DNA-nanoparticle interactions: Formation of a DNA corona and its effects on a protein corona.

abstract：:Collecting information at the interface between living cells and artificial substrates is exceedingly difficult. The extracellular matrix (ECM) mediates all cell-substrate interactions, and its ordered, fibrillar constituents are organized with nanometer precision. The proceedings at this interface are highly dynamic ...

journal_title：Biointerphases

authors： Diesner MO,Welle A,Kazanci M,Kaiser P,Spatz J,Koelsch P

更新日期：2011-12-01 00:00:00

abstract：:The vascular endothelial cells (EC) extracellular matrix (ECM) on the biomaterial surface can significantly improve the blood compatibility and cell compatibility of the cardiovascular materials. In the present study, two types of micropatterned TiO2 nanotubes surfaces (gronano and toponano) were fabricated on the tit...

journal_title：Biointerphases

authors： Wu J,Li J,Wu F,He Z,Yang P,Huang N

更新日期：2015-12-17 00:00:00

abstract：:Understanding how platelet activation is regulated is important in the context of cardiovascular disorders and their management with antiplatelet therapy. Recent evidence points to different platelet subpopulations performing different functions. In particular, procoagulant and aggregating subpopulations have been rep...

journal_title：Biointerphases

authors： Donati A,Gupta S,Reviakine I

更新日期：2016-06-22 00:00:00

abstract：:Mucus is a viscous slime that plays a vital role in protecting and lubricating biological tissues, in particular, soft epithelium interfaces such as in the stomach, intestines, and esophagus. Previous attempts to generate mucus models that mimick or simulate its characteristics have been predominantly focused on the r...

journal_title：Biointerphases

authors： Røn T,Patil NJ,Ajalloueian F,Rishikesan S,Zappone B,Chronakis IS,Lee S

更新日期：2017-12-05 00:00:00

abstract：:Understanding how topographical cues can control cell behavior is a major fundamental question which is of particular interest for implant design. Recent findings show that cell-scale curvature, as well as nanoscale topography, can affect different aspects of cell migration. However, the correlation between specific c...

journal_title：Biointerphases

authors： Belaud V,Petithory T,Ponche A,Mauclair C,Donnet C,Pieuchot L,Benayoun S,Anselme K

更新日期：2018-12-31 00:00:00

abstract：:Although protein-stabilized gold nanoclusters (AuNCs) have gathered recent attention as biocompatible peroxidase mimics, their practical utility has been critically limited by the low catalytic activity. Here, the authors have developed a nanohybrid material to significantly enhance the catalytic activity of AuNCs by ...

journal_title：Biointerphases

authors： Cho S,Shin HY,Kim MI

更新日期：2017-01-17 00:00:00

abstract：:The mechanical properties and responses of cells to external stimuli (including drugs) are closely connected to important phenomena such as cell spreading, motility, activity, and potentially even differentiation. Here, reversible changes in the viscoelastic properties of surface-attached fibroblasts were induced by t...

journal_title：Biointerphases

authors： Tymchenko N,Nilebäck E,Voinova MV,Gold J,Kasemo B,Svedhem S

更新日期：2012-12-01 00:00:00

abstract：:In plants, algae, and cyanobacteria, photosystem 2 (PS2) catalyzes the light driven oxidation of water. The main products of this reaction are protons and molecular oxygen. In vitro, however, it was demonstrated that reactive oxygen species like hydrogen peroxide are obtained as partially reduced side products. The tr...

journal_title：Biointerphases

authors： Vöpel T,Ning Saw E,Hartmann V,Williams R,Müller F,Schuhmann W,Plumeré N,Nowaczyk M,Ebbinghaus S,Rögner M

更新日期：2015-03-22 00:00:00

abstract：:Antimicrobial peptides (AMPs) are attractive as biomaterial coatings because they have broad spectrum activity against different microbes, with a low likelihood of incurring antimicrobial resistance. Direct action against the bacterial membrane is the most common mechanism of action (MOA) of AMPs, with specific MOAs d...

journal_title：Biointerphases

authors： Alexander TE,Smith IM,Lipsky ZW,Lozeau LD,Camesano TA

更新日期：2020-05-26 00:00:00

abstract：:Herein, the authors report and review polyelectrolyte complex (PEC) nanoparticles (NPs) loaded with zoledronate (ZOL) and simvastatin and their effects on bone cells. PEC NPs are intended for modification of bone substitute materials. For characterization, they can be solution casted on germanium (Ge) substrates servi...

