Feasibility study of patient-specific energy verification using a multilayer acrylic-disk radiation sensor.

Abstract:

PURPOSE:Obtaining an integral depth-dose (IDD) curve using a recently developed acrylic-disk radiation sensor (ADRS) is time-consuming because its single structure requires point-by-point measurements in a water phantom. The goal of this study was to verify the ability of a newly designed multilayer ADRS, composed of 20 layers, to measure the energy of proton pencil beam scanning (PBS) in patient-specific quality assurance (QA). MATERIALS AND METHODS:The multilayer ADRS consisted of a disk-type transmitter, with a diameter of 15 cm and with a thickness of 1 mm, surrounded by a thin optical fiber; this ADRS provided a higher spatial resolution than the single ADRS, which was 2 mm. The dosimetric characteristics of the multilayer ADRS were determined to accurately measure the energy delivered layer-by-layer. We selected five patients to verify the energy measured using the multilayer ADRS from the actual clinical proton therapy plans. The accuracy of the results measured using the multilayer ADRS was compared with that of measurements by a Bragg peak ionization chamber (IC) and that calculated by a Monte Carlo TOPAS simulation. RESULTS:The difference between the multilayer ADRS measurements and those of the TOPAS simulation was within 1% for all patients. The ranges, corresponding to the beam energies for each patient, measured using the multilayer ADRS were closer to those calculated using the TOPAS simulation than those measured using the Bragg peak IC. CONCLUSIONS:The multilayer ADRS is well suited to verifying the energy of a pencil beam. The acrylic materials used in its configuration make this device easier to use and more cost-effective than conventional detectors. This device, with its high extensibility and stability, may be applicable as a new dosimetry tool for PBS.

journal_name

Med Phys

journal_title

Medical physics

authors

Son J,Shin D,Kim T,Park S,Rah JE

doi

10.1002/mp.14326

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

3789-3796

issue

9

eissn

0094-2405

issn

2473-4209

journal_volume

47

pub_type

杂志文章
  • Evaluation of two methods of predicting MLC leaf positions using EPID measurements.

    abstract::In intensity modulated radiation treatments (IMRT), the position of the field edges and the modulation within the beam are often achieved with a multileaf collimator (MLC). During the MLC calibration process, due to the finite accuracy of leaf position measurements, a systematic error may be introduced to leaf positio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2335490

    authors: Parent L,Seco J,Evans PM,Dance DR,Fielding A

    更新日期:2006-09-01 00:00:00

  • Photon-beam subsource sensitivity to the initial electron-beam parameters.

    abstract::One limitation to the widespread implementation of Monte Carlo (MC) patient dose-calculation algorithms for radiotherapy is the lack of a general and accurate source model of the accelerator radiation source. Our aim in this work is to investigate the sensitivity of the photon-beam subsource distributions in a MC sour...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1884385

    authors: Fix MK,Keall PJ,Siebers JV

    更新日期:2005-04-01 00:00:00

  • Automatic detection of simulated motion blur in mammograms.

    abstract:PURPOSE:To use machine-learning algorithms and blur measure (BM) operators to automatically detect motion blur in mammograms. Motion blur has been reported to reduce lesion detection performance and mask small abnormalities, resulting in failure to detect them until they reach more advanced stages. Automatic detection ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14069

    authors: Kamona N,Loew M

    更新日期:2020-04-01 00:00:00

  • Effects of tumor motion in GRID therapy.

    abstract::Clinical and biological evidence suggest that the success of GRID therapy in debulking large tumors depends on the high peak-to-valley contrast in the dose distribution. In this study, we show that the peaks and valleys can be significantly blurred out by respiration-induced tumor motion, possibly affecting the clinic...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2977538

    authors: Naqvi SA,Mohiuddin MM,Ha JK,Regine WF

    更新日期:2008-10-01 00:00:00

  • Robust initialization of 2D-3D image registration using the projection-slice theorem and phase correlation.

    abstract:PURPOSE:The image registration literature comprises many methods for 2D-3D registration for which accuracy has been established in a variety of applications. However, clinical application is limited by a small capture range. Initial offsets outside the capture range of a registration method will not converge to a succe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3366252

    authors: van der Bom MJ,Bartels LW,Gounis MJ,Homan R,Timmer J,Viergever MA,Pluim JP

    更新日期:2010-04-01 00:00:00

  • An accurate method for direct dual-energy calibration and decomposition.

