Abstract:
:Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM.
journal_name
Stem Cell Resjournal_title
Stem cell researchauthors
Bai X,Yang X,Cheng Y,Chen Ldoi
10.1016/j.scr.2018.101369subject
Has Abstractpub_date
2019-01-01 00:00:00pages
101369eissn
1873-5061issn
1876-7753pii
S1873-5061(18)30304-0journal_volume
34pub_type
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journal_title:Stem cell research
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journal_title:Stem cell research
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journal_title:Stem cell research
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journal_title:Stem cell research
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abstract::The European Bank for induced Pluripotent Stem Cells (EBiSC), a non-profit repository for storage, banking, Quality Control (QC) and subsequent distribution of research-grade human induced Pluripotent Stem Cell (iPSC) lines, has centralised iPSC lines generated internationally across >35 disease areas and made them av...
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journal_title:Stem cell research
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journal_title:Stem cell research
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journal_title:Stem cell research
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journal_title:Stem cell research
pub_type: 杂志文章,评审
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