Psoralen Derivatives with Enhanced Potency.

abstract：:Ultraviolet radiation can inhibit immune responses locally as well as systemically. Such effects have been measured in animals and humans exposed to ultraviolet B (wavelength 280-315 nm) (UVB) and ultraviolet A (315-400 nm) (UVA). The precise wavelength dependence is important for the identification of possible molecu...

journal_title：Photochemistry and photobiology

authors： Garssen J,de Gruijl F,Mol D,de Klerk A,Roholl P,Van Loveren H

更新日期：2001-04-01 00:00:00

abstract：:Intracellular targets for the photosensitizer alpha-terthienyl (alpha T) were examined by fluorescence microscopy and microfluorospectrometry using human nonkeratinized buccal cells. Intracellular distribution of alpha T was observed as fluorescent patches widely dispersed in the cytoplasm. The distribution of the flu...

journal_title：Photochemistry and photobiology

authors： Sasaki M,Koyama S,Tokiwa K,Fujita H

更新日期：1993-05-01 00:00:00

abstract：:In photodynamic therapy with topically applied delta-aminolevulinic acid porphyrins are acting as photosensitizers. The profile of porphyrin metabolites in normal or in neoplastic skin after administration of delta-aminolevulinic acid has not been determined in detail yet. Thus, to study porphyrin biosynthesis in huma...

journal_title：Photochemistry and photobiology

authors： Fritsch C,Batz J,Bolsen K,Schulte KW,Zumdick M,Ruzicka T,Goerz G

更新日期：1997-07-01 00:00:00

abstract：:Photoactive materials based on dye molecules incorporated into thin films or bulk solids are useful for applications as photosensitization, photocatalysis, solar cell sensitization and fluorescent labeling, among others. In most cases, high concentrations of dyes are desirable to maximize light absorption. Under these...

journal_title：Photochemistry and photobiology

authors： Rodríguez HB,San Román E

更新日期：2013-11-01 00:00:00

abstract：:The energetic characteristics of selected reaction steps in the bacterial luciferase-catalyzed luminescence reaction were examined by computation using the MNDO-PM3 method. Specifically, a three-step model was proposed to account for the reaction between oxygen and reduced riboflavin 5'-phosphate (1,5H2-FMN) to genera...

journal_title：Photochemistry and photobiology

authors： Wada N,Sugimoto T,Watanabe H,Tu SC

更新日期：1999-07-01 00:00:00

abstract：:Current conditions of 2-11 kJ m(-2) day(-1) of UV-B radiation and temperatures of >30 degrees C during flowering in cotton cultivated regions are projected to increase in the future. A controlled environment study was conducted in sunlit growth chambers to determine the effects of UV-B radiation and temperature on phy...

journal_title：Photochemistry and photobiology

authors： Reddy KR,Kakani VG,Zhao D,Koti S,Gao W

更新日期：2004-05-01 00:00:00

abstract：:Photolysis of 6-chloro-1,3-dimethyluracil and mesitylene in the presence of trifluoroacetic acid (TFA) at low temperature gave 1,3,5,7,9- and 1,3,6,8,10-pentamethylcyclooctapyrimidine-2,4-diones (1b, 1c). Sequential photoreaction of the former (1b) resulted in the formation of 9,11-diazapentacyclo[6.4.0.0(1,3).0(2,5)....

journal_title：Photochemistry and photobiology

authors： Ohkura K,Nishijima K,Seki K

更新日期：2001-09-01 00:00:00

abstract：:Blue visible light damage to retinal pigment epithelial cells occurs through a photooxidative mechanism and the resultant damage is hypothesized to induce or exacerbate age-related macular degeneration. The purpose of the present study was to identify changes in the cell growth and the expression of hepatocyte growth ...

journal_title：Photochemistry and photobiology

authors： Chu R,Zheng X,Chen D,Hu DN

更新日期：2006-09-01 00:00:00

abstract：:The photocycle in photoactive yellow protein (PYP) crystals was studied by single-crystal absorption spectroscopy with experimental setups for low-temperature and time-resolved measurements. Thin and flat PYP crystals, suitable for light absorption studies, were obtained using special crystallization conditions. Illum...

journal_title：Photochemistry and photobiology

authors： Kort R,Ravelli RB,Schotte F,Bourgeois D,Crielaard W,Hellingwerf KJ,Wulff M

更新日期：2003-08-01 00:00:00

abstract：:The photophysical parameters for the photosensitizer Pd(II) meso-Tetra(4-carboxyphenyl) porphine (PdT790) acquired in a previous study were incorporated into the PDT oxygen diffusion models for cell suspensions and cell monolayers. The time-dependent phosphorescence signals generated by the diffusion models are shown ...

