Comparison of RF body coils for MRI at 3  T: a simulation study using parallel transmission on various anatomical targets.


:The performance of multichannel transmit coil layouts and parallel transmission (pTx) RF pulse design was evaluated with respect to transmit B1 (B1 (+)) homogeneity and specific absorption rate (SAR) at 3 T for a whole body coil. Five specific coils were modeled and compared: a 32-rung birdcage body coil (driven either in a fixed quadrature mode or a two-channel transmit mode), two single-ring stripline arrays (with either 8 or 16 elements), and two multi-ring stripline arrays (with two or three identical rings, stacked in the z axis and each comprising eight azimuthally distributed elements). Three anatomical targets were considered, each defined by a 3D volume representative of a meaningful region of interest (ROI) in routine clinical applications. For a given anatomical target, global or local SAR controlled pTx pulses were designed to homogenize RF excitation within the ROI. At the B1 (+) homogeneity achieved by the quadrature driven birdcage design, pTx pulses with multichannel transmit coils achieved up to about eightfold reduction in local and global SAR. When used for imaging head and cervical spine or imaging thoracic spine, the double-ring array outperformed all coils, including the single-ring arrays. While the advantage of the double-ring array became much less pronounced for pelvic imaging, with a substantially larger ROI, the pTx approach still provided significant gains over the quadrature birdcage coil. For all design scenarios, using the three-ring array did not necessarily improve the RF performance. Our results suggest that pTx pulses with multichannel transmit coils can reduce local and global SAR substantially for body coils while attaining improved B1 (+) homogeneity, particularly for a "z-stacked" double-ring design with coil elements arranged on two transaxial rings.


NMR Biomed


NMR in biomedicine


Wu X,Zhang X,Tian J,Schmitter S,Hanna B,Strupp J,Pfeuffer J,Hamm M,Wang D,Nistler J,He B,Vaughan TJ,Ugurbil K,Van de Moortele PF




Has Abstract


2015-10-01 00:00:00












  • Phase imaging with multiple phase-cycled balanced steady-state free precession at 9.4 T.

    abstract::While phase imaging with a gradient echo (GRE) sequence is popular, phase imaging with balanced steady-state free precession (bSSFP) has been underexplored. The purpose of this study was to investigate anatomical and functional phase imaging with multiple phase-cycled bSSFP, in expectation of increasing spatial covera...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Kim JW,Kim SG,Park SH

    更新日期:2017-06-01 00:00:00

  • Proton change of parotid glands after gustatory stimulation examined by magnetic resonance imaging.

    abstract::The aim of this study was to investigate proton changes of the parotid gland after gustatory stimulation by semi-quantitative parameters and an empirical mathematical model (EMM) using high-temporal-resolution, double-echo, echo-planar imaging (EPI). Approved by a local institutional review board, this study examined ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Liu YJ,Lee YH,Chang HC,Chiu HC,Chiu TW,Hsu K,Pen CM,Hsu HH,Juan CJ

    更新日期:2018-03-01 00:00:00

  • The influence of obesity on cerebral blood flow in young adults using arterial spin labeling MRI.

    abstract::Obesity causes damage to several organs, including the brain. Recent studies have been focusing on understanding the mechanisms through which obesity affects brain structure and function using neuroimaging techniques. A functional biomarker, such as cerebral blood flow (CBF), is a powerful tool that can be used to exp...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Peng SL,Chen CM

    更新日期:2020-10-01 00:00:00

  • Improvement of resolution for brain coupled metabolites by optimized (1)H MRS at 7T.

    abstract::Resolution enhancement for glutamate (Glu), glutamine (Gln) and glutathione (GSH) in the human brain by TE-optimized point-resolved spectroscopy (PRESS) at 7 T is reported. Sub-TE dependences of the multiplets of Glu, Gln, GSH, γ-aminobutyric acid (GABA) and N-acetylaspartate (NAA) at 2.2-2.6 ppm were investigated wit...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Choi C,Dimitrov IE,Douglas D,Patel A,Kaiser LG,Amezcua CA,Maher EA

    更新日期:2010-11-01 00:00:00

  • Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI.

    abstract::The main aim of this study was to employ high-resolution MRI to investigate the spatiotemporal development of pathological features associated with contusive spinal cord injury (SCI) in mice. Experimental mice were subjected to either sham surgery or moderate contusive SCI. A 16.4-T small-animal MR system was employed...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Blomster LV,Cowin GJ,Kurniawan ND,Ruitenberg MJ

