Abstract:
INTRODUCTION:high density lipoproteins (HDL) have important cardiovascular protective effects mediated by their role in reverse cholesterol transport as well as other functional activities, including significant anti-inflammatory and antioxidant properties. It has been shown that HDL anti-inflammatory and antioxidant functions are defective in metabolically stable diabetic patients; however they have not been evaluated during a hyperglycemic crisis. AIM:to determine the antioxidant activity of HDL during a severe diabetic decompensation and to analyze whether this function is restored after resolution of the acute event. METHODS:the antioxidant activity of HDL was measured in vitro by a fluorescent assay in plasma samples obtained from diabetic patients with acute metabolic decompensation at admission, recovery within the hospital and follow-up in ambulatory care. As a comparison, HDL particles from some healthy subjects were used as controls. RESULTS:the HDL antioxidant function was significantly reduced in patients during an acute diabetic decompensation compared with the control group, and was gradually restored reaching normal values during the ambulatory follow-up. Hyperglycemic crisis also showed low plasma paraoxonase-1 activity, which increased significantly during at follow-up. CONCLUSION:HDL particles isolated from acute diabetic descompensated patients exhibit a significantly and reversibly low antioxidant capacity, which is probably due to a reduced paraoxonase-1 activity. :Introducción: las lipoproteínas de alta densidad (HDL) tienen un importante efecto protector cardiovascular mediado por su función durante el transporte reverso del colesterol, así como por otras actividades, incluyendo una significativa acción antiinflamatoria y antioxidante. La funcionalidad antiinflamatoria y antioxidante de las HDL está alterada en los pacientes diabéticos crónicos estables, aunque no existe mayor información en caso de una crisis hiperglicémica. Objetivo: determinar si durante un estado de descompensación diabética aguda las partículas de HDL exhiben un deterioro de su función antioxidante y si esta logra recuperarse una vez resuelto el cuadro agudo. Métodos: la actividad antioxidante de las HDL se midió mediante un ensayo de fluorescencia in vitro en muestras plasmáticas de pacientes diabéticos con descompensación aguda obtenidas tanto al ingreso, alcanzada la resolución intrahospitalaria del evento agudo, así como en un control ambulatorio post-hospitalización. Como comparación, se analizaron partículas de HDL de algunos sujetos sanos como condición control. Resultados: la actividad antioxidante de las HDL en pacientes con descompensación diabética aguda fue significativamente menor a la observada en el grupo control sano, y esta se fue recuperando progresivamente hasta normalizarse en el momento del control ambulatorio. La crisis hiperglicémica también demostró una baja actividad plasmática de la enzima antioxidante paraoxonasa- 1, la cual aumentó significativamente en el control ambulatorio. Conclusión: las partículas de HDL presentes en pacientes con una descompensación diabética aguda presentan una reducción significativa y reversible de su capacidad antioxidante, probablemente como consecuencia de una alteración en la actividad de la paraoxonasa-1.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
Awad F,Contreras-Duarte S,Molina P,Quiñones V,Serrano V,Abbott E,Maiz A,Busso D,Rigotti Adoi
10.3305/nh.2015.32.3.9340subject
Has Abstractpub_date
2015-09-01 00:00:00pages
1131-8issue
3eissn
0212-1611issn
1699-5198journal_volume
32pub_type
杂志文章abstract:INTRODUCTION:Health education is one of the primary tools for health promotion, especially for those that will be responsible for educating on healthy habits in the future. OBJECTIVE:To improve healthy lifestyle habits in university students through an educational intervention based on gamification. METHOD:A cuasiexp...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.669
更新日期:2017-07-28 00:00:00
abstract:OBJECTIVE:To update the system for nutritional screening. The high prevalence of nutritional unstability that causes the Clinical Undernutrition (CU), especially within the hospitals and assisted residencies, makes it necessary to use screening tools for the constant control of undernutrition to combat it during its de...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2014.29.4.7275
更新日期:2014-01-13 00:00:00
abstract:OBJECTIVES/HYPOTHESIS:Presbycusis is the most prevalent cause of hearing-loss in the older, but pathogenesis is not well-know. The premise of this study is that hyperlipemia increase risk of age-related hearing-loss. PATIENTS AND METHODS:180 patient more than 65 years-old were studied. All patients had bilateral heari...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:obesity often leads to deregulation and disrupting of the function of adipokines, which leads to various altered conditions, including metabolic syndrome (MetS). Adiponectin is one of the main adipokines secreted by adipocytes. The ADIPQ gene polymorphism rs266729 (-11377 C>G) is significantly associated w...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03204
更新日期:2020-12-15 00:00:00
