Abstract：
:Understanding how topographical cues can control cell behavior is a major fundamental question which is of particular interest for implant design. Recent findings show that cell-scale curvature, as well as nanoscale topography, can affect different aspects of cell migration. However, the correlation between specific curvature radii and cell behavior, as well as the combinatorial effect of nanoscale topography and cell-scale curvature, has not yet been investigated. Herein, the authors employ a new femtosecond laser ablation method to generate multiscale topographical patterns directly on titanium surfaces. The process allows us to produce microgrooves of specific curvature imprinted with oriented nanotopographical features called Laser-Induced Periodic Surface Structures (LIPSS). The authors show that curved grooves stimulate the stem cell migration speed in comparison to flat or linear grooves. The fastest velocities are observed on 75 μm curvature radius, whereas cells migrating on 125 μm curvatures exhibit a lower speed similar to the ones migrating on straight lines. Double replicas of these grooves allow us to mask the LIPSS while keeping identical the cell-scale pattern, therefore permitting to uncouple the effect of nanoscale and microscale topographies. The authors found that the presence of nanoscale topographies improves the reading of microgrooves curvature by cells. Altogether, this work shows that the combination of specific curvatures together with nanopatterning can control the velocity of migrating stem cells and promote the use of femtosecond laser ablation in the context of surface implant design.
journal_name
Biointerphasesjournal_title
Biointerphasesauthors
Belaud V,Petithory T,Ponche A,Mauclair C,Donnet C,Pieuchot L,Benayoun S,Anselme Kdoi
10.1116/1.5042747subject
Has Abstractpub_date
2018-12-31 00:00:00pages
06D408issue
6eissn
1934-8630issn
1559-4106journal_volume
13pub_type
杂志文章相关文献
Biointerphases文献大全abstract：:Solid-supported bilayer lipid membranes (SBLMs) containing membrane protein have been generated through a simple lipid dilution technique. SBLM formation from mixtures of native Escherichia coli bacterial inner membrane (IM) vesicles diluted with egg phosphatidylcholine (egg PC) vesicles has been explored with dissipa...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.2896113
更新日期：2008-06-01 00:00:00
abstract：:This study presents the morphological and chemical modification of the cell structure of aerosolized Escherichia coli treated with a dielectric barrier discharge (DBD). Exposure to DBD results in severe oxidation of the bacteria, leading to the formation of hydroxyl groups and carbonyl groups and a significant reducti...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4941367
更新日期：2016-03-12 00:00:00
abstract：:The use of nanoparticles is one of the fastest expanding fields in industrial as well as in medical applications, owing to their remarkable characteristics. Silver nanoparticles (AgNPs) are among the most-commercialized nanoparticles because of their antibacterial effects. Laser postionization secondary neutral mass s...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4937466
更新日期：2015-06-15 00:00:00
abstract：:The application of magnesium alloys as biomaterials is limited by their poor corrosion behavior. Microarc oxidation (MAO) treatment was used to prepare ceramic coatings on ZK60 magnesium alloys in order to overcome the poor corrosion resistance. The process was conducted at different current densities (3.5 and 9.0 A/d...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4889734
更新日期：2014-09-01 00:00:00
abstract：:Bacterial colonies that reside on a surface, known as biofilms, are intrinsically impenetrable to traditional antibiotics, ultimately driving research toward an alternative therapeutic approach. Nitric oxide (NO) has gained attention for its biologically beneficial properties, particularly centered around its antibact...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4962266
更新日期：2016-09-07 00:00:00
abstract：:With the advent of novel fabrication technologies, free-standing poly(l-lactic acid) (PLLA) nanosheets have been shown to have enhanced performance over their micro- or macroscale equivalents as tissue engineering and drug delivery constructs. In the present research, the authors investigated the surface degradation b...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4908206
更新日期：2015-03-20 00:00:00
abstract：:Gold nanoparticles (AuNPs) are good nonviral carriers because of their ease of synthesis and conjugation in biochemistry, and self-assembled monolayers (SAMs) provide a tunable system to change their interfacial properties. Using homogeneously mixed carboxylic acid and amine functional groups, a series of surface pote...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4903934
更新日期：2014-12-01 00:00:00