    更新日期:2013-02-01 00:00:00

  • In-vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO.

    abstract::Cerebral ischemia provokes tissue damage by two major patho-physiological mechanisms. Direct cell necrosis is induced by diminished access of neurons and glia to essential nutrients such as glucose and oxygen leading to energy failure. A second factor of cellular loss is related to the activation of immune-competent c...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Rausch M,Baumann D,Neubacher U,Rudin M

    更新日期:2002-06-01 00:00:00

  • Metabolite-specific NMR spectroscopy in vivo.

    abstract::An outline is presented of metabolite-specific in vivo NMR spectroscopy (particularly in brain). It reviews from a physical spectroscopist's perspective, the need for and the methods of observation of, individual metabolite resonances. ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审


    authors: Allen PS,Thompson RB,Wilman AH

    更新日期:1997-12-01 00:00:00

  • Quantitation by (1)H-NMR of dolichol, cholesterol and choline-containing lipids in extracts of normal and phathological thyroid tissue.

    abstract::Proton magnetic resonance spectroscopy at 1.9 T was used to quantify dolichols, cholesterols, choline-containing phospholipids and double bonds in unsaturated acyl chains in lipid extracts of four types of thyroid tissue [normal (n = 27), papillary cancer (n = 15), adenoma (n = 13) and Basedow disease (n = 6)]. In nor...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Yoshioka Y,Sasaki J,Yamamoto M,Saitoh K,Nakaya S,Kubokawa M

    更新日期:2000-11-01 00:00:00

  • Evaluating the feasibility of creatine-weighted CEST MRI in human brain at 7 T using a Z-spectral fitting approach.

    abstract::The current study aims to evaluate the feasibility of creatine (Cr) chemical exchange saturation transfer (CEST)-weighted MRI at 7 T in the human brain by optimizing the saturation pulse parameters and computing contrast using a Z-spectral fitting approach. The Cr-weighted (Cr-w) CEST contrast was computed from phanto...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Singh A,Debnath A,Cai K,Bagga P,Haris M,Hariharan H,Reddy R

    更新日期:2019-12-01 00:00:00

  • MOLLI and AIR T1 mapping pulse sequences yield different myocardial T1 and ECV measurements.

    abstract::Both post-contrast myocardial T1 and extracellular volume (ECV) have been reported to be associated with diffuse interstitial fibrosis. Recently, the cardiovascular magnetic resonance (CMR) field is recognizing that post-contrast myocardial T1 is sensitive to several confounders and migrating towards ECV as a measure ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Hong K,Kim D

    更新日期:2014-11-01 00:00:00

  • Noninvasive evaluation of renal pH homeostasis after ischemia reperfusion injury by CEST-MRI.

    abstract::Acute kidney injury (AKI) in mice caused by sustained ischemia followed by reperfusion is associated with acute tubular necrosis and renal dysfunctional blood flow. Although the principal role of the kidney is the maintenance of acid-base balance, current imaging approaches are unable to assess this important paramete...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Longo DL,Cutrin JC,Michelotti F,Irrera P,Aime S

    更新日期:2017-07-01 00:00:00

  • Linear drive birdcage coil for 23Na human head studies at 1.5 T.

    abstract::Progress in the development of non-proton NMR applications in medical research has been hampered by the generally low sensitivity of these nuclides as well as the lack of instrumentation readily available for studying these spins. For example, custom head coils suitable for sodium imaging of the human head are either ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Lim KO,Wolff S,Balaban RS

    更新日期:1989-09-01 00:00:00

  • Analysis of parametric histogram from dynamic contrast-enhanced MRI: application in evaluating brain tumor response to radiotherapy.

    abstract::Dynamic contrast-enhanced MRI (DCE MRI) has been used to study tumor response to treatment for many years. In this study, the modified full width at half-maximum (mFWHM), calculated from the wash-in slope histogram, is proposed as a parameter for the evaluation of changes in tumor heterogeneity which respond to radiot...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Peng SL,Chen CF,Liu HL,Lui CC,Huang YJ,Lee TH,Chang CC,Wang FN

    更新日期:2013-04-01 00:00:00

  • Orotracheal manganese-enhanced MRI (MEMRI): An effective approach for lung tumor detection.

    abstract::Lung cancer is a primary cause of cancer deaths worldwide. Timely detection of this pathology is necessary to delay or interrupt lung cancer progression, ultimately resulting in a possible better prognosis for the patient. In this context, magnetic resonance imaging (MRI) is especially promising. Ultra-short echo time...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Bianchi A,Gobbo OL,Dufort S,Sancey L,Lux F,Tillement O,Coll JL,Crémillieux Y