journal_title：Photochemistry and photobiology

authors： Weston MA,Patterson MS

更新日期：2014-11-01 00:00:00

abstract：:The biguanide metformin is widely used for the treatment of Type-II diabetes. Its antiproliferative and pro-apoptotic effects in various tumor cells suggest its potential candidacy for cancer chemoprevention. Herein, we report that metformin significantly inhibited human epidermoid A431 tumor xenograft growth in nu/nu...

journal_title：Photochemistry and photobiology

authors： Chaudhary SC,Kurundkar D,Elmets CA,Kopelovich L,Athar M

更新日期：2012-09-01 00:00:00

abstract：:Reactive nitrogen species, produced during the process of inflammation induced by various factors including UV radiation, modify amino acids in crucial proteins. It is assumed that skin tissue is more likely to be modified, as it is located at the outer layer of a body that is exposed to UV radiation on a daily basis....

journal_title：Photochemistry and photobiology

authors： Ishitsuka Y,Maniwa F,Koide C,Douzaki N,Kato Y,Nakamura Y,Osawa T

更新日期：2007-05-01 00:00:00

abstract：:Chronic exposure of the gray, short-tailed oppossum, Monodelphis domestica to ultraviolet radiation (UVR) induces mesenchymal tumors of the cornea. High molecular weight DNA samples from 6 UVR-induced corneal tumors were assayed for their ability to transform NIH 3T3 cells to tumorigenicity. NIH 3T3 cells transfected ...

journal_title：Photochemistry and photobiology

authors： Sabourin CL,Freeman AG,Kusewitt DF,Ley RD

更新日期：1992-03-01 00:00:00

abstract：:Skin cancer studies depend on questionnaires to estimate exposure to ultraviolet light and subsequent risk but are limited by recall bias. We investigate the feasibility of developing a short checklist of categories comprising outdoor activities that can improve sun exposure questionnaires for use in epidemiologic stu...

journal_title：Photochemistry and photobiology

authors： Kwok RK,Linet MS,Chodick G,Kleinerman RA,Freedman DM,Fears T,Johnson RE,Alexander BH

更新日期：2009-01-01 00:00:00

abstract：:Unlike the enchanting yellow-green flashes of light produced on warm summer evenings by Photinus pyralis, the most common firefly species in North America, the orange lights of Photinus scintillans are infrequently observed. These Photinus species, and likely all bioluminescent beetles, use the same substrates beetle ...

journal_title：Photochemistry and photobiology

authors： Branchini BR,Southworth TL,Fontaine DM,Murtiashaw MH,McGurk A,Talukder MH,Qureshi R,Yetil D,Sundlov JA,Gulick AM

更新日期：2017-03-01 00:00:00

abstract：:Self-aggregation of naturally occurring bacteriochlorophyll (BChl)-e in nonpolar organic solvents was investigated by visible absorption, fluorescence emission and circular dichroism spectra. Cultured brown-colored photosynthetic bacteria have several BChl-e as light-harvesting antenna pigments. Three major BChl-e hom...

journal_title：Photochemistry and photobiology

authors： Saga Y,Matsuura K,Tamiaki H

更新日期：2001-07-01 00:00:00

abstract：:We investigated the effect of the cation-π interaction on the susceptibility of a tryptophan model system toward interaction with singlet oxygen, that is, type II photooxidation. The model system consists of two indole units linked to a lariat crown ether to measure the total rate of removal of singlet oxygen by the i...

journal_title：Photochemistry and photobiology

authors： Arevalo GE,Cagan DA,Monsour CG,Garcia AC,McCurdy A,Selke M

更新日期：2020-11-01 00:00:00

abstract：:The contribution of DNA strand breaks accumulating in the course of nucleotide excision repair to upregulation of the p53 tumor suppressor protein was investigated in human dermal fibroblast strains after treatment with 254 nm ultraviolet (UV) light. For this purpose, fibroblast cultures were exposed to UV and incubat...

journal_title：Photochemistry and photobiology

authors： Enns L,Murray D,Mirzayans R

更新日期：2000-10-01 00:00:00

abstract：:Photolysis of ester 1 in argon-saturated methanol and acetonitrile does not produce any product, whereas irradiation of 1 in oxygen-saturated methanol yields peroxide 2. Laser flash photolysis studies demonstrate that 1 undergoes intramolecular H atom abstraction to form biradical 3 (λmax ~340 nm), which intersystem c...

journal_title：Photochemistry and photobiology

authors： Das A,Lao EA,Gudmundsdottir AD

更新日期：2016-05-01 00:00:00

abstract：:Photodynamic treatment of promyelocytic K562 cells in the presence of a monoglucosylporphyrin or hematoporphyrin leads to a sequence of events recognized as hallmarks of apoptosis: a drop in mitochondrial potential, concurrent with a drop in ATP level and a decrease in cell respiration, translocation of phosphatidylse...

