Abstract:
:A DAND5-control human iPSC line was generated from the urinary cells of a phenotypically normal donor. Exfoliated renal epithelial (RE) cells were collected and reprogrammed into iPSCs using Sendai virus reprogramming system. The pluripotency, in vitro differentiation potential, karyotype stability, and the transgene-free status of generated iPSC line were analyzed and confirmed. This cell line can be exploited as a control iPSC line to better understand the mechanisms involved in DAND5-associated cardiac disease.
journal_name
Stem Cell Resjournal_title
Stem cell researchauthors
Pars S,Cristo F,Inácio JM,Rosas G,Carreira IM,Melo JB,Mendes P,Martins DS,de Almeida LP,Maio J,Anjos R,Belo JAdoi
10.1016/j.scr.2018.04.015subject
Has Abstractpub_date
2018-05-01 00:00:00pages
202-206eissn
1873-5061issn
1876-7753pii
S1873-5061(18)30116-8journal_volume
29pub_type
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