解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A drug-eluting coating applied onto biomedical devices and implants is an appropriate way to ensure that an inhibitory concentration of antimicrobial drugs is present at the device surface, thus preventing surface colonization and subsequent biofilm formation. In this study, a thin polymer coating was applied to mater...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000511
更新日期:2020-12-18 00:00:00
abstract::Fluorescent nanodiamonds (NDs) coated with therapeutics and cell-targeting structures serve as effective tools for drug delivery. However, NDs circulating in blood can eventually interact with the blood-brain barrier, resulting in undesired pathology. Here, we aimed to detect interaction between NDs and adult brain ti...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000525
更新日期:2020-12-03 00:00:00
abstract::There has been much recent interest in the protein "corona," the nonspecific adsorption of proteins on the surface of nanoparticles used in biological applications. This research investigates an analogous DNA corona. We find that particles (200 nm and 1 μm) incubated with DNA form a DNA corona, with a higher concentra...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000439
更新日期:2020-10-01 00:00:00
abstract::Shewanella oneidensis MR-1 is a dissimilatory metal-reducing bacterium capable of reducing various metal and sulfur compounds and precipitating them in nanoparticulate form. Here, we report the synthesis of molybdenum disulfide nanomaterials at the site of S. oneidensis biofilms grown in the presence of molybdenum tri...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000199
更新日期:2020-07-24 00:00:00
abstract::The stable nitroxide radical TEMPO [(2,2,6,6-Tetramethylpiperidin-1-yl)oxyl] has a multitude of applications in fields ranging from energy storage to biomedical applications and many more. However, to date, the processes of incorporating nitroxide radicals into thin-film coatings are laborious and not cost-effective, ...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000259
更新日期:2020-06-26 00:00:00
abstract::Protein adsorption to biomaterial surfaces is important for the function of such materials with anchorage-dependent cell adhesion requiring the presence of adsorbed proteins. The current study evaluated five solid surfaces with poly(acrylic acid) (PAA) grafted from the surface of a poly(tetrafluoroethylene) membrane w...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000137
更新日期:2020-06-11 00:00:00
abstract::The most common bulk acoustic wave device used in biosensing applications is the quartz crystal microbalance (QCM), in which a resonant pure shear acoustic wave is excited via electrodes on both major faces of a thin AT-cut quartz plate. For biosensing, the QCM is used to detect the capture of a target by a target-cap...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/6.0000144
更新日期:2020-06-02 00:00:00
abstract::Antimicrobial peptides (AMPs) are attractive as biomaterial coatings because they have broad spectrum activity against different microbes, with a low likelihood of incurring antimicrobial resistance. Direct action against the bacterial membrane is the most common mechanism of action (MOA) of AMPs, with specific MOAs d...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5130774
更新日期:2020-05-26 00:00:00
abstract::In this systematic review, the authors explored the surface aspects of various titanium (Ti) or Ti alloy medical implants, examining the interface formed between the implant and surrounding nonkeratinized soft tissues (periosteum, muscles, tendons, fat, cicatrix, or dura mater). A comprehensive search undertaken in Ju...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5113607
更新日期:2019-08-16 00:00:00
abstract::Recent developments in the field of fullerene C60 and its derivatives suggest its suitability in a wide range of applications ranging from photovoltaic instruments, development of solar based cells, cosmetics to enzyme inhibition treatment, and so on. These innovative applications raised possibilities of intentional o...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5084002
更新日期:2019-03-18 00:00:00
abstract::It has been demonstrated that electric fields can minimize surface adhesion of bacteria, but how they affect the near-surface bacterial dynamics has remained largely overlooked. In the present study, the three-dimensional motions of Escherichia coli (E. coli) HCB1 and HCB1414 near a conductive surface under alternatin...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5078543
更新日期:2019-02-20 00:00:00
abstract::Understanding how topographical cues can control cell behavior is a major fundamental question which is of particular interest for implant design. Recent findings show that cell-scale curvature, as well as nanoscale topography, can affect different aspects of cell migration. However, the correlation between specific c...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5042747
更新日期:2018-12-31 00:00:00
abstract::Dentin adhesive systems for composite tooth restorations are composed of hydrophilic/hydrophobic monomers, solvents, and photoinitiators. The adhesives undergo phase separation and concomitant compositional change during their application in the wet oral environment; phase separation compromises the quality of the hyb...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5058072
更新日期:2018-12-17 00:00:00
