The DosiMap, a new 2D scintillating dosimeter for IMRT quality assurance: characterization of two Cerenkov discrimination methods.

Abstract:

:New radiation therapy techniques such as IMRT present significant efficiency due to their highly conformal dose distributions. A consequence of the complexity of their dose distributions (high gradients, small irradiation fields, low dose distribution, ...) is the requirement for better precision quality assurance than in classical radiotherapy in order to compare the conformation of the delivered dose with the planned dose distribution and to guarantee the quality of the treatment. Currently this control is mostly performed by matrices of ionization chambers, diode detectors, dosimetric films, portal imaging, or dosimetric gels. Another approach is scintillation dosimetry, which has been developed in the last 15 years mainly through scintillating fiber devices. Despite having many advantages over other methods it is still at an experimental level for routine dosimetry because the Cerenkov radiation produced under irradiation represents an important stem effect. A new 2D water equivalent scintillating dosimeter, the DosiMap, and two different Cerenkov discrimination methods were developed with the collaboration of the Laboratoire de Physique Corpusculaire of Caen, the Comprehensive Cancer Center François Baclesse, and the ELDIM Co., in the frame of the MAESTRO European project. The DosiMap consists of a plastic scintillating sheet placed inside a transparent polystyrene phantom. The light distribution produced under irradiation is recorded by a CCD camera. Our first Cerenkov discrimination technique is subtractive. It uses a chessboard pattern placed in front of the scintillator, which provides a background signal containing only Cerenkov light. Our second discrimination technique is colorimetric. It performs a spectral analysis of the light signal, which allows the unfolding of the Cerenkov radiation and the scintillation. Tests were carried out with our DosiMap prototype and the performances of the two discrimination methods were assessed. The comparison of the dose measurements performed with the DosiMap and with dosimetric films for three different irradiation configurations showed discrepancies smaller than 3.5% for a 2 mm spatial resolution. Two innovative discrimination solutions were demonstrated to separate the scintillation from the Cerenkov radiation. It was also shown that the DosiMap, which is water equivalent, fast, and user friendly, is a very promising tool for radiotherapy quality assurance.

journal_name

Med Phys

journal_title

Medical physics

authors

Frelin AM,Fontbonne JM,Ban G,Colin J,Labalme M,Batalla A,Vela A,Boher P,Braud M,Leroux T

doi

10.1118/1.2897966

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

1651-62

issue

5

eissn

0094-2405

issn

2473-4209

journal_volume

35

pub_type

杂志文章
  • Dose sculpting with generalized equivalent uniform dose.

    abstract::With intensity-modulated radiotherapy (IMRT), a variety of user-defined dose distribution can be produced using inverse planning. The generalized equivalent uniform dose (gEUD) has been used in IMRT optimization as an alternative objective function to the conventional dose-volume-based criteria. The purpose of this st...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1897464

    authors: Wu Q,Djajaputra D,Liu HH,Dong L,Mohan R,Wu Y

    更新日期:2005-05-01 00:00:00

  • Monte Carlo study of ionization chamber magnetic field correction factors as a function of angle and beam quality.

    abstract:PURPOSE:To use EGSnrc Monte Carlo simulations for magnetic field dosimetry to determine optimal measurement orientations, calculate beam quality conversion factors for 32 cylindrical and three parallel-plate (PP) ion chambers, evaluate the beam quality and angular dependence of these factors, and examine the magnetic f...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12716

    authors: Malkov VN,Rogers DWO

    更新日期:2018-02-01 00:00:00

  • Matching photon and electron fields with dynamic intensity modulation.

    abstract::A technique was developed to reduce the size and magnitude of the hot and cold spots in the abutting regions of photon and electron fields. The photon and electron fields were set up such that the photon field extended approximately 2 cm into the electron field in the abutting region. The region of the photon beam tha...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598753

    authors: Li JG,Xing L,Boyer AL,Hamilton RJ,Spelbring DR,Turian JV

    更新日期:1999-11-01 00:00:00

  • Assessment of image registration accuracy in three-dimensional transrectal ultrasound guided prostate biopsy.

    abstract:PURPOSE:Prostate biopsy, performed using two-dimensional (2D) transrectal ultrasound (TRUS) guidance, is the clinical standard for a definitive diagnosis of prostate cancer. Histological analysis of the biopsies can reveal cancerous, noncancerous, or suspicious, possibly precancerous, tissue. During subsequent biopsy s...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3298010

    authors: Karnik VV,Fenster A,Bax J,Cool DW,Gardi L,Gyacskov I,Romagnoli C,Ward AD

