Angiogenesis in endometrial carcinoma: Therapies and biomarkers, current options, and future perspectives.

abstract：OBJECTIVE:The value of surgical staging of apparent early stage epithelial ovarian carcinoma (EOC) is unclear. The aim of this study was to evaluate the importance of surgical staging on the stage of disease and treatment plan. MATERIAL AND METHODS:All patients with apparent stage I EOC undergoing staging from 01/01/2...

journal_title：Gynecologic oncology

authors： Hengeveld EM,Zusterzeel PLM,Lajer H,Høgdall CK,Rosendahl M

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain. METHODS:1043 histological confirmed ICC cases diagnosed from 1940 to 2007 ...

journal_title：Gynecologic oncology

authors： Alemany L,Pérez C,Tous S,Llombart-Bosch A,Lloveras B,Lerma E,Guarch R,Andújar M,Pelayo A,Alejo M,Ordi J,Klaustermeier J,Velasco J,Guimerà N,Clavero O,Castellsagué X,Quint W,Muñoz N,Bosch FX,de Sanjosé S,Spanish st

更新日期：2012-03-01 00:00:00

abstract：:The association between spontaneous abortion and gestational trophoblastic disease (GTD) has been investigated in a study based on 93 women with 2 consecutive (repeated) spontaneous abortions and 82 control subjects who delivered normal babies. Nine molar pregnancies were observed among 7 of the 93 cases of repeated a...

journal_title：Gynecologic oncology

authors： Acaia B,Parazzini F,La Vecchia C,Ricciardiello O,Fedele L,Battista Candiani G

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:To assess the ability of the Age-Adjusted Charlson Comorbidity Index (ACCI) to predict perioperative complications and survival in patients undergoing primary debulking for advanced epithelial ovarian cancer (EOC). METHODS:Data were analyzed for all patients with stage IIIB-IV EOC who underwent primary cytor...

journal_title：Gynecologic oncology

authors： Suidan RS,Leitao MM Jr,Zivanovic O,Gardner GJ,Long Roche KC,Sonoda Y,Levine DA,Jewell EL,Brown CL,Abu-Rustum NR,Charlson ME,Chi DS

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Hemangiomas are very rare tumors of the ovary. Here, we report a case of a mixed capillary and cavernous ovarian hemangioma and endometrial carcinoma presenting with postmenopausal bleeding, male pattern receding frontal hairline, and high serum androgen and estradiol levels. CASE:A 70-year-old White female...

journal_title：Gynecologic oncology

authors： Gücer F,Ozyilmaz F,Balkanli-Kaplan P,Mülayim N,Aydin O

更新日期：2004-09-01 00:00:00

abstract：:Malignant ovarian germ cell tumors (OGCT) and sex cord-stromal tumors (OSCST), each of which account for less than 5% of all ovarian malignancies, are much less common than epithelial ovarian cancer. In young patients suspected of having an OGCT, laparotomy is initially indicated for both diagnosis and treatment. For ...

journal_title：Gynecologic oncology

authors： Gershenson DM

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:To determine whether chemotherapy-induced neutropenia (C-iN) is associated with improved survival in a population of primary advanced ovarian cancer and peritoneal carcinoma patients treated with a carboplatin plus paclitaxel chemotherapy backbone. METHODS:A post-hoc exploratory analysis of Gynecologic Oncol...

journal_title：Gynecologic oncology

authors： Tewari KS,Java JJ,Gatcliffe TA,Bookman MA,Monk BJ

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To evaluate safety, tolerability, and antitumor activity of pembrolizumab monotherapy in patients with programmed death ligand 1 (PD-L1)-expressing advanced ovarian cancer enrolled in the multicohort, phase Ib KEYNOTE-028 trial. METHODS:Key inclusion criteria were age ≥18 years; advanced ovarian epithelial, ...

journal_title：Gynecologic oncology

authors： Varga A,Piha-Paul S,Ott PA,Mehnert JM,Berton-Rigaud D,Morosky A,Yang P,Ruman J,Matei D

更新日期：2019-02-01 00:00:00

abstract：:Sclerosing stromal cell tumors of the ovary are an uncommon neoplasm that usually does not produce hormonal imbalances. Most patients showing a hormonal effect from this lesion have had menstrual cycle disturbances. Infertility and endometrial hyperplasia have also been described. One other reported case had masculini...

journal_title：Gynecologic oncology

authors： Cashell AW,Cohen ML

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To present the clinical application of the multispectral imaging colposcopic system (MIS colposcopy). METHODS:MIS colposcopy was performed on 123 enrolled women. After a 3% acetic acid application, sequential images were captured, analyzed, and stored automatically. Directed biopsies were taken from distinct...

