Effect of ionic strength on PNA-DNA hybridization on surfaces and in solution.

abstract：:A drug-eluting coating applied onto biomedical devices and implants is an appropriate way to ensure that an inhibitory concentration of antimicrobial drugs is present at the device surface, thus preventing surface colonization and subsequent biofilm formation. In this study, a thin polymer coating was applied to mater...

journal_title：Biointerphases

authors： Naderi J,Giles C,Saboohi S,Griesser HJ,Coad BR

更新日期：2020-12-18 00:00:00

abstract：:Not only bacteria but also fungal pathogens, particularly Candida species, can lead to biofilm infections on biomedical devices. By covalent grafting of the antifungal drug caspofungin, which targets the fungal cell wall, onto solid biomaterials, a surface layer can be created that might be able to provide long-term p...

journal_title：Biointerphases

authors： Griesser SS,Jasieniak M,Coad BR,Griesser HJ

更新日期：2015-12-14 00:00:00

abstract：:Gold nanoparticles (AuNPs) are good nonviral carriers because of their ease of synthesis and conjugation in biochemistry, and self-assembled monolayers (SAMs) provide a tunable system to change their interfacial properties. Using homogeneously mixed carboxylic acid and amine functional groups, a series of surface pote...

journal_title：Biointerphases

authors： Chang HY,You YW,Liao HY,Shyue JJ

更新日期：2014-12-01 00:00:00

abstract：:Mucus is a viscous slime that plays a vital role in protecting and lubricating biological tissues, in particular, soft epithelium interfaces such as in the stomach, intestines, and esophagus. Previous attempts to generate mucus models that mimick or simulate its characteristics have been predominantly focused on the r...

journal_title：Biointerphases

authors： Røn T,Patil NJ,Ajalloueian F,Rishikesan S,Zappone B,Chronakis IS,Lee S

更新日期：2017-12-05 00:00:00

abstract：:This contribution reports on grafting of bioactive polymers such as poly(sodium styrene sulfonate) (polyNaSS) onto titanium (Ti) surfaces. This grafting process uses a modified dopamine as an anchor molecule to link polyNaSS to the Ti surface. The grafting process combines reversible addition-fragmentation chain trans...

journal_title：Biointerphases

authors： Chouirfa H,Evans MDM,Castner DG,Bean P,Mercier D,Galtayries A,Falentin-Daudré C,Migonney V

更新日期：2017-06-14 00:00:00

abstract：:In this study, the authors report that sodium citrate can aggregate hexadecyl-trimethyl-ammonium ion(+)-coated gold nanorods (AuNRs), and nucleic acids of different charge and structure properties, i.e., single-stranded DNA (ssDNA), double-stranded DNA (dsDNA), single-stranded peptide nucleic acid (PNA), and PNA-DNA c...

journal_title：Biointerphases

authors： Kanjanawarut R,Su X

更新日期：2010-09-01 00:00:00

abstract：:Nanodiamond (ND) particles are popular platforms for the immobilization of molecular species. In the present research, enzyme Escherichia coli inorganic pyrophosphatase (PPase) was immobilized on detonation ND through covalent or noncovalent bonding and its enzymatic activity was characterized. Factors affecting adsor...

journal_title：Biointerphases

authors： Rodina EV,Valueva AV,Yakovlev RY,Vorobyeva NN,Kulakova II,Lisichkin GV,Leonidov NB

更新日期：2015-12-21 00:00:00

abstract：:The application of magnesium alloys as biomaterials is limited by their poor corrosion behavior. Microarc oxidation (MAO) treatment was used to prepare ceramic coatings on ZK60 magnesium alloys in order to overcome the poor corrosion resistance. The process was conducted at different current densities (3.5 and 9.0 A/d...

journal_title：Biointerphases

authors： You Q,Yu H,Wang H,Pan Y,Chen C

更新日期：2014-09-01 00:00:00

abstract：:Titanium dental implants are commonly used for the replacement of lost teeth, but they present a considerable number of failures due to the infection on surrounding tissues. The aim of this paper is the development of a polyethylene glycol-like (PEG-like) coating on the titanium surface by plasma polymerization to obt...

journal_title：Biointerphases

authors： Buxadera-Palomero J,Canal C,Torrent-Camarero S,Garrido B,Javier Gil F,Rodríguez D

更新日期：2015-06-12 00:00:00

abstract：:Commonly used implants for therapeutic approaches of non-systemically impaired bone do not sufficiently support the healing process of osteoporotic bone. Since strontium (II) has been proven as an effective anti-osteoporotic drug new types of strontium enriched calcium phosphate bone cements were developed. As osteopo...

