (JMDC Inc., Tokyo, Japan), a nationwide claims database, from 2005 to 2016. Antipsychotics were defined as drugs coded as N05A with ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2020.05.012
更新日期：2020-08-01 00:00:00
abstract：:Patients with major depressive disorder (MDD) usually suffer from altered cognitive functions of episodic memory, working memory, mental processing speed and motor response. Diverse studies suggest that different antidepressant agents may improve cognitive functions in patients with MDD. The aim of this work is to stu...
journal_title：Journal of psychiatric research
pub_type： 临床试验,杂志文章
doi：10.1016/j.jpsychires.2008.10.015
更新日期：2009-06-01 00:00:00
abstract：:There is an emerging subjective-objective deficit paradox in schizotypy. Individuals with schizotypy report severe subjective complaints in several key functional domains commensurate with that of individuals with schizophrenia. However, objective assessments of the same domains show relatively intact performance. We ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2019.01.026
更新日期：2019-04-01 00:00:00
abstract：:It has been shown that antidepressants increase the expression of CREB (cAMP-response-element-binding-protein) and BDNF (brain derived neurotrophic factor) in vivo. Apparently inconsistent to these survival-promoting properties for many years antidepressants are known to induce apoptosis in various cell types in vitro...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/s0022-3956(02)00061-4
更新日期：2003-01-01 00:00:00
abstract：:Several lines of evidence suggest a dysregulation of the adrenocortical (HPA) system with hypersecretion of CRH is associated with suicidal behavior. However, controversial results have emerged from the determination of corticotropin-releasing hormone (CRH) concentrations in the lumbar cerebrospinal fluid (CSF) of sui...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/s0022-3956(01)00007-3
更新日期：2001-01-01 00:00:00
abstract：:Assuming that the experience of strong aversive tension might be an indicator of the extent of affect dysregulation within patients with borderline personality disorder (BPD), we sought to operationalize the duration and intensity of these phenomena. In addition we studied the relationship between aversive tension and...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/s0022-3956(01)00012-7
更新日期：2001-03-01 00:00:00
abstract：:Benzodiazepine hypnotics increase NREM sleep and alter its EEG by reducing delta (0.3-3 Hz) and increasing sigma (12-15 Hz) and beta (15-23 Hz) activity. We tested whether the nonbenzodiazepine hypnotic, zolpidem (10 mg), produced the same pattern of sleep and EEG changes as two "classical" benzodiazepines, triazolam ...
journal_title：Journal of psychiatric research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0022-3956(00)00038-8
更新日期：2000-11-01 00:00:00
abstract：:Generalized anxiety disorder (GAD) and substance use disorders (SUDs) are highly comorbid, and GAD-SUD comorbidity is associated with a host of poor psychosocial outcomes, including higher rates of hospitalization, disability, functional impairment, and inferior GAD and SUD treatment outcomes. Despite the noted severi...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2012.02.011
更新日期：2012-05-01 00:00:00
abstract：:Psychological distress and coping styles have been suggested to relate to altered function in the hypothalamic-pituitary-adrenal (HPA) axis, although there remains much to be understood about their relationships. High and low cortisol levels (or reactivity) both represent HPA axis dysfunction, with accumulated evidenc...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2010.02.007
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Structural neuroimaging studies revealed a consistent pattern of volumetric reductions in both hippocampus (HC) and anterior cingulate cortex (ACC) of individuals with major depressive episode(s) (MDE). This study investigated HC and ACC volume differences in currently depressed individuals (n = 150), indivi...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2018.04.008
更新日期：2018-07-01 00:00:00
abstract：:Schizophrenia (SCZ) is the result of DNA alterations and environmental factors, which together lead to differential protein expression and ultimately to the development of the illness. The diagnosis is based on clinical symptoms, and the molecular background of SCZ is not completely understood. The thalamus, whose dys...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2010.04.014
更新日期：2010-12-01 00:00:00
