Therapeutic Enhancement of Verteporfin-mediated Photodynamic Therapy by mTOR Inhibitors.

abstract：:2-Aminoacetophenone (AAP) was recognized as the key compound for the so-called untypical aging off-flavor (UTA) in Vitis vinifera wines. In this study, it was shown that AAP can be formed by photooxidation of free and protein-bound tryptophan (TRP) in combination with a subsequent storage in model wine. Solutions of T...

journal_title：Photochemistry and photobiology

authors： Horlacher N,Schwack W

更新日期：2014-11-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a way of treating malignant tumors and hyperproliferative diseases. It is based on the use of photosensitizer, herein the chlorophyll a (chl a), and a light of an appropriate wavelength. The interaction of the photosensitizer (PS) with the light produces reactive oxygen species (ROS), pow...

journal_title：Photochemistry and photobiology

authors： Cellamare BM,Fini P,Agostiano A,Sortino S,Cosma P

更新日期：2013-03-01 00:00:00

abstract：:Photodynamic therapy (PDT) uses laser light to activate a photosensitizer that has been absorbed preferentially by cancer cells after systemic administration. A phototoxic reaction ensues resulting in cell death and tissue necrosis. Some cells, however, may survive PDT. This study was performed to determine if survivi...

journal_title：Photochemistry and photobiology

authors： Hornung R,Walt H,Crompton NE,Keefe KA,Jentsch B,Perewusnyk G,Haller U,Köchli OR

更新日期：1998-10-01 00:00:00

abstract：:The photoprocesses of berberine, palmatine, coralyne, sanguinarine, flavopereirine and ellipticine were studied in several solvents. The quantum yields Φ(Δ) of singlet molecular oxygen formation of berberine, palmatine and sanguinarine are moderate in dichloromethane (0.2-0.6) and much smaller in acetonitrile or trifl...

journal_title：Photochemistry and photobiology

authors： Görner H,Miskolczy Z,Megyesi M,Biczók L

更新日期：2011-03-01 00:00:00

abstract：:The individual tryptophanyl contributions to the near-ultraviolet dichroic activity of apomyoglobin in its native conformation have been resolved. This was accomplished by comparing the spectra of two classes of apomyoglobin with different aromatic residue contents and observing the effect of a specific modification o...

journal_title：Photochemistry and photobiology

authors： Sirangelo I,Irace G,Bismuto E

更新日期：1994-06-01 00:00:00

abstract：:The effect of netropsin on the oxidative reactions of duplex DNA was examined. One-electron oxidation of DNA creates a radical cation that migrates through duplex DNA and reacts primarily at GG steps. Netropsin is a dication that specifically binds primarily by hydrogen bonding in the minor groove at sites that have f...

journal_title：Photochemistry and photobiology

authors： Roberts LW,Schuster GB

更新日期：2004-11-01 00:00:00

abstract：:We report the spectroscopic properties of fluorescein, x-rhodamine, tetramethyl-rhodamine, attached to single strand, duplex DNA, and to the digestion products by DNAse I. The properties reported include: molar absorptivity, quantum yield, absorbance and fluorescence spectra, fluorescence lifetime, intrinsic lifetime ...

journal_title：Photochemistry and photobiology

authors： Delgadillo RF,Parkhurst LJ

更新日期：2010-03-01 00:00:00

abstract：:During the past several years there has been debate about the origins of nonexponential intensity decays of intrinsic tryptophan (trp) fluorescence of proteins, especially for single tryptophan proteins (STP). In this review we summarize the data from diverse sources suggesting that time-dependent spectral relaxation ...

journal_title：Photochemistry and photobiology

authors： Lakowicz JR

更新日期：2000-10-01 00:00:00

abstract：:Photodamage to the endoplasmic reticulum (ER) can initiate a death pathway termed paraptosis. The "canonical" model of paraptosis, initiated by certain drugs and other stimuli, requires a brief interval of protein synthesis, involves the action of MAP kinases and can be followed by biochemical markers. The latter incl...

journal_title：Photochemistry and photobiology

authors： Kessel D

更新日期：2020-09-01 00:00:00

abstract：:Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectanc...

journal_title：Photochemistry and photobiology

authors： Marchesini R,Brambilla M,Clemente C,Maniezzo M,Sichirollo AE,Testori A,Venturoli DR,Cascinelli N

更新日期：1991-01-01 00:00:00

abstract：:A new type of photochromic molecule that can be used for diffusion coefficient (D) measurements of various proteins in solution is described. The absorption spectrum of this molecule is changed upon photoexcitation by the trans-cis isomerization reaction. Target proteins were labeled by this photochromic molecule in t...