abstract：:The peculiar Cuvierian tubules of sea cucumbers function as a defense mechanism. They thwart attacks by creating a sticky network composed of elongated tubules within which the potential predator is entangled in a matter of seconds and thus immobilized. Cuvierian tubules are typical instantaneous adhesive organs in wh...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4875731
更新日期：2014-06-01 00:00:00
abstract：:The aim of this research was to assess the influence of mechanical loading on the ability of Zn-free versus Zn-containing amalgams to promote remineralization at the dentin interface. Sound and caries-affected dentin surfaces (CAD) were restored using Zn-free or Zn-containing dental amalgams. Midcoronal dentin surface...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4933243
更新日期：2015-12-19 00:00:00
abstract：:Simulations of water at hydrophilic self-assembled monolayer (SAM) surfaces are especially relevant for biological interfaces. Well-defined, atomically smooth surfaces that can be continuously varied are possible with SAMs. These characteristics enable more accurate measurements than many other surfaces with the added...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.2977751
更新日期：2008-09-01 00:00:00
abstract：:The authors investigate membrane composition-mediated interactions between proteins adsorbed onto a two-component lipid bilayer close to critical demixing using coarse-grained molecular dynamics simulations and a phenomenological Ginzburg-Landau theory. The simulations consist of three-bead lipids and platelike protei...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.2977492
更新日期：2008-06-01 00:00:00
abstract：:Friction force microscopy was employed for the tribological investigation of human head hair in two different environments: a dry atmosphere and de-ionized water. The fibers were immobilized by embedding them in indium. The effects of bleaching, conditioning, and immersion in methanolic KOH were quantified in terms of...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.3432462
更新日期：2010-06-01 00:00:00
abstract：:It has been demonstrated that electric fields can minimize surface adhesion of bacteria, but how they affect the near-surface bacterial dynamics has remained largely overlooked. In the present study, the three-dimensional motions of Escherichia coli (E. coli) HCB1 and HCB1414 near a conductive surface under alternatin...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.5078543
更新日期：2019-02-20 00:00:00
abstract：:Inhalation of combustion-derived ultrafine particles (≤0.1 μm) has been found to be associated with pulmonary and cardiovascular diseases. However, correlation of the physicochemical properties of carbon-based particles such as surface charge and agglomeration state with adverse health effects has not yet been establi...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.5043373
更新日期：2018-09-11 00:00:00
abstract：:The surface concentration gradient of two extracellular matrix (ECM) macromolecules was developed to study the migratory and morphological responses of astrocytes to molecular cues typically found in the central nervous system injury environment. The gradient, prepared using microcontact printing, was composed of rand...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.5001675
更新日期：2017-09-11 00:00:00
abstract：:Unmodified gelatin (uG) is widely used as a coating material in cell culture for improving surface properties. In this study, the authors investigated if gelatin methacrylamide (GM) with a medium degree of methacrylamide modification (GM1.5) and a high degree of methacrylamide modification (GM4) are equally suitable f...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4949545
更新日期：2016-06-13 00:00:00
abstract：:The growing interest in artificial bioorganic interfaces as a platform for applications in emerging areas as personalized medicine, clinical diagnostics, biosensing, biofilms, prevention of biofouling, and other fields of bioengineering is the origin of a need for in detail multitechnique characterizations of such lay...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4948341
更新日期：2016-06-02 00:00:00
abstract：:Aqueous stability of sputter coated ZnO thin films were studied on two base materials, viz., polycarbonate (PC) and glass. The films showed higher stability on PC compared to glass, when exposed to aqueous buffered solution at pH-7.4, as studied by x-ray diffraction, surface reflectometry, and inductively coupled plas...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4997011
更新日期：2017-08-02 00:00:00
abstract：:Biological membranes and their related molecular mechanisms are essential for all living organisms. Membranes host numerous proteins and are responsible for the exchange of molecules and ions, cell signaling, and cell compartmentation. Indeed, the plasma membrane delimits the intracellular compartment from the extrace...
