Pluronic F-127: An Efficient Delivery Vehicle for 3-(1'-hexyloxy)ethyl-3-devinylpyropheophorbide-a (HPPH or Photochlor).

abstract：:Cyclooxygenase (COX)-2 inhibitors are known to be used as chemopreventative agents against certain malignancies. Thus far, there has been very limited information on whether COX-2 inhibitors protect against chronic narrow-band UVB (NB-UVB)-induced immunosuppression. The present study investigated the effect of nonsele...

journal_title：Photochemistry and photobiology

authors： Wu Y,Tai CL,Wei H,He F,Wang Y,Zhao Y,Chen HD

更新日期：2008-03-01 00:00:00

abstract：:In order to gain insight into the preactivation of merocyanine 540 (MC540) 1 for the photodynamic therapy (Gulliya et al., 1990a, Photochem. Photobiol. 52, 831-838) its photo-oxidation was investigated. After irradiation of MC540 1 on a preparative scale three main photodegradation products were isolated with 16-20% y...

journal_title：Photochemistry and photobiology

authors： Franck B,Schneider U

更新日期：1992-08-01 00:00:00

abstract：:Psoralen is a furocoumarin natural product that intercalates within DNA and forms covalent adducts when activated by ultraviolet radiation. It is well known that this property contributes to psoralen's clinical efficacy in several disease contexts, which include vitiligo, psoriasis, graft-versus-host disease and cutan...

journal_title：Photochemistry and photobiology

authors： Buhimschi AD,Gooden DM,Jing H,Fels DR,Hansen KS,Beyer WF Jr,Dewhirst MW,Walder H,Gasparro FP

更新日期：2020-09-01 00:00:00

abstract：:Excessive sun exposure can cause sunburn, suntan, skin photoaging, and even skin cancer. Skin photoaging conflicts with the human pursuit of a young and beautiful appearance. Some research data indicate that the incidence of skin cancer in the Chinese has been increasing, although it remains lower than in whites. To e...

journal_title：Photochemistry and photobiology

authors： Wan M,Hu R,Li Y,Wang Y,Xie X,Yue P,Guan L,Lai W

更新日期：2016-09-01 00:00:00

abstract：:The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticles based on poly(D,L-lactide-co-glycolide) (PLGA) (50:50 PLGA and 75:...

journal_title：Photochemistry and photobiology

authors： Konan YN,Chevallier J,Gurny R,Allémann E

更新日期：2003-06-01 00:00:00

abstract：:In studies of the biological effects of UV radiation, ozone depletion can be mimicked by performing the study under ambient conditions and adding radiation with UV-B lamps. We evaluated this methodology at three different locations along a latitudinal gradient: Rimouski (Canada), Ubatuba (Brazil) and Ushuaia (Argentin...

journal_title：Photochemistry and photobiology

authors： Díaz S,Camilión C,Escobar J,Deferrari G,Roy S,Lacoste K,Demers S,Belzile C,Ferreyra G,Gianesella S,Gosselin M,Nozais C,Pelletier E,Schloss I,Vernet M

更新日期：2006-07-01 00:00:00

abstract：:In this work, we have quantified for the first time the fluorescence and singlet oxygen quantum yields of a silicon(IV) phthalocyanine bound to the surface of zeolite L nanocrystals. The photophysical properties were correlated with the absorption spectra and the morphology of the nanoparticles, and most importantly, ...

journal_title：Photochemistry and photobiology

authors： Grüner M,Siozios V,Hagenhoff B,Breitenstein D,Strassert CA

更新日期：2013-11-01 00:00:00

abstract：:Carp (Cyprinus carpio) were repeatedly exposed to 0, 60, 120 and 240 mJ/cm2 ultraviolet B (UVB) radiation three times in 1 week (short-term exposure) or 12 times in 4 weeks (long-term exposure). The effect of UVB on the functioning of the carp immune system was studied on day 2 after the final irradiation. After short...

journal_title：Photochemistry and photobiology

authors： Markkula SE,Salo HM,Immonen AK,Jokinen EI

更新日期：2005-05-01 00:00:00

abstract：:Experimental studies have recently demonstrated that fluorescence emission can be quenched by laser light pulses from modern high-repetition rate lasers, a phenomenon we call "light quenching." In this overview article, we describe the possible effects of light quenching on the steady-state and time-resolved intensity...

journal_title：Photochemistry and photobiology

authors： Lakowicz JR,Gryczyński I,Kuśba J,Bogdanov V

更新日期：1994-12-01 00:00:00

abstract：:Near-infrared spectroscopy has been used to quantify the composition of healthy female breast tissue in vivo. By collecting transillumination spectra in the wavelength range 680-1100 nm at 7-9 positions on the breasts of five female volunteers, an attempt was made to quantify the intra- and intersubject variability of...