journal_title：Biointerphases

authors： Müller M,Torger B,Wehrum D,Vehlow D,Urban B,Woltmann B,Hempel U

更新日期：2015-03-23 00:00:00

abstract：:Gold nanoparticles (AuNPs) functionalized with a short chain amine-terminated alkanethiol (HS-(CH(2))(2)NH(2) or C2 NH(2)-thiol) are prepared via a direct synthesis method and then ligand-exchanged with a long chain amine-terminated alkanethiol (HS-(CH(2))(11)NH(2) or C11 NH(2)-thiol). Transmission electron microscopy...

journal_title：Biointerphases

authors： Techane SD,Gamble LJ,Castner DG

更新日期：2011-09-01 00:00:00

abstract：:Inspired by the composition of the native extracellular matrix, biomimetic polyelectrolyte multilayers were assembled from polypeptides and the glycosaminoglycan chondroitin sulfate (CS). To investigate whether peptide conformation imposes an effect on the cell biological functions of osteoblasts, the secondary struct...

journal_title：Biointerphases

authors： Grohmann S,Rothe H,Liefeith K

更新日期：2012-12-01 00:00:00

abstract：:Peptide nucleic acids (PNAs) are mimics of oligonucleotides containing a neutral peptidelike backbone and are able to bind complementary DNA targets with high affinity and selectivity. In order to investigate the effect of the ionic strength of the buffer solution, hybridization experiments with PNAs as (catcher) prob...

journal_title：Biointerphases

authors： Park H,Germini A,Sforza S,Corradini R,Marchelli R,Knoll W

更新日期：2007-06-01 00:00:00

abstract：:Fluorescent nanodiamonds (NDs) coated with therapeutics and cell-targeting structures serve as effective tools for drug delivery. However, NDs circulating in blood can eventually interact with the blood-brain barrier, resulting in undesired pathology. Here, we aimed to detect interaction between NDs and adult brain ti...

journal_title：Biointerphases

authors： Šimková V,Freislebenová H,Neuhöferová E,Petráková V,Amini A,Benson V

更新日期：2020-12-03 00:00:00

abstract：:Fast and efficient osseointegration of implants into bone is of crucial importance for their clinical success; a process that can be enhanced by coating the implant surface with hydroxyapatite (HA) using the vacuum plasma spray technology (VPS). However, bacterial infections, especially the biofilm formation on implan...

journal_title：Biointerphases

authors： Guimond-Lischer S,Ren Q,Braissant O,Gruner P,Wampfler B,Maniura-Weber K

更新日期：2016-03-10 00:00:00

abstract：:The peculiar Cuvierian tubules of sea cucumbers function as a defense mechanism. They thwart attacks by creating a sticky network composed of elongated tubules within which the potential predator is entangled in a matter of seconds and thus immobilized. Cuvierian tubules are typical instantaneous adhesive organs in wh...

journal_title：Biointerphases

authors： Demeuldre M,Chinh Ngo T,Hennebert E,Wattiez R,Leclère P,Flammang P

更新日期：2014-06-01 00:00:00

abstract：:The stable nitroxide radical TEMPO [(2,2,6,6-Tetramethylpiperidin-1-yl)oxyl] has a multitude of applications in fields ranging from energy storage to biomedical applications and many more. However, to date, the processes of incorporating nitroxide radicals into thin-film coatings are laborious and not cost-effective, ...

journal_title：Biointerphases

authors： Michl TD,Tran DTT,Böttle K,Kuckling HF,Zhalgasbaikyzy A,Ivanovská B,Cavallaro AA,Araque Toledo MA,Sherman PJ,Al-Bataineh SA,Vasilev K

更新日期：2020-06-26 00:00:00

abstract：:The kinetics of adsorption and desorption of two highly asymmetrical model peptides were studied at methyl- and carboxylic acid-terminated alkylthiolate self-assembled monolayer (SAM) surfaces on gold. The model peptides were leucine-lysine (LK), α-helical (LKα14), and β-strand (LKβ15) peptides that have a well-define...

journal_title：Biointerphases

authors： Apte JS,Gamble LJ,Castner DG,Campbell CT

更新日期：2010-12-01 00:00:00

abstract：:Recent developments in the field of fullerene C60 and its derivatives suggest its suitability in a wide range of applications ranging from photovoltaic instruments, development of solar based cells, cosmetics to enzyme inhibition treatment, and so on. These innovative applications raised possibilities of intentional o...

