Ultrasound/Optical Dual-Modality Imaging for Evaluation of Vulnerable Atherosclerotic Plaques with Osteopontin Targeted Nanoparticles.

abstract：:The unicellular cyanobacterium Cyanothece sp. CCY 0110 is a highly efficient producer of extracellular polymeric substances (EPS), releasing up to 75% of the polymer to the culture medium. The carbohydrate polymer released to the medium (RPS) was previously isolated and characterized; it is composed of nine different ...

journal_title：Macromolecular bioscience

authors： Leite JP,Mota R,Durão J,Neves SC,Barrias CC,Tamagnini P,Gales L

更新日期：2017-02-01 00:00:00

abstract：:A CMB monomer was polymerized on a glass plate with a surface-confined ATRP initiator containing a 2-bromoisobutyryl group. The glass plate modified with a PCMB brush was highly hydrophilic and showed a strong resistance against non-specific adsorption of proteins and cell adhesion. Upon ion beam irradiation, furtherm...

journal_title：Macromolecular bioscience

authors： Kitano H,Suzuki H,Kondo T,Sasaki K,Iwanaga S,Nakamura M,Ohno K,Saruwatari Y

更新日期：2011-04-08 00:00:00

abstract：:Biodegradable hydrogels were synthesized by the click reaction of 4-arm azido-terminated PEG differing in molecular weight (2,100 and 8,800) and two alkyne-terminated peptides: [alkyne]-GFLGK-[alkyne] and ([alkyne]-GFLG)(2)K. The physical properties of in situ formed hydrogels were examined. The hydrogels were highly ...

journal_title：Macromolecular bioscience

authors： Yang J,Jacobsen MT,Pan H,Kopecek J

更新日期：2010-04-08 00:00:00

abstract：:Although recently a growing number of reports demonstrate that topography or geometry of the substrate also plays an important role in the fate of the stem cells, most of these studies are usually completed by a few distinct patterns such as simple lines, posts, etc. As a result, there is a lack of quantitative analys...

journal_title：Macromolecular bioscience

authors： Seo CH,Furukawa K,Suzuki Y,Kasagi N,Ichiki T,Ushida T

更新日期：2011-07-07 00:00:00

abstract：:Novel temperature-sensitive poly(N-isopropylacrylamide)/amine-terminated polyamidoamine dendrimer G6-NH2 hydrogels with fast responsive properties were synthesized by forming semi-interpenetrating polymeric networks. In contrast to the conventional PNIPA hydrogel, these new gels showed rapid shrinking rate at the temp...

journal_title：Macromolecular bioscience

authors： Zhang JT,Huang SW,Zhuo RX

更新日期：2004-06-25 00:00:00

abstract：:Different strategies of chemotherapeutics-based combination cancer therapy have presented enhanced antitumor efficiency and are widely used in clinical cancer treatments. However, several drawbacks of the systems for systemic administration, including low drug accumulation at tumor sites and significant systemic side ...

journal_title：Macromolecular bioscience

authors： Yu S,He C,Chen X

更新日期：2018-12-01 00:00:00

abstract：:Hydroxypropyl chitosan-graft-carboxymethyl beta-cyclodextrin (HPCH-g-CM beta-CD) was synthesized by grafting CM beta-CD onto HPCH using water soluble 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) as the condensing agent. Due to the presence of hydrophobic beta-CD rings onto the HPCH backbone, this polymer can be...

journal_title：Macromolecular bioscience

authors： Prabaharan M,Mano JF

更新日期：2005-10-20 00:00:00

abstract：:Aggregation of denatured or unfolded proteins establishes a large energy barrier to spontaneous recovery of protein form and function following traumatic injury, tissue cryopreservation, and biopharmaceutical storage. Some tissues utilize small heat shock proteins (sHSPs) to prevent irreversible aggregation, which all...

journal_title：Macromolecular bioscience

authors： Poellmann MJ,Sosnick TR,Meredith SC,Lee RC

更新日期：2017-02-01 00:00:00

abstract：:The material surface must be considered in the design of scaffolds for bone tissue engineering so that it supports bone cells adhesion, proliferation and differentiation. A biomimetic approach has been developed as a 3D surface modification technique to grow partially carbonated hydroxyapatite (the bonelike mineral) i...

journal_title：Macromolecular bioscience

authors： Zhang R,Ma PX

更新日期：2004-02-20 00:00:00

abstract：:Peptide dendrimers assembled by solid-phase peptide synthesis using a branching diamino acid at every 2(nd) or 3(rd) position provide readily accessible synthetic model systems for proteins and enzymes. They adopt a globular shape by topology rather than by folding. Peptide dendrimers of 2(nd) and 3(rd) generation fun...

