An accurate method for direct dual-energy calibration and decomposition.

Abstract:

:We propose the use of conic and cubic surface equations (surfaces of second and third order) to directly approximate the dual-energy equations (the integral equations for the dual-energy log-signal functions, i.e., the negative logarithms of the relative detector signals, considered as functions of the basis-material component thicknesses of the object) and especially their inverses. These types of surface equations require a minimum number of calibration points, and their solutions are smooth, monotonic functions with the correct linear asymptotic behavior. The accuracy of this method is investigated and compared to that of conventional polynomial approximations, both for simulated and real calibration data, taken from two split-detector systems. These systems provide a more stringent test of our method than comparable dual-kVp systems, due to the greater nonlinearity of their log-signal and inverse functions. For these systems, we show that direct approximation of the inverse dual-energy equations using the simple eight-term rational form of the conic surface equation provides an extremely fast decomposition algorithm, which is accurate, robust in the presence of noise, and which can be calibrated with as few as 9 calibration points, or robustly calibrated, with a built-in accuracy check, using only 16 calibration points. Also, we show that extreme accuracy of approximation (to within less than 10(-6) in log-signal and 1 micron in material thickness) is theoretically attainable using the eighteen-term form of the cubic surface equation, which has a closed-form analytic solution. Finally, we consider the effects of noise on calibration accuracy, and derive simple formulas which relate the true and apparent root-mean-square (rms) accuracies. These formulas then allow the comparison of the true rms calibration accuracies of various surface approximations, considered as functions of the total calibration heat loading of the x-ray tube.

journal_name

Med Phys

journal_title

Medical physics

authors

Cardinal HN,Fenster A

doi

10.1118/1.596512

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

327-41

issue

3

eissn

0094-2405

issn

2473-4209

journal_volume

17

pub_type

杂志文章
  • Technical Note: Measuring contrast- and noise-dependent spatial resolution of an iterative reconstruction method in CT using ensemble averaging.

    abstract:PURPOSE:The spatial resolution of iterative reconstruction (IR) in computed tomography (CT) is contrast- and noise-dependent because of the nonlinear regularization. Due to the severe noise contamination, it is challenging to perform precise spatial-resolution measurements at very low-contrast levels. The purpose of th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4916802

    authors: Yu L,Vrieze TJ,Leng S,Fletcher JG,McCollough CH

    更新日期:2015-05-01 00:00:00

  • Development and clinical evaluation of an ionization chamber array with 3.5 mm pixel pitch for quality assurance in advanced radiotherapy techniques.

    abstract:PURPOSE:To characterize a new air vented ionization chamber technology, suitable to build detector arrays with small pixel pitch and independence of sensitivity on dose per pulse. METHODS:The prototype under test is a linear array of air vented ionization chambers, consisting of 80 pixels with 3.5 mm pixel pitch dista...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4945414

    authors: Togno M,Wilkens JJ,Menichelli D,Oechsner M,Perez-Andujar A,Morin O

    更新日期:2016-05-01 00:00:00

  • Computerized detection of lung nodules through radiomics.

    abstract:PURPOSE:Lung cancer is a major cause of cancer deaths, and the 5-year survival rate of stage IV lung cancer patients is only 2%. However, the 5-year survival rate of stage I lung cancer patients significantly increases to 50%. As such, spiral computed tomography (CT) scans are necessary to diagnose high-risk lung cance...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12331

    authors: Ma J,Zhou Z,Ren Y,Xiong J,Fu L,Wang Q,Zhao J

    更新日期:2017-08-01 00:00:00

  • Large field of view distortion assessment in a low-field MR-linac.

    abstract:PURPOSE:MR-guided radiation therapy (RT) offers unparalleled soft tissue contrast for localization and target tracking. However, MRI distortions may be detrimental to high precision RT. This work characterizes the gradient nonlinearity (GNL) and total distortions over the first year of clinical operation of a 0.35T MR-...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13467

    authors: Nejad-Davarani SP,Kim JP,Du D,Glide-Hurst C

    更新日期:2019-05-01 00:00:00

  • A phantom for visualization of three-dimensional drug release by ultrasound-induced mild hyperthermia.

