Abstract:
PURPOSE:Atherosclerosis of peripheral cerebral arteries can lead to stroke either by stenosis formation or plaque rupture. This pathology is initiated by the alteration of arterial wall mechanical properties shown to be assessable by ultrasound elastography. Recently, noninvasive vascular elastography (NIVE) was introduced for noninvasive imaging of the mechanical properties of superficial arteries as markers of vulnerable plaques. However, NIVE motion estimates are angle-dependent, with optimal scanning angle being represented by the alignment of tissue motion with ultrasound beam orientation. The objective of this study was to introduce a model that compensates for such angle-dependence in order to reduce the bias on strain estimates, namely, when investigating longitudinal vessel segments. METHODS:The model is based on the Lagrangian speckle model estimator (LSME) because the LSME assesses the 2D-deformation matrix required to compute the scanning angle. RESULTS:Experiments on vessel-mimicking phantoms indicated that such a model enables the estimation of scanning angle with less than 3-degrees error. The method was also validated in vivo in human carotid arteries where less than 4-degrees error was observed. In both cases, the compensative model estimated the inclination angles with low variability. CONCLUSION:Angle-dependence may be an important factor to consider in avoiding potentially distort clinical diagnoses. Results, reported in this article, suggest that the LSME-based compensative model might be considered as a very interesting and promising clinical tool for NIVE applications.
journal_name
Med Physjournal_title
Medical physicsauthors
Mercure E,Deprez JF,Fromageau J,Basset O,Soulez G,Cloutier G,Maurice RLdoi
10.1118/1.3539701subject
Has Abstractpub_date
2011-02-01 00:00:00pages
727-35issue
2eissn
0094-2405issn
2473-4209journal_volume
38pub_type
杂志文章相关文献
MEDICAL PHYSICS文献大全abstract:PURPOSE:Examine the use of TomoDose for Tomotherapy quality assurance. METHODS:Baseline TomoDose profiles are acquired annually in accordance with TG-148. During monthly quality assurance, TomoDose is irradiated with a static beam and referenced to baseline. Differences between superimposed profiles are evaluated mont...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4735202
更新日期:2012-06-01 00:00:00
abstract::Neutron cross sections for nonelastic and elastic reactions on a range of elements have been evaluated for incident energies up to 150 MeV. These cross sections agree well with experimental cross section data for charged-particle production as well as neutron and photon production. Therefore they can be used to determ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.598601
更新日期:1999-06-01 00:00:00
abstract::Modulation of the activity of the subthalamic nucleus (STN) using deep brain stimulation (DBS) in patients with advanced Parkinson's disease is the most common procedure performed today by functional neurosurgeons. The STN contours cannot be entirely identified on common 1.5 T images; in particular, the ventromedial b...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2936229
更新日期:2008-07-01 00:00:00
abstract::The feasibility of using film dosimetry data as the input data for patient treatment planning was evaluated. The central-axis depth dose and the off-axis ratios obtained from film measurements in a solid phantom were compared with those of ion-chamber measurements in water. Two techniques were used to generate isodose...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.596409
更新日期:1989-11-01 00:00:00
abstract:PURPOSE:The availability of accurate and simple models for the estimation of x-ray spectra is of great importance for system simulation, optimization, or inclusion of photon energy information into data processing. There is a variety of publicly available tools for estimation of x-ray spectra in radiology and mammograp...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4837220
更新日期:2014-01-01 00:00:00
abstract::A slat collimator in single photon emission computed tomography consists of a set of parallel slats. As the collimator spins, the detector measures a one-dimensional projection data set. A complete data set can be obtained by rotating the detector/collimator assembly around the object (patient) while the collimator sp...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1485057
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The purpose of this study is to develop a deep learning-based approach to simultaneously segment five pelvic organs including prostate, bladder, rectum, left and right femoral heads on cone-beam CT (CBCT), as required elements for prostate adaptive radiotherapy planning. MATERIALS AND METHODS:We...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14196
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To measure patient-specific maximum skin dose (MSD) associated with CT fluoroscopy (CTF) lung biopsies and to compare measured MSD with the MSD estimated from phantom measurements, as well as with the CTDIvol of patient examinations. METHODS:Data from 50 patients with lung lesions who underwent a CT fluoroscop...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4884231
更新日期:2014-07-01 00:00:00
abstract::Breast density is a strong predictor of the failure of mammography screening to detect breast cancer and is a strong predictor of the risk of developing breast cancer. The many imaging options that are now available for imaging dense breasts show great promise, but there is still the question of determining which wome...
journal_title:Medical physics
pub_type: 杂志文章,评审
doi:10.1118/1.4935141
更新日期:2015-12-01 00:00:00
abstract::A clamp-on current probe utilizing the Hall effect was used to determine x-ray tube current. This noninvasive technique was compared to two other methods of mA measurement: the Machlett Dynalyzer and the mR/mAs linearity method. Three diagnostic x-ray units were used in the comparison; two modern three-phase rooms and...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.596080
更新日期:1987-03-01 00:00:00
abstract::The 1983 AAPM protocol for the determination of absorbed dose from high-energy photon and electron beams recommends using Pion (the reciprocal of collection efficiency), as determined by the two-voltage technique, to correct for recombination losses in ionization chambers. Methods and data for the determination of ion...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.595574
更新日期:1984-11-01 00:00:00
abstract::The output factor for a therapy photon beam is defined as the dose per monitor unit relative to the dose per monitor unit in a reference field. Convolution models for photon dose calculations yield the dose in units normalized to the incident energy fluence with phantom scatter intrinsically modeled. Output factors ca...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.596859
更新日期:1992-03-01 00:00:00
abstract::The assessment of differential left and right lung function is important for patients under consideration for lung resection procedures such as single lung transplantation. We developed an automated, knowledge-based segmentation algorithm for purposes of deriving functional information from dynamic computed tomography...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.598898
更新日期:2000-03-01 00:00:00
abstract::The introduction of negative pions into cancer therapy has required the construction of large new proton accelerators together with special magnetic systems to form and direct the pion beam to a patient. A summary is presented of the fundamental properties of pions and of the methods used to study the therapeutic beam...