abstract:INTRODUCTION:The physical activity and adequate food plays a key role in improving health and the control of diseases. OBJECTIVE:This paper aims at determining the nutritional state through anthropometric measures, socioeconomic level, the most common illnesses and type of physical activity, beyond food consumption an...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2008-05-01 00:00:00
abstract:INTRODUCTION:Chile is a country that reaches the highest levels of overweight and obesity worldwide (66.7% of the Chilean population), with a group of college students tending to swell these numbers considered nutritionally vulnerable group. OBJECTIVE:To associate the consumption of fruits with nutritional status of C...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.31.5.8617
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:There is scarce and inconsistent information about gender-related differences in the hydration of sports persons, as well as about the effects of hydration on performance, especially during indoor sports. OBJECTIVE:To determine the physiological differences between genders during in indoor physical exerci...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,随机对照试验
doi:10.3305/nh.2014.29.3.7017
更新日期:2014-03-01 00:00:00
abstract:Introducción:la betatrofina es una novedosa adipoquina que provoca la proliferación de células β pancreáticas e interviene en el metabolismo de los lípidos. Objetivos: el propósito de este estudio es evaluar el papel de la betatrofina en el síndrome metabólico. Método:se llevó a cabo un estudio hospitalario de casos y...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.108
更新日期:2016-03-25 00:00:00
abstract::Los datos del estudio PREDYCES® nos revelaron que en España la desnutrición relacionada con la enfermedad (DRE) afecta a uno de cada cuatro pacientes hospitalizados. Esta cifra aumenta hasta el 36,8% en los pacientes hematológicos. Se calcula que un 20% de los pacientes oncológicos muere por complicaciones relacionada...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.180
更新日期:2016-06-03 00:00:00
abstract:BACKGROUND:Oncohematological diseases such as lymphoma or leukaemia affect an increasing number of newly diagnosed patients in Spain and other countries. Both disease and treatment may have a negatively impact in the nutritional status of the patient. Malnutrition is not uncommon among oncohematological patients. This ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2012.27.3.5863
更新日期:2012-05-01 00:00:00
abstract:INTRODUCTION:in relation to the student population, their class schedules, hours of study, budget shortages, among others, do not allow them to have good eating habits and sedentary ago. Within this context are the sports teams, which must deal with the above. OBJECTIVE:knowing the nutritional status of a group of col...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.6.9877
更新日期:2015-12-01 00:00:00
abstract::Dual-energy X ray absorptiometry (DEXA) is primarily used in the assessment of bone mineral. However, the transmissions of the two different energy beams in nonbone areas can be processed to calculate the amount of fat and free-fat mass of the soft tissues. We have compared the estimation of body fat mass (FM) by DEXA...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:The intragastric balloon is widely used for weight reduction in obese patients, but results are variable. We describe our results enhancing the importance of a Multidisciplinary Team (MT) taking part in the treatment. METHODS:A retrospective review was done concerning a total of 119 balloons , placed in 116...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract::The relationship between adequate folate intake, adequate serum levels, and lowering the risk of suffering from cardiovascular diseases, neural tube defects, neural illness and some kind of cancers have been widely studied. Because of the expected health benefits, the consumption of foods with high folate content or e...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:The pathophysiologic mechanisms that account for the development and persistence of anorexia nervosa (AN) remain unclear. With respect to the neuropsychological functioning, the executive functions have been reported to be altered, especially cognitive flexibility and decision-making processes. OBJECTIVES...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,meta分析,评审
doi:10.3305/nh.2014.29.3.7149
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Adolescence is an important period of nutritional vulnerability due to the increased dietary requirements. OBJECTIVE:To describe the nutritional status of adolescent cyclist and a group of normoactive controls. METHODS:The HELENA Dietary Assessment Tool was used to evaluate the nutritional intake of 20 a...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2013.28.4.6513
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:Dietary protein amount and source, hypertrophy resistance training (RT) and anabolicandrogenic steroids (AAS) may affect body weight and plasma and hepatic lipid profile. MATERIAL AND METHODS:157 adult male Wistar rats were randomly distributed in 16 experimental groups resulting in: normal-protein (NP) o...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2013.28.1.6055
