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EUCAST recommendations for antimicrobial susceptibility testing applied to the three main Campylobacter species isolated in humans.

Abstract：

:Antimicrobial susceptibility testing of Campylobacter isolates is of great importance for treatment options especially in systemic diseases. The European Committee for Antimicrobial Susceptibility Testing (EUCAST) recently proposed epidemiological cut-offs (ECOFFs) for a limited number of antimicrobial compounds and for Campylobacter jejuni and Campylobacter coli only. In the present study, the EUCAST method was used after minor modifications to define antimicrobial susceptibility patterns for, 1997 C. jejuni, 419 C. coli and 100 Campylobacter fetus strains received at the French National Reference Center for Campylobacters and Helicobacters. Our results show that the ECOFFs defined by EUCAST for tetracycline and ciprofloxacin can be used for C. jejuni and C. coli. The same ECOFF can be used for erythromycin for the three species. The C. jejuni and C. coli ECOFFs for ciprofloxacin however cannot be applied to C. fetus. We also provide data to categorise two 2 β-lactams of interest for systemic diseases, ampicillin and amoxicillin+clavulanate, for the three species.

journal_name

J Microbiol Methods

journal_title

Journal of microbiological methods

authors

Sifré E,Salha BA,Ducournau A,Floch P,Chardon H,Mégraud F,Lehours P

doi

10.1016/j.mimet.2015.10.018

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

206-13

eissn

0167-7012

issn

1872-8359

pii

S0167-7012(15)30096-8

journal_volume

119

pub_type

杂志文章

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