abstract::Inhalation of combustion-derived ultrafine particles (≤0.1 μm) has been found to be associated with pulmonary and cardiovascular diseases. However, correlation of the physicochemical properties of carbon-based particles such as surface charge and agglomeration state with adverse health effects has not yet been establi...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5043373
更新日期:2018-09-11 00:00:00
abstract::Advances in three-dimensional secondary ion mass spectrometry (SIMS) imaging have enabled visualizing the subcellular distributions of various lipid species within individual cells. However, the difficulty of locating organelles using SIMS limits efforts to study their lipid compositions. Here, the authors have assess...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5019736
更新日期:2018-02-26 00:00:00
abstract::Magnesium alloys are potential biodegradable implants for biomedical applications, and calcium (Ca) is one kind of ideal element being examined for magnesium alloys and biodegradable ceramic coatings owing to its biocompatibility and mechanical suitability. In this study, microarc oxidation (MAO) coatings were prepare...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5003320
更新日期:2018-01-16 00:00:00
abstract::As an antibiotic that prevents and treats infections caused by Gram-positive bacteria such as Staphylococcus aureus, vancomycin incorporated in a biodegradable polymer poly(lactide-co-glycolide) provides opportunities to construct controlled-release drug delivery systems. Developments associated with this promising sy...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5016186
更新日期:2018-01-10 00:00:00
abstract::Mucus is a viscous slime that plays a vital role in protecting and lubricating biological tissues, in particular, soft epithelium interfaces such as in the stomach, intestines, and esophagus. Previous attempts to generate mucus models that mimick or simulate its characteristics have been predominantly focused on the r...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5003708
更新日期:2017-12-05 00:00:00
abstract::Biological membranes and their related molecular mechanisms are essential for all living organisms. Membranes host numerous proteins and are responsible for the exchange of molecules and ions, cell signaling, and cell compartmentation. Indeed, the plasma membrane delimits the intracellular compartment from the extrace...
journal_title:Biointerphases
pub_type: 杂志文章,评审
doi:10.1116/1.4994299
更新日期:2017-09-28 00:00:00
abstract::The surface concentration gradient of two extracellular matrix (ECM) macromolecules was developed to study the migratory and morphological responses of astrocytes to molecular cues typically found in the central nervous system injury environment. The gradient, prepared using microcontact printing, was composed of rand...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.5001675
更新日期:2017-09-11 00:00:00
abstract::Aqueous stability of sputter coated ZnO thin films were studied on two base materials, viz., polycarbonate (PC) and glass. The films showed higher stability on PC compared to glass, when exposed to aqueous buffered solution at pH-7.4, as studied by x-ray diffraction, surface reflectometry, and inductively coupled plas...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4997011
更新日期:2017-08-02 00:00:00
abstract::This contribution reports on grafting of bioactive polymers such as poly(sodium styrene sulfonate) (polyNaSS) onto titanium (Ti) surfaces. This grafting process uses a modified dopamine as an anchor molecule to link polyNaSS to the Ti surface. The grafting process combines reversible addition-fragmentation chain trans...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4985608
更新日期:2017-06-14 00:00:00
abstract::The authors present surface engineering modifications through chemistry of poly(methylmethacrylate) (PMMA) that have dramatic effects on the result of surface-bound fluorescence immunoassays, both for specific and nonspecific signals. The authors deduce the most important effect to be clustering of antibodies on the s...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4984010
更新日期:2017-06-06 00:00:00
abstract::Two-dimensional molybdenum disulfide (MoS2) has attracted intense interest owing to its unique properties and promising biosensor applications. To develop effective biocompatible platforms, it is crucial to understand the interactions between MoS2 and biological molecules such as proteins, but little knowledge exists ...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4984803
更新日期:2017-06-02 00:00:00
abstract::Cationic amphiphilic peptides have been engineered to target both Gram-positive and Gram-negative bacteria while avoiding damage to other cell types. However, the exact mechanism of how these peptides target, bind, and disrupt bacterial cell membranes is not understood. One specific peptide that has been engineered to...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4982710
更新日期:2017-05-05 00:00:00
abstract::Each year, the United States spends about $20 billion to treat people who have been infected with antibiotic resistant bacteria. Even so, the development of new antibiotics has slowed considerably since the mid-20th century. As a result, researchers are looking into developing synthetic compounds and materials with an...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4979918
更新日期:2017-04-20 00:00:00
abstract::Although protein-stabilized gold nanoclusters (AuNCs) have gathered recent attention as biocompatible peroxidase mimics, their practical utility has been critically limited by the low catalytic activity. Here, the authors have developed a nanohybrid material to significantly enhance the catalytic activity of AuNCs by ...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4974198
