Development of cup shaped microneedle array for transdermal drug delivery.

abstract：:Shewanella oneidensis MR-1 is a dissimilatory metal-reducing bacterium capable of reducing various metal and sulfur compounds and precipitating them in nanoparticulate form. Here, we report the synthesis of molybdenum disulfide nanomaterials at the site of S. oneidensis biofilms grown in the presence of molybdenum tri...

journal_title：Biointerphases

authors： Rees JD,Gorby YA,Sawyer SM

更新日期：2020-07-24 00:00:00

abstract：:Photocorrosion of semiconductors is strongly sensitive to the presence of surface states, and it could be influenced by electrically charged molecules immobilized near the semiconductor/electrolyte interface. The underlying mechanism is related to band bending of the semiconductor structure near the surface and the as...

journal_title：Biointerphases

authors： Aziziyan MR,Hassen WM,Morris D,Frost EH,Dubowski JJ

更新日期：2016-03-22 00:00:00

abstract：:Cationic amphiphilic peptides have been engineered to target both Gram-positive and Gram-negative bacteria while avoiding damage to other cell types. However, the exact mechanism of how these peptides target, bind, and disrupt bacterial cell membranes is not understood. One specific peptide that has been engineered to...

journal_title：Biointerphases

authors： Golbek TW,Franz J,Elliott Fowler J,Schilke KF,Weidner T,Baio JE

更新日期：2017-05-05 00:00:00

abstract：:Photolithographic techniques have been used to fabricate polymer brush micro- and nanostructures. On exposure to UV light with a wavelength of 244 nm, halogens were selectively removed from films of chloromethylphenyltrichlorosilane and 3-(2-bromoisobutyramido)propyl-triethoxysilane on silicon dioxide. Patterning was ...

journal_title：Biointerphases

authors： Ahmad SA,Leggett GJ,Hucknall A,Chilkoti A

更新日期：2011-03-01 00:00:00

abstract：:The authors report on the characterization of the charge formation at supported bilayer lipid membranes (sBLMs) prepared from the zwitterionic lipid 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine on planar silicon dioxide substrates. The charging of the sBLMs was studied in KCl solutions of different ionic strengths be...

journal_title：Biointerphases

authors： Zimmermann R,Küttner D,Renner L,Kaufmann M,Zitzmann J,Müller M,Werner C

更新日期：2009-01-01 00:00:00

abstract：:Peptide nucleic acids (PNAs) are mimics of oligonucleotides containing a neutral peptidelike backbone and are able to bind complementary DNA targets with high affinity and selectivity. In order to investigate the effect of the ionic strength of the buffer solution, hybridization experiments with PNAs as (catcher) prob...

journal_title：Biointerphases

authors： Park H,Germini A,Sforza S,Corradini R,Marchelli R,Knoll W

更新日期：2007-06-01 00:00:00

abstract：:Diamond has outstanding bulk properties such as super hardness, chemical inertness, biocompatibility, luminescence, to name just a few. In the nanoworld, in order to exploit these outstanding bulk properties, the surfaces of nanodiamond (ND) particles must be accordingly engineered for specific applications. Modificat...

journal_title：Biointerphases

authors： Shenderova OA,McGuire GE

更新日期：2015-09-05 00:00:00

abstract：:In this study, the authors report that sodium citrate can aggregate hexadecyl-trimethyl-ammonium ion(+)-coated gold nanorods (AuNRs), and nucleic acids of different charge and structure properties, i.e., single-stranded DNA (ssDNA), double-stranded DNA (dsDNA), single-stranded peptide nucleic acid (PNA), and PNA-DNA c...

journal_title：Biointerphases

authors： Kanjanawarut R,Su X

更新日期：2010-09-01 00:00:00

abstract：:Neuronal process growth is guided by extrinsic environmental cues such as extracellular matrix (ECM) proteins. Recent reports have described that the growth cone extension is superior across gradients of the ECM protein laminin compared to growth across uniformly distributed laminin. In this work, the authors have pre...

journal_title：Biointerphases

authors： Zander NE,Beebe TP Jr

更新日期：2014-03-01 00:00:00

abstract：:Dodecin from Halobacterium salinarum is a dodecameric, hollow-spherical protein, which unspecifically adopts flavin molecules. Reduction of flavin dodecin holocomplexes induces dissociation into apododecin and free flavin. Unspecific binding and dissociation upon reduction were used as key properties to construct an e...

journal_title：Biointerphases

authors： Grininger M,Nöll G,Trawöger S,Sinner EK,Oesterhelt D

更新日期：2008-09-01 00:00:00

abstract：:Biofunctionalized surfaces for implants are currently receiving much attention in the health care sector. Our aims were (1) to create bioactive Ti-coatings doped with Ca, P, Si, and Ag produced by microarc oxidation (MAO) to improve the surface properties of biomedical implants, (2) to investigate the TiO2 layer stabi...