    abstract:PURPOSE:Ultrasound-induced mild hyperthermia has advantages for noninvasive, localized and controlled drug delivery. In this study, a tissue-mimicking agarose-based phantom with a thermally sensitive indicator was developed for studying the spatial drug delivery profile using ultrasound-induced mild hyperthermia. METH...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4813299

    authors: Lai CY,Kruse D,Seo JW,Kheirolomoom A,Ferrara KW

    更新日期:2013-08-01 00:00:00

  • Tight-frame based iterative image reconstruction for spectral breast CT.

    abstract:PURPOSE:To investigate tight-frame based iterative reconstruction (TFIR) technique for spectral breast computed tomography (CT) using fewer projections while achieving greater image quality. METHODS:The experimental data were acquired with a fan-beam breast CT system based on a cadmium zinc telluride photon-counting d...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4790468

    authors: Zhao B,Gao H,Ding H,Molloi S

    更新日期:2013-03-01 00:00:00

  • Beam properties and stability of a flattening-filter free 7 MV beam-an overview.

    abstract:PURPOSE:Several works have recently focused on flattening-filter-free (FFF) beams of linear accelerators of various companies (in particular, Varian and Elekta), but no overview as yet exists for the flattening-filter free 7XU beam (Siemens Artiste). METHODS:Dosimetric properties of the 7XU beam were measured in May a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3703835

    authors: Dzierma Y,Licht N,Nuesken F,Ruebe C

    更新日期:2012-05-01 00:00:00

  • SU-E-T-590: Procedure for Verification and Inter-Comparison of IMRT Beam Models.

    abstract:PURPOSE:The implementation of an accurate beam model is an integral part of the commissioning of any planning system. This process is especially challenging in the case of IMRT beam models owing to the complexity of small field sizes and MLC leaf-end and tongue-and-groove effects. The question of how to judge the quali...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735679

    authors: Veltchev I,Fourkal E,Price R,Ma C

    更新日期:2012-06-01 00:00:00

  • Integrating prior information into microwave tomography Part 1: Impact of detail on image quality.

    abstract:PURPOSE:The authors investigate the impact that incremental increases in the level of detail of patient-specific prior information have on image quality and the convergence behavior of an inversion algorithm in the context of near-field microwave breast imaging. A methodology is presented that uses image quality measur...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12585

    authors: Kurrant D,Baran A,LoVetri J,Fear E

    更新日期:2017-12-01 00:00:00

  • Brain SPECT with short focal-length cone-beam collimation.

    abstract::Single-photon emission-computed tomography (SPECT) imaging of deep brain structures is compromised by loss of photons due to attenuation. We have previously shown that a centrally peaked collimator sensitivity function can compensate for this phenomenon, increasing sensitivity over most of the brain. For dual-head ins...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1929208

    authors: Park MA,Moore SC,Kijewski MF

    更新日期:2005-07-01 00:00:00

  • Directional scatter imaging for the stereoscopic tracking of fiducial markers in a single kV exposure.

    abstract:PURPOSE:To demonstrate, via Monte Carlo simulation, that an image obtained from the patient-generated scattered radiation forced to impinge on the detector from a known direction by means of parallel-focused grids, can be used to complement the information conveyed by the primary image, such that accurate stereoscopic ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12712

    authors: Garnica-Garza HM

    更新日期:2018-02-01 00:00:00

  • Superiorization: an optimization heuristic for medical physics.

    abstract:PURPOSE:To describe and mathematically validate the superiorization methodology, which is a recently developed heuristic approach to optimization, and to discuss its applicability to medical physics problem formulations that specify the desired solution (of physically given or otherwise obtained constraints) by an opti...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4745566

    authors: Herman GT,Garduno E,Davidi R,Censor Y

    更新日期:2012-09-01 00:00:00

  • Quantitative cone-beam CT imaging in radiation therapy using planning CT as a prior: first patient studies.

    abstract:PURPOSE:Quantitative cone-beam CT (CBCT) imaging is on increasing demand for high-performance image guided radiation therapy (IGRT). However, the current CBCT has poor image qualities mainly due to scatter contamination. Its current clinical application is therefore limited to patient setup based on only bony structure...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3693050

    authors: Niu T,Al-Basheer A,Zhu L

    更新日期:2012-04-01 00:00:00

  • Eddy current disruption: effect on nuclear magnetic resonance coil impedance and power loss.

