Abstract:
PURPOSE:At our institution, all proton patient plans undergo patient-specific quality assurance (PSQA) prior to treatment delivery. For intensity-modulated proton beam therapy, quality assurance is complex and time consuming, and it may involve multiple measurements per field. We reviewed our PSQA workflow and identified the steps that could be automated and developed solutions to improve efficiency. METHODS:We used the treatment planning system's (TPS) capability to support C# scripts to develop an Eclipse scripting application programming interface (ESAPI) script and automate the preparation of the verification phantom plan for measurements. A local area network (LAN) connection between our measurement equipment and shared database was established to facilitate equipment control, measurement data transfer, and storage. To improve the analysis of the measurement data, a Python script was developed to automatically perform a 2D-3D γ-index analysis comparing measurements in the plane of a two-dimensional detector array with TPS predictions in a water phantom for each acquired measurement. RESULTS:Device connection via LAN granted immediate access to the plan and measurement information for downstream analysis using an online software suite. Automated scripts applied to verification plans reduced time from preparation steps by at least 50%; time reduction from automating γ-index analysis was even more pronounced, dropping by a factor of 10. On average, we observed an overall time savings of 55% in completion of the PSQA per patient plan. CONCLUSIONS:The automation of the routine tasks in the PSQA workflow significantly reduced the time required per patient, reduced user fatigue, and frees up system users from routine and repetitive workflow steps allowing increased focus on evaluating key quality metrics.
journal_name
Med Physjournal_title
Medical physicsauthors
Hernandez Morales D,Shan J,Liu W,Augustine KE,Bues M,Davis MJ,Fatyga M,Johnson JE,Mundy DW,Shen J,Younkin JE,Stoker JBdoi
10.1002/mp.13246subject
Has Abstractpub_date
2019-01-01 00:00:00pages
5-14issue
1eissn
0094-2405issn
2473-4209journal_volume
46pub_type
杂志文章相关文献
MEDICAL PHYSICS文献大全abstract::In a recent paper of Miller et al. (Med. Phys. 43(5), 2141-2152 (2016), the voltage dependence polarity effect of microionization chambers was studied. It was identified that polarity effect arises from the difference in electric potential between the collecting electrode and the guard electrode, which in turn deforms...
journal_title:Medical physics
pub_type: 信件
doi:10.1002/mp.12019
更新日期:2017-03-01 00:00:00
abstract::Transthoracic electrical impedance Z consists of a constant baseline component Z0 and the time variable component delta Z such that Z = Z0 + delta Z. The first time derivative of Z has a negative peak, the magnitude of which is (dZ/dt)min. Measurements of 170 volunteers show that (dZ/dt)min is a function of the consta...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.594910
更新日期:1981-01-01 00:00:00
abstract:PURPOSE:IAEA TRS-398 notes that cylindrical ionization chambers are preferred for reference proton dosimetry. If a cylindrical ionization chamber is used in a phantom to measure the dose as a function of depth, the effective point of measurement (EPOM) must be taken into account. IAEA TRS-398 recommends a displacement ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4921617
更新日期:2015-07-01 00:00:00
abstract::The measurement of output factors for small fields is challenging and can lead to large dose errors in patient treatments if corrections for detector size and scatter from high-Z material are not applied. Due to its high spatial resolution and near tissue equivalence, GAFCHROMIC® film potentially provides a correction...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4740095
更新日期:2012-07-01 00:00:00
abstract:PURPOSE:Multiple commercial, open-source, and academic software tools exist for objective quantification of lung density in computed tomography (CT) images. The purpose of this study was to evaluate the intersoftware reproducibility of CT lung density measurements. METHODS:Computed tomography images from 50 participan...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.14130
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To investigate the optimal use of XR-RV3 GafChromic(®) films to assess patient skin dose in interventional radiology while addressing the means to reduce uncertainties in dose assessment. METHODS:XR-Type R GafChromic films have been shown to represent the most efficient and suitable solution to determine patie...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4922132
更新日期:2015-07-01 00:00:00