journal_title：Gynecologic oncology

authors： Orfanoudaki IM,Themelis GC,Sifakis SK,Fragouli DH,Panayiotides JG,Vazgiouraki EM,Koumantakis EE

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:A LEEP-Cone may not be necessary for all patients with traditional cone indications. This study defines populations where a single pass technique with the LEEP is appropriate. METHODS:We retrospectively reviewed patients undergoing LEEP-Cone procedures performed at the University of Oklahoma Health Science C...

journal_title：Gynecologic oncology

authors： Tillmanns TD,Falkner CA,Engle DB,Wan JY,Mannel RS,Walker JL,Johnson GA,McMeekin DS,Zuna R,Gold MA

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Ovarian cancer arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy is rare. CASE:We herein report the case of a 67-year-old woman with a history of breast cancer, taking tamoxifen citrate 20 mg/day for 4 years, who underwent an operation for left ovarian tumor. The postopera...

journal_title：Gynecologic oncology

authors： Okugawa K,Hirakawa T,Ogawa S,Kaku T,Nakano H

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:We wanted to identify genes up-regulated in ovarian tumors that might serve as early markers for ovarian cancer. One promising focus is the family of genes that encode secreted proteases, which play essential roles in tumor invasion and metastasis. Kallikrein 10 (KLK10) is a member of the kallikrein family of...

journal_title：Gynecologic oncology

authors： Shvartsman HS,Lu KH,Lee J,Lillie J,Deavers MT,Clifford S,Wolf JK,Mills GB,Bast RC Jr,Gershenson DM,Schmandt R

更新日期：2003-07-01 00:00:00

abstract：:One hundred fifty-five patients with cervical cancer not amenable to radical surgery underwent selective, paraaortic lymphadenectomy and exploratory laparotomy prior to the initiation of radiotherapy. Fifty-one patients underwent transperitoneal lymphadenectomy; the remainder had the procedure performed using the extr...

journal_title：Gynecologic oncology

authors： Podczaski ES,Palombo C,Manetta A,Andrews C,Larson J,DeGeest K,Mortel R

更新日期：1989-04-01 00:00:00

abstract：:Ovarian germ cell tumors (GCTs) are rare in adults, but are more common in adolescents and young adults. Contemporary management of ovarian GCTs is evolving as collaboration among pediatric, medical, and gynecologic oncologists increases, and studies increasingly incorporate female adult patients. Despite an improved ...

journal_title：Gynecologic oncology

authors： Veneris JT,Mahajan P,Frazier AL

更新日期：2020-08-01 00:00:00

abstract：:Adenocarcinoma of the cervix represents an increasing percentage of cervical cancers as well as a controversial clinical problem. One hundred seventy-two cases of adenocarcinoma were treated at The University of Michigan Medical Center from 1970 to 1984, representing 16.8% of cervical cancers. Of this group 84 patient...

journal_title：Gynecologic oncology

authors： Hopkins MP,Sutton P,Roberts JA

更新日期：1987-05-01 00:00:00

abstract：:A case of spontaneous internal jugular vein thrombosis associated with distant malignancy is presented. This unusual manifestation of a hypercoagulable state was associated with a low-grade epithelioid leiomyosarcoma of the omentum. It was discovered on a gynecologic oncology service in a patient explored for a pelvic...

journal_title：Gynecologic oncology

authors： Langlieb AM,Dunton CJ,Carlson JA Jr

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Uterine leiomyomas rarely cause pseudo-Meigs' syndrome with elevated serum CA 125 levels. CASE:A 39-year-old patient with a large uterine leiomyoma is described. The associated massive ascites, pleural fluid, and increased CA 125 level all seemed to be related to the uterine tumor. Hydropic degenerating lei...

journal_title：Gynecologic oncology

authors： Amant F,Gabriel C,Timmerman D,Vergote I

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classical glycolytic protein. A higher level of GAPDH mRNA was found in lung, pancreas, and prostate cancers, but in cervical carcinoma there have not been any reports about the level of GAPDH gene expression. So, we tried to investigate the GAPDH gene exp...

journal_title：Gynecologic oncology

authors： Kim JW,Kim SJ,Han SM,Paik SY,Hur SY,Kim YW,Lee JM,Namkoong SE

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:The ovarian yolk sac tumor (OYST) is a very rare malignancy arising in young women. Our objective was to determine whether an early decline in serum alpha-fetoprotein (AFP) during chemotherapy has a prognostic impact. METHODS:This retrospective study is based on prospectively recorded OYST cases at Gustave ...

journal_title：Gynecologic oncology

authors： de la Motte Rouge T,Pautier P,Genestie C,Rey A,Gouy S,Leary A,Haie-Meder C,Kerbrat P,Culine S,Fizazi K,Lhommé C