journal_title：Photochemistry and photobiology

authors： Eitoku T,Terazima M

更新日期：2008-07-01 00:00:00

abstract：:The energy and oscillator strength of electronic transitions of chlorophyll (Chl)-amino acid complexes were calculated by using molecular orbital methods. The energies varied widely with coordinated amino acids and the difference between the maximum and minimum energy was about 830 cm-1. This energy difference was com...

journal_title：Photochemistry and photobiology

authors： Nishigaki A,Ohshima S,Nakayama K,Okada M,Nagashima U

更新日期：2001-03-01 00:00:00

abstract：:Proton magnetic resonance imaging (MRI) and histological methods were used to evaluate photodynamic therapy (PDT)-induced hemorrhagic necrosis in the murine M1 tumor within 72 h of treatment of male DBA/2 mice. The effects of three photosensitizing drugs were investigated: Photofrin (n = 4), Zn (II) phthalocyanine (n ...

journal_title：Photochemistry and photobiology

authors： Winsborrow BG,Grondey H,Savoie H,Fyfe CA,Dolphin D

更新日期：1997-12-01 00:00:00

abstract：:In this work, the changes in isoflavone levels and the expression of genes involved in their biosynthesis were studied in two Astragalus by UPLC-MS and real-time PCR after 10 days of UV-B treatment (λmax  = 313 nm, 804 J m-2 ). Isoflavones were significantly induced by UV-B irradiation. The influence might be activate...

journal_title：Photochemistry and photobiology

authors： Liu Y,Liu J,Wang Y,Abozeid A,Tian DM,Zhang XN,Tang ZH

更新日期：2018-01-01 00:00:00

abstract：:In this study our aim was to determine the biophysical values of constitutive skin color in Caucasians and to define the correlation between skin color and phototype assessed according to the Fitzpatrick method. Constitutive skin color was measured on the buttock, with a Minolta CR-200 colorimeter, in a population-of ...

journal_title：Photochemistry and photobiology

authors： Rubegni P,Cevenini G,Flori ML,Fimiani M,Stanghellini E,Molinu A,Barbini P,Andreassi L

更新日期：1997-02-01 00:00:00

abstract：:The aim of this investigation is the evaluation of DNA interaction of with tetraruthenated porphyrin (TRP) and of DNA damage in the presence of light. Direct-fluorescence and electronic absorption measurements after incubation of DNA with TRP indicate strong binding between pBR322 DNA or calf thymus DNA with the modif...

journal_title：Photochemistry and photobiology

authors： Onuki J,Ribas AV,Medeiros MH,Araki K,Toma HE,Catalani LH,Di Mascio P

更新日期：1996-03-01 00:00:00

abstract：:Photodynamic therapy (PDT) is an established therapeutic modality that uses nonionizing near-infrared light to activate photocytotoxicity of endogenous or exogenous photosensitizers (PSs). An ongoing avenue of cancer research involves leveraging PDT to stimulate antitumor immune responses; however, these effects appea...

journal_title：Photochemistry and photobiology

authors： Kercher EM,Nath S,Rizvi I,Spring BQ

更新日期：2020-03-01 00:00:00

abstract：:In the present work, we study the photodynamic action of cercosporin (cerco), a naturally occurring photosensitizer, on human cancer multicellular spheroids. U87 spheroids exhibit double the uptake of cerco than T47D and T98G spheroids as shown by flow cytometry on the single cell level. Moreover, cerco is efficiently...

journal_title：Photochemistry and photobiology

authors： Grigalavicius M,Mastrangelopoulou M,Arous D,Juzeniene A,Ménard M,Skarpen E,Berg K,Theodossiou TA

更新日期：2020-05-01 00:00:00

abstract：:Among beetle luciferases, the pH-sensitive firefly luciferases have been studied extensively. Much less is known about pH-insensitive luciferases, which include click beetle and railroad worm luciferases. Previously, we found that the residues R215 and T226 (N230) are important for green light emission. Here we show t...

journal_title：Photochemistry and photobiology

authors： Viviani VR,Uchida A,Viviani W,Ohmiya Y

更新日期：2002-11-01 00:00:00

abstract：:Pyocyanin (PyO-) (1-hydroxy-5-methylphenazine) is a cytotoxic compound secreted by Pseudomonas aeruginosa, an omnipresent bacterium and a human pathogen. We report that visible light illumination in the presence of rose bengal, or riboflavin, in aerated solutions (pH 7.0-7.2) induces irreversible loss of the pigment's...