journal_title:Medical physics
pub_type: 杂志文章,评审
doi:10.1118/1.594868
更新日期:1981-05-01 00:00:00
abstract:PURPOSE:To evaluate the accuracy of skin dose determination for composite multibeam 3D conformal radiation therapy (3DCRT) and intensity modulated radiation therapy (IMRT) treatments using optically stimulated luminescent dosimeters (OSLDs) and Eclipse treatment planning system. METHODS:Surface doses measured by OSLDs...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4890795
更新日期:2014-08-01 00:00:00
abstract::Administration of x-ray contrast agents during heart catheterization examination increases the absorbed radiation dose in tissue. To estimate the dose absorbed by the blood of children undergoing diagnostic heart catheterization and angiocardiography, a number of measurements and calculations were conducted. First, en...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.594613
更新日期:1979-11-01 00:00:00
abstract:PURPOSE:To formulate convex planning objectives of treatment plan multicriteria optimization with explicit relationships to the dose-volume histogram (DVH) statistics used in plan quality evaluation. METHODS:Conventional planning objectives are designed to minimize the violation of DVH statistics thresholds using pena...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.12146
更新日期:2017-06-01 00:00:00
abstract::Highly focused dose distributions for radiosurgery applications are successfully achieved using either multiple static high-energy particle beams or multiple-arc circular x-ray beams from a linac. It has been suggested that conformal x-ray techniques using dynamically shaped beams with a moving radiation source would ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.597654
更新日期:1995-12-01 00:00:00
abstract::Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which ...
journal_title:Medical physics
pub_type: 杂志文章,评审
doi:10.1002/mp.12299
更新日期:2017-08-01 00:00:00
abstract::We adapted a small sodium iodide scintillation detector for rapid, in vivo localization of a lost brachytherapy seed. Using the detector, we were able to locate and remove an Ir-192 seed that was not visible to the unaided eye. ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.595528
更新日期:1984-07-01 00:00:00
abstract:PURPOSE:To develop a pharmacokinetic modelfree framework to analyze the dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) data for assessment of response of brain metastases to radiation therapy. METHODS:Twenty patients with 45 analyzable brain metastases had MRI scans prior to whole brain radiation thera...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4842556
更新日期:2014-01-01 00:00:00
abstract::A new high dose rate 20 mm 32P intravascular brachytherapy (IVB) beta source used with automated stepping has recently been introduced. The AAPM Task Group 60 recommends that beta IVB sources should have well characterized dosimetric parameters in water. In this study, Monte Carlo simulations (MCNPX v 2.4) were used t...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1646651
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:At our institution, all proton patient plans undergo patient-specific quality assurance (PSQA) prior to treatment delivery. For intensity-modulated proton beam therapy, quality assurance is complex and time consuming, and it may involve multiple measurements per field. We reviewed our PSQA workflow and identifi...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.13246
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:This work concerns computed tomography (CT)-based cardiac functional analysis (CFA) with a reduced radiation dose. As CT-CFA requires images over the entire heartbeat, the scans are often performed at 10-20% of the tube current settings that are typically used for coronary CT angiography. A large image noise th...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.12425
更新日期:2017-09-01 00:00:00
abstract::In the present investigation, the necessary tests for implementing a quality assurance program for a commercial treatment planning system (TPS), recently installed at Sao Paulo University School of Medicine Clinicas Hospital-Brazil, was established and performed in accordance with the new IAEA publication TRS 430, and...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2742779
更新日期:2007-07-01 00:00:00
abstract::New radiation therapy techniques such as IMRT present significant efficiency due to their highly conformal dose distributions. A consequence of the complexity of their dose distributions (high gradients, small irradiation fields, low dose distribution, ...) is the requirement for better precision quality assurance tha...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2897966
更新日期:2008-05-01 00:00:00
abstract::A system for measuring two-dimensional (2D) dose distributions in orthogonal anatomical planes in the cranium was developed and used to evaluate the accuracy of coplanar conformal therapy using ExacTrac image guidance. Dose distributions were measured in the axial, sagittal, and coronal planes using a CIRS (Computeriz...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2955751
更新日期:2008-08-01 00:00:00
abstract::In conventional dose optimization algorithms, in brachytherapy, multiple objectives are expressed in terms of an aggregating function which combines individual objective values into a single utility value, making the problem single objective, prior to optimization. A multiobjective genetic algorithm (MOGA) was develop...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.598697
更新日期:1999-09-01 00:00:00
abstract::Intrafraction organ motion can limit the advantage of highly conformal dose techniques such as intensity modulated radiation therapy (IMRT) due to target position uncertainty. To ensure high accuracy in beam targeting, real-time knowledge of the target location is highly desired throughout the beam delivery process. T...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2905225
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:Current on-board imaging systems commonly used by modern linear accelerators (LINACs) have a limited field of view (FOV) for a cone-beam CT (CBCT) scan, which is typically less than 50 cm. Consequently, truncation artifacts often occur for large patients. The goal of this work is to investigate a novel method t...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3514130
更新日期:2010-12-01 00:00:00