journal_title：Photochemistry and photobiology

authors： Quaresima V,Matcher SJ,Ferrari M

更新日期：1998-01-01 00:00:00

abstract：:The design, synthesis and application of a new fluorescent-labeling reagent for collagen has been developed as a prerequisite for the design of a photoactivated collagen-crosslinking compound for surgical wound closure. The amine groups in collagen are the targets of a rational design for a new fluorophore because nat...

journal_title：Photochemistry and photobiology

authors： Timberlake GT,Reddy GK,Stehno-Bittel L,Weber JF,Amslinger S,Givens RS

更新日期：2002-11-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:Cryptococus gattii is an emergent primary human pathogen that causes meningismus, papilledema, high intracranial pressure and focal involvement of the central nervous system in immunocompetent hosts. Prolonged antifungal therapy is the conventional treatment, but it is highly toxic, selects for resistant strains, cont...

journal_title：Photochemistry and photobiology

authors： Soares BM,Alves OA,Ferreira MV,Amorim JC,Sousa GR,Silveira Lde B,Prates RA,Avila TV,Baltazar Lde M,de Souza Dda G,Santos DA,Modolo LV,Cisalpino PS,Pinotti M

更新日期：2011-03-01 00:00:00

abstract：:The excited-state intramolecular H-atom transfer reactions of hypocrellins B and A are compared by using time-resolved absorption and fluorescence upconversion techniques. The hypocrellin B photophysics are well described by a simple model involving one ground-state species and excited-state forward and reverse H-atom...

journal_title：Photochemistry and photobiology

authors： Datta A,Smirnov AV,Wen J,Chumanov G,Petrich JW

更新日期：2000-02-01 00:00:00

abstract：:Intracellular targets for the photosensitizer alpha-terthienyl (alpha T) were examined by fluorescence microscopy and microfluorospectrometry using human nonkeratinized buccal cells. Intracellular distribution of alpha T was observed as fluorescent patches widely dispersed in the cytoplasm. The distribution of the flu...

journal_title：Photochemistry and photobiology

authors： Sasaki M,Koyama S,Tokiwa K,Fujita H

更新日期：1993-05-01 00:00:00

abstract：:The ultraviolet (UV) component of solar radiation is the driving force of life on earth, but it can cause photoaging and skin cancer. In this study, we investigated the effects of the glucosamine-derivative 2-(N-Acetyl)-L-phenylalanylamido-2-deoxy-β-D-glucose (NAPA) on human primary fibroblasts (FBs) stimulated in vit...

journal_title：Photochemistry and photobiology

authors： Lopreiato M,Cocchiola R,Falcucci S,Leopizzi M,Cardone M,Di Maio V,Brocco U,D'Orazi V,Calvieri S,Scandurra R,De Marco F,Scotto d'Abusco A

更新日期：2020-01-01 00:00:00

abstract：:Stratospheric ozone depletion has caused an increase in the amount of ultraviolet-B (UV-B) radiation reaching the earth's surface. Numerous investigations have demonstrated that the effect of UV-B enhancements on plants includes reduction in grain yield, alteration in species competition, susceptibility to disease and...

journal_title：Photochemistry and photobiology

authors： Gao W,Zheng Y,Slusser JR,Heisler GM,Grant RH,Xu J,He D

更新日期：2004-07-01 00:00:00

abstract：:We have been able to identify a blue fluorophore from the low-molecular weight soluble fraction of human adult nondiabetic brunescent cataract lenses as xanthurenic acid 8-O-beta-D-glucoside (XA8OG) (excitation = 338 nm and emission = 440 nm). To determine the role of this fluorophore in the lens, we have examined its...

journal_title：Photochemistry and photobiology

authors： Thiagarajan G,Shirao E,Ando K,Inoue A,Balasubramanian D

更新日期：2002-09-01 00:00:00

abstract：:A solution of iodouracil (0.2 mg/mL) and KI (0.1 M) in 0.23 M borate buffer (pH 7) forms triiodide upon exposure to UVB. In the presence of thyodene, the blue starch-iodine complex is formed, the intensity of which is proportional to the amount of UVB exposure. Studies were conducted using either a sunlamp or solar ir...

journal_title：Photochemistry and photobiology

authors： Rahn R,Lee MA

更新日期：1998-08-01 00:00:00

abstract：:Exposure to ultraviolet radiation is closely linked to the development of skin cancers in humans. The ultraviolet B (UVB) radiation wavelength (280-320 nm), in particular, causes DNA damage in epidermal keratinocytes, which are linked to the generation of signature premalignant mutations. Interactions between dermal f...

journal_title：Photochemistry and photobiology

authors： Fernandez TL,Van Lonkhuyzen DR,Dawson RA,Kimlin MG,Upton Z

更新日期：2014-11-01 00:00:00

abstract：:Photodimerization of cocrystals of four bispyridylethylenes and two stilbazoles with urea as a template in the solid state has been investigated following our success with thiourea. Four investigated olefins photodimerized quantitatively to a single dimer in the crystalline state only. The reactivity of urea-olefin cr...

