Abstract:
OBJECTIVE:It has been suggested that adverse socioeconomic conditions "get under the skin" by eliciting a stress response that can trigger periodontal inflammation. We aimed to a) estimate the extent to which socioeconomic position (SEP) is associated with periodontal disease (PD) and proinflammatory oral immunity, and b) determine the contribution of psychosocial stress and stress hormones to these relationships. METHODS:In this cross-sectional study (n = 102), participants (20-59 years old) completed financial and perceived stress questionnaires and underwent full-mouth periodontal examinations. SEP was characterized by annual household income and educational attainment. Cortisol, a biological correlate of chronic stress, was assessed in hair samples. Oral immunity was characterized by assessing oral inflammatory load and proinflammatory oral neutrophil function. Blockwise Poisson and logistic regression models were applied. RESULTS:Compared with lower SEP, individuals in the middle- and higher-income categories had a significantly lower probability of PD (incidence rate ratio [IRR] = 0.5 [confidence interval {CI} = 0.3-0.7] and IRR = 0.4 [95% CI = 0.2-0.7]) and oral inflammatory load (IRR = 0.6 [95% CI = 0.3-0.8] and IRR = 0.5 [95% CI = 0.3-0.7]) and were less likely to have a proinflammatory oral immune function (odds ratio [OR] = 0.1 [95% CI = 0.0-0.7] and OR = 0.1 [95% CI = 0.0-0.9]). PD and oral immune parameters were significantly associated with financial stress and cortisol. Adjusting for financial stress and cortisol partially attenuated the socioeconomic differences in PD to IRR = 0.7 (95% CI = 0.5-0.8) and IRR = 0.6 (95% CI = 0.5-0.7) for the middle- and higher-income categories, respectively. Similar results were observed for proinflammatory immunity (OR = 0.2 [95% CI = 0.0-1.8] and OR = 0.3 [95% CI = 0.0-2.3]). CONCLUSION:These findings suggest that psychosocial stress may contribute to a proinflammatory immunity that is implicated in PD pathobiology and provide insight into social-to-biological processes in oral health.
journal_name
Psychosom Medjournal_title
Psychosomatic medicineauthors
Gomaa N,Glogauer M,Nicolau B,Tenenbaum H,Siddiqi A,Fine N,Quiñonez Cdoi
10.1097/PSY.0000000000000774subject
Has Abstractpub_date
2020-02-01 00:00:00pages
126-137issue
2eissn
0033-3174issn
1534-7796journal_volume
82pub_type
杂志文章abstract:OBJECTIVE:To study the sociocultural transformation of neurasthenia (shenjing shuairuo, SJSR), as both disease and illness, in Chinese society. METHOD:This is based on a critical review of evidence drawn from the psychiatric and anthropological literature, and the use of a single case study. RESULTS:SJSR remains a ub...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/00006842-199807000-00010
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:The objectives of this study were to test the hypothesis that high job demands and low job control (job strain) are associated with elevated free cortisol levels early in the working day and with reduced variability across the day and to evaluate the contribution of anger expression to this pattern. METHODS:...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200003000-00022
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:Depression in adults is associated with risk factors for cardiovascular disease (CVD). It is unclear, however, when the association between clinical depression and cardiac risk factors develops or how early in life this association can be detected. METHODS:In an ongoing study of pediatric depression, we comp...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000028
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:This study aimed to examine associations among race, the accumulation of multiple forms of discriminatory experiences (i.e., "pervasive discrimination"), and allostatic load (AL) in African Americans and whites in midlife. METHODS:Using data collected in 2004 to 2006 from 226 African American and 978 white a...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000788
更新日期:2020-04-01 00:00:00
abstract::The authors recruited 229 treatment-seeking anorexic and bulimic women for a prospective, longitudinal study. Telephone interviews were arranged every 3 months for at least 1 year for 225 patients. At intake, 132 subjects were menstruating, 34 subjects were taking oral contraceptives, 5 subjects had an organic cause f...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199503000-00004
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:To examine the association between the experience of daily interpersonal stress and levels of C-reactive protein (CRP), an inflammatory marker that is a key indicator of cardiovascular risk, during the teenage years. METHODS:A total of 69 adolescents (Mage= 17.78 years) completed daily diary checklists each ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181921b1f
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To test the reactivity hypothesis using blood pressure data collected 12 years after baseline. This study examined whether blood pressure reactions to acute mental stress predicted future blood pressure resting levels, as well as the temporal drift in resting blood pressure, and whether the prediction was aff...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182359808
更新日期:2011-11-01 00:00:00
abstract::This study was designed to investigate relationships between serum thyroid hormone levels and the severity of posttraumatic stress disorder (PTSD) symptoms in a group of 65 male Vietnam combat veterans who participated as members of cohorts in an elective inpatient treatment program. Thyroid hormone measures included ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-199507000-00012