journal_title：Macromolecular bioscience

authors： Delort E,Szöcs E,Widmer R,Siegenthaler H,Reymond JL

更新日期：2007-08-07 00:00:00

abstract：:In pluripotent stem cell differentiation, embryoid bodies (EBs) provide a three-dimensional [3D] multicellular precursor in lineage specification. The internal structure of EBs is not well characterized yet is predicted to be an important parameter to differentiation. Here, we use custom SU-8 molds to generate transpa...

journal_title：Macromolecular bioscience

authors： Tomov ML,Olmsted ZT,Paluh JL

更新日期：2015-07-01 00:00:00

abstract：:A combination of hard sphere and high internal phase emulsion templating gives a platform for synthesizing hierarchically porous polymers with a unique topology exhibiting interconnected spherical features on multiple levels. Polymeric spheres are fused by thermal sintering to create a 3D monolithic structure while an...

journal_title：Macromolecular bioscience

authors： Paljevac M,Gradišnik L,Lipovšek S,Maver U,Kotek J,Krajnc P

更新日期：2018-02-01 00:00:00

abstract：:Emphasizing the role of hydrogel stiffness and cellular differentiation, this study develops collagen and elastin-like polypeptide (ELP)-based bone regenerative hydrogels loaded with recombinant human bone morphogenetic protein-2 (rhBMP-2) and doxycycline with mechanical properties suitable for osteogenesis. The drug-...

journal_title：Macromolecular bioscience

authors： Pal P,Nguyen QC,Benton AH,Marquart ME,Janorkar AV

更新日期：2019-09-01 00:00:00

abstract：:Plant derived flavonoids have not been well explored in tissue engineering applications due to difficulties in efficient formulations with biomaterials for controlled presentation. Here, the authors report that surface coating of epigallocatechin gallate (EGCG) on polymeric substrates including poly (L-lactic acid) (P...

journal_title：Macromolecular bioscience

authors： Madhurakkat Perikamana SK,Lee SM,Lee J,Ahmad T,Lee MS,Yang HS,Shin H

更新日期：2019-04-01 00:00:00

abstract：:Well-defined amphiphilic polymers of the ABA and ABC type are synthesized, where A is poly(L-lysine hydrochloride) (PLL), B is poly(γ-benzyl-(d7) L-glutamate) (PBLG(-d7)), and C is poly(ethylene oxide) (PEO). The two polymers exhibit similar PBLG(-d7) composition, while in the ABC, the volume fraction of PEO block is ...

journal_title：Macromolecular bioscience

authors： Iatrou H,Dimas K,Gkikas M,Tsimblouli C,Sofianopoulou S

更新日期：2014-09-01 00:00:00

abstract：:Recombinantly produced spider silk proteins have high potential for bioengineering and various biomedical applications because of their biocompatibility, biodegradability, and low immunogenicity. Here, the recently described small spider silk protein eMaSp1s is assembled into hydrogels, which can be 3D printed into sc...

journal_title：Macromolecular bioscience

authors： Thamm C,DeSimone E,Scheibel T

更新日期：2017-11-01 00:00:00

abstract：:Two different composite scaffolds, solid-freeform-fabricated PCL/β-TCP supplemented with and without collagen nanofibers are fabricated. These scaffolds are evaluated whether a combination of collagen nanofibers with PCL/β-TCP can promote osteogenesis in a mastoid obliteration. To assess the effects of the cellular ac...

journal_title：Macromolecular bioscience

authors： Jang CH,Cho YB,Yeo MG,Kim GH

更新日期：2013-05-01 00:00:00

abstract：:Branched polyethylenimine (25 kDa) is thiolated and compared with redox-sensitive crosslinked derivatives. Both polymers thiol contents are assessed; the thiolated polymers have 390-2300 mmol SH groups/mol, whereas the crosslinked polymers have lower thiol contents. Cytotoxicity assays show that both modified polymers...

journal_title：Macromolecular bioscience

authors： Aravindan L,Bicknell KA,Brooks G,Khutoryanskiy VV,Williams AC

更新日期：2013-09-01 00:00:00

abstract：:Given the major structural role phosphodiesters play in the organism it is surprising they have not been more widely adopted as a building block in sophisticated biomimetic hydrogels and other biomaterials. The potential benefits are substantial: phosphoester-based materials show excellent compatibility with blood, ce...

journal_title：Macromolecular bioscience

authors： Dera R,Diliën H,Billen B,Gagliardi M,Rahimi N,Van Den Akker NMS,Molin DGM,Grandfils C,Adriaensens P,Guedens W,Cleij TJ

更新日期：2019-07-01 00:00:00

abstract：:A tissue-engineering scaffold resembling the structure of the natural extracellular matrix can often facilitate tissue regeneration. Nerve and tendon are oriented micro-scale tissue bundles. In this study, a method combining injection molding and thermally induced phase separation techniques is developed to create sin...

