Bremsstrahlung production at 50 MeV in different target materials and configurations.

Abstract:

:A combination of Monte Carlo, convolution, and experimental techniques have been used to investigate bremsstrahlung production at 50 MeV in full-range targets to produce narrow elementary photon beams for scanning. Calculations using the ITS 3.0 Monte Carlo system for various target designs, including particle transport through the treatment head of an MM5O racetrack microtron and a water phantom, have been compared to experimental dose profiles from narrow photon beams at 10-cm depth in water. A reduction in the ITS 3.0 default substep size has been found necessary even for incomplete agreement, in consistency with the findings of Faddegon and Rogers [Nucl. Instrum. Meth. A 327, 556-565 (1993)] for a different experimental setup and energy using the previous version of ITS. Results show that the calculated shape of the tail of dose distributions from narrow photon beams agrees well with measurements, but CYLTRAN/ITS 3.0 fails to reproduce the central part of the distribution. The discrepancy at small angles, reported previously for EGS4 and ITS 2.1 simulations, possess a limitation to Monte Carlo simulations of narrow photon beams used in scanned systems of clinical accelerators. Radial dose profiles have been calculated by convolution of the energy fluence at the exit of the target with one polyenergetic Monte Carlo calculated dose kernel and also a database consisting of ten different dose kernels corresponding to different monoenergetic photon pencil beams for comparison. The agreement with the much slower fully detailed Monte Carlo calculations was better when using the database kernels than the polyenergetic kernel. Results for the mean energy, mean polar angle, and energy fluence at different depths within various targets have been obtained. These are discussed in the context of the design characteristics of bremsstrahlung targets with emphasis on their utilization for scanning photon beam techniques.

journal_name

Med Phys

journal_title

Medical physics

authors

Sätherberg A,Andreo P,Karlsson M

doi

10.1118/1.597681

subject

Has Abstract

pub_date

1996-04-01 00:00:00

pages

495-503

issue

4

eissn

0094-2405

issn

2473-4209

journal_volume

23

pub_type

杂志文章
  • Imaging of moving fiducial markers during radiotherapy using a fast, efficient active pixel sensor based EPID.

    abstract:PURPOSE:The purpose of this work was to investigate the use of an experimental complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) for tracking of moving fiducial markers during radiotherapy. METHODS:The APS has an active area of 5.4 × 5.4 cm and maximum full frame read-out rate of 20 frame s(-1),...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3651632

    authors: Osmond JP,Zin HM,Harris EJ,Lupica G,Allinson NM,Evans PM

    更新日期:2011-11-01 00:00:00

  • System considerations in CCD-based x-ray imaging for digital chest radiography and digital mammography.

    abstract::System modeling is used to investigate the effect of various system parameters on the image quality in CCD-based x-ray imaging systems. The systems considered consist of a typical phosphor-based scintillating screen coupled to a CCD through lens or fiberoptic taper. Two applications, chest radiography and mammography,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598072

    authors: Hejazi S,Trauernicht DP

    更新日期:1997-02-01 00:00:00

  • Small-field electron dosimetry for the Philips SL25 linear accelerator.

    abstract::Electron-beam characteristics of a Philips SL25 linear accelerator have been studied. Central-axis percentage depth doses, cross-beam profiles and beam output factors of 6-, 10-, and 20-MeV beams, selected from the available energy range of 4 to 22 MeV, are reported in this paper. The main thrust of this work is to de...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596471

    authors: Rashid H,Islam MK,Gaballa H,Rosenow UF,Ting JY

    更新日期:1990-07-01 00:00:00

  • Electron dose calculation using multiple-scattering theory. A. Gaussian multiple-scattering theory.

    abstract::This article is the first in a series on the calculation of electron dose using multiple-scattering theory. In it we develop a unified theory, which we term Gaussian multiple-scattering theory, starting from a number of contributions already in the literature: the Fermi-Eyges multiple-scattering theory, the Yang path ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596166

    authors: Jette D

    更新日期:1988-03-01 00:00:00

  • Differences in the lesion formation process between focused ultrasound and microwave ablations.

    abstract::The objective is to understand the differences in the lesion formation processes between microwave and high-intensity focused ultrasound (HIFU) ablation. The lesions formed by microwaves and HIFU were real-time monitored and compared using transparent tissue-mimicking phantoms at 60 and 70 W of driving electrical powe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2193689

    authors: Chen WS,Wu CC,Fang HY,Liu HL

    更新日期:2006-05-01 00:00:00

  • A novel computer-aided lung nodule detection system for CT images.