abstract：:One important target in the treatment of major depressive disorder (MDD) is the serotonin (5-hydroxytryptamine, 5-HT) system. Selective serotonin reuptake inhibitors (SSRI) are used to treat MDD. Yet, the mode of action of these drugs is not completely understood. There is evolving evidence for a role of glutamate in ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2010.06.005
更新日期：2011-02-01 00:00:00
abstract：:Suicidal behaviour poses a significant public health concern. Research into the factors that distinguish between the emergence of suicide ideation and the enactment of a suicide attempt is crucial. This study tests central tenets of the Integrated Motivational-Volitional Model of suicidal behaviour (IMV, O'Connor and ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2019.07.007
更新日期：2019-10-01 00:00:00
abstract：:This paper reviews problems associated with the concept of causation in interpreting relationships between altered biochemical measures and psychiatric states, and critically reanalyses claims for biochemical and genetic "markers" in depression and schizophrenia. ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/0022-3956(84)90025-6
更新日期：1984-01-01 00:00:00
abstract：:The anterior cingulate cortex (ACC) plays a major role in modulating executive control of attention. Here, 15 medication-nai ve patients with attention deficit/hyperactivity disorder (ADHD) and 10 carefully matched healthy controls were studied with 2D (1)H-magnetic resonance spectroscopic imaging (MRSI) of the ACC [B...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2007.06.006
更新日期：2008-06-01 00:00:00
abstract：:Gender Identity Disorder (GID) is characterized by a strong and persistent cross-gender identification that affects different aspects of behavior. Brain-derived neurotrophic factor (BDNF) plays a critical role in neurodevelopment and neuroplasticity. Altered BDNF-signaling is thought to contribute to the pathogenesis ...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2013.04.012
更新日期：2013-10-01 00:00:00
abstract：:A self-report version of the Lifetime History of Impulsive Behaviors (LHIB) interview was developed and its psychometric properties examined. Initially, forty-two personality disordered and 20 control subjects completed both the interview (I) and self-report (Q53) versions of the LHIB along with other self-report meas...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2011.11.008
更新日期：2012-03-01 00:00:00
abstract：:The investigation of neural substrates of autism spectrum disorder using neuroimaging has been the focus of recent literature. In addition, machine-learning approaches have also been used to extract relevant information from neuroimaging data. There are only few studies directly exploring the inter-regional structural...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2012.11.017
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:We explored interaction effects involving polymorphisms of targeted dopamine system genes and selected forms of childhood abuse (sexual, physical and emotional) acting upon severity of binge-eating and psychopathological symptoms in women with Bulimia-Spectrum Disorders (BSDs). METHODS:Women diagnosed with a...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2012.05.018
更新日期：2012-09-01 00:00:00
abstract：:A dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) axis represents a prominent finding in major depression, possibly related to a dysfunction of the corticosteroid receptor system. Antidepressants are involved in the restoration of the altered feed-back mechanism of the HPA-axis, probably via normaliza...
journal_title：Journal of psychiatric research
pub_type： 杂志文章
doi：10.1016/j.jpsychires.2011.03.007
更新日期：2011-09-01 00:00:00
abstract：:Suicide is an emerging, yet preventable global health issue associated with significant mortality. Identification of underlying risk factors and antecedents may inform preventive strategies and interventions. This study serves to provide an updated meta-analysis examining the extent of association of early life sexual...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,meta分析
doi：10.1016/j.jpsychires.2018.02.001
更新日期：2018-04-01 00:00:00
abstract：:Analysis of the distribution of diagnoses in families (segregation analysis) has not, so far, advanced us toward the goal of resolving the inheritance of the major psychiatric disorders. Recent advances in genetics, particularly the development of new molecular genetic linkage methods, have made it, at least theoretic...
journal_title：Journal of psychiatric research
pub_type： 杂志文章,评审
doi：10.1016/0022-3956(87)90103-8
更新日期：1987-01-01 00:00:00