journal_title：Biointerphases

authors： Marques Ida S,Alfaro MF,Saito MT,da Cruz NC,Takoudis C,Landers R,Mesquita MF,Nociti Junior FH,Mathew MT,Sukotjo C,Barão VA

更新日期：2016-09-11 00:00:00

abstract：:A drug-eluting coating applied onto biomedical devices and implants is an appropriate way to ensure that an inhibitory concentration of antimicrobial drugs is present at the device surface, thus preventing surface colonization and subsequent biofilm formation. In this study, a thin polymer coating was applied to mater...

journal_title：Biointerphases

authors： Naderi J,Giles C,Saboohi S,Griesser HJ,Coad BR

更新日期：2020-12-18 00:00:00

abstract：:Magnesium alloys are potential biodegradable implants for biomedical applications, and calcium (Ca) is one kind of ideal element being examined for magnesium alloys and biodegradable ceramic coatings owing to its biocompatibility and mechanical suitability. In this study, microarc oxidation (MAO) coatings were prepare...

journal_title：Biointerphases

authors： Pan Y,Chen C,Feng R,Cui H,Gong B,Zheng T,Ji Y

更新日期：2018-01-16 00:00:00

abstract：:Friction force microscopy was employed for the tribological investigation of human head hair in two different environments: a dry atmosphere and de-ionized water. The fibers were immobilized by embedding them in indium. The effects of bleaching, conditioning, and immersion in methanolic KOH were quantified in terms of...

journal_title：Biointerphases

authors： Nikogeorgos N,Fletcher IW,Boardman C,Doyle P,Ortuoste N,Leggett GJ

更新日期：2010-06-01 00:00:00

abstract：:Titanium dental implants are commonly used for the replacement of lost teeth, but they present a considerable number of failures due to the infection on surrounding tissues. The aim of this paper is the development of a polyethylene glycol-like (PEG-like) coating on the titanium surface by plasma polymerization to obt...

journal_title：Biointerphases

authors： Buxadera-Palomero J,Canal C,Torrent-Camarero S,Garrido B,Javier Gil F,Rodríguez D

更新日期：2015-06-12 00:00:00

abstract：:Reliable, direct "sample-to-answer" capture of nucleic acid targets from complex media would greatly improve existing capabilities of DNA microarrays and biosensors. This goal has proven elusive for many current nucleic acid detection technologies attempting to produce assay results directly from complex real-world sa...

journal_title：Biointerphases

authors： Lee CY,Gamble LJ,Grainger DW,Castner DG

更新日期：2006-06-01 00:00:00

abstract：:Inspired by the composition of the native extracellular matrix, biomimetic polyelectrolyte multilayers were assembled from polypeptides and the glycosaminoglycan chondroitin sulfate (CS). To investigate whether peptide conformation imposes an effect on the cell biological functions of osteoblasts, the secondary struct...

journal_title：Biointerphases

authors： Grohmann S,Rothe H,Liefeith K

更新日期：2012-12-01 00:00:00

abstract：:Understanding how platelet activation is regulated is important in the context of cardiovascular disorders and their management with antiplatelet therapy. Recent evidence points to different platelet subpopulations performing different functions. In particular, procoagulant and aggregating subpopulations have been rep...

journal_title：Biointerphases

authors： Donati A,Gupta S,Reviakine I

更新日期：2016-06-22 00:00:00

abstract：:This contribution reports on grafting of bioactive polymers such as poly(sodium styrene sulfonate) (polyNaSS) onto titanium (Ti) surfaces. This grafting process uses a modified dopamine as an anchor molecule to link polyNaSS to the Ti surface. The grafting process combines reversible addition-fragmentation chain trans...

journal_title：Biointerphases

authors： Chouirfa H,Evans MDM,Castner DG,Bean P,Mercier D,Galtayries A,Falentin-Daudré C,Migonney V

更新日期：2017-06-14 00:00:00

abstract：:The mechanical properties and responses of cells to external stimuli (including drugs) are closely connected to important phenomena such as cell spreading, motility, activity, and potentially even differentiation. Here, reversible changes in the viscoelastic properties of surface-attached fibroblasts were induced by t...

journal_title：Biointerphases

authors： Tymchenko N,Nilebäck E,Voinova MV,Gold J,Kasemo B,Svedhem S

更新日期：2012-12-01 00:00:00

abstract：:Because dental implant abutments are located at transmucosal sites, their surface should inhibit bacterial accumulation to prevent peri-implantitis. The authors examined the effects of human lactoferrin (LF), an antibacterial protein present in saliva, as an antibacterial coating on the titanium surface and evaluated ...

