The responses of pollen to applied electrical fields.

abstract：:In vertebrates, nodal-related genes are crucial for specifying mesendodermal cell fates. Six nodal-related genes have been identified in Xenopus, but only one, nodal, has been identified in the mouse. The Xenopus nodal-related gene 3 (Xnr3), however, lacks the mesoderm-inducing activity of the other five nodal-related...

journal_title：Developmental biology

authors： Haramoto Y,Tanegashima K,Onuma Y,Takahashi S,Sekizaki H,Asashima M

更新日期：2004-01-01 00:00:00

abstract：:The inactivation of the prolactin receptor gene by homologous recombination has made it possible to investigate the role of prolactin signaling in mammary gland development without resort to ablative surgery of the endocrine glands. In knockout mice lacking the prolactin receptor, mammary development is normal up to p...

journal_title：Developmental biology

authors： Brisken C,Kaur S,Chavarria TE,Binart N,Sutherland RL,Weinberg RA,Kelly PA,Ormandy CJ

更新日期：1999-06-01 00:00:00

abstract：:Notch activation inhibits neuronal differentiation during development of the nervous system; however, the dynamic role of Notch signaling in individual cell lineages remains poorly understood. We have characterized 3.4 kb 5'-regulatory sequence of a Notch target gene, her4, and used it to drive fluorescent gene expres...

journal_title：Developmental biology

authors： Yeo SY,Kim M,Kim HS,Huh TL,Chitnis AB

更新日期：2007-01-15 00:00:00

abstract：:Congenital bony syngnathia, a rare but severe human birth defect, is characterized by bony fusion of the mandible to the maxilla. However, the genetic mechanisms underlying this birth defect are poorly understood, largely due to limitation of available animal models. Here we present evidence that transgenic expression...

journal_title：Developmental biology

authors： He F,Hu X,Xiong W,Li L,Lin L,Shen B,Yang L,Gu S,Zhang Y,Chen Y

更新日期：2014-07-15 00:00:00

abstract：:Electroporation-based assays were used to test whether the myogenic regulatory factor (MRF) of Ciona intestinalis (CiMRF) interferes with endogenous developmental programs, and to evaluate the importance of its unusual N-terminus for muscle development. We found that CiMRF suppresses both notochord and endoderm develo...

journal_title：Developmental biology

authors： Ratcliffe LE,Asiedu EK,Pickett CJ,Warburton MA,Izzi SA,Meedel TH

更新日期：2019-04-15 00:00:00

abstract：:The relationship between cellular position and growth control has been studied in cultures of dissociated fragments of mouse limb bud cells. Using cells derived from various positions along the anterior-posterior axis of the limb bud we have developed culture conditions that optimize growth of positionally isolated ce...

journal_title：Developmental biology

authors： Shi C,Muneoka K

更新日期：1992-05-01 00:00:00

abstract：:I report on the synthesis of fibronectin in the developing chick Müllerian duct mesenchymal cells. Before the differentiation of female chick Müllerian duct, the amount of fibronectin in the cells of the right duct is 44% lower than in the left duct. While after differentiation, the amount of fibronectin in the right ...

journal_title：Developmental biology

authors： Teng CS

更新日期：1990-07-01 00:00:00

abstract：:In many organisms early embryogenesis is characterised by a period refractory to transcription. In Caenorhabditis elegans, the one-cell embryo is transcriptionally inactive, but at around eight-cell stage transcription is activated in the somatic lineage. This model suggests that histone tail modifications associated ...

journal_title：Developmental biology

authors： Wang S,Fisher K,Poulin GB

更新日期：2011-07-15 00:00:00

abstract：:Tubes with distinct shapes and sizes are critical for the proper function of many tubular organs. Here we describe a unique phenotype caused by the loss of a novel, evolutionarily-conserved, Drosophila Smad-like protein, Expansion. In expansion mutants, unicellular and intracellular tracheal branches develop bubble-li...

journal_title：Developmental biology

authors： Iordanou E,Chandran RR,Yang Y,Essak M,Blackstone N,Jiang L

更新日期：2014-09-01 00:00:00

abstract：:In the vertebrate head, crucial parts of the sense organs and sensory ganglia develop from special regions, the cranial placodes. Despite their cellular and functional diversity, they arise from a common field of multipotent progenitors and acquire distinct identity later under the influence of local signalling. Here ...

