The Association Between Temperament and Microbiota in Healthy Individuals: A Pilot Study.

Abstract:

OBJECTIVE:The purpose of this study was to examine whether enterotypes in the gut microbiome could be determined by clustering validity indexes and whether these enterotypes were associated with individual differences in temperament traits. METHODS:Sixty healthy Korean participants (21 men; 27.5 [8.1] years, 39 women; 34.5 [14.3] years) were asked to answer 60 temperament questions (novelty seeking, harm avoidance, reward dependence, and persistence) from the Korean version of the Temperament and Character Inventory-125. The participants' stool samples were submitted, and relative operational taxonomic units were calculated using 16S rRNA gene-based microarrays. Differences between sexes and age-related effects on the temperament and operational taxonomic unit abundances were determined, and optimal clustering numbers related to enterotypes were examined using connectivity and silhouette width (SW) indexes. Finally, the differences in temperament between enterotypes were examined. RESULTS:There was no significant effect of sex or age on gut microbiota and temperament scores. The hierarchical dendrogram, connectivity, and SW analysis indicated bimodal enterotypes. Bacteroidaceae were more abundant in enterotype 1 (46.24%, N = 45), whereas Prevotellaceae were more abundant in enterotype 2 (43.83%, n = 15). Among the four temperament dimensions, novelty seeking and reward dependence scores were higher in enterotype 1 (10.82 [2.99] and 8.07 [2.51] points) than in enterotype 2 (8.87 [2.42] and 5.73 [1.03] points). CONCLUSIONS:The results suggest an association between temperament and enterotypes in healthy Korean adults. It is conceivable that this association may develop early in life as a result of biological processes catalyzed by the gut microbiota during infancy.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

Kim H,Park YJ

doi

10.1097/PSY.0000000000000459

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

898-904

issue

8

eissn

0033-3174

issn

1534-7796

journal_volume

79

pub_type

杂志文章
  • Women with eating disorder tendencies display altered cardiovascular, neuroendocrine, and psychosocial profiles.

    abstract:OBJECTIVE:Cardiovascular, neuroendocrine, and psychosocial profiles were investigated in women with eating disorder tendencies, but who had never met clinical criteria for an eating disorder, and in healthy controls. METHODS:Twenty-six women who scored in the highest distribution of the Eating Disorder Inventory bulim...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200007000-00013

    authors: Koo-Loeb JH,Costello N,Light KC,Girdler SS

    更新日期:2000-07-01 00:00:00

  • Hostility, gender, and cardiac autonomic control.

    abstract:OBJECTIVE:Although considerable evidence implicates hostility in the development of coronary artery disease (CAD), the pathogenic mechanisms remain poorly understood. We have developed a psychophysiological model that holds that altered autonomic nervous system function links psychological traits with CAD outcomes. In ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200105000-00012

    authors: Sloan RP,Bagiella E,Shapiro PA,Kuhl JP,Chernikhova D,Berg J,Myers MM

    更新日期:2001-05-01 00:00:00

  • Psychological stress, cytokine production, and severity of upper respiratory illness.

    abstract:OBJECTIVE:The purpose of this study is to assess the role of psychological stress in the expression of illness among infected subjects and to test the plausibility of local proinflammatory cytokine production as a pathway linking stress to illness. METHODS:After completing a measure of psychological stress, 55 subject...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199903000-00009

    authors: Cohen S,Doyle WJ,Skoner DP

    更新日期:1999-03-01 00:00:00

  • Influence of a "warm touch" support enhancement intervention among married couples on ambulatory blood pressure, oxytocin, alpha amylase, and cortisol.

    abstract:OBJECTIVE:To investigate whether a support intervention (warm touch enhancement) influences physiological stress systems that are linked to important health outcomes. Growing evidence points to a protective effect of social and emotional support on both morbidity and mortality. METHODS:In this study, 34 healthy marrie...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0b013e318187aef7

    authors: Holt-Lunstad J,Birmingham WA,Light KC

    更新日期:2008-11-01 00:00:00

  • Cardiovascular-emotional dampening: the relationship between blood pressure and recognition of emotion.

    abstract:OBJECTIVE:Persons with elevated blood pressure (BP) show dampened emotional responses to affect-laden stimuli. We sought to further examine cardiovascular-emotional dampening by examination of the relationship between resting hemodynamic measures and recognition of emotion in an African American community-based sample....