journal_title：Photochemistry and photobiology

authors： Reszka KJ,Denning GM,Britigan BE

更新日期：2006-03-01 00:00:00

abstract：:Photoexcitation to generate triplet state has been proved to be the main photoreaction in homogeneous system for many benzoquinone derivatives, including oxidized coenzyme Q (CoQ) and its analogs. In the present study, microemulsion of CoQ, a heterogeneous system, is employed to mimic the distribution of CoQ in biomem...

journal_title：Photochemistry and photobiology

authors： Li K,Wang M,Wang J,Zhu R,Sun D,Sun X,Wang SL

更新日期：2013-01-01 00:00:00

abstract：:The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticles based on poly(D,L-lactide-co-glycolide) (PLGA) (50:50 PLGA and 75:...

journal_title：Photochemistry and photobiology

authors： Konan YN,Chevallier J,Gurny R,Allémann E

更新日期：2003-06-01 00:00:00

abstract：:As our understanding of the role of UV in causing skin cancer continues to expand, researchers and clinicians must continue to remain up to date on the various means by which UV exposure can be quantified. The purpose of this article was to review the current methods used to measure lifetime exposure to UV and to summ...

journal_title：Photochemistry and photobiology

authors： Worswick SD,Cockburn M,Peng D

更新日期：2008-11-01 00:00:00

abstract：:Vacuum UV (VUV) process is an incipient advanced oxidation process, which can be used for water treatment. This process relies on the formation of hydroxyl radicals through the VUV-induced photolysis of water. In particular, the use of ozone-generating mercury vapor lamps, which emit 10% of the radiation at 185 nm and...

journal_title：Photochemistry and photobiology

authors： Duca C,Imoberdorf G,Mohseni M

更新日期：2014-01-01 00:00:00

abstract：:Solar ultraviolet-B radiation (UVB) is essential for epidermal vitamin D production. We aimed to quantitate the relationship between personal solar UV exposure and serum 25hydroxy vitamin D (25[OH]D) concentration. Blood was collected for 25(OH)D analysis in 207 South Australian adults aged 27-61 years. At the time of...

journal_title：Photochemistry and photobiology

authors： Nair-Shalliker V,Clements M,Fenech M,Armstrong BK

更新日期：2013-01-01 00:00:00

abstract：:Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone with a structural resemblance to tryptophan. Its fluorescence is solvent dependent and strongly quenched in the presence of oxygen. Fluorescence quenching in aqueous and organic solutions have been studied in the presence of different quenchers....

journal_title：Photochemistry and photobiology

authors： Rath MC,Mahal HS,Mukherjee T

更新日期：1999-03-01 00:00:00

abstract：:This paper analyzes the influence of infrared radiation (IR) on regeneration, after autotomy of limb buds of Neohelice granulata and consequently the time molt. Eyestalks were ablated to synchronize the start of molt. Afterward, animals were autotomized of five pereopods and divided into control and irradiated groups....

journal_title：Photochemistry and photobiology

authors： Gonzalez VC,Lena AB,Espindola WA,de Souza Votto AP,Jorge MB,de Moraes Vaz Batista Filgueira D,Bianchini A,Sérgio Varela Júnior A,Nery LE,Trindade GS

更新日期：2009-09-01 00:00:00

abstract：:In photodynamic therapy with topically applied delta-aminolevulinic acid porphyrins are acting as photosensitizers. The profile of porphyrin metabolites in normal or in neoplastic skin after administration of delta-aminolevulinic acid has not been determined in detail yet. Thus, to study porphyrin biosynthesis in huma...

journal_title：Photochemistry and photobiology

authors： Fritsch C,Batz J,Bolsen K,Schulte KW,Zumdick M,Ruzicka T,Goerz G

更新日期：1997-07-01 00:00:00

abstract：:Generating accurate population-specific public health messages regarding sun protection requires knowledge about seasonal variation in sun exposure in different environments. To address this issue for a subtropical area of Australia, we used polysulphone badges to measure UVR for the township of Nambour (26 degrees la...

journal_title：Photochemistry and photobiology

authors： Neale RE,Hamilton AR,Janda M,Gies P,Green AC

更新日期：2010-03-01 00:00:00

abstract：:Organisms living in coastal waters are exposed to anthropogenic contaminants from terrestrial drainage, ice melting and maritime traffic and to enhanced UVB radiation (UVBR; 280-320 nm) caused by decreased concentrations of ozone in the stratosphere. This article reviews available information about the combined effect...

journal_title：Photochemistry and photobiology

authors： Pelletier E,Sargian P,Payet J,Demers S

更新日期：2006-07-01 00:00:00