    abstract::We propose the use of conic and cubic surface equations (surfaces of second and third order) to directly approximate the dual-energy equations (the integral equations for the dual-energy log-signal functions, i.e., the negative logarithms of the relative detector signals, considered as functions of the basis-material ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596512

    authors: Cardinal HN,Fenster A

    更新日期:1990-05-01 00:00:00

  • Continuous time-dependence in computed tomography.

    abstract::Computed tomography is sensitive to changes in the imaged distribution during acquisition of the projection data. Previous investigations have emphasized discrete or discontinuous changes in the imaged object. Recent advances have motivated our investigation of object time-dependence characterized by a continuous func...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594458

    authors: Holden JE,Ip WR

    更新日期:1978-11-01 00:00:00

  • An experimentally validated couch and MLC tracking simulator used to investigate hybrid couch-MLC tracking.

    abstract:PURPOSE/OBJECTIVE:Couch and MLC tracking are two novel techniques to mitigate intrafractional tumor motion on a conventional linear accelerator, but both techniques still have residual dosimetric errors. Here, we first propose and experimentally validate a software tool to simulate couch and MLC tracking, and then use ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12104

    authors: Toftegaard J,Hansen R,Ravkilde T,Macek K,Poulsen PR

    更新日期:2017-03-01 00:00:00

  • Position detection accuracy of a novel linac-mounted intrafractional x-ray imaging system.

    abstract:PURPOSE:The authors have developed a system that monitors intrafractional target motion perpendicular to the treatment beam with the aid of radioopaque markers by means of separating kV image and megavoltage (MV) treatment field on a single flat-panel detector. METHODS:They equipped a research Siemens Artiste linear a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3665712

    authors: Fast MF,Krauss A,Oelfke U,Nill S

    更新日期:2012-01-01 00:00:00

  • Reduction of motion blurring artifacts using respiratory gated CT in sinogram space: a quantitative evaluation.

    abstract::Techniques have been developed for reducing motion blurring artifacts by using respiratory gated computed tomography (CT) in sinogram space and quantitatively evaluating the artifact reduction. A synthetic sinogram was built from multiple scans intercepting a respiratory gating window. A gated CT image was then recons...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2074187

    authors: Lu W,Parikh PJ,Hubenschmidt JP,Politte DG,Whiting BR,Bradley JD,Mutic S,Low DA

    更新日期:2005-11-01 00:00:00

  • Automated matching and segmentation of lymphoma on serial CT examinations.

    abstract::In patients with lymphoma, identification and quantification of the tumor extent on serial CT examinations is critical for assessing tumor response to therapy. In this paper, we present a computer method to automatically match and segment lymphomas in follow-up CT images. The method requires that target lymph nodes in...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2404617

    authors: Yan J,Zhao B,Curran S,Zelenetz A,Schwartz LH

    更新日期:2007-01-01 00:00:00

  • Investigation of a breathing surrogate prediction algorithm for prospective pulmonary gating.

    abstract:PURPOSE:A major challenge of four dimensional computed tomography (4DCT) in treatment planning and delivery has been the lack of respiration amplitude and phase reproducibility during image acquisition. The implementation of a prospective gating algorithm would ensure that images would be acquired only during user-spec...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3556589

    authors: White BM,Low DA,Zhao T,Wuenschel S,Lu W,Lamb JM,Mutic S,Bradley JD,El Naqa I

    更新日期:2011-03-01 00:00:00

  • Low-dose CT reconstruction using spatially encoded nonlocal penalty.

    abstract:PURPOSE:Computed tomography (CT) is one of the most used imaging modalities for imaging both symptomatic and asymptomatic patients. However, because of the high demand for lower radiation dose during CT scans, the reconstructed image can suffer from noise and artifacts due to the trade-off between the image quality and...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12523

    authors: Kim K,El Fakhri G,Li Q

    更新日期:2017-10-01 00:00:00

  • A method to compare supra-pubic ultrasound and CT images of the prostate: technique and early clinical results.

    abstract::We describe a unique method that allows the comparison of spatially registered ultrasound (SRUS) images and computed tomography-derived contours (CTDCs) that were acquired with a minimal time lapse. As such, we have a tool that will provide validation of the spatial accuracy of the US system and that will allow compar...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1644515

    authors: Molloy JA,Srivastava S,Schneider BF

    更新日期:2004-03-01 00:00:00

  • Medical applications of shortwave FM radar: remote monitoring of cardiac and respiratory motion.