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Lymph node status in endometrial cancer is a major prognostic factor. Sentinel lymph node (SLN) biopsy using radiocolloid and blue dye labeling has emerged as an alternative to systematic lymphadenectomy. This technique requires a preoperative lymphoscintigraphy. The aim of this study was to evaluate the limi...

journal_title：Gynecologic oncology

authors： Ballester M,Rouzier R,Coutant C,Kerrou K,Daraï E

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Recent studies of ovarian cancer have suggested a role for inflammation in carcinogenesis. Data from a population-based case-control study in Hawaii were examined to assess the relation between polymorphisms in cytokines involved with the inflammatory response, specifically members of the interleukin (IL) fam...

journal_title：Gynecologic oncology

authors： Bushley AW,Ferrell R,McDuffie K,Terada KY,Carney ME,Thompson PJ,Wilkens LR,Tung KH,Ness RB,Goodman MT

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE(S):To determine whether antibiotic treatment (ABX) during platinum chemotherapy (PC) for epithelial ovarian cancer (EOC) impacts progression-free survival (PFS) and overall survival (OS). STUDY DESIGN:Retrospective single institution cohort study in women with newly diagnosed stage III/IV EOC (n = 424) who u...

journal_title：Gynecologic oncology

authors： Chambers LM,Kuznicki M,Yao M,Chichura A,Gruner M,Reizes O,Debernardo R,Rose PG,Michener C,Vargas R

更新日期：2020-12-01 00:00:00

abstract：:Open biopsy of the left scalene lymph nodes has been utilized to identify distant spread of cervical carcinoma in selected groups of patients who do not have other clinical evidence of disseminated disease. Twenty-one patients with primary cervical carcinoma and histologically proven para-aortic lymph node metastases ...

journal_title：Gynecologic oncology

authors： Burke TW,Heller PB,Hoskins WJ,Weiser EB,Nash JD,Park RC

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Neuroendocrine carcinomas (NECs) of the cervix comprise only 2% of all cervical cancers. Prospective data is limited and treatment guidelines rely on retrospective reviews and literature from lung NEC. The objective of this study was to report our experience in the management of this rare disease. METHODS:T...

journal_title：Gynecologic oncology

authors： McCann GA,Boutsicaris CE,Preston MM,Backes FJ,Eisenhauer EL,Fowler JM,Cohn DE,Copeland LJ,Salani R,O'Malley DM

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the efficacy and hematologic toxicity of salvage chemotherapy in patients with recurrent ovarian cancer following high-dose chemotherapy and peripheral blood stem cell transplantation (PBSCT). METHODS:A retrospective analysis of 19 Massachusetts General Hospital c...

journal_title：Gynecologic oncology

authors： Cook S,Penson R,Duska L,Nikrui N,Goodman A,Fuller A,Seiden M

更新日期：2000-04-01 00:00:00

abstract：:Placement of a radiation implant in patients with cervical cancer may be difficult because of distortion of the canal by tumor or fibrosis from previous radiation. The objective of this study was to determine whether ultrasound may be useful in recognizing or preventing complications associated with placement of an in...

journal_title：Gynecologic oncology

authors： Rotmensch J,Waggoner SE,Quiet C

更新日期：1994-08-01 00:00:00

abstract：PURPOSE:A phase II trial was conducted to evaluate the anti-tumor activity and adverse effects of capecitabine in women with measurable platinum-sensitive ovarian cancer or platinum-sensitive primary peritoneal cancer and to explore the ability of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), and th...

journal_title：Gynecologic oncology

authors： Garcia AA,Blessing JA,Lenz HJ,Darcy KM,Mannel RS,Miller DS,Husseinzadeh N,Gynecologic Oncology Group.

更新日期：2005-03-01 00:00:00

abstract：:Twenty-nine patients with recurrent advanced stage ovarian cancer were treated with 5-fluorouracil (5-FU) and leucovorin by intravenous bolus on 5 consecutive days, repeated every 3 weeks. Twenty-one of these patients had experienced disease progression while receiving a cisplatin- or carboplatin-based regimen. There ...

journal_title：Gynecologic oncology

authors： Reed E,Jacob J,Ozols RF,Young RC,Allegra C

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVES:The aim of this prospective study was to evaluate the impact of integrated PET-CT on treatment management in ovarian carcinoma recurrence suspicion because of increased CA-125. METHODS:Twenty-nine patients (mean age=61 years), initially treated for ovarian carcinoma (FIGO stage I n=2, stage II n=3, stage II...

journal_title：Gynecologic oncology

authors： Soussan M,Wartski M,Cherel P,Fourme E,Goupil A,Le Stanc E,Callet N,Alexandre J,Pecking AP,Alberini JL

更新日期：2008-01-01 00:00:00