journal_title：Developmental biology

authors： Grocott T,Tambalo M,Streit A

更新日期：2012-10-01 00:00:00

abstract：:Tube formation is a widespread process during organogenesis. Specific cellular behaviors participate in the invagination of epithelial monolayers that form tubes. However, little is known about the evolutionary mechanisms of cell assembly into tubes during development. In Caenorhabditis elegans, the detailed step-to-s...

journal_title：Developmental biology

authors： Kolotuev I,Podbilewicz B

更新日期：2004-02-15 00:00:00

abstract：:RNA localization is tightly coordinated with RNA stability and translation control. Bicaudal-D (Bic-D), Egalitarian (Egl), microtubules and their motors are part of a Drosophila transport machinery that localizes mRNAs to specific cellular regions during oogenesis and embryogenesis. We identified the Poly(A)-binding p...

journal_title：Developmental biology

authors： Vazquez-Pianzola P,Urlaub H,Suter B

更新日期：2011-09-15 00:00:00

abstract：:Cadherin-mediated cell-cell interactions are thought to be critical in controlling cell sorting during embryogenesis. Here, we report that chimeric embryos generated with N-cadherin-deficient (N-cadherin(-/-)) embryonic stem cells develop further than embryos completely lacking N-cadherin only when the myocardium cons...

journal_title：Developmental biology

authors： Kostetskii I,Moore R,Kemler R,Radice GL

更新日期：2001-06-01 00:00:00

abstract：:Stem cells are essential for the regeneration and homeostasis of many organs, such as tooth, hair, skin, and intestine. Although human tooth regeneration is limited, a number of animals have evolved continuously growing teeth that provide models of stem cell-based organ renewal. A well-studied model is the mouse incis...

journal_title：Developmental biology

authors： Li CY,Cha W,Luder HU,Charles RP,McMahon M,Mitsiadis TA,Klein OD

更新日期：2012-06-15 00:00:00

abstract：:Normal growth and morphogenesis of the cranial vault reflect a balance between cell proliferation in the sutures and osteogenesis at the margins of the cranial bones. In the clinical condition craniosynostosis, the sutures fuse prematurely as a result of precocious osteogenic differentiation and craniofacial malformat...

journal_title：Developmental biology

authors： Moore R,Ferretti P,Copp A,Thorogood P

更新日期：2002-03-01 00:00:00

abstract：:Using gene-specific probes derived from four mouse gamma-crystallin cDNAs, we have examined the regulation of different members of the mouse gamma-crystallin gene family during lens development. Our analysis revealed that, while the different gamma-crystallin genes appear to be coordinately activated during embryogene...

journal_title：Developmental biology

authors： Murer-Orlando M,Paterson RC,Lok S,Tsui LC,Breitman ML

更新日期：1987-01-01 00:00:00

abstract：:Establishment and maintenance of functional stem cells is critical for organ development and tissue homeostasis. Little is known about the mechanisms underlying stem establishment during organogenesis. Drosophila testes are among the most thoroughly characterized systems for studying stem cell behavior, with germline ...

journal_title：Developmental biology

authors： Sinden D,Badgett M,Fry J,Jones T,Palmen R,Sheng X,Simmons A,Matunis E,Wawersik M

更新日期：2012-12-01 00:00:00

abstract：:Murine ovarian folliculogenesis commences after birth involving oocyte growth, somatic cell differentiation and structural remodeling of follicle stromal boundaries. The extracellular metalloproteinase ADAMTS-1 has activity against proteoglycans and collagen and is produced by the granulosa cells of ovarian follicles....

journal_title：Developmental biology

authors： Brown HM,Dunning KR,Robker RL,Pritchard M,Russell DL

更新日期：2006-12-15 00:00:00

abstract：:Mouse oocytes at metaphase I of meiotic maturation were treated with puromycin, which caused the condensed chromosomes to become decondensed to form an interphase nucleus. The chromosomes returned to a metaphase state 6.3 hr after the oocytes were transferred to puromycin-free medium [H. J. Clarke and Y. Masui (1983) ...

journal_title：Developmental biology

authors： Clarke HJ,Masui Y

更新日期：1985-03-01 00:00:00

abstract：:The HNK-1 antibody recognizes a carbohydrate moiety that is shared by a family of cell adhesion molecules and is also present on the surface of migrating neural crest cells. Here, the effects of the HNK-1 antibody on neural crest cells were examined in vitro and in vivo. When the HNK-1 antibody was added to neural tub...

journal_title：Developmental biology

authors： Bronner-Fraser M

更新日期：1987-10-01 00:00:00

abstract：:Congenital diseases caused by abnormal development of the cranial neural crest usually present craniofacial malformations and heart defects while the precise mechanism is not fully understood. Here, we show that the zebrafish eif3ba mutant caused by pseudo-typed retrovirus insertion exhibited a similar phenotype due t...