    abstract:PURPOSE:This article introduces the use of low power continuous wave frequency modulated radar for medical applications, specifically for remote monitoring of vital signs in patients. METHODS:Gigahertz frequency radar measures the electromagnetic wave signal reflected from the surface of a human body and from tissue b...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3267038

    authors: Mostov K,Liptsen E,Boutchko R

    更新日期:2010-03-01 00:00:00

  • Mitigating differential baseline shifts in locally advanced lung cancer patients using an average anatomy model.

    abstract:BACKGROUND AND PURPOSE:Differential baseline shifts between primary tumor and involved lymph nodes in locally advanced lung cancer patients compromise the accuracy of radiotherapy. The purpose of this study was to evaluate the performance of an average anatomy model (AAM) derived from repeat imaging and deformable regi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12271

    authors: Abdoli M,Van Kranen SR,Stankovic U,Rossi MMG,Belderbos JSA,Sonke JJ

    更新日期:2017-07-01 00:00:00

  • A beam intensity monitor for the Loma Linda cancer therapy proton accelerator.

    abstract::A beam intensity monitor was tested in a 230-MeV proton beam at the Loma Linda Proton Therapy Accelerator during its commissioning at Fermi National Accelerator Laboratory. The intensity monitor was designed to regulate the beam intensity extracted from the proton synchrotron. The proton beam is tunable between 70 and...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596636

    authors: Coutrakon G,Miller D,Kross BJ,Anderson DF,DeLuca P Jr,Siebers J

    更新日期:1991-07-01 00:00:00

  • A dosimetry study of the Oncoseed 6711 using glass rod dosimeters and EGS5 Monte Carlo code in a geometry lacking radiation equilibrium scatter conditions.

    abstract:PURPOSE:The aim of this study was to develop a dose calculation method which is applicable to the interseed attenuation and the geometry lacking the equilibrium radiation scatter conditions in brachytherapy. METHODS:The dose obtained from measurement with a radiophotoluminescent glass rod dosimeter (GRD) was compared ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3590370

    authors: Tanaka K,Tateoka K,Asanuma O,Kamo K,Bengua G,Sato K,Ueda T,Takeda H,Takagi M,Hareyama M,Takada J

    更新日期:2011-06-01 00:00:00

  • Approximate 3D iterative reconstruction for SPECT.

    abstract::Compared with slice-by-slice approaches for SPECT reconstruction, three-dimensional iterative methods provide a more accurate physical model and an improved SPECT image. Clinical application of these methods, however, is limited primarily to their computational demands. This paper investigates the methods for approxim...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598030

    authors: Gilland DR,Jaszczak RJ,Riauka TA,Coleman RE

    更新日期:1997-09-01 00:00:00

  • A compensative model for the angle-dependence of motion estimates in noninvasive vascular elastography.

    abstract:PURPOSE:Atherosclerosis of peripheral cerebral arteries can lead to stroke either by stenosis formation or plaque rupture. This pathology is initiated by the alteration of arterial wall mechanical properties shown to be assessable by ultrasound elastography. Recently, noninvasive vascular elastography (NIVE) was introd...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3539701

    authors: Mercure E,Deprez JF,Fromageau J,Basset O,Soulez G,Cloutier G,Maurice RL

    更新日期:2011-02-01 00:00:00

  • Objective performance characteristics of a new asymmetric screen-film system.

    abstract::A study of the objective imaging characteristics of a new asymmetric screen-film system is presented herein. The system is characterized by high x-ray absorption asymmetric screens, and a low-noise, high-contrast asymmetric film having near-zero crossover. Comparisons are made with the imaging characteristics of two w...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597407

    authors: Van Metter R,Dickerson R

    更新日期:1994-09-01 00:00:00

  • Comparison of CBCT-based dose calculation methods in head and neck cancer radiotherapy: from Hounsfield unit to density calibration curve to deep learning.

    abstract:PURPOSE:Anatomical variations occur during head and neck (H&N) radiotherapy treatment. kV cone-beam computed tomography (CBCT) images can be used for daily dose monitoring to assess dose variations owing to anatomic changes. Deep learning methods (DLMs) have recently been proposed to generate pseudo-CT (pCT) from CBCT ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14387

    authors: Barateau A,De Crevoisier R,Largent A,Mylona E,Perichon N,Castelli J,Chajon E,Acosta O,Simon A,Nunes JC,Lafond C