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine whether enterotypes in the gut microbiome could be determined by clustering validity indexes and whether these enterotypes were associated with individual differences in temperament traits. METHODS:Sixty healthy Korean participants (21 men; 27.5 [8.1] years, 39 women;...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000459
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:The aging of the population implies that an increased number of people are going to need some form of care or assistance. Caregiving poses a range of physical, emotional, and financial demands and often causes burden and stress for family members. This article describes how technology can be used to provide s...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200205000-00011
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVE:Cardiovascular, neuroendocrine, and psychosocial profiles were investigated in women with eating disorder tendencies, but who had never met clinical criteria for an eating disorder, and in healthy controls. METHODS:Twenty-six women who scored in the highest distribution of the Eating Disorder Inventory bulim...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-200007000-00013
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVES:Research on the health of workers involved in the cleanup after the attack on the World Trade Center (WTC) on September 11, 2001, has documented high rates of psychological distress and upper gastrointestinal (GI) symptoms. The current article examines the concurrent and longitudinal associations of psycholo...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000116
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:Despite a well-documented association between stress and depression with cardiac morbidity and mortality, there is no satisfactory explanation for the mechanisms linking affective and cardiac disorders. This study investigated cardiac electrophysiological properties in an animal model of depression. METHODS:...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e318276cb0d
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To examine whether high-frequency heart rate variability, an indirect measure of parasympathetic (vagal) control over variations in heart rate, is associated with immune reactivity to an in vitro inflammatory challenge. Convergent evidence from the animal literature shows that the autonomic nervous system pla...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3181576118
更新日期:2007-11-01 00:00:00
abstract::Sixty women attending a family planning clinic completed assessments of their attributions for negative and positive mood states for an individual at different menstrual cycle stages. Negative moods occurring premenstrually were almost invariably viewed as related to health factors. Positive moods tended to be attribu...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198809000-00003
更新日期:1988-09-01 00:00:00
abstract:OBJECTIVE:Medically unexplained symptoms (MUS), which are highly prevalent in all fields of medicine, are considered difficult to treat. The primary objective of this systematic review and meta-analysis was to assess the efficacy of self-help for adults with MUS. METHODS:Four electronic databases were searched for rel...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/PSY.0000000000000325
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:Reexamine the claim that elderly Chinese-American women are able to prolong their lives until after the celebration of the Harvest Moon Festival. METHODS:See if independent 1985 to 2000 data for Chinese-, Korean-, and Vietnamese-Americans replicate results that were reported using 1960 to 1984 data for Chine...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000127875.38685.ba
更新日期:2004-05-01 00:00:00
abstract::This study examines patient outcomes up to seven years after a one-year, post-myocardial infarction (MI) stress monitoring and management program. A previous randomized controlled trial involving 461 male patients demonstrated that the program lowered stress scores and reduced one-year cardiac deaths by almost 50%, bu...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198909000-00002
更新日期:1989-09-01 00:00:00
abstract::Twelve subjects with specific phobias were exposed to slides with a phobic or a neutral content while cortisol excretion, electrodermal activity, and distress-ratings were studied. Six subjects fearful of blood and mutilation, and six of snakes or spiders, were presented with two sets of ten different slides (phobic o...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-198507000-00001
更新日期:1985-07-01 00:00:00
abstract:OBJECTIVE:Bipolar disorder (BD) is associated with elevated cardiovascular mortality rates. We investigated the modulation of l-arginine-nitric oxide (NO) signaling in platelets from patients with BD at different phases. METHODS:Platelets obtained from 28 patients with BD and 10 healthy volunteers were analyzed for l-...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e3182689460
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:The present investigation was designed to provide the first empirical examination of the effects of clonidine, a selective alpha 2-adrenergic agonist, on sexual arousal in women with and without prior sympathetic nervous system [SNS] stimulation by exercise. The purpose was to help elucidate the influence of ...
