当前位置： SCI文献检索 > Stem Cell Research期刊下所有文献 > Generation of a NKX2.1 - p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4).

Generation of a NKX2.1 - p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4).

Abstract：

:Tumor protein p63 (p63) encodes for a transcription factor of the p53 family and is a marker for respiratory basal cells. Based on a NKX2.1 knock-in reporter cell line from human induced pluripotent stem cells (hiPSCs) (MHHi06-A-2) we established a NKX2.1/p63 double transgenic knock-in reporter cell line using TALEN technology. The reporter enables the optimization and monitoring of hiPSC differentiation towards NKX2.1/p63 double positive cells as well as enrichment for single or double positive cells.

journal_name

Stem Cell Res

journal_title

Stem cell research

authors

Drick N,Sahabian A,Pongpamorn P,Merkert S,Göhring G,Welte T,Martin U,Olmer R

doi

10.1016/j.scr.2019.101659

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

101659

eissn

1873-5061

issn

1876-7753

pii

S1873-5061(19)30289-2

journal_volume

42

pub_type

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