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e318235ed55

    authors: McCubbin JA,Merritt MM,Sollers JJ 3rd,Evans MK,Zonderman AB,Lane RD,Thayer JF

    更新日期:2011-11-01 00:00:00

  • Childhood Bullying Victimization and Overweight in Young Adulthood: A Cohort Study.

    abstract:OBJECTIVE:To test whether bullied children have an elevated risk of being overweight in young adulthood and whether this association is: (1) consistent with a dose-response relationship, namely, its strength increases with the chronicity of victimization; (2) consistent across different measures of overweight; (3) spec...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000388

    authors: Baldwin JR,Arseneault L,Odgers C,Belsky DW,Matthews T,Ambler A,Caspi A,Moffitt TE,Danese A

    更新日期:2016-11-01 00:00:00

  • Adjustment in diabetic adolescent girls: II. Adjustment, self-esteem, and depression in diabetic adolescent girls.

    abstract::The Rosenberg Self-Esteem Scale, Beck Depression Inventory, and Sullivan Diabetic Adjustment Scale were administered to 105 adolescent girls with diabetes. Results indicate that levels of self-esteem and depression highly correlate with the level of adjustment as assessed on the Diabetic Adjustment Scale (DAS). That i...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197903000-00006

    authors: Sullivan BJ

    更新日期:1979-03-01 00:00:00

  • Association of depressive and anxiety symptoms with 24-hour urinary catecholamines in individuals with untreated high blood pressure.

    abstract:OBJECTIVE:Depression and anxiety are considered risk factors for cardiovascular disease (CVD). The explanatory mechanisms, however, are still to be characterized. One proposed pathophysiological pathway is dysregulation of the autonomic nervous system, including heightened sympathetic nervous system activity. This stud...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000144

    authors: Paine NJ,Watkins LL,Blumenthal JA,Kuhn CM,Sherwood A

    更新日期:2015-02-01 00:00:00

  • Social competence interview for assessing physiological reactivity in adolescents.

    abstract::Difficulties in predicting "real life" physiological variation from responses to controlled stress tasks suggest the need for more ecologically valid laboratory challenges. The Social Competence Interview (SCI) measures physiological changes elicited by re-experiencing a life situation in which a valued striving was u...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199105000-00003

    authors: Ewart CK,Kolodner KB

    更新日期:1991-05-01 00:00:00

  • Waist-to-hip ratio is positively associated with bioavailable testosterone but negatively associated with sexual desire in healthy premenopausal women.

    abstract:OBJECTIVE:We examined whether high waist-to-hip ratio (WHR) in women is a biomarker for increased testosterone (T) and higher levels of sexual desire. METHODS:Participants were 99 healthy nonobese premenopausal women. Trait levels of mean bioavailable T were estimated from three saliva samples collected at 8:00 am, 9:...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000151747.22904.d7

    authors: van Anders SM,Hampson E

    更新日期:2005-03-01 00:00:00

  • Cardiovascular Risk Factors as Differential Predictors of Incident Atypical and Typical Major Depressive Disorder in US Adults.

    abstract:OBJECTIVE:Although the association between major depressive disorder (MDD) and future cardiovascular disease (CVD) is established, less is known about the relationship between CVD risk factors and future depression, and no studies have examined MDD subtypes. Our objective was to determine whether hypertension, tobacco ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000583

    authors: Patel JS,Berntson J,Polanka BM,Stewart JC

    更新日期:2018-07-01 00:00:00

  • Understanding the Gut Microbiota in Inflammatory and Functional Gastrointestinal Diseases.

    abstract:OBJECTIVE:During the last decade, experimental and observational studies have shown that patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) may have an altered intestinal microbial composition compared with healthy individuals. However, no uniform microbial signature has as yet been detec...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/PSY.0000000000000470

    authors: Sundin J,Öhman L,Simrén M

    更新日期:2017-10-01 00:00:00

  • Depressive symptom clusters as predictors of 6-year increases in insulin resistance: data from the Pittsburgh Healthy Heart Project.

    abstract:OBJECTIVE:To examine longitudinal bidirectional associations between two depressive symptom clusters-the cognitive-affective and somatic-vegetative clusters--and insulin resistance, a marker of prediabetes. METHODS:Participants were 269 adults aged 50 to 70 years without diabetes enrolled in the Pittsburgh Healthy Hea...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000063

    authors: Khambaty T,Stewart JC,Muldoon MF,Kamarck TW

    更新日期:2014-06-01 00:00:00

  • Serotonergic changes in specific areas of rat brain associated with activity--stress gastric lesions.