    abstract::We present a theoretical development and experimental verification of a description of power loss and sample resistance for a lossy sample in a nuclear magnetic resonance radio frequency coil for a sample geometry where the eddy current streamlines are disrupted from their usually assumed circular paths. Specifically ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596336

    authors: Harpen MD

    更新日期:1989-09-01 00:00:00

  • Characteristics and quality assurance of a dedicated open 0.23 T MRI for radiation therapy simulation.

    abstract::A commercially available open MRI unit is under routine use for radiation therapy simulation. The effects of a gradient distortion correction (GDC) program used to post process the images were assessed by comparison with the known geometry of a phantom. The GDC reduced the magnitude of the distortions at the periphery...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1513991

    authors: Mah D,Steckner M,Palacio E,Mitra R,Richardson T,Hanks GE

    更新日期:2002-11-01 00:00:00

  • Demonstration of megavoltage and diagnostic x-ray imaging with hydrogenated amorphous silicon arrays.

    abstract::Flat-panel imagers consisting of the first large area, self-scanning, pixelated, solid-state arrays made with hydrogenated amorphous silicon (a-Si:H) are under development by the authors for applications in diagnostic x-ray and megavoltage radiotherapy imaging. The arrays, designated by the acronym MASDA for multi-ele...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596802

    authors: Antonuk LE,Boudry J,Huang W,McShan DL,Morton EJ,Yorkston J,Longo MJ,Street RA

    更新日期:1992-11-01 00:00:00

  • Dead time of an anger camera in dual-energy-window-acquisition mode.

    abstract::Two side-by-side energy windows are sometimes employed in quantitative single photon emission computed tomography (SPECT) studies. The count-rate losses at high activities for a GE400AT camera were measured in such a dual-window-acquisition mode by imaging a decaying source composed of a hot sphere within a warm cylin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597008

    authors: Zasadny KR,Koral KF,Swailem FM

    更新日期:1993-07-01 00:00:00

  • Design, development, and implementation of the radiological physics center's pelvis and thorax anthropomorphic quality assurance phantoms.

    abstract::The Radiological Physics Center (RPC) developed two heterogeneous anthropomorphic quality assurance phantoms for use in verifying the accuracy of radiation delivery: one for intensity-modulated radiation therapy (IMRT) to the pelvis and the other for stereotactic body radiation therapy (SBRT) to the thorax. The purpos...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2737158

    authors: Followill DS,Evans DR,Cherry C,Molineu A,Fisher G,Hanson WF,Ibbott GS

    更新日期:2007-06-01 00:00:00

  • Ray-based approach to skeletal muscle perfusion measurement on interventional x-ray systems.

    abstract:PURPOSE:Periprocedural assessment of tissue perfusion by imaging methods could improve outcome control during treatment of peripheral vascular disease. Currently, endovascular revascularization treatments are assessed by planar angiography which only allows for qualitative inspection of blood flow in vessels. In this p...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3679864

    authors: Giordano M,Vonken EJ,Bertram M,Mali W,Viergever MA,Neukirchen C

    更新日期:2012-03-01 00:00:00

  • Investigation of effective decision criteria for multiobjective optimization in IMRT.

    abstract:PURPOSE:To investigate how using different sets of decision criteria impacts the quality of intensity modulated radiation therapy (IMRT) plans obtained by multiobjective optimization. METHODS:A multiobjective optimization evolutionary algorithm (MOEA) was used to produce sets of IMRT plans. The MOEA consisted of two i...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3589128

    authors: Holdsworth C,Stewart RD,Kim M,Liao J,Phillips MH

    更新日期:2011-06-01 00:00:00

  • Absorbed dose in the presence of contrast agents during pediatric cardiac catheterization.

    abstract::Administration of x-ray contrast agents during heart catheterization examination increases the absorbed radiation dose in tissue. To estimate the dose absorbed by the blood of children undergoing diagnostic heart catheterization and angiocardiography, a number of measurements and calculations were conducted. First, en...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594613

    authors: Callisen HH,Norman A,Adams FH

    更新日期:1979-11-01 00:00:00

  • Proliferative diabetic retinopathy characterization based on fractal features: Evaluation on a publicly available dataset.

    abstract:PURPOSE:Diabetic retinopathy (DR) is one of the most widespread causes of preventable blindness in the world. The most dangerous stage of this condition is proliferative DR (PDR), in which the risk of vision loss is high and treatments are less effective. Fractal features of the retinal vasculature have been previously...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12627

    authors: Orlando JI,van Keer K,Barbosa Breda J,Manterola HL,Blaschko MB,Clausse A