    abstract:PURPOSE:The paper presents a complete computer-aided detection (CAD) system for the detection of lung nodules in computed tomography images. A new mixed feature selection and classification methodology is applied for the first time on a difficult medical image analysis problem. METHODS:The CAD system was trained and t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3633941

    authors: Tan M,Deklerck R,Jansen B,Bister M,Cornelis J

    更新日期:2011-10-01 00:00:00

  • Fully automated segmentation of oncological PET volumes using a combined multiscale and statistical model.

    abstract::The widespread application of positron emission tomography (PET) in clinical oncology has driven this imaging technology into a number of new research and clinical arenas. Increasing numbers of patient scans have led to an urgent need for efficient data handling and the development of new image analysis techniques to ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2432404

    authors: Montgomery DW,Amira A,Zaidi H

    更新日期:2007-02-01 00:00:00

  • Patient doses and projection angle in cone beam CT.

    abstract:PURPOSE:To investigate how x-ray tube projection angle affects organ and effective doses to patients undergoing a CT examination on a cone beam scanner. METHODS:The authors investigated two cone beam CT systems that use a flat panel detector to capture the x-ray pattern transmitted through patients. One system had the...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3397458

    authors: He W,Huda W,Magill D,Tavrides E,Yao H

    更新日期:2010-05-01 00:00:00

  • Clinical evaluation of a commercial orthopedic metal artifact reduction tool for CT simulations in radiation therapy.

    abstract:PURPOSE:Severe artifacts in kilovoltage-CT simulation images caused by large metallic implants can significantly degrade the conspicuity and apparent CT Hounsfield number of targets and anatomic structures, jeopardize the confidence of anatomical segmentation, and introduce inaccuracies into the radiation therapy treat...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4762814

    authors: Li H,Noel C,Chen H,Harold Li H,Low D,Moore K,Klahr P,Michalski J,Gay HA,Thorstad W,Mutic S

    更新日期:2012-12-01 00:00:00

  • Sci-Fri PM: Planning-03: Fundamental understanding of the inter-relation of arc range, angular dose rate and MLC leaf position optimization of Intensity Modulated Arc Therapy for a concave target.

    abstract::Intensity Modulated Arc Therapy (IMAT) is a rotational variant of Intensity Modulated Radiation Therapy (IMRT) that can be implemented with or without angular dose rate optimization. The purpose of this study is to determine the inter-relationship among arc range, Multi-Leaf Collimator (MLC) leaf positions and angular...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2965975

    authors: Oliver M,Chen J,Wong E

    更新日期:2008-07-01 00:00:00

  • Cumulative sum quality control for calibrated breast density measurements.

    abstract:PURPOSE:Breast density is a significant breast cancer risk factor. Although various methods are used to estimate breast density, there is no standard measurement for this important factor. The authors are developing a breast density standardization method for use in full field digital mammography (FFDM). The approach c...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3250842

    authors: Heine JJ,Cao K,Beam C

    更新日期:2009-12-01 00:00:00

  • On charged particle equilibrium violation in external photon fields.

    abstract:PURPOSE:In a recent paper by Bouchard et al. [Med. Phys. 36(10), 4654-4663 (2009)], a theoretical model of quality correction factors for idealistic so-called plan-class specific reference (PCSR) fields was proposed. The reasoning was founded on the definition of PCSR fields made earlier by Alfonso et al. [Med. Phys. 3...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3684952

    authors: Bouchard H,Seuntjens J,Palmans H

    更新日期:2012-03-01 00:00:00

  • Anniversary paper: Role of medical physicists and the AAPM in improving geometric aspects of treatment accuracy and precision.

    abstract::The last 50 years have seen great advances in the accuracy of external beam radiation therapy. Geometrical uncertainties have been reduced from a centimeter or more in presimulation, skin-mark guided days to 1-2 mm in today's image-guided radiation therapy treatments. Medical physicists, with the support and guidance ...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1118/1.2836420

    authors: Yorke ED,Keall P,Verhaegen F

    更新日期:2008-03-01 00:00:00

  • SU-E-T-622: A Rapid Hybrid VMAT-IMRT Planning Method Using an Abbreviated Beam Angle Optimization Search.

