Metagenomic analysis of bronchoalveolar lavage samples from patients with idiopathic interstitial pneumonia and its antagonic relation with Pneumocystis jirovecii colonization.

Abstract:

:Idiopathic interstitial pneumonias are interstitial lung diseases of unknown etiology which prognosis is usually fatal. Microbiota associated to bronchoalveolar lavage from 20 patients with negative bacterial cultures was explored by 16S-rDNA PCR-DGGE, showing a clearly negative relation among the presence of P. jirovecii and bacterial colonization. This is the first report of in vivo antagonistic relation among fungi and bacteria.

journal_name

J Microbiol Methods

authors

Friaza V,la Horra Cd,Rodríguez-Domínguez MJ,Martín-Juan J,Cantón R,Calderón EJ,Del Campo R

doi

10.1016/j.mimet.2010.03.026

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

98-101

issue

1

eissn

0167-7012

issn

1872-8359

pii

S0167-7012(10)00113-2

journal_volume

82

pub_type

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