    更新日期:2010-02-01 00:00:00

  • An alternative VMAT with prior knowledge about the type of leaf motion utilizing projection method for concave targets.

    abstract::The authors present an alternative approach to inverse planning optimization and apply it to volumetric modulated are therapy (VMAT) in one rotation with a prior knowledge about the type of leaf motions. The optimization is based on the projection theorem in inner product spaces. MLC motion is directly considered in t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3173815

    authors: Hoegele W,Loeschel R,Zygmanski P

    更新日期:2009-08-01 00:00:00

  • Evaluation of carbon nanotube x-ray source array for stationary head computed tomography.

    abstract:PURPOSE:Stationary computed tomography (s-CT) conceptually offers several advantages over existing rotating gantry-based CT. Over the last 40 yr, s-CT has been investigated using different technological approaches. We are developing a s-CT system specifically for head/brain imaging using carbon nanotube (CNT)-based fie...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14696

    authors: Spronk D,Luo Y,Inscoe CR,Lee YZ,Lu J,Zhou O

    更新日期:2020-12-31 00:00:00

  • X-ray imaging with amorphous selenium: X-ray to charge conversion gain and avalanche multiplication gain.

    abstract::Fluoroscopy is a low dose imaging technique. As such, a very sensitive detector is required to create images of good quality. Present day flat panel active matrix read out systems introduce an amount of noise that inhibits present direct and indirect methods from producing optimal quality images at fluoroscopic exposu...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1513157

    authors: Hunt DC,Kirby SS,Rowlands JA

    更新日期:2002-11-01 00:00:00

  • A K alpha dual energy x-ray source for coronary angiography.

    abstract::The use of characteristic-line radiation from rare-earth targets bombarded by high-energy (up to 1 MeV) electron beams has been evaluated as an x-ray source for dual energy K-edge subtraction imaging of the human coronary arteries. Two characteristic-line x-ray sources, one using the split K alpha 1 and K alpha 2 line...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596648

    authors: Manning HL,Shefer RE,Klinkowstein RE,Mistretta CA

    更新日期:1991-09-01 00:00:00

  • A practical technique for verification of three-dimensional conformal dose distributions in stereotactic radiosurgery.

    abstract::The trend toward conformal techniques in stereotactic radiosurgery necessitates an accurate and practical method for verification of irregular three-dimensional dose distributions. This work presents the design and evaluation of a phantom system facilitating the measurement of conformal dose distributions using one or...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598962

    authors: Robar JL,Clark BG

    更新日期:2000-05-01 00:00:00

  • Design and experimental testing of air slab caps which convert commercial electron diodes into dual purpose, correction-free diodes for small field dosimetry.

    abstract:PURPOSE:Two diodes which do not require correction factors for small field relative output measurements are designed and validated using experimental methodology. This was achieved by adding an air layer above the active volume of the diode detectors, which canceled out the increase in response of the diodes in small f...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4894728

    authors: Charles PH,Cranmer-Sargison G,Thwaites DI,Kairn T,Crowe SB,Pedrazzini G,Aland T,Kenny J,Langton CM,Trapp JV

    更新日期:2014-10-01 00:00:00

  • A strategy to decrease partial scan reconstruction artifacts in myocardial perfusion CT: phantom and in vivo evaluation.

    abstract:PURPOSE:Partial scan reconstruction (PSR) artifacts are present in myocardial perfusion imaging using dynamic multidetector computed tomography (MDCT). PSR artifacts appear as temporal CT number variations due to inconsistencies in the angular data range used to reconstruct images and compromise the quantitative value ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3665767

    authors: Ramirez-Giraldo JC,Yu L,Kantor B,Ritman EL,McCollough CH

    更新日期:2012-01-01 00:00:00

  • Prostatome: a combined anatomical and disease based MRI atlas of the prostate.

    abstract:PURPOSE:In this work, the authors introduce a novel framework, the anatomically constrained registration (AnCoR) scheme and apply it to create a fused anatomic-disease atlas of the prostate which the authors refer to as the prostatome. The prostatome combines a MRI based anatomic and a histology based disease atlas. St...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4881515

    authors: Rusu M,Bloch BN,Jaffe CC,Genega EM,Lenkinski RE,Rofsky NM,Feleppa E,Madabhushi A

    更新日期:2014-07-01 00:00:00

  • Theoretical investigation of the count rate capabilities of in-pixel amplifiers for photon counting arrays based on polycrystalline silicon TFTs.