    abstract:PURPOSE:To generate hybrid VMAT-IMRT treatment plans by utilizing an IMRT beam-angle-optimality (BAO) search under a commercially available TPS without the aid of custom optimization software or high performance computing. METHODS:The high dose modulation provided by IMRT beams can be exploited to improve the quality ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735712

    authors: Schulze D,Ionascu D,Tyagi N

    更新日期:2012-06-01 00:00:00

  • Predicting the noise in hybrid (phase and attenuation) x-ray images acquired with the edge illumination technique.

    abstract:PURPOSE:To analyze the noise performance of the edge illumination phase-based x-ray imaging technique when applying "single-shot" phase retrieval. The latter consists in applying a sample-specific low-pass filter to the raw data, leading to "hybrid" images in which phase and attenuation contrast are merged with each ot...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14366

    authors: Hagen CK,Roche I Morgó O,Olivo A

    更新日期:2020-09-01 00:00:00

  • Effect of Contrast Agent Administration on Water Equivalent Diameter in CT.

    abstract:PURPOSE:Water equivalent diameter (WED) is the preferred surrogate for patient size in CT. It is better than geometric size surrogates and patient weight/height/BMI/age because it correlates the best with x-ray attenuation. The administration of oral/IV contrast agents increases a patient's attenuation and should there...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14721

    authors: Viggiano B,Rose S,Szczykutowicz TP

    更新日期:2021-01-13 00:00:00

  • Validation for 2D/3D registration. I: A new gold standard data set.

    abstract:PURPOSE:In this article, the authors propose a new gold standard data set for the validation of two-dimensional/three-dimensional (2D/3D) and 3D/3D image registration algorithms. METHODS:A gold standard data set was produced using a fresh cadaver pig head with attached fiducial markers. The authors used several imagin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3553402

    authors: Pawiro SA,Markelj P,Pernus F,Gendrin C,Figl M,Weber C,Kainberger F,Nöbauer-Huhmann I,Bergmeister H,Stock M,Georg D,Bergmann H,Birkfellner W

    更新日期:2011-03-01 00:00:00

  • SU-E-T-203: Development of a QA Software Tool for Automatic Verification of Plan Data Transfer and Delivery.

    abstract:PURPOSE:Consistency verification between the data from treatment planning system (TPS), record and verification system (R&V), and delivered recorder with visual inspection is time consuming and subject to human error. The purpose of this work is to develop a software tool to automatically perform such verifications. M...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735263

    authors: Chen G,Li X

    更新日期:2012-06-01 00:00:00

  • SU-E-T-145: MRI Gel Dosimetry Applied to Dose Profile Determination for 50kV X-Ray Tube.

    abstract:PURPOSE:The aim of this study was to use MRI gel dosimetry to determine the dose profile of 50kV MAGNUM® X-ray tube, MOXTEK Inc., in order to calibrate small solid dosimeters of alanine, tooth enamel and LiF-TLDs, commonly used in clinical quality assurance and datation dosimetry. METHODS:MAGIC-f polymer gel was kept ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735203

    authors: Schwarcke M,Marques T,Nicolucci P,Filho OB

    更新日期:2012-06-01 00:00:00

  • Controlled mold geometry for surgical deficit treatment planning.

    abstract::The relatively precise placement of brachytherapy sources afforded by stereotactic frames for brain implants is not generally achievable for other sites, which lack the fixed geometry of the cranium and its contents. An exception is a source-containing rigid mold that delivers brachytherapy when inserted securely in a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597454

    authors: Anderson LL,Zlotolow IM,McCormick B,Harrison LB

    更新日期:1995-03-01 00:00:00

  • SU-E-T-424: Inter-Fraction Variation of High Dose Regions of OARS in MR Image Based Cervix Brachytherapy Using Rigid Registration.

    abstract:PURPOSE:To quantify the inter fraction variation of spatial location of high dose regions of OARs in MR-image based cervix brachytherapy using rigid registration algorithm. METHODS:Retrospective analysis of 27 previously treated patients under EMBRACE multi-centric trial was evaluated. Each patient had two application...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735513

    authors: Swamidas J,Mahantshetty U,Deshpande D,Shrivastava S

    更新日期:2012-06-01 00:00:00

  • Innovative methodology for intercomparison of radionuclide calibrators using short half-life in situ prepared radioactive sources.