journal_title：Biointerphases

authors： Kokesch-Himmelreich J,Schumacher M,Rohnke M,Gelinsky M,Janek J

更新日期：2013-12-01 00:00:00

abstract：:Force spectroscopy has been used to measure the adhesion of Saos-2 cells to a glass surface at different phases of the cell cycle. The cells were synchronized in three phases of the cell cycle: G(1), S, and G(2)M. Cells in these phases were compared with unsynchronized and native mitotic cells. Individual cells were a...

journal_title：Biointerphases

authors： Weder G,Vörös J,Giazzon M,Matthey N,Heinzelmann H,Liley M

更新日期：2009-06-01 00:00:00

abstract：:Cationic amphiphilic peptides have been engineered to target both Gram-positive and Gram-negative bacteria while avoiding damage to other cell types. However, the exact mechanism of how these peptides target, bind, and disrupt bacterial cell membranes is not understood. One specific peptide that has been engineered to...

journal_title：Biointerphases

authors： Golbek TW,Franz J,Elliott Fowler J,Schilke KF,Weidner T,Baio JE

更新日期：2017-05-05 00:00:00

abstract：:Photocorrosion of semiconductors is strongly sensitive to the presence of surface states, and it could be influenced by electrically charged molecules immobilized near the semiconductor/electrolyte interface. The underlying mechanism is related to band bending of the semiconductor structure near the surface and the as...

journal_title：Biointerphases

authors： Aziziyan MR,Hassen WM,Morris D,Frost EH,Dubowski JJ

更新日期：2016-03-22 00:00:00

abstract：:Solid-supported bilayer lipid membranes (SBLMs) containing membrane protein have been generated through a simple lipid dilution technique. SBLM formation from mixtures of native Escherichia coli bacterial inner membrane (IM) vesicles diluted with egg phosphatidylcholine (egg PC) vesicles has been explored with dissipa...

journal_title：Biointerphases

authors： Dodd CE,Johnson BR,Jeuken LJ,Bugg TD,Bushby RJ,Evans SD

更新日期：2008-06-01 00:00:00

abstract：:As an antibiotic that prevents and treats infections caused by Gram-positive bacteria such as Staphylococcus aureus, vancomycin incorporated in a biodegradable polymer poly(lactide-co-glycolide) provides opportunities to construct controlled-release drug delivery systems. Developments associated with this promising sy...

journal_title：Biointerphases

authors： Du L,Yang X,Li W,Li H,Feng S,Zeng R,Yu B,Xiao L,Liu Y,Tu M,Nie HY

更新日期：2018-01-10 00:00:00

abstract：:The growing interest in artificial bioorganic interfaces as a platform for applications in emerging areas as personalized medicine, clinical diagnostics, biosensing, biofilms, prevention of biofouling, and other fields of bioengineering is the origin of a need for in detail multitechnique characterizations of such lay...

journal_title：Biointerphases

authors： Dietrich PM,Nietzold C,Weise M,Unger WE,Alnabulsi S,Moulder J

更新日期：2016-06-02 00:00:00

abstract：:The authors report a facile method for the selective immobilization of biomolecules onto a gold surface that was preactivated by a polymeric adlayer. The polymeric adlayer was designed to perform triple functions: high resistance to nonspecific protein adsorption, efficient surface anchoring, and subsequent covalent a...

journal_title：Biointerphases

authors： Lee BS,Park S,Lee KB,Jon S,Choi IS

更新日期：2007-12-01 00:00:00

abstract：:There has been much recent interest in the protein "corona," the nonspecific adsorption of proteins on the surface of nanoparticles used in biological applications. This research investigates an analogous DNA corona. We find that particles (200 nm and 1 μm) incubated with DNA form a DNA corona, with a higher concentra...

journal_title：Biointerphases

authors： Griffith DM,Jayaram DT,Spencer DM,Pisetsky DS,Payne CK

更新日期：2020-10-01 00:00:00

abstract：:The kinetics of adsorption and desorption of two highly asymmetrical model peptides were studied at methyl- and carboxylic acid-terminated alkylthiolate self-assembled monolayer (SAM) surfaces on gold. The model peptides were leucine-lysine (LK), α-helical (LKα14), and β-strand (LKβ15) peptides that have a well-define...

journal_title：Biointerphases

authors： Apte JS,Gamble LJ,Castner DG,Campbell CT

更新日期：2010-12-01 00:00:00

abstract：:To image inflammation sites, we developed a novel nanoparticle, hydroxylamine-containing nanoparticle (HANP), which emits an intense electron spin resonance (ESR)-signal triggered by enzymatic oxidation reaction and pH-sensitive self-disintegration. The nanoparticle was prepared from an amphiphilic block copolymer, po...