journal_title:Psychosomatic medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00006842-199707000-00010
更新日期:1997-07-01 00:00:00
abstract::In this article, we review the differences between momentary, retrospective, and trait self-report techniques and discuss the unique role that ambulatory reports of momentary experience play in psychosomatic medicine. After a brief historical review of self-report techniques, we discuss the latest perspective that lin...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,评审
doi:10.1097/PSY.0b013e3182546f18
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To examine individual differences in levels of emotional awareness as a predictor of the blood oxygenation level dependent (BOLD) response to trauma script-driven imagery in trauma-exposed individuals with (n = 25) and without (n = 16) posttraumatic stress disorder (PTSD). METHODS:Participants completed the ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0b013e31815f66d4
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To examine the potential moderating role of DRD2 polymorphism (rs1800497) in the association between stressful life events and depressive symptoms among young adults. Although stressful life events, such as divorce, unemployment, and serious illness in the family, are generally associated with negative health...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/psy.0b013e31806bf365
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the construct validity of the five-item Women's Health Initiative Insomnia Rating Scale (WHIIRS) by comparing women taking hormone therapy (HT) versus those taking a placebo and by comparing women known to differ in vasomotor symptoms. METHODS:The WHIIRS was includ...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/01.psy.0000151743.58067.f0
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:The aims of this pilot study were: 1) to establish the reliability and validity of a new self-report instrument designed to index monitoring for sleep-related threat; 2) to determine the presence of ten monitoring types proposed in a recent cognitive model of insomnia and to examine the relationship between m...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000114870.50968.90
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:Suboptimal self-care by individuals with diabetes mellitus (DM) is a significant public health concern. The common-sense model (CSM) proposes that illness representations are associated with coping and health outcomes across various conditions. The present study examined the efficacy of a CSM-based interventi...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/PSY.0000000000000883
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Major depressive disorder (MDD) is associated with more pain complaints and an altered pain perception. Studies regarding the longitudinal relationship between depressive symptoms and pain processing have rarely been performed and have produced inconsistent results. To clarify how short-term alleviation of de...
journal_title:Psychosomatic medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/PSY.0b013e31815c1b5d
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:The protective effects of female gender on the appearance and course of coronary heart disease (CHD) in nondiabetic subjects are diminished in the presence of diabetes. Depression predicts onset of and poor outcome from CHD in nondiabetic populations. We hypothesized that the doubled rates of depression in fe...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/01.psy.0000041624.96580.1f
更新日期:2003-05-01 00:00:00
abstract::The peripheral decarboxylase inhibitor carbidopa (L-alphamethyl-dopa-hydrazine) allowed safe intravenous administration of L-DOPA in amounts sufficient to alter cortical average evoked response (AER) and learning function in 13 depressed patients. The apparently rapid conversion of L-DOPA to dopamine, as reported from...
journal_title:Psychosomatic medicine
pub_type: 杂志文章
doi:10.1097/00006842-197603000-00003
更新日期:1976-03-01 00:00:00