    更新日期:2017-11-01 00:00:00

  • Cluster analysis of DCE-MRI data identifies regional tracer-kinetic changes after tumor treatment with high intensity focused ultrasound.

    abstract::Evaluation of high intensity focused ultrasound (HIFU) treatment with MRI is generally based on assessment of the non-perfused volume from contrast-enhanced T1-weighted images. However, the vascular status of tissue surrounding the non-perfused volume has not been extensively investigated with MRI. In this study, clus...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Jacobs I,Hectors SJ,Schabel MC,Grüll H,Strijkers GJ,Nicolay K

    更新日期:2015-11-01 00:00:00

  • Rapid MR relaxometry using deep learning: An overview of current techniques and emerging trends.

    abstract::Quantitative mapping of MR tissue parameters such as the spin-lattice relaxation time (T1 ), the spin-spin relaxation time (T2 ), and the spin-lattice relaxation in the rotating frame (T1ρ ), referred to as MR relaxometry in general, has demonstrated improved assessment in a wide range of clinical applications. Compar...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Feng L,Ma D,Liu F

    更新日期:2020-10-15 00:00:00

  • Frontal lobe in vivo (31)P-MRS reveals gender differences in healthy controls, not in schizophrenics.

    abstract::Phosphorus-31 magnetic resonance spectroscopy ((31)P-MRS) has gained much interest in schizophrenia research in recent years since it allows the non-invasive measurement of high-energy phosphates and phospholipids in vivo. However, until now only differences in metabolite concentrations between certain brain areas of ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Riehemann S,Volz HP,Wenda B,Hübner G,Rössger G,Rzanny R,Sauer H

    更新日期:1999-12-01 00:00:00

  • Proton T2 relaxation of cerebral metabolites of normal human brain over large TE range.

    abstract::T2 of NAA, creatine and choline-containing compounds were measured in posterior frontal white matter and occipital grey matter in 10 healthy human volunteers. Decay curves comprised signals from eight TE times ranging from 30 to 800 ms with TR 2000 ms acquired with a PRESS sequence on a 1.5 T clinical scanner. Simulat...

    journal_title:NMR in biomedicine

    pub_type: 临床试验,杂志文章


    authors: Brief EE,Whittall KP,Li DK,MacKay AL

    更新日期:2005-02-01 00:00:00

  • Brain metabolism and blood flow in acute cerebral hypoxia studied by NMR spectroscopy and hydrogen clearance.

    abstract::We have developed a reliable, reproducible model of hypoxia in the gerbil. 1H and 31P NMR spectroscopy demonstrates that cerebral energy metabolism is very resistant to hypoxia. Cerebral blood flow (measured by hydrogen clearance) began to increase when the arterial oxygen tension (paO2) was reduced to 40-50 mm Hg, an...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Allen K,Busza AL,Crockard HA,Gadian DG

    更新日期:1992-01-01 00:00:00

  • Spin-echo and gradient-echo EPI of human brain activation using BOLD contrast: a comparative study at 1.5 T.

    abstract::In this study, Blood Oxygenation Level Dependent (BOLD) contrast in the detection of human brain activation was compared between spin-echo and gradient-echo echo-planar sequences at 1.5 T. Time course series of spin-echo and gradient-echo images containing the primary motor cortex were collected during rest (no finger...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Bandettini PA,Wong EC,Jesmanowicz A,Hinks RS,Hyde JS

    更新日期:1994-03-01 00:00:00

  • Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd-DTPA and USPIO-enhanced imaging.

    abstract::High grade and metastatic brain tumours exhibit considerable spatial variations in proliferation, angiogenesis, invasion, necrosis and oedema. Vascular heterogeneity arising from vascular co-option in regions of invasive growth (in which the blood-brain barrier remains intact) and neoangiogenesis is a major challenge ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Boult JK,Borri M,Jury A,Popov S,Box G,Perryman L,Eccles SA,Jones C,Robinson SP

    更新日期:2016-11-01 00:00:00

  • MRI measurements of cerebral deoxyhaemoglobin concentration [dHb]--correlation with near infrared spectroscopy (NIRS).

    abstract::Changes in physiological parameters such as cerebral blood flow, cerebral blood volume, oxygen extraction, and the size and distribution of cerebral blood vessels, result in changes in the local concentration of deoxyhaemoglobin ([dHb]). The purpose of this study was to quantitatively investigate the dependence of the...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Punwani S,Ordidge RJ,Cooper CE,Amess P,Clemence M