journal_title：Biointerphases

authors： Nagano-Takebe F,Miyakawa H,Nakazawa F,Endo K

更新日期：2014-06-01 00:00:00

abstract：:Fluorescent nanodiamonds (NDs) coated with therapeutics and cell-targeting structures serve as effective tools for drug delivery. However, NDs circulating in blood can eventually interact with the blood-brain barrier, resulting in undesired pathology. Here, we aimed to detect interaction between NDs and adult brain ti...

journal_title：Biointerphases

authors： Šimková V,Freislebenová H,Neuhöferová E,Petráková V,Amini A,Benson V

更新日期：2020-12-03 00:00:00

abstract：:The authors present surface engineering modifications through chemistry of poly(methylmethacrylate) (PMMA) that have dramatic effects on the result of surface-bound fluorescence immunoassays, both for specific and nonspecific signals. The authors deduce the most important effect to be clustering of antibodies on the s...

journal_title：Biointerphases

authors： Akers PW,Hoai Le NC,Nelson ARJ,McKenna M,O'Mahony C,McGillivray DJ,Gubala V,Williams DE

更新日期：2017-06-06 00:00:00

abstract：:Inhalation of combustion-derived ultrafine particles (≤0.1 μm) has been found to be associated with pulmonary and cardiovascular diseases. However, correlation of the physicochemical properties of carbon-based particles such as surface charge and agglomeration state with adverse health effects has not yet been establi...

journal_title：Biointerphases

authors： Durantie E,Barosova H,Drasler B,Rodriguez-Lorenzo L,Urban DA,Vanhecke D,Septiadi D,Hirschi-Ackermann L,Petri-Fink A,Rothen-Rutishauser B

更新日期：2018-09-11 00:00:00

abstract：:Aqueous stability of sputter coated ZnO thin films were studied on two base materials, viz., polycarbonate (PC) and glass. The films showed higher stability on PC compared to glass, when exposed to aqueous buffered solution at pH-7.4, as studied by x-ray diffraction, surface reflectometry, and inductively coupled plas...

journal_title：Biointerphases

authors： Vallam Thodi F,Thendiyammal A,Mukundakumar B,Subbiah K,T Sainathan C

更新日期：2017-08-02 00:00:00

abstract：:Supported phospholipid bilayers are interesting model systems for biologists and present fascinating physical properties. The authors present an extensive experimental study of the dynamic properties of supported bilayers. The structure and the equilibrium properties of single and double supported bilayers were invest...

journal_title：Biointerphases

authors： Charitat T,Lecuyer S,Fragneto G

更新日期：2008-06-01 00:00:00

abstract：:The modeling, fabrication, cell loading, and mechanical and in vitro biological testing of biomimetic, interlockable, laser-made, concentric 3D scaffolds are presented. The scaffolds are made by multiphoton polymerization of an organic-inorganic zirconium silicate. Their mechanical properties are theoretically modeled...

journal_title：Biointerphases

authors： Danilevicius P,Rezende RA,Pereira FD,Selimis A,Kasyanov V,Noritomi PY,da Silva JV,Chatzinikolaidou M,Farsari M,Mironov V

更新日期：2015-06-23 00:00:00

abstract：:In plants, algae, and cyanobacteria, photosystem 2 (PS2) catalyzes the light driven oxidation of water. The main products of this reaction are protons and molecular oxygen. In vitro, however, it was demonstrated that reactive oxygen species like hydrogen peroxide are obtained as partially reduced side products. The tr...

journal_title：Biointerphases

authors： Vöpel T,Ning Saw E,Hartmann V,Williams R,Müller F,Schuhmann W,Plumeré N,Nowaczyk M,Ebbinghaus S,Rögner M

更新日期：2015-03-22 00:00:00

abstract：:Nanoparticles (NPs) are gaining increasing attention for potential application in medicine; consequently, studying their interaction with cells is of central importance. We found that both ligand arrangement and composition on gold nanoparticles play a crucial role in their cellular internalization. In our previous in...

journal_title：Biointerphases

authors： Carney RP,Carney TM,Mueller M,Stellacci F

更新日期：2012-12-01 00:00:00

abstract：:A theoretical framework is developed to analyze molecular bond breaking in dynamic force spectroscopy using atomic force microscopy (AFM). An analytic expression of the observed bond breaking probability as a function of force is obtained in terms of the relevant physical parameters. Three different experimental reali...

journal_title：Biointerphases

authors： Hanke F,Kreuzer HJ

更新日期：2006-03-01 00:00:00