journal_title：Macromolecular bioscience

authors： Sun C,Jin X,Holzwarth JM,Liu X,Hu J,Gupte MJ,Zhao Y,Ma PX

更新日期：2012-06-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is an important protein for wound healing and angiogenesis in tissue engineering, but the lack of a viable delivery system hampers its clinical application. This study aims to maintain the long-term controlled release of bFGF by utilizing a collagen/heparin bi-affinity multilayer ...

journal_title：Macromolecular bioscience

authors： Hao W,Han J,Chu Y,Huang L,Zhuang Y,Sun J,Li X,Zhao Y,Chen Y,Dai J

更新日期：2018-11-01 00:00:00

abstract：:Polymers such as poly(N-vinyl-2-pyrrolidone) (PVP) have been used to prepare hydrogels for wound dressing applications but are not inherently bioactive. For enhanced healing, PVP was blended with salicylic acid-based poly(anhydride-esters) (SAPAE) and shown to exhibit hydrogel properties upon swelling. In vitro releas...

journal_title：Macromolecular bioscience

authors： Ouimet MA,Fogaça R,Snyder SS,Sathaye S,Catalani LH,Pochan DJ,Uhrich KE

更新日期：2015-03-01 00:00:00

abstract：:The use of glycopolymer-functionalized resins (Resin-Glc), as a solid support, in column mode for bacterial/protein capture and quantification is explored. The Resin-Glc is synthesized from commercially available chloromethylated polystyrene resin and glycopolymer, and is characterized by fourier transform infrared sp...

journal_title：Macromolecular bioscience

authors： Ajish JK,Abraham HM,Subramanian M,Kumar KSA

更新日期：2020-12-18 00:00:00

abstract：:In drug delivery to the human brain, blood vessels are a significant hurdle because they restrict the entry of most solutes to protect brain. To overcome this hurdle, an in vitro 3D model for brain endothelial barrier is developed using a microfluidic device with hydrogel providing a 3D extracellular matrix scaffold. ...

journal_title：Macromolecular bioscience

authors： Chung B,Kim J,Nam J,Kim H,Jeong Y,Liu HW,Cho Y,Kim YH,Oh HJ,Chung S

更新日期：2020-06-01 00:00:00

abstract：:Amino acid ester substituted polyphosphazenes are osteoactive benefiting from their phosphorus-containing chemical structure, which highlights interests in bone tissue engineering. To correlate their chemical structures with cell activities, in this study, poly[(ethyl alanato)0.3 (ethyl glycinato)0.7 phosphazene] (PAG...

journal_title：Macromolecular bioscience

authors： Huang Z,Yang L,Hu X,Huang Y,Cai Q,Ao Y,Yang X

更新日期：2019-06-01 00:00:00

abstract：:Solution-grown chain-folded lamellar single crystals of poly(tetramethylene adipate) (PTMA) were prepared from a dilute solution of 2-methyl-1-propanol by isothermal crystallization. PTMA crystals were hexagonal-shaped and polyethylene decoration of the crystals resulted in a "six cross-sector" surface morphology and ...

journal_title：Macromolecular bioscience

authors： Iwata T,Kobayashi S,Tabata K,Yonezawa N,Doi Y

更新日期：2004-03-15 00:00:00

abstract：:Artificial ECMs that not only closely mimic the hybrid nature of the natural ECM but also provide tunable material properties and enhanced biological functions are attractive candidates for tissue engineering applications. This review summarizes recent advances in developing multicomponent hybrid hydrogels by integrat...

journal_title：Macromolecular bioscience

authors： Jia X,Kiick KL

更新日期：2009-02-11 00:00:00

abstract：:Several high-resolution imaging techniques such as FESEM, TEM and AFM are compared with respect to their application on alginate hydrogels, a widely used polysaccharide biomaterial. A new AFM method applicable to RGD peptides covalently conjugated to alginate hydrogels is described. High-resolution images of RGD adhes...

journal_title：Macromolecular bioscience

authors： Hsiong SX,Cooke PH,Kong HJ,Fishman ML,Ericsson M,Mooney DJ

更新日期：2008-06-11 00:00:00

abstract：:Since the early 1980s, research on the modification of bone implant surfaces by applying coatings has mainly focused on the application of inorganic calcium phosphate (CaP) coatings using physical deposition techniques. Organic components of the extracellular bone matrix, on the other hand, play an essential role in t...

journal_title：Macromolecular bioscience

authors： Nijhuis AW,Leeuwenburgh SC,Jansen JA

更新日期：2010-11-10 00:00:00

abstract：:Within this work, a new class of sequence-defined heteromultivalent glycomacromolecules bearing lactose residues and nonglycosidic motifs for probing glycoconjugate recognition in carbohydrate recognition domain (CRD) of galectin-3 is presented. Galectins, a family of β-galactoside-binding proteins, are known to play ...

journal_title：Macromolecular bioscience

authors： Freichel T,Heine V,Laaf D,Mackintosh EE,Sarafova S,Elling L,Snyder NL,Hartmann L

更新日期：2020-09-01 00:00:00