    更新日期:2020-10-01 00:00:00

  • On the efficiency of photon beam treatment head simulations.

    abstract::The paper presents a theoretical derivation of the photon fluence simulation efficiency in photon beam treatment head simulations without and with bremsstrahlung splitting. The expressions obtained provide a rigorous explanation of the efficiency dependence on scoring zone size and splitting number and explain the lar...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1943808

    authors: Kawrakow I

    更新日期:2005-07-01 00:00:00

  • Mammogram synthesis using a three-dimensional simulation. III. Modeling and evaluation of the breast ductal network.

    abstract::A method is proposed for realistic simulation of the breast ductal network as part of a computer three-dimensional (3-D) breast phantom. The ductal network is simulated using tree models. Synthetic trees are generated based upon a description of ductal branching by ramification matrices (R matrices), whose elements re...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1586453

    authors: Bakic PR,Albert M,Brzakovic D,Maidment AD

    更新日期:2003-07-01 00:00:00

  • Poster - Thur Eve - 23: Statistical analysis and verification of the percentage depth dose calculation based on the tissue maximum ratio in external beam radiotherapy.

    abstract::The aim of this study is to perform a statistical analysis to verify the calculated percentage depth dose (PDD) based on the tissue maximum ratio (TMR) with the PDD measurements taken in water. 6 and 15 MV photon beams produced by a Varian linear 2100 C/D accelerator were used. PDDs and TMRs were measured at various d...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4740131

    authors: Isa M,Iqbal K,Afzal M,Buzdar S,Chow J

    更新日期:2012-07-01 00:00:00

  • High resolution 2D dose measurement device based on a few long scintillating fibers and tomographic reconstruction.

    abstract:PURPOSE:Patient-specific QA of highly conformal radiotherapy treatments are usually conducted using 2D or 3D dosimetry of the incident dose distribution in a water-equivalent phantom. However, dosimeters typically used for this task usually lack in either spatial resolution or dose accuracy. The purpose of this work is...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4736526

    authors: Goulet M,Archambault L,Beaulieu L,Gingras L

    更新日期:2012-08-01 00:00:00

  • Technical Note: Robust individual thermoluminescence dosimeter tracking using optical fingerprinting.

    abstract:PURPOSE:The thermoluminescence dosimeter (TLD) has desirable features including low cost, reusability, small size, and relatively low energy dependence. However, the commonly available poly-crystal TLDs (e.g., TLD-100) exhibit high interdetector variability that requires individual calibration for high detection accura...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13895

    authors: Shang D,Gu W,Landers A,Woods K,Yu V,Neph R,Tenn S,Sheng K

    更新日期:2020-01-01 00:00:00

  • The x-ray light valve: a potentially low-cost, digital radiographic imaging system-concept and implementation considerations.

    abstract::New x-ray radiographic systems based on large-area flat-panel technology have revolutionized our capability to produce digital x-ray images. However, these imagers are extraordinarily expensive compared to the systems they are replacing. Hence, there is a need for a low-cost digital imaging system for general applicat...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2837288

    authors: Webster CA,Koprinarov I,Germann S,Rowlands JA

    更新日期:2008-03-01 00:00:00

  • Robotic intrafractional US guidance for liver SABR: System design, beam avoidance, and clinical imaging.

    abstract:PURPOSE:To present a system for robotic 4D ultrasound (US) imaging concurrent with radiotherapy beam delivery and estimate the proportion of liver stereotactic ablative body radiotherapy (SABR) cases in which robotic US image guidance can be deployed without interfering with clinically used VMAT beam configurations. M...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4964454

    authors: Schlosser J,Gong RH,Bruder R,Schweikard A,Jang S,Henrie J,Kamaya A,Koong A,Chang DT,Hristov D

    更新日期:2016-11-01 00:00:00

  • GLAaS: an absolute dose calibration algorithm for an amorphous silicon portal imager. Applications to IMRT verifications.

    abstract::A new calibration algorithm (GLAaS) to derive absolute dose maps from images acquired with the Varian PV-aS500 electronic portal imager (based on amorphous silicon detectors) has been developed incorporating the dependence of detector response on primary and transmitted radiation and on field size. Detector calibratio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2218314

    authors: Nicolini G,Fogliata A,Vanetti E,Clivio A,Cozzi L

    更新日期:2006-08-01 00:00:00