    更新日期:1998-10-01 00:00:00

  • Metabolite quantification and high-field MRS in breast cancer.

    abstract::In vivo 1H MRS is rapidly developing as a clinical tool for diagnosing and characterizing breast cancers. Many in vivo and in vitro experiments have demonstrated that alterations in concentrations of choline-containing metabolites are associated with malignant transformation. In recent years, considerable efforts have...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审


    authors: Haddadin IS,McIntosh A,Meisamy S,Corum C,Styczynski Snyder AL,Powell NJ,Nelson MT,Yee D,Garwood M,Bolan PJ

    更新日期:2009-01-01 00:00:00

  • Radio frequency coil technology for small-animal MRI.

    abstract::A review of the theory, technology, and use of radio frequency (RF) coils for small-animal MRI is presented. It includes a brief overview of MR signal-to-noise (S/N) analysis and discussions of the various coils commonly used in small-animal MR: surface coils, linear volume coils, birdcages, and their derivatives. The...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Doty FD,Entzminger G,Kulkarni J,Pamarthy K,Staab JP

    更新日期:2007-05-01 00:00:00

  • Magnetic resonance image segmentation using pattern recognition, and applied to image registration and quantitation.

    abstract::This review highlights various magnetic resonance image (MRI) segmentation algorithms that employ pattern recognition. The procedures are grouped into two categories: low- to intermediate-level, and high-level image processing. The former consists of grey level histogram analysis, texture definition, edge identificati...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审


    authors: Saeed N

    更新日期:1998-06-01 00:00:00

  • Detection of myocardial medium-chain fatty acid oxidation and tricarboxylic acid cycle activity with hyperpolarized [1-13 C]octanoate.

    abstract::Under normal conditions, the heart mainly relies on fatty acid oxidation to meet its energy needs. Changes in myocardial fuel preference are noted in the diseased and failing heart. The magnetic resonance signal enhancement provided by spin hyperpolarization allows the metabolism of substrates labeled with carbon-13 t...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Yoshihara HAI,Bastiaansen JAM,Karlsson M,Lerche MH,Comment A,Schwitter J

    更新日期:2020-03-01 00:00:00

  • Multi-center reproducibility of neurochemical profiles in the human brain at 7 T.

    abstract::The purpose of this work was to harmonize data acquisition and post-processing of single voxel proton MRS ((1) H-MRS) at 7 T, and to determine metabolite concentrations and the accuracy and reproducibility of metabolite levels in the adult human brain. This study was performed in compliance with local institutional hu...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,多中心研究


    authors: van de Bank BL,Emir UE,Boer VO,van Asten JJ,Maas MC,Wijnen JP,Kan HE,Oz G,Klomp DW,Scheenen TW

    更新日期:2015-03-01 00:00:00

  • Magnetic resonance elastography of skeletal muscle deep tissue injury.

    abstract::The current state-of-the-art diagnosis method for deep tissue injury in muscle, a subcategory of pressure ulcers, is palpation. It is recognized that deep tissue injury is frequently preceded by altered biomechanical properties. A quantitative understanding of the changes in biomechanical properties preceding and duri...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Nelissen JL,Sinkus R,Nicolay K,Nederveen AJ,Oomens CWJ,Strijkers GJ

    更新日期:2019-06-01 00:00:00

  • Amplification or obfuscation: is localization improving our clinical understanding of phosphorus metabolism?

    abstract::Localization techniques are considered an indispensable part of the clinical spectroscopy examination. The results are often a marked improvement in diagnostic information (amplification), but because of the introduction of new artifacts and the more prolonged examination time, some of the undoubted advantage is lost ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审


    authors: Ross B,Narasimhan PT,Tropp J,Derby KS

    更新日期:1989-12-01 00:00:00

  • Image-based tissue engineering of a total intervertebral disc implant for restoration of function to the rat lumbar spine.

    abstract::Nonbiological total disc replacement is currently being used for the treatment of intervertebral disc (IVD) disease and injury, but these implants are prone to mechanical wear, tear and possible dislodgement. Recently, tissue-engineered total disc replacement (TE-TDR) has been investigated as a possible alternative to...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章


    authors: Bowles RD,Gebhard HH,Dyke JP,Ballon DJ,Tomasino A,Cunningham ME,Härtl R,Bonassar LJ

    更新日期:2012-03-01 00:00:00