    abstract:PURPOSE:Photon counting arrays (PCAs), capable of measuring the spectral information of individual x-ray photons and recording that information digitally, provide a number of advantages compared to conventional, energy-integrating active matrix flat-panel imagers - such as reducing the undesirable effects of electronic...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13128

    authors: Liang AK,Koniczek M,Antonuk LE,El-Mohri Y,Zhao Q

    更新日期:2018-10-01 00:00:00

  • Investigation of a breathing surrogate prediction algorithm for prospective pulmonary gating.

    abstract:PURPOSE:A major challenge of four dimensional computed tomography (4DCT) in treatment planning and delivery has been the lack of respiration amplitude and phase reproducibility during image acquisition. The implementation of a prospective gating algorithm would ensure that images would be acquired only during user-spec...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3556589

    authors: White BM,Low DA,Zhao T,Wuenschel S,Lu W,Lamb JM,Mutic S,Bradley JD,El Naqa I

    更新日期:2011-03-01 00:00:00

  • Absolute diameter measurements of coronary arteries based on the first zero crossing of the Fourier spectrum.

    abstract::Current edge detection methods used to determine coronary artery dimensions from digital (DSA) images suffer a strong dependence on the system's modulation transfer function (MTF). The videodensitometric algorithms are less sensitive to MTF blurring, yet still result in an overestimation of the vessel size of 10% to 2...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596370

    authors: Weber DM

    更新日期:1989-03-01 00:00:00

  • Potential use of P-32 ophthalmic applicator: Monte Carlo simulations for design and dosimetry.

    abstract::Postoperative beta-irradiation after pterygium excision has been considered a valuable therapeutic procedure to reduce the recurrence rate. Recently, it was reported that beta-irradiation also substantially reduced the risk of surgical failure after glaucoma surgery. Pure beta-irradiation using a 90Sr/Y applicator has...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2896076

    authors: Park YK,Ye SJ,Kim IH,Wee WR,Kim MK,Han HS,Son KJ,Park UJ

    更新日期:2008-05-01 00:00:00

  • Lung dosimetry in a linac-MRI radiotherapy unit with a longitudinal magnetic field.

    abstract:PURPOSE:There is interest in developing linac-MR systems for MRI-guided radiation therapy. To date, the designs for such linac-MR devices have been restricted to a transverse geometry where the static magnetic field is oriented perpendicular to the direction of the incident photon beam. This work extends possibilities ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3475942

    authors: Kirkby C,Murray B,Rathee S,Fallone BG

    更新日期:2010-09-01 00:00:00

  • Detecting electron beam energy shifts with a commercially available energy monitor.

    abstract::Routine electron beam quality assurance requires an accurate, yet practical, method of energy characterization. Subtle shifts in beam energy may be produced by the linac bending magnet assembly, and the sensitivity of a commercially available electron beam energy-monitoring device for monitoring these small energy dri...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.599033

    authors: Evans MD,Moftah BA,Olivares M,Podgorsak EB

    更新日期:2000-07-01 00:00:00

  • Objective performance characteristics of a new asymmetric screen-film system.

    abstract::A study of the objective imaging characteristics of a new asymmetric screen-film system is presented herein. The system is characterized by high x-ray absorption asymmetric screens, and a low-noise, high-contrast asymmetric film having near-zero crossover. Comparisons are made with the imaging characteristics of two w...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597407

    authors: Van Metter R,Dickerson R

    更新日期:1994-09-01 00:00:00

  • SU-E-T-144: Daily and Monthly Quality Assurance with TomoDose.

    abstract:PURPOSE:Examine the use of TomoDose for Tomotherapy quality assurance. METHODS:Baseline TomoDose profiles are acquired annually in accordance with TG-148. During monthly quality assurance, TomoDose is irradiated with a static beam and referenced to baseline. Differences between superimposed profiles are evaluated mont...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735202

    authors: Terrell J

    更新日期:2012-06-01 00:00:00

  • SU-E-T-429: Image-Guided Eye Plaque Brachytherapy Optimization: Implications for Patients at 2-Year Follow-up.

    abstract:PURPOSE:Episcleral eye plaque brachytherapy has been utilized in the treatment of intra-ocular malignancies, delivering large prescription doses to the apex of the tumor. Advances in dose calculation and image guidance, via calibrated fundus images, enable localization of the tumor and determination of dose to the macu...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735518

    authors: Guida K,Niermann K,Malcolm A,Sternberg P,Munn G,Coffey C

    更新日期:2012-06-01 00:00:00

  • The influence of field strength and different clinical breast MRI protocols on the outcome of texture analysis using foam phantoms.