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:the use of lipid emulsions together with glucose as a calorie source in parenteral nutrition has undisputed advantages. Their isotony and high calorie content mean they are essential for peripheric parenteral nutrition and in parenteral nutrition of long duration they are important in providing essential f...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:Currently there is a growing trend in the prevalence of overweight and obesity. This increased prevalence trend leads to an increase in the costs of health care. OBJECTIVE:The aim of the present study was to analyze the effects on physical fitness and bone mineral density through an intervention program o...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2014.30.3.7365
更新日期:2014-09-01 00:00:00
abstract::The refeeding syndrome can be defined as the metabolic alterations developed by the rapid nutrition repletion (oral, enteral as well as parenteral feeding) of severaly malnourished patients. Refeeding syndrome is a potentially fatal clinical condition and it is often underdiagnosed on non-specialized nutrition units. ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract:Introduction:Introduction: promoting healthy lifestyles already from the pediatric age for prevention of diseases at a short, mid and long-term is compulsory worldwide. Objectives: to know eating patterns and dietary habits, physical activity and sedentary behaviours in urban Spanish children aged one to nine years old...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.03348
更新日期:2021-01-13 00:00:00
abstract:INTRODUCTION:the evaluation of the body fat distribution by anthropometry can serve to identify excess visceral fat. This diagnosis will enable implementation of specific measures to both prevent and treat excess visceral fat in postmenopausal women. OBJECTIVE:the aim of this study was to analyze different anthropomet...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2015.32.6.9813
更新日期:2015-12-01 00:00:00
abstract::Tube feeding is a widely used medical treatment for providing nutrition to terminally ill patients. Long term nutritional support in these patients or patients with irreversible neurological deterioration create a host of ethical and legal conflicts with difficult solutions. This work looks at the cultural and ethical...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract::We examined the possible changes undergone in the form of feeding post liver-transplant patients admitted to our Intensive Care Unit (ICU), comparing 1989 and 1992. As biological nutritional parameters, we reviewed blood lymphocyte values and albumin prior to the transplant, immediately after, seven days following and...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract:Introduction:Objective: to evaluate a healthy food program for teachers and their educational transfer through an action plan for 3rd to 5th primary students, to improve their food habits and culinary skills. Methodology: a four months quasi-experimental prospective study was carried out, with qualitative measurements ...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.20960/nh.2190
更新日期:2019-04-10 00:00:00
abstract:INTRODUCTION:Food-Based Dietary Guidelines (FBDGs) are an initiative by the United Nations Food and Agriculture Organization (FAO) and the World Health Organization (WHO) designed to help countries establish their own nutrition education principles. Such principles should be expressed through clear and specific message...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.32.3.9362
更新日期:2015-09-01 00:00:00
abstract:Introduction:A large evidence-based reports a J-shaped association among moderate alcohol consumption and cardiovascular health. Low-moderate alcohol intake has been related to lower all-cause mortality (20%) and ischemic heart events (40%) compared to abstainers. The dose that is allegedly beneficial varies between 10...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.20960/nh.02811
更新日期:2019-08-27 00:00:00
abstract::Patient diagnosed with Crohn's Disease with inflammatory pattern that evolves stenosing-piercing, causing abdominal perforation and fecal peritonitis. She was underwent to three surgeries, leading to numerous complications and a torpid clinical course. Given the state of malnutrition on admission it was prescribed Tot...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章
doi:10.3305/nh.2012.27.5.5884
更新日期:2012-09-01 00:00:00
abstract::The authors present a prospective double blind test aimed at objectively determining the acceptance of flavoured orally administered enteric diets specific to patients with glucose metabolism alterations (Glucerna and Precitene Diabet), in the light of the taste disorders described in such patients. Sixty-two patients...
journal_title:Nutricion hospitalaria
pub_type: 临床试验,杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::Irritable bowel syndrome (IBS) is characterized by symptoms of abdominal pain and altered bowel habits. This common disorder is managed by varying clinical styles as no dominant therapeutic strategy has emerged. The pathophysiology of IBS remains unknown, but several lines of evidence link this disorder with the gut m...
journal_title:Nutricion hospitalaria
pub_type: 杂志文章,评审
doi:10.3305/nh.2015.31.sup1.8713
更新日期:2015-02-07 00:00:00