journal_title：Photochemistry and photobiology

authors： Carré V,Jayat C,Granet R,Krausz P,Guilloton M

更新日期：1999-01-01 00:00:00

abstract：:The photoprocesses of berberine, palmatine, coralyne, sanguinarine, flavopereirine and ellipticine were studied in several solvents. The quantum yields Φ(Δ) of singlet molecular oxygen formation of berberine, palmatine and sanguinarine are moderate in dichloromethane (0.2-0.6) and much smaller in acetonitrile or trifl...

journal_title：Photochemistry and photobiology

authors： Görner H,Miskolczy Z,Megyesi M,Biczók L

更新日期：2011-03-01 00:00:00

abstract：:DNA UVB dosimeters, consisting of minidots of dried bacteriophage DNA placed on a UV-transparent polymer film, were analyzed by polymerase chain reactions (PCR). Ultraviolet-B dosimetry obtained with amplification of phage lambda DNA of segments of 1.08 kilobase pairs (kbp) and 2.24 kbp was compared with that obtained...

journal_title：Photochemistry and photobiology

authors： Yoshida H,Regan JD

更新日期：1997-11-01 00:00:00

abstract：:The activity of the bimodal fluorescent protein (bmFP) (lambda max, 488 and 517 nm) in the in vitro luciferase reaction has been studied. The bmFP that is produced by Photobacterium phosphoreum strain bmFP is a dimer of two homologous subunits binding four riboflavin 5'-phosphate (FMN)-myristate chromophores. The addi...

journal_title：Photochemistry and photobiology

authors： Karatani H,Konaka T

更新日期：2000-02-01 00:00:00

abstract：:Syntheses for the new photosensitizers HOSiPcOSi(CH3)2(CH2)3N(CH1)1 or 3(CH3)2, Pc 34 and Pc 25, have been developed and the order of activity of these photosensitizers and the previously reported photosensitizer Pc 4, HOSiPcOSi(CH3)2(CH2)3N(CH3)2, in the dark and with broad-band red light toward Plasmodium falciparum...

journal_title：Photochemistry and photobiology

authors： Zhao XJ,Lustigman S,Li YS,Kenney ME,Ben-Hur E

更新日期：1997-08-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a way of treating malignant tumors and hyperproliferative diseases. It is based on the use of photosensitizer, herein the chlorophyll a (chl a), and a light of an appropriate wavelength. The interaction of the photosensitizer (PS) with the light produces reactive oxygen species (ROS), pow...

journal_title：Photochemistry and photobiology

authors： Cellamare BM,Fini P,Agostiano A,Sortino S,Cosma P

更新日期：2013-03-01 00:00:00

abstract：:Photodynamic therapy (PDT) of cancer induces oxidative stress, which intervenes in the expression of cytokines by tumor cells. The cytokines might have either a positive or a negative impact on tumor eradication. Here, we studied the expression of cytokines vascular endothelial growth factor (VEGF) and interleukin-1al...

journal_title：Photochemistry and photobiology

authors： Dabkeviciene D,Sasnauskiene A,Leman E,Kvietkauskaite R,Daugelaviciene N,Stankevicius V,Jurgelevicius V,Juodka B,Kirveliene V

更新日期：2012-03-01 00:00:00

abstract：:Excessive sun exposure can cause sunburn, suntan, skin photoaging, and even skin cancer. Skin photoaging conflicts with the human pursuit of a young and beautiful appearance. Some research data indicate that the incidence of skin cancer in the Chinese has been increasing, although it remains lower than in whites. To e...

journal_title：Photochemistry and photobiology

authors： Wan M,Hu R,Li Y,Wang Y,Xie X,Yue P,Guan L,Lai W

更新日期：2016-09-01 00:00:00

abstract：:The photochemistry of Ru(bpy)(3)+2 in the presence of amines was investigated in water by laser flash photolysis. N,N'-Dimethylaniline and p-phenylenediamine quench the luminescent metal to ligand charge transfer (MLCT) excited state of the complex by an electron transfer reaction that produces the semireduced form Ru...

journal_title：Photochemistry and photobiology

authors： Rivarola CR,Bertolotti SG,Previtali CM

更新日期：2006-01-01 00:00:00

abstract：:We previously reported that a low level of lysosomal photodamage potentiated the phototoxic effect of subsequent mitochondrial photodamage mediated by the benzoporphyrin derivative (BPD) in murine hepatoma 1c1c7 cells. This was attributed to release of Ca2+ from damaged lysosomes and a calpain-mediated conversion of t...

journal_title：Photochemistry and photobiology

authors： Kessel D,Reiners JJ Jr

更新日期：2017-11-01 00:00:00

abstract：:The total ozone column (TOC) is the most significant quantity for estimating the erythemally effective UV radiation under clear sky conditions. Uncertainties in TOC measurements and a limited spatial and temporal resolution therefore influence the quality of calculated erythemally effective radiation. The UV Index, th...

journal_title：Photochemistry and photobiology

authors： Schmalwieser AW,Erbertseder T,Schauberger G,Weihs P

更新日期：2008-09-01 00:00:00