    abstract:PURPOSE:Texture analysis (TA) has proved to be useful to distinguish different tissues and disease states using magnetic resonance imaging (MRI). TA has been successfully applied clinically to improve identification of abnormalities in the brain, liver, and bone and, more recently, has been used to enhance the specific...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3622605

    authors: Waugh SA,Lerski RA,Bidaut L,Thompson AM

    更新日期:2011-09-01 00:00:00

  • Absolute x-ray dosimetry on a synchrotron medical beam line with a graphite calorimeter.

    abstract:PURPOSE:The absolute dose rate of the Imaging and Medical Beamline (IMBL) on the Australian Synchrotron was measured with a graphite calorimeter. The calorimetry results were compared to measurements from the existing free-air chamber, to provide a robust determination of the absolute dose in the synchrotron beam and p...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4870387

    authors: Harty PD,Lye JE,Ramanathan G,Butler DJ,Hall CJ,Stevenson AW,Johnston PN

    更新日期:2014-05-01 00:00:00

  • A dual cone-beam CT system for image guided radiotherapy: initial performance characterization.

    abstract:PURPOSE:The purpose of this study is to evaluate the performance of a recently developed benchtop dual cone-beam computed tomography (CBCT) system with two orthogonally placed tube∕detector sets. METHODS:The benchtop dual CBCT system consists of two orthogonally placed 40 × 30 cm flat-panel detectors and two conventio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4788654

    authors: Li H,Giles W,Bowsher J,Yin FF

    更新日期:2013-02-01 00:00:00

  • A technical solution to avoid partial scan artifacts in cardiac MDCT.

    abstract::Quantitative evaluation of cardiac image data obtained using multidetector row computed tomography (CT) is compromised by partial scan reconstructions, which improve the temporal resolution but significantly increase image-to-image CT number variations for a fixed region of interest compared to full reconstruction ima...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2805476

    authors: Primak AN,Dong Y,Dzyubak OP,Jorgensen SM,McCollough CH,Ritman EL

    更新日期:2007-12-01 00:00:00

  • Comparison of measured with calculated dose distribution from a 120-MeV electron beam from a laser-plasma accelerator.

    abstract:PURPOSE:To evaluate the dose distribution of a 120-MeV laser-plasma accelerated electron beam which may be of potential interest for high-energy electron radiation therapy. METHODS:In the interaction between an intense laser pulse and a helium gas jet, a well collimated electron beam with very high energy is produced....

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4719962

    authors: Lundh O,Rechatin C,Faure J,Ben-Ismaïl A,Lim J,De Wagter C,De Neve W,Malka V

    更新日期:2012-06-01 00:00:00

  • Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models.

    abstract:PURPOSE:Computational models of microwave tissue ablation are widely used to guide the development of ablation devices, and are increasingly being used for the development of treatment planning and monitoring platforms. Knowledge of temperature-dependent dielectric properties of lung tissue is essential for accurate mo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13704

    authors: Sebek J,Bortel R,Prakash P

    更新日期:2019-10-01 00:00:00

  • Real-time distortionless high-factor compression scheme.

    abstract::Nowadays, digital subtraction angiography systems must be able to sustain real-time acquisition (30 frames per second) of 512 x 512 x 8 bit images and store several sequences of such images on low cost and general-purpose mass memories. Concretely, that means a 7.8 Mbytes per second rate and about 780 Mbytes disk spac...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596309

    authors: Liénard J

    更新日期:1989-11-01 00:00:00

  • Dose distributions around cylindrical 241Am sources for a clinical intracavitary applicator.

    abstract::Encapsulated, cylindrical sources containing 2, 5, and 8 Ci of 241Am have been designed and fabricated for intracavitary irradiation of uterine cancers. Exposure rates in air and dose rates in water around these sources have been measured using an ionization chamber and a lithium fluoride thermoluminescent dosimetry s...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596007

    authors: Nath R,Gray L,Park CH

    更新日期:1987-09-01 00:00:00

  • Direct-response ultraviolet thermoluminescent dosimeter.

    abstract::An integrating solid-state dosimeter has been developed to detect ultraviolet radiation using the process of "direct" ultraviolet stimulation. This process yields a thermoluminescent signal after an exposure to ultraviolet radiation, without prior exposure to ionizing radiation. Magnesium oxide crystals were found to ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594259

    authors: Dhar A,DeWerd LA,Stoebe TG

    更新日期:1976-11-01 00:00:00