    abstract:PURPOSE:An original radionuclide calibrator method for activity determination is presented. The method could be used for intercomparison surveys for short half-life radioactive sources used in Nuclear Medicine, such as(99m)Tc or most positron emission tomography radiopharmaceuticals. METHODS:By evaluation of the resul...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4884035

    authors: Oliveira PA,Santos JA

    更新日期:2014-07-01 00:00:00

  • WE-G-BRB-03: On the Detectability of Jaw Decalibrations with the DAVID System.

    abstract:PURPOSE:To evaluate if the recently described problems with the calibration of jaws at Varian linear accelerators can be detected with the DAVID system. METHODS:Recently Varian Clinac field size issues resulted in a widespread medical device correction notice, stating that incorrect jaw positioning due to excessive co...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4736189

    authors: Poppe B,Looe H,Harder D

    更新日期:2012-06-01 00:00:00

  • Technical Note: Imaging dose resulting from optimized procedures with limited-angle intrafractional verification system during stereotactic body radiation therapy lung treatment.

    abstract:PURPOSE:The limited-angle intrafractional verification (LIVE) system was developed to track tumor movement during stereotactic body radiation therapy (SBRT). However, the four-dimensional (4D) MV/kV imaging procedure results in additional radiation dose to patients. This study is to quantify imaging radiation dose from...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13511

    authors: Ding GX,Zhang Y,Ren L

    更新日期:2019-06-01 00:00:00

  • Direct aperture optimization: a turnkey solution for step-and-shoot IMRT.

    abstract::IMRT treatment plans for step-and-shoot delivery have traditionally been produced through the optimization of intensity distributions (or maps) for each beam angle. The optimization step is followed by the application of a leaf-sequencing algorithm that translates each intensity map into a set of deliverable aperture ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1477415

    authors: Shepard DM,Earl MA,Li XA,Naqvi S,Yu C

    更新日期:2002-06-01 00:00:00

  • Sci-Fri AM: Imaging - 05: Cone-beam computed tomography for breast biopsy analysis: Simulations.

    abstract:PURPOSE:To determine the feasibility and potential utility of cone beam CT on breast biopsies. METHODS:CBCT simulations were done with a setup which emulates an MX-20 digital specimen radiography system (Faxitron X-Ray Corporation, Chicago, IL), albeit a DQE = 1 was assumed. The phantom consisted of a 5mm diameter cyl...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4740191

    authors: Laamanen C,LeClair R

    更新日期:2012-07-01 00:00:00

  • Analysis of fractionation correction methodologies for multiple phase treatment plans in radiation therapy.

    abstract:PURPOSE:Radiation therapy is often delivered by multiple sequential treatment plans. For an accurate radiobiological evaluation of the overall treatment, fractionation corrections to each dose distribution must be applied before summing the three-dimensional dose matrix of each plan since the simpler approach of perfor...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4792636

    authors: Mavroidis P,Ferreira BC,Papanikolaou N,Lopes Mdo C

    更新日期:2013-03-01 00:00:00

  • Establishment of technical prerequisites for cell irradiation experiments with laser-accelerated electrons.

    abstract:PURPOSE:In recent years, laser-based acceleration of charged particles has rapidly progressed and medical applications, e.g., in radiotherapy, might become feasible in the coming decade. Requirements are monoenergetic particle beams with long-term stable and reproducible properties as well as sufficient particle intens...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3301598

    authors: Beyreuther E,Enghardt W,Kaluza M,Karsch L,Laschinsky L,Lessmann E,Nicolai M,Pawelke J,Richter C,Sauerbrey R,Schlenvoigt HP,Baumann M

    更新日期:2010-04-01 00:00:00

  • VMAT and IMRT plan-specific correction factors for linac-based ionization chamber dosimetry.

    abstract:PURPOSE:The determination of absorbed dose to water from external beam radiotherapy using radiation detectors is currently rooted in calibration protocols that do not account for modulations encountered in patient-specific deliveries. Detector response in composite clinical fields has not been extensively studied due t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13293

    authors: Desai VK,Labby ZE,Hyun MA,DeWerd LA,Culberson WS

    更新日期:2019-02-01 00:00:00

  • Effect of surrounding vasculature on intravoxel BOLD signal.

    abstract:PURPOSE:The nonlocal influence from distant magnetization will affect the magnetic field at a voxel in question. Existing reports on BOLD simulation only consider vasculature inside a single voxel, thus omitting the contribution from the surrounding regions. In this article, the authors study the effect of the surround...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3366251

    authors: Chen Z,Caprihan A,Calhoun V

    更新日期:2010-04-01 00:00:00