journal_title：Biointerphases

authors： Yoshitomi T,Nagasaki Y

更新日期：2012-12-01 00:00:00

abstract：:Microneedle technology is one of the attractive methods in transdermal drug delivery. However, the clinical applications of this method are limited owing to: complexity in the preparation of multiple coating solutions, drug leakage while inserting the microneedles into the skin and the outer walls of the solid microne...

journal_title：Biointerphases

authors： Vinayakumar KB,Hegde GM,Ramachandra SG,Nayak MM,Dinesh NS,Rajanna K

更新日期：2015-06-08 00:00:00

abstract：:The modeling, fabrication, cell loading, and mechanical and in vitro biological testing of biomimetic, interlockable, laser-made, concentric 3D scaffolds are presented. The scaffolds are made by multiphoton polymerization of an organic-inorganic zirconium silicate. Their mechanical properties are theoretically modeled...

journal_title：Biointerphases

authors： Danilevicius P,Rezende RA,Pereira FD,Selimis A,Kasyanov V,Noritomi PY,da Silva JV,Chatzinikolaidou M,Farsari M,Mironov V

更新日期：2015-06-23 00:00:00

abstract：:Understanding how topographical cues can control cell behavior is a major fundamental question which is of particular interest for implant design. Recent findings show that cell-scale curvature, as well as nanoscale topography, can affect different aspects of cell migration. However, the correlation between specific c...

journal_title：Biointerphases

authors： Belaud V,Petithory T,Ponche A,Mauclair C,Donnet C,Pieuchot L,Benayoun S,Anselme K

更新日期：2018-12-31 00:00:00

abstract：:In view of the rare presence of studies concerning platelet function as risk factor in atherosclerotic patients, processes underlying thromboembolic events are reviewed in this paper. The morphology and the structural organization-membrane receptors, the open canalicular and dense tubular systems, the cytoskeleton, mi...

journal_title：Biointerphases

authors： Reinthaler M,Braune S,Lendlein A,Landmesser U,Jung F

更新日期：2016-06-08 00:00:00

abstract：:Hydrotalcite (HT) and other layered double metal hydroxides are of great interest as gene delivery and timed release drug delivery systems and as enteric vehicles for biologically active molecules that are sensitive to gastric fluids. HT is a naturally occurring double metal hydroxide that can be synthesized as a nano...

journal_title：Biointerphases

authors： Sanderson BA,Sowersby DS,Crosby S,Goss M,Lewis LK,Beall GW

更新日期：2013-12-01 00:00:00

abstract：:Two-dimensional molybdenum disulfide (MoS2) has attracted intense interest owing to its unique properties and promising biosensor applications. To develop effective biocompatible platforms, it is crucial to understand the interactions between MoS2 and biological molecules such as proteins, but little knowledge exists ...

journal_title：Biointerphases

authors： Fan H,Zhao D,Li Y,Zhou J

更新日期：2017-06-02 00:00:00

abstract：:The mechanical properties and responses of cells to external stimuli (including drugs) are closely connected to important phenomena such as cell spreading, motility, activity, and potentially even differentiation. Here, reversible changes in the viscoelastic properties of surface-attached fibroblasts were induced by t...

journal_title：Biointerphases

authors： Tymchenko N,Nilebäck E,Voinova MV,Gold J,Kasemo B,Svedhem S

更新日期：2012-12-01 00:00:00

abstract：:Magnesium alloys are potential biodegradable implants for biomedical applications, and calcium (Ca) is one kind of ideal element being examined for magnesium alloys and biodegradable ceramic coatings owing to its biocompatibility and mechanical suitability. In this study, microarc oxidation (MAO) coatings were prepare...

journal_title：Biointerphases

authors： Pan Y,Chen C,Feng R,Cui H,Gong B,Zheng T,Ji Y

更新日期：2018-01-16 00:00:00

abstract：:In this systematic review, the authors explored the surface aspects of various titanium (Ti) or Ti alloy medical implants, examining the interface formed between the implant and surrounding nonkeratinized soft tissues (periosteum, muscles, tendons, fat, cicatrix, or dura mater). A comprehensive search undertaken in Ju...

journal_title：Biointerphases

authors： Zigterman BGR,Van den Borre C,Braem A,Mommaerts MY

更新日期：2019-08-16 00:00:00

abstract：:The articular cartilage, once injured, has a limited capacity for intrinsic repair. Preparation of functionally biocartilage substitutes in vitro for cartilage repair is an attractive concept with the recent advances in tissue engineering. In this study, adipose-derived adult stem cells (ADAS) and chondrocytes (Ch) we...

journal_title：Biointerphases

authors： Yeh HY,Hsieh FY,Hsu SH

更新日期：2016-03-25 00:00:00