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Establishment of an induced pluripotent stem cell line ZZUi003-A from a 65-year-old male with sporadic Parkinson's disease.

Abstract：

:Skin fibroblasts were collected from a 65-year-old male patient with sporadic Parkinson's disease. Induced pluripotent stem cells were reprogrammed with human reprogramming factors (KMOSL) using the messenger RNA reprogramming protocol. The transgene-free iPSC line showed pluripotency, displayed normal karyotype, and could form embryoid bodies in vitro and differentiate into all 3 germ layers in vivo. This iPSC line can be a useful cellular model for studying the mechanism of Parkinson's disease.

journal_name

Stem Cell Res

journal_title

Stem cell research

authors

Zheng X,Zhu Z,Chen K,Guo S,Liu T,Liu H

doi

10.1016/j.scr.2017.07.004

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

119-121

eissn

1873-5061

issn

1876-7753

pii

S1873-5061(17)30128-9

journal_volume

23

pub_type

杂志文章

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