Prognostic features and treatment of endocervical adenocarcinoma of the cervix.

abstract：BACKGROUND:Ovarian cancer arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy is rare. CASE:We herein report the case of a 67-year-old woman with a history of breast cancer, taking tamoxifen citrate 20 mg/day for 4 years, who underwent an operation for left ovarian tumor. The postopera...

journal_title：Gynecologic oncology

authors： Okugawa K,Hirakawa T,Ogawa S,Kaku T,Nakano H

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:The aims of this study were (1) to examine whether HPV DNA is persistently detected in the cervix after therapeutic conization for CIN 3 and (2) to explore whether a patient with persistence of HPV infection is at risk of developing recurrent disease. METHODS:Of 74 patients referred with CIN 3, 58 who were t...

journal_title：Gynecologic oncology

authors： Nagai Y,Maehama T,Asato T,Kanazawa K

更新日期：2000-11-01 00:00:00

abstract：:Between 1972 and 1977, 141 patients with benign gynecologic disease and 149 patients with carcinoma of the cervix were evaluated with peritoneal fluid cytology at time of celiotomy. There was no positive cytology (malignant cells) in the benign disease group. The overall incidence of positive peritoneal cytology in th...

journal_title：Gynecologic oncology

authors： Abu-Ghazaleh S,Johnston W,Creasman WT

更新日期：1984-02-01 00:00:00

abstract：:Ovarian carcinomas of similar histology have variable responses to radiation therapy. It has been suggested that inherent cellular resistance to radiation may in part underlie radiotherapy failure. To determine in vitro radiobiological parameters of papillary serous adenocarcinoma of the ovary, we investigated the cel...

journal_title：Gynecologic oncology

authors： Rotmensch J,Schwartz JL,Atcher RW,Grdina DJ,Toohill M,Weichselbaum RW

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVE:This study aims to estimate the activity of docetaxel 60mg/m(2) IV over 1h followed by trabectedin 1.1mg/m(2) over 3h with filgrastim, pegfilgrastim, or sargramostim every 3weeks (one cycle). METHODS:Patients with recurrent and measurable disease, acceptable organ function, PS≤2, and ≤3 prior regimens were e...

journal_title：Gynecologic oncology

authors： Monk BJ,Sill MW,Hanjani P,Edwards R,Rotmensch J,De Geest K,Bonebrake AJ,Walker JL

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Nicaragua has some of the highest rates of cervical cancer in Latin America and the world. In 2003, the Nicaraguan Ministry of Health, the Central American Institute of Health and the Maria Luisa Ortiz Clinic combined efforts to create an effective remote rural service network, with centralized quality-contr...

journal_title：Gynecologic oncology

authors： Howe SL,Vargas DE,Granada D,Smith JK

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:The correlation between p53 tumor suppressor gene mutations and the presence of high-risk human papillomavirus (HPV) DNA with the in vitro radiosensitivity of gynecological malignancies was studied in 26 cell lines derived from gynecological cancers of 23 patients. METHODS:Comparison of the intrinsic radiose...

journal_title：Gynecologic oncology

authors： Rantanen V,Grénman S,Kurvinen K,Hietanen S,Raitanen M,Syrjänen S

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:To identify an indicator that can predict tumor cell spread beyond the uterine corpus. METHODS:We studied clinicopathology and immunohistochemistry of 12 cases of PSTT. Two cases of epithelioid trophoblastic tumor (ETT) were included as reference cases. For immunohistochemistry, antibodies against Ki-67, p5...

journal_title：Gynecologic oncology

authors： Nagai Y,Kamoi S,Matsuoka T,Hata A,Jobo T,Ogasawara T,Aoki Y,Ohira S,Okamoto T,Nakamoto T,Kanda K,Matsui H

更新日期：2007-09-01 00:00:00

abstract：:By serendipity we have had the opportunity to evaluate cis-platin-based chemotherapy in ovarian tumors of low malignant potential (LMP). Optimal (less than 1 cm residual disease) FIGO stage III ovarian carcinomas were randomly assigned to treatment with cisplatin plus cyclophosphamide with or without doxorubicin on a ...

journal_title：Gynecologic oncology

authors： Sutton GP,Bundy BN,Omura GA,Yordan EL,Beecham JB,Bonfiglio T

更新日期：1991-06-01 00:00:00

abstract：:The first case report of a 58-year-old woman with two different primary carcinoid tumors is presented. The bronchial carcinoid exhibited a mosaic pattern, whereas the ovarian tumor showed both insular and trabecular patterns. No teratomatous component was observed in the ovary. Both tumors presented an argyrophil reac...

journal_title：Gynecologic oncology

authors： Sorbe B,Valentin K,Wilander E

更新日期：1986-11-01 00:00:00

abstract：:Normal and neoplastic endometrial tissues were examined immunohistochemically for chromogranin which was shown to be a specific marker for neuroendocrine cells. All 20 normal endometriums and 20 endometrial carcinomas without argyrophilia were chromogranin negative. Endometrial carcinomas with argyrophilia tested were...

journal_title：Gynecologic oncology

authors： Ueda G,Nishino T,Saito J,Abe Y,Shimizu H,Tanizawa O

更新日期：1987-06-01 00:00:00

abstract：:To develop a mapping strategy for improved detection of p53 allelic loss associated with ovarian carcinoma, we utilized multiple intragenic polymorphisms and single-strand conformation polymorphism (SSCP) analysis. p53 allelotype distributions were defined for 80 ovarian cancer patients from germ-line DNA. All polymor...

journal_title：Gynecologic oncology

authors： Skilling JS,Powills K,Lager DJ,Anderson B,Sorosky J,Buller RE

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:The present study aimed to identify differentially expressed proteins employing a high resolution mass spectrometry (MS)-based proteomic analysis of endometrial cancer cells harvested using laser microdissection. METHODS:A differential MS-based proteomic analysis was conducted from discrete epithelial cell p...

journal_title：Gynecologic oncology

authors： Maxwell GL,Hood BL,Day R,Chandran U,Kirchner D,Kolli VS,Bateman NW,Allard J,Miller C,Sun M,Flint MS,Zahn C,Oliver J,Banerjee S,Litzi T,Parwani A,Sandburg G,Rose S,Becich MJ,Berchuck A,Kohn E,Risinger JI,Conrad

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:The effect on progesterone and estrogen receptor expression in glands and stroma after two different treatment regimens of endometrial hyperplasia was determined. METHODS:Pre- and post-treatment paraffin-embedded endometrial hyperplasia specimens from women treated with levonorgestrel (LNG) intrauterine dev...

journal_title：Gynecologic oncology

authors： Vereide AB,Kaino T,Sager G,Arnes M,Ørbo A

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The ovarian yolk sac tumor (OYST) is a very rare malignancy arising in young women. Our objective was to determine whether an early decline in serum alpha-fetoprotein (AFP) during chemotherapy has a prognostic impact. METHODS:This retrospective study is based on prospectively recorded OYST cases at Gustave ...

journal_title：Gynecologic oncology

authors： de la Motte Rouge T,Pautier P,Genestie C,Rey A