abstract::The validity of conclusions drawn from multi-institutional radiotherapy studies is dependent upon the degree to which participating hospitals adhere to study requirements. A major effort undertaken by the Quality Assurance Review Center (QARC) assesses whether or not patient data which are deemed evaluable actually co...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.595221
更新日期:1982-03-01 00:00:00
abstract:PURPOSE:The aim of this work is to investigate the predictive power of a common conventional intensity modulated radiation therapy (IMRT) quality assurance (QA) performance metric, the gamma passing rate (%GP), through the analysis of the sensitivity and of the correlation between %GP and different dose discrepancies b...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4767763
更新日期:2012-12-01 00:00:00
abstract::Functional single photon emission computed tomography (SPECT) images of brain activation are based on a comparison of base line and activation images. The correctness of the functional images depends, among other factors, on the accurate spatial registration (alignment) of the base line and activation image data. The ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.597228
更新日期:1994-12-01 00:00:00
abstract:PURPOSE:The depth dose of a monoenergetic broad parallel proton beam has been modeled in a number of ways, but evidently not yet for oblique incidence. The purpose of this investigation is to find an accurate analytic formula for this case, which can then be used to model the depth dose of a broad beam with an initial ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3495969
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:Determine the effective point of measurement (EPOM) of 12 thimble ion chambers, including miniature chambers and three models widely used for clinical reference dosimetry. The EPOM is the point at which the measured dose would arise in the measurement medium in the absence of the probe: For cylindrical chambers...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3266750
更新日期:2010-01-01 00:00:00
abstract::The purpose of this paper is to determine the correlation between dose-volume histogram (DVH) and dose wall-histogram (DWH) in the evaluation of rectal complications for prostate cancer patients treated with three-dimensional conformal radiotherapy (3D-CRT). A retrospective analysis of DVHs and DWHs of a subset of 25 ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1951427
更新日期:2005-08-01 00:00:00
abstract:PURPOSE:The authors describe a design for prepatient region of interest attenuators (ROIAs) to reduce dose area product (DAP) for clinical use. The authors describe a model to predict DAP values from x-ray technique parameters recorded during a clinical procedure for image sequences obtained in the presence or absence ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4903898
更新日期:2015-01-01 00:00:00
abstract::Manganese (Mn) is an essential nutrient for growth and development. Unfortunately, overexposure can lead to neurological damage, which is manifested as a movement disorder marked by tremors. Preclinical symptoms have been found in populations occupationally exposed to the element, and it is suggested that in late stag...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1517613
更新日期:2002-11-01 00:00:00
abstract::A combination of Monte Carlo, convolution, and experimental techniques have been used to investigate bremsstrahlung production at 50 MeV in full-range targets to produce narrow elementary photon beams for scanning. Calculations using the ITS 3.0 Monte Carlo system for various target designs, including particle transpo...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.597681
更新日期:1996-04-01 00:00:00
abstract::A four-parameter Laplace transform pair model, which accurately reconstructs an experimental bremsstrahlung spectrum from attenuation data, is presented. Computed spectral values with both aluminum and copper attenuators generally agree with experimental 70-kVp data to better than 2%. Reconstructed spectra at other kV...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.595193
更新日期:1982-11-01 00:00:00
abstract:PURPOSE:The first main aim of this study was to illustrate the absorbed dose rate distribution from 177Lu in sections of xenografted prostate cancer (PCa) tumors using high resolution digital autoradiography (DAR) and compare it with hypothetical identical radioactivity distributions of 90Y or 7 MeV alpha-particles. Th...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4967877
更新日期:2016-12-01 00:00:00
abstract::A new factor for shifting isodoes curves for oblique Co-60 photon beams has been deduced. Like the two other known factors, this shift factor depends on the source-to-surface distance (SSD), the depth dose (D) and the derivative of D with depth. A comparison of corrected dose distributions has been made by using the t...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.594688
更新日期:1980-05-01 00:00:00