    abstract::To study serotonergic involvement in the development of gastric lesions following activity wheel stress, three groups of rats (gastric lesions, no gastric lesions, and home--cage controls) were killed following exposure to the experimental procedures. The brains were dissected into eight specific areas and subjected t...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198305000-00004

    authors: Hellhammer DH,Hingtgen JN,Wade SE,Shea PA,Aprison MH

    更新日期:1983-05-01 00:00:00

  • Rumination predicts longer sleep onset latency after an acute psychosocial stressor.

    abstract:OBJECTIVES:Rumination has been linked to self-reported sleep quality. However, whether rumination is related to an objective sleep parameter has not been tested. This study examined whether rumination predicts sleep onset latency (SOL) on the night after an acute psychosocial stressor. We hypothesized that those who ru...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181ae58e8

    authors: Zoccola PM,Dickerson SS,Lam S

    更新日期:2009-09-01 00:00:00

  • Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesity.

    abstract:OBJECTIVE:A role for the brain-derived neurotrophic factor (BDNF) in the regulation of eating behavior has been recently demonstrated. Therefore, the possibility exists that alterations in BDNF production and/or activity are involved in the pathophysiology of anorexia nervosa (AN) and obesity. METHODS:We measured morn...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000138119.12956.99

    authors: Monteleone P,Tortorella A,Martiadis V,Serritella C,Fuschino A,Maj M

    更新日期:2004-09-01 00:00:00

  • Atypical sexual behavior during sleep.

    abstract:OBJECTIVE:This article reports a case series of atypical sexual behavior during sleep, which is often harmful to patients or bed partners. METHODS:Eleven subjects underwent clinical evaluation of complaints of sleep-related atypical sexual behavior. Complaints included violent masturbation, sexual assaults, and contin...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-200203000-00017

    authors: Guilleminault C,Moscovitch A,Yuen K,Poyares D

    更新日期:2002-03-01 00:00:00

  • Depression and smoking in coronary heart disease.

    abstract:OBJECTIVE:This review examines the relationship between depression and smoking in coronary heart disease (CHD). It summarizes relevant findings from general population and smoking cessation studies and discusses the few studies that have investigated whether smoking confounds, mediates, or moderates the effect of depre...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/01.psy.0000162255.55629.9c

    authors: Freedland KE,Carney RM,Skala JA

    更新日期:2005-05-01 00:00:00

  • The Role of Hippocampal Functional Connectivity on Multisystem Subclinical Abnormalities in Schizophrenia.

    abstract:OBJECTIVE:Schizophrenia is associated with excess medical mortality: patients have an average life expectancy one to two decades shorter than the general population. This study investigates the relationship between aberrant hippocampal resting-state functional connectivity in schizophrenia and cumulative subclinical ef...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000813

    authors: Hare SM,Chiappelli J,Savransky A,Adhikari BM,Wisner K,Kvarta M,Goldwaser E,Du X,Chen S,Rowland LM,Kochunov P,Hong LE

    更新日期:2020-07-01 00:00:00

  • Patterning of cognitive and somatic processes in the self-regulation of anxiety: effects of meditation versus exercise.

    abstract::Davidson and Schwartz (1) have proposed a psychobiological analysis of anxiety that emphasizes the patterning of multiple processes in the generation and self-regulation of this state. The present article specifically reviews recent research on cognitive and somatic components of anxiety. A dual component scale which ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197806000-00004

    authors: Schwartz GE,Davidson RJ,Goleman DJ

    更新日期:1978-06-01 00:00:00

  • Diagnostic groups and depressed mood as predictors of 22-month mortality in medical inpatients.

    abstract:OBJECTIVE:While depression has been found to predict mortality in acute myocardial infarction, results from many other groups of medical patients are inconclusive. It is, therefore, unclear whether depression also predicts mortality in the typical mixed patient populations treated on medical hospital wards and whether ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199809000-00011

    authors: Herrmann C,Brand-Driehorst S,Kaminsky B,Leibing E,Staats H,Rüger U

    更新日期:1998-09-01 00:00:00

  • Childhood Cognitive Ability and Age-Related Changes in Physical Capability From Midlife: Findings From a British Birth Cohort Study.

    abstract:OBJECTIVE:The aim of the study was to test the hypothesis that higher childhood cognitive ability is associated with reduced risk of decline in physical capability in late midlife. METHODS:Participants were 1954 men and women from the Medical Research Council National Survey of Health and Development with complete dat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000482

    authors: Cooper R,Richards M,Kuh D

    更新日期:2017-09-01 00:00:00

  • Defective nitric oxide-cyclic guanosine monophosphate signaling in patients with bipolar disorder: a potential role for platelet dysfunction.

