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Generation of two induced pluripotent stem cell lines NCCSi005A and NCCSi006A from CD4+T cells of healthy individuals of Indian origin.

Abstract：

:Human induced pluripotent stem cell-lines (iPSCs) of Indian origin NCCSi005A and NCCSi006A were established by reprogramming of CD4+T cells, isolated from the peripheral blood mononuclear cells (PBMCs) of two healthy female donors. Reprogramming was achieved using integration free, Sendai viral vector system expressing cocktail of transcription factors KOS, hc-MYC and hKLF4. Both the established cell-lines showed alkaline phosphatase activity, expressed stemness markers, exhibited normal female karyotype and displayed potential for tri-lineage differentiation. These two CD4+T cells derived cell-lines represent valuable resource as control iPSC cell lines of Indian origin.

journal_name

Stem Cell Res

journal_title

Stem cell research

authors

Khan M,Zende S,Vaidyanath A,Avatade R,Shiras A

doi

10.1016/j.scr.2019.101506

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

101506

eissn

1873-5061

issn

1876-7753

pii

S1873-5061(19)30136-9

journal_volume

39

pub_type

杂志文章

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