abstract:PURPOSE:Current treatment planning for 90 Y radioembolization estimates lung mean dose (LMD) by measuring the lung shunt fraction (LSF) from 99m Tc-macroaggregated albumin (MAA) planar imaging and assuming a 1-kg lung mass. This methodology, however, overestimates LSF and LMD and could therefore unnecessarily limit the...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.13575
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:The paper presents a complete computer-aided detection (CAD) system for the detection of lung nodules in computed tomography images. A new mixed feature selection and classification methodology is applied for the first time on a difficult medical image analysis problem. METHODS:The CAD system was trained and t...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.3633941
更新日期:2011-10-01 00:00:00
abstract::Treatment of cervical cancer often involves intracavitary high dose rate (HDR) brachytherapy. Dose delivered to the bladder and rectum are typically estimated using the ICRU reference points. Dose to the sigmoid and small bowel are not estimated, yet these organs typically exhibit significant complication rates. The o...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.2965957
更新日期:2008-07-01 00:00:00
abstract::A method to determine the bone mineral density of the calcaneum has been reported earlier by our laboratory. In this method, the calcaneum is irradiated by a 60-keV photon beam from 241Am source and both the coherent and Compton scattered photons are detected by a high-purity Ge detector. The bone mineral density is d...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.595669
更新日期:1985-07-01 00:00:00
abstract:PURPOSE:The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. METHODS:Balanced data according to the one-factor random effect model were assumed. RESULTS:Analysis-of-variance (anova)-based computation was ap...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4961397
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To improve image quality and reduce imaging dose in CBCT for radiation therapy applications and to realize near real-time image reconstruction based on use of a fast convergence iterative algorithm and acceleration by multi-GPUs. METHODS:An iterative image reconstruction that sought to minimize a weighted leas...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4735747
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:MR-guided radiation therapy (RT) offers unparalleled soft tissue contrast for localization and target tracking. However, MRI distortions may be detrimental to high precision RT. This work characterizes the gradient nonlinearity (GNL) and total distortions over the first year of clinical operation of a 0.35T MR-...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1002/mp.13467
更新日期:2019-05-01 00:00:00
abstract::Positron emission mammography (PEM) is a new, specialized imaging modality utilizing PET radiopharmaceuticals to detect breast cancer. The capabilities and limitations of PEM in detecting breast tumors were investigated with a series of phantom experiments. The PEM imager was mounted on a standard Lorad biopsy table (...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.1287439
更新日期:2000-08-01 00:00:00
abstract::An analytic expression is derived for the transmission of isotropic scattered radiation incident upon an ideal parallel grid. It is found that the expression for the transmission usually found in the literature overestimates the transmission by approximately a factor of two. ...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.594877
更新日期:1981-11-01 00:00:00
abstract::A method is presented for calculation of transmission functions for high energy photon beams through patients. These functions are being used in our clinic for prediction of portal dose images (PDIs) which are compared with PDIs measured with an electronic portal imaging device (EPID). The calculations are based on th...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.598293
更新日期:1998-06-01 00:00:00
abstract:PURPOSE:Magnetic resonance imaging (MRI) is increasingly used for radiotherapy target delineation, image guidance, and treatment response monitoring. Recent studies have shown that an entire external x-ray radiotherapy treatment planning (RTP) workflow for brain tumor or prostate cancer patients based only on MRI refer...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4958677
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:When an intensity-modulated radiation beam is delivered to a moving target, the interplay effect between dynamic beam delivery and the target motion due to miss-synchronization can cause unpredictable dose delivery. The portal dose image in electronic portal imaging device (EPID) represents radiation attenuated...
journal_title:Medical physics
pub_type: 杂志文章
doi:10.1118/1.4799941
更新日期:2013-05-01 00:00:00