    更新日期:2017-12-01 00:00:00

  • Improvement of off-axis SABR plan verification results by using adapted dose reconstruction algorithms for the Octavius 4D system.

    abstract:PURPOSE:Stereotactic ablative body radiotherapy (SABR) for lung patients can be performed with volumetric-modulated arc therapy (VMAT) plans using off-axis target geometry to allow treatment in their CBCT verified position. For patient-specific quality assurance measurements using the PTW Octavius 4D phantom (PTW, Frei...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12805

    authors: Jeevanandam P,Agnew CE,Irvine DM,McGarry CK

    更新日期:2018-04-01 00:00:00

  • WE-G-BRB-03: On the Detectability of Jaw Decalibrations with the DAVID System.

    abstract:PURPOSE:To evaluate if the recently described problems with the calibration of jaws at Varian linear accelerators can be detected with the DAVID system. METHODS:Recently Varian Clinac field size issues resulted in a widespread medical device correction notice, stating that incorrect jaw positioning due to excessive co...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4736189

    authors: Poppe B,Looe H,Harder D

    更新日期:2012-06-01 00:00:00

  • Evaluation of edge effect due to phase contrast imaging for mammography.

    abstract::It is well-known that the edge effect produced by phase contrast imaging results in the edge enhancement of x-ray images and thereby sharpens those images. It has recently been reported that phase contrast imaging using practical x-ray tubes with small focal spots has improved image sharpness as observed in the phase ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1992087

    authors: Matsuo S,Katafuchi T,Tohyama K,Morishita J,Yamada K,Fujita H

    更新日期:2005-08-01 00:00:00

  • Quantification with a dedicated breast PET/CT scanner.

    abstract:PURPOSE:Dedicated breast PET/CT is expected to have utility in local staging, surgical planning, monitoring of therapy response, and detection of residual disease for breast cancer. Quantitative metrics will be integral to several such applications. The authors present a validation of fully 3D data correction schemes f...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3703593

    authors: Bowen SL,Ferrero A,Badawi RD

    更新日期:2012-05-01 00:00:00

  • Reconstruction of electron spectra using singular component decomposition.

    abstract::Reconstruction of electron spectra of medical accelerators from measured depth dose distributions is an attractive tool for commissioning of a Monte Carlo treatment planning system. However, the reconstruction method is an inverse radiation transport problem which is poorly conditioned, in the sense it may become unst...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1461840

    authors: Chvetsov AV,Sandison GA

    更新日期:2002-04-01 00:00:00

  • Clinical use of EBT model Gafchromic film in radiotherapy.

    abstract::The Gafchromic EBT was recently introduced in film dosimetry for external beam therapy (EBT). The high spatial resolution, weak energy dependence, and near-tissue equivalence of EBT films make them suitable for measurement of dose distributions in radiotherapy, especially intensity-modulated radiation therapy (IMRT). ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2362876

    authors: Fiandra C,Ricardi U,Ragona R,Anglesio S,Giglioli FR,Calamia E,Lucio F

    更新日期:2006-11-01 00:00:00

  • Dynamic multiatlas selection-based consensus segmentation of head and neck structures from CT images.

    abstract:PURPOSE:Manual delineation of head and neck (H&N) organ-at-risk (OAR) structures for radiation therapy planning is time consuming and highly variable. Therefore, we developed a dynamic multiatlas selection-based approach for fast and reproducible segmentation. METHODS:Our approach dynamically selects and weights the a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13854

    authors: Haq R,Berry SL,Deasy JO,Hunt M,Veeraraghavan H

    更新日期:2019-12-01 00:00:00

  • A method for determining multileaf collimator transmission and scatter for dynamic intensity modulated radiotherapy.

    abstract::The main purpose of this work is to demonstrate a practical means of determining the leaf transmission and scatter characteristics of a multileaf collimator (MLC) pertinent to the commissioning of dynamic intensity modulated radiotherapy, especially for the sweeping window technique. The data are necessary for the con...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1312190

    authors: Arnfield MR,Siebers JV,Kim JO,Wu Q,Keall PJ,Mohan R

    更新日期:2000-10-01 00:00:00