更新日期:2017-01-17 00:00:00
abstract::Surface plasmon resonance immunosensor for the detection of bacterial cells was first reported in 1998 with high detection limit as much as 107 cfu/ml. Since then, many efforts have been made aiming to lower the detection limit and improve the sensitivity of detection. The aim of this study was to compare the effect o...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4971270
更新日期:2016-12-06 00:00:00
abstract::Understanding and controlling the performance of engineered nanoparticle (NP) systems is greatly assisted by quantitative characterization of their coatings. Useful measurements methods have been described for NPs in liquid environment, but NP aggregation often represents a limiting factor which impairs the accuracy o...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4968882
更新日期:2016-11-30 00:00:00
abstract::Soft x-ray spectromicroscopy techniques have seen great amount of development in the recent years, and with the development of new diffraction limited synchrotron source, many new nanoscale and mesoscale characterization opportunities of applied materials are foreseen. In this perspective, the authors present some exa...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4966654
更新日期:2016-10-28 00:00:00
abstract::Biofunctionalized surfaces for implants are currently receiving much attention in the health care sector. Our aims were (1) to create bioactive Ti-coatings doped with Ca, P, Si, and Ag produced by microarc oxidation (MAO) to improve the surface properties of biomedical implants, (2) to investigate the TiO2 layer stabi...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4960654
更新日期:2016-09-11 00:00:00
abstract::Bacterial colonies that reside on a surface, known as biofilms, are intrinsically impenetrable to traditional antibiotics, ultimately driving research toward an alternative therapeutic approach. Nitric oxide (NO) has gained attention for its biologically beneficial properties, particularly centered around its antibact...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4962266
更新日期:2016-09-07 00:00:00
abstract::Understanding how platelet activation is regulated is important in the context of cardiovascular disorders and their management with antiplatelet therapy. Recent evidence points to different platelet subpopulations performing different functions. In particular, procoagulant and aggregating subpopulations have been rep...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4953866
更新日期:2016-06-22 00:00:00
abstract::Unmodified gelatin (uG) is widely used as a coating material in cell culture for improving surface properties. In this study, the authors investigated if gelatin methacrylamide (GM) with a medium degree of methacrylamide modification (GM1.5) and a high degree of methacrylamide modification (GM4) are equally suitable f...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4949545
更新日期:2016-06-13 00:00:00
abstract::In view of the rare presence of studies concerning platelet function as risk factor in atherosclerotic patients, processes underlying thromboembolic events are reviewed in this paper. The morphology and the structural organization-membrane receptors, the open canalicular and dense tubular systems, the cytoskeleton, mi...
journal_title:Biointerphases
pub_type: 杂志文章,评审
doi:10.1116/1.4953246
更新日期:2016-06-08 00:00:00
abstract::The growing interest in artificial bioorganic interfaces as a platform for applications in emerging areas as personalized medicine, clinical diagnostics, biosensing, biofilms, prevention of biofouling, and other fields of bioengineering is the origin of a need for in detail multitechnique characterizations of such lay...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4948341
更新日期:2016-06-02 00:00:00
abstract::The articular cartilage, once injured, has a limited capacity for intrinsic repair. Preparation of functionally biocartilage substitutes in vitro for cartilage repair is an attractive concept with the recent advances in tissue engineering. In this study, adipose-derived adult stem cells (ADAS) and chondrocytes (Ch) we...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4942754
更新日期:2016-03-25 00:00:00
abstract::Photocorrosion of semiconductors is strongly sensitive to the presence of surface states, and it could be influenced by electrically charged molecules immobilized near the semiconductor/electrolyte interface. The underlying mechanism is related to band bending of the semiconductor structure near the surface and the as...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4941983
更新日期:2016-03-22 00:00:00
abstract::This study presents the morphological and chemical modification of the cell structure of aerosolized Escherichia coli treated with a dielectric barrier discharge (DBD). Exposure to DBD results in severe oxidation of the bacteria, leading to the formation of hydroxyl groups and carbonyl groups and a significant reducti...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4941367
更新日期:2016-03-12 00:00:00
abstract::Fast and efficient osseointegration of implants into bone is of crucial importance for their clinical success; a process that can be enhanced by coating the implant surface with hydroxyapatite (HA) using the vacuum plasma spray technology (VPS). However, bacterial infections, especially the biofilm formation on implan...
journal_title:Biointerphases
pub_type: 杂志文章
doi:10.1116/1.4943225
更新日期:2016-03-10 00:00:00