journal_title：Developmental biology

authors： Xia Z,Tong X,Liang F,Zhang Y,Kuok C,Zhang Y,Liu X,Zhu Z,Lin S,Zhang B

更新日期：2013-09-01 00:00:00

abstract：:To examine the role of postsynaptic activity in regulating the rate of neuromuscular synapse elimination, contractile activity of neonatal rabbit soleus muscles was decreased by chronic superfusion of alpha-bungarotoxin (alpha-BGT) over their surfaces. Superfusion was begun at 6 days postnatal and continued for a vari...

journal_title：Developmental biology

authors： Callaway EM,Van Essen DC

更新日期：1989-02-01 00:00:00

abstract：:The transition from maternal to zygotic gene expression in the mouse occurs in the 2-cell embryo. Previous studies in which DNA was injected into 2-cell embryos revealed that transcription promoters and origins of DNA replication are strongly repressed in cleavage stage embryos unless linked to an embryo-responsive en...

journal_title：Developmental biology

authors： Henery CC,Miranda M,Wiekowski M,Wilmut I,DePamphilis ML

更新日期：1995-06-01 00:00:00

abstract：:The origin of resident (noninflammatory) macrophages in vertebrate tissues is still poorly understood. In the zebrafish embryo, we recently described a specific lineage of early macrophages that differentiate in the yolk sac before the onset of blood circulation. We now show that these early macrophages spread in the ...

journal_title：Developmental biology

authors： Herbomel P,Thisse B,Thisse C

更新日期：2001-10-15 00:00:00

abstract：:Kidney development is a complex, little understood process based on inductive interactions and intricate epithelial and mesenchymal morphogenesis. Here, we report the use of subtractive hybridization to clone cDNAs expressed in early nephrogenesis. cDNA made from E14.5 mouse kidney was hybridized with adult mouse live...

journal_title：Developmental biology

authors： McConnell JE,Armstrong JF,Hodges PE,Bard JB

更新日期：1995-05-01 00:00:00

abstract：:Mutations at the Drosophila melanogaster locus female sterile (1) homeotic (fs(1)h) result in segmental abnormalities including missing organs and homeotic transformations in the progeny of mutant mothers. Homeotic transformations are enhanced when the zygotes carry one of several third chromosome mutations, specifica...

journal_title：Developmental biology

authors： Digan ME,Haynes SR,Mozer BA,Dawid IB,Forquignon F,Gans M

更新日期：1986-03-01 00:00:00

abstract：:Developing cardiac myocytes divide a limited number of times before they stop and terminally differentiate, but the mechanism that stops their division is unknown. To help study the stopping mechanism, we defined conditions under which embryonic rat cardiac myocytes cultured in serum-free medium proliferate and exit t...

journal_title：Developmental biology

authors： Burton PB,Raff MC,Kerr P,Yacoub MH,Barton PJ

更新日期：1999-12-15 00:00:00

abstract：:The source of neurite outgrowth in explant cultures of normal adult Apteronotus spinal cord was examined. Explants which contained the central region of spinal cord, including ependyma, showed neurite outgrowth in culture. Explants which did not contain ependyma showed no neurite outgrowth. It is concluded that the ep...

journal_title：Developmental biology

authors： Anderson MJ,Waxman SG,Fong HL

更新日期：1987-02-01 00:00:00

abstract：:Bone development is dependent on the functionality of three essential cell types: chondrocytes, osteoclasts and osteoblasts. If any of these cell types is dysfunctional, a developmental bone phenotype can result. The bone disease osteopetrosis is caused by osteoclast dysfunction or impaired osteoclastogenesis, leading...

journal_title：Developmental biology

authors： Neutzsky-Wulff AV,Sims NA,Supanchart C,Kornak U,Felsenberg D,Poulton IJ,Martin TJ,Karsdal MA,Henriksen K

更新日期：2010-08-15 00:00:00

abstract：:The Mesp bHLH genes play a conserved role during segmental patterning of the mesoderm in the vertebrate embryo by specifying segmental boundaries and anteroposterior (A-P) segmental polarity. Here we use a xenotransgenic approach to compare the transcriptional enhancers that drive expression of the Mesp genes within s...

journal_title：Developmental biology

authors： Moreno TA,Jappelli R,Izpisúa Belmonte JC,Kintner C

更新日期：2008-03-15 00:00:00