journal_title：Photochemistry and photobiology

authors： Bhogala BR,Captain B,Ramamurthy V

更新日期：2015-05-01 00:00:00

abstract：:Many biomolecules contain photoactive reducing agents, such as reduced nicotinamide adenine dinucleotide (NADH) and 6-thioguanine (6-TG) incorporated into DNA through drug metabolism. These reducing agents may produce reactive oxygen species under UVA irradiation or act as electron donors in various media. The interac...

journal_title：Photochemistry and photobiology

authors： Quinones M,Zhang Y,Riascos P,Hwang HM,Aker WG,He X,Gao R

更新日期：2014-03-01 00:00:00

abstract：:The photochemical reactions of the 1-deaza derivative of riboflavin (RF) have been studied by sub-ps time-resolved fluorescence spectroscopy. A potential effect of the solvent polarity and hydrogen bonding capability on the excited state (ES) dynamics was tested by measuring 1-deaza RF in water and, after acetylation ...

journal_title：Photochemistry and photobiology

authors： Slavov C,Mansurova M,Holzwarth AR,Gärtner W

更新日期：2010-01-01 00:00:00

abstract：:Reactive nitrogen species, produced during the process of inflammation induced by various factors including UV radiation, modify amino acids in crucial proteins. It is assumed that skin tissue is more likely to be modified, as it is located at the outer layer of a body that is exposed to UV radiation on a daily basis....

journal_title：Photochemistry and photobiology

authors： Ishitsuka Y,Maniwa F,Koide C,Douzaki N,Kato Y,Nakamura Y,Osawa T

更新日期：2007-05-01 00:00:00

abstract：:These experiments tested the hypothesis that phototropic bending arises when a light gradient across the stem differentially inhibits cell elongation because of direct inhibition of cell elongation by light (the Blaauw hypothesis). Continuous irradiation of dark-grown cucumber seedlings (Cucumis sativus L.) with unil...

journal_title：Photochemistry and photobiology

authors： Cosgrove DJ

更新日期：1985-01-01 00:00:00

abstract：:Types of photoreceptor cells in the retinas of 36 species of vertebrates (5 classes, 14 orders) were investigated immunocytochemically with monoclonal antibodies against chicken iodopsin (Io-mAb) and antiserum against bovine rhodopsin (Rh-As). In mammals, Rh-As labeled the outer segments of some photoreceptor cells in...

journal_title：Photochemistry and photobiology

authors： Kawata A,Oishi T,Fukada Y,Shichida Y,Yoshizawa T

更新日期：1992-12-01 00:00:00

abstract：:Adaptability to a broad range of environments together with relatively high resistance to antibiotics and to disinfectants makes Pseudomonas aeruginosa a concern in hospitals and in public health. We investigated whether UVA-mediated photochemical inactivation of P. aeruginosa could be accomplished with high efficienc...

journal_title：Photochemistry and photobiology

authors： Sagripanti JL,Grote G,Niederwöhrmeier B,Hülseweh B,Marschall HJ

更新日期：2012-01-01 00:00:00

abstract：:Quantum yields for the formation of superoxide ions, O2-., and singlet oxygen, 1O2, were determined during the photolyses of gilvocarcin M (GM) in air-saturated dry dimethylsulfoxide (DMSO) and in 45:55 (vol/vol) DMSO-water mixtures. The quantum yield for the photoreduction of methyl viologen by GM in nitrogen-saturat...

journal_title：Photochemistry and photobiology

authors： Alegría AE,Zayas L,Guevara N

更新日期：1995-09-01 00:00:00

abstract：:Photodynamic therapy (PDT) with photosensitizer verteporfin is a clinically approved vascular disrupting modality that is currently in clinical trial for cancer treatment. In this study, we evaluated PDT in combination with either mTORC1 inhibitor rapamycin or mTORC1/C2 dual inhibitor AZD2014 for therapeutic enhanceme...

journal_title：Photochemistry and photobiology

authors： Kraus D,Palasuberniam P,Chen B

更新日期：2020-03-01 00:00:00

abstract：:Restenosis results from intimal hyperplasia and constrictive remodeling following cardiovascular interventions. Photodynamic therapy (PDT) has been shown to inhibit intimal hyperplasia in vivo by preventing neointimal repopulation of the treated vessel. This study was undertaken in an attempt to further dissect the me...

journal_title：Photochemistry and photobiology

authors： Waterman PR,Overhaus M,Heckenkamp J,Nigri GR,Fungaloi PF,Landis ME,Kossodo SC,LaMuraglia GM

更新日期：2002-01-01 00:00:00