    abstract:OBJECTIVE:Bipolar disorder (BD) is associated with elevated cardiovascular mortality rates. We investigated the modulation of l-arginine-nitric oxide (NO) signaling in platelets from patients with BD at different phases. METHODS:Platelets obtained from 28 patients with BD and 10 healthy volunteers were analyzed for l-...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182689460

    authors: Fontoura PC,Pinto VL,Matsuura C,Resende Ade C,de Bem GF,Ferraz MR,Cheniaux E,Brunini TM,Mendes-Ribeiro AC

    更新日期:2012-10-01 00:00:00

  • Decreased bone mineral density in medicated psychiatric patients.

    abstract::Osteoporosis is a common problem in postmenopausal women. It has been linked to estrogen deficiency, other neuroendocrine processes such as hypercortisolemia and male hypogonadism, nutritional deficiencies, and other mechanisms. Some of these changes have been also reported in male and female patients with mental diso...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199509000-00011

    authors: Halbreich U,Rojansky N,Palter S,Hreshchyshyn M,Kreeger J,Bakhai Y,Rosan R

    更新日期:1995-09-01 00:00:00

  • Evidence of early retinal microvascular changes in patients with type 2 diabetes and depression.

    abstract:OBJECTIVE:To examine retinal vascular caliber, an indicator of early microvascular disease and depression in patients with Type 2 diabetes. METHODS:We conducted a clinic-based study, comparing participants with Type 2 diabetes with major depression (n = 43), without depression (n = 49), and healthy controls without di...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181da90f4

    authors: Nguyen TT,Wong TY,Islam FM,Hubbard L,Ajilore O,Haroon E,Darwin C,Esser B,Kumar A

    更新日期:2010-07-01 00:00:00

  • Sleep disorder and psychobiological symptomatology in male psychiatric outpatients and male nonpatients.

    abstract::Sleep disturbance was studied in relation to psychiatric and physical symptoms for 214 male psychiatric outpatients and 248 male nonpatients. Our self-report instrument required that subjects describe the frequency of symptoms precisely on a five-point scale from "every day" to "not at all." Percentages are based on t...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197611000-00002

    authors: Sweetwood HL,Kripke DF,Grant I,Yager J,Gerst MS

    更新日期:1976-11-01 00:00:00

  • The Cook-Medley hostility scale: item content and ability to predict survival.

    abstract::Previous studies have identified the MMPI-based Cook and Medley hostility scale (Ho) as a predictor of health outcomes. To achieve a better understanding of the construct measured by this scale, Ho items were classified on an a priori basis. Six subsets were identified: Cynicism, Hostile Attributions, Hostile Affect, ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198901000-00005

    authors: Barefoot JC,Dodge KA,Peterson BL,Dahlstrom WG,Williams RB Jr

    更新日期:1989-01-01 00:00:00

  • Cortisol excretion during the defense reaction in humans.

    abstract::Twelve subjects with specific phobias were exposed to slides with a phobic or a neutral content while cortisol excretion, electrodermal activity, and distress-ratings were studied. Six subjects fearful of blood and mutilation, and six of snakes or spiders, were presented with two sets of ten different slides (phobic o...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198507000-00001

    authors: Fredrikson M,Sundin O,Frankenhaeuser M

    更新日期:1985-07-01 00:00:00

  • Parental history of hypertension and coping responses predict blood pressure changes in black college volunteers undergoing a speaking task about perceptions of racism.

    abstract:OBJECTIVE:This investigation explored the relationship of coping responses and parental history of hypertension to task-induced blood pressure changes. MATERIALS AND METHODS:The sample consisted of 215 black college student volunteers (median age = 25.95 y). During the speaking task, participants responded to standard...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000097331.10458.f1

    authors: Clark R

    更新日期:2003-11-01 00:00:00

  • Nighttime heart rate and survival in depressed patients post acute myocardial infarction.

    abstract:OBJECTIVES:To determine if: 1) depressed patients with a recent acute myocardial infarction (AMI) have higher nighttime heart rate (HR) than nondepressed patients, and 2) elevated nighttime HR is associated with decreased survival post AMI. Depression is a risk factor for mortality post AMI. It is also associated with ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181835ca3

    authors: Carney RM,Steinmeyer B,Freedland KE,Blumenthal JA,Stein PK,Steinhoff WA,Howells WB,Berkman LF,Watkins LL,Czajkowski SM,Domitrovich PP,Burg MM,Hayano J,Jaffe AS

    更新日期:2008-09-01 00:00:00