journal_title：Biointerphases

authors： Biby ET,Prajitha N,Rajeev KS,Mohanan PV

更新日期：2019-03-18 00:00:00

abstract：:Not only bacteria but also fungal pathogens, particularly Candida species, can lead to biofilm infections on biomedical devices. By covalent grafting of the antifungal drug caspofungin, which targets the fungal cell wall, onto solid biomaterials, a surface layer can be created that might be able to provide long-term p...

journal_title：Biointerphases

authors： Griesser SS,Jasieniak M,Coad BR,Griesser HJ

更新日期：2015-12-14 00:00:00

abstract：:Because dental implant abutments are located at transmucosal sites, their surface should inhibit bacterial accumulation to prevent peri-implantitis. The authors examined the effects of human lactoferrin (LF), an antibacterial protein present in saliva, as an antibacterial coating on the titanium surface and evaluated ...

journal_title：Biointerphases

authors： Nagano-Takebe F,Miyakawa H,Nakazawa F,Endo K

更新日期：2014-06-01 00:00:00

abstract：:Unmodified gelatin (uG) is widely used as a coating material in cell culture for improving surface properties. In this study, the authors investigated if gelatin methacrylamide (GM) with a medium degree of methacrylamide modification (GM1.5) and a high degree of methacrylamide modification (GM4) are equally suitable f...

journal_title：Biointerphases

authors： Egger M,Tovar GE,Hoch E,Southan A

更新日期：2016-06-13 00:00:00

abstract：:The limit of detection of advanced immunoassays, biochips and micro/nano biodetection devices is impacted by the non-specific adsorption of target molecules at the sample surface. In this paper, we present a simple and versatile low cost method for generating active surfaces composed of antibodies arrays surrounded by...

journal_title：Biointerphases

authors： Egea AM,Trévisiol E,Vieu C

更新日期：2013-12-01 00:00:00

abstract：:The surface concentration gradient of two extracellular matrix (ECM) macromolecules was developed to study the migratory and morphological responses of astrocytes to molecular cues typically found in the central nervous system injury environment. The gradient, prepared using microcontact printing, was composed of rand...

journal_title：Biointerphases

authors： Hsiao TW,Tresco PA,Hlady V

更新日期：2017-09-11 00:00:00

abstract：:Nanoparticles (NPs) are gaining increasing attention for potential application in medicine; consequently, studying their interaction with cells is of central importance. We found that both ligand arrangement and composition on gold nanoparticles play a crucial role in their cellular internalization. In our previous in...

journal_title：Biointerphases

authors： Carney RP,Carney TM,Mueller M,Stellacci F

更新日期：2012-12-01 00:00:00

abstract：:Microneedle technology is one of the attractive methods in transdermal drug delivery. However, the clinical applications of this method are limited owing to: complexity in the preparation of multiple coating solutions, drug leakage while inserting the microneedles into the skin and the outer walls of the solid microne...

journal_title：Biointerphases

authors： Vinayakumar KB,Hegde GM,Ramachandra SG,Nayak MM,Dinesh NS,Rajanna K

更新日期：2015-06-08 00:00:00

abstract：:The precise use of nanoparticles in technological applications requires control over their surface properties. This implies the ability to quantitatively describe, for example, molecular coatings in terms of their thickness, areal mass, or number of molecules. Here, the authors describe two different approaches to the...

journal_title：Biointerphases

authors： Belsey NA,Shard AG,Minelli C

更新日期：2015-03-27 00:00:00

abstract：:In this systematic review, the authors explored the surface aspects of various titanium (Ti) or Ti alloy medical implants, examining the interface formed between the implant and surrounding nonkeratinized soft tissues (periosteum, muscles, tendons, fat, cicatrix, or dura mater). A comprehensive search undertaken in Ju...

journal_title：Biointerphases

authors： Zigterman BGR,Van den Borre C,Braem A,Mommaerts MY

更新日期：2019-08-16 00:00:00

abstract：:Friction force microscopy was employed for the tribological investigation of human head hair in two different environments: a dry atmosphere and de-ionized water. The fibers were immobilized by embedding them in indium. The effects of bleaching, conditioning, and immersion in methanolic KOH were quantified in terms of...

journal_title：Biointerphases

authors： Nikogeorgos N,Fletcher IW,Boardman C,Doyle P,Ortuoste N,Leggett GJ

更新日期：2010-06-01 00:00:00

abstract：:Many studies have examined the effects of surface topography on the settlement behaviour of marine organisms and this article reviews these investigations with more emphasis on the effects of topography scale. It has been observed that macro topographies (1-100 mm) are generally favoured by marine fouling taxa and are...

journal_title：Biointerphases

authors： Myan FW,Walker J,Paramor O

更新日期：2013-12-01 00:00:00