journal_title：Biointerphases
pub_type： 杂志文章,评审
doi：10.1116/1.4994299
更新日期：2017-09-28 00:00:00
abstract：:Hydrotalcite (HT) and other layered double metal hydroxides are of great interest as gene delivery and timed release drug delivery systems and as enteric vehicles for biologically active molecules that are sensitive to gastric fluids. HT is a naturally occurring double metal hydroxide that can be synthesized as a nano...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1186/1559-4106-8-8
更新日期：2013-12-01 00:00:00
abstract：:Gold nanoparticles (AuNPs) functionalized with a short chain amine-terminated alkanethiol (HS-(CH(2))(2)NH(2) or C2 NH(2)-thiol) are prepared via a direct synthesis method and then ligand-exchanged with a long chain amine-terminated alkanethiol (HS-(CH(2))(11)NH(2) or C11 NH(2)-thiol). Transmission electron microscopy...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.3622481
更新日期：2011-09-01 00:00:00
abstract：:Protein adsorption to biomaterial surfaces is important for the function of such materials with anchorage-dependent cell adhesion requiring the presence of adsorbed proteins. The current study evaluated five solid surfaces with poly(acrylic acid) (PAA) grafted from the surface of a poly(tetrafluoroethylene) membrane w...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/6.0000137
更新日期：2020-06-11 00:00:00
abstract：:Neuronal process growth is guided by extrinsic environmental cues such as extracellular matrix (ECM) proteins. Recent reports have described that the growth cone extension is superior across gradients of the ECM protein laminin compared to growth across uniformly distributed laminin. In this work, the authors have pre...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4857295
更新日期：2014-03-01 00:00:00
abstract：:Not only bacteria but also fungal pathogens, particularly Candida species, can lead to biofilm infections on biomedical devices. By covalent grafting of the antifungal drug caspofungin, which targets the fungal cell wall, onto solid biomaterials, a surface layer can be created that might be able to provide long-term p...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4933108
更新日期：2015-12-14 00:00:00
abstract：:Supported phospholipid bilayers are interesting model systems for biologists and present fascinating physical properties. The authors present an extensive experimental study of the dynamic properties of supported bilayers. The structure and the equilibrium properties of single and double supported bilayers were invest...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.2936938
更新日期：2008-06-01 00:00:00
abstract：:The authors present surface engineering modifications through chemistry of poly(methylmethacrylate) (PMMA) that have dramatic effects on the result of surface-bound fluorescence immunoassays, both for specific and nonspecific signals. The authors deduce the most important effect to be clustering of antibodies on the s...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4984010
更新日期：2017-06-06 00:00:00
abstract：:Microneedle technology is one of the attractive methods in transdermal drug delivery. However, the clinical applications of this method are limited owing to: complexity in the preparation of multiple coating solutions, drug leakage while inserting the microneedles into the skin and the outer walls of the solid microne...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4919779
更新日期：2015-06-08 00:00:00
abstract：:The limit of detection of advanced immunoassays, biochips and micro/nano biodetection devices is impacted by the non-specific adsorption of target molecules at the sample surface. In this paper, we present a simple and versatile low cost method for generating active surfaces composed of antibodies arrays surrounded by...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1186/1559-4106-8-37
更新日期：2013-12-01 00:00:00
abstract：:A theoretical framework is developed to analyze molecular bond breaking in dynamic force spectroscopy using atomic force microscopy (AFM). An analytic expression of the observed bond breaking probability as a function of force is obtained in terms of the relevant physical parameters. Three different experimental reali...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.2188519
更新日期：2006-03-01 00:00:00
abstract：:Because dental implant abutments are located at transmucosal sites, their surface should inhibit bacterial accumulation to prevent peri-implantitis. The authors examined the effects of human lactoferrin (LF), an antibacterial protein present in saliva, as an antibacterial coating on the titanium surface and evaluated ...
journal_title：Biointerphases
pub_type： 杂志文章
doi：10.1116/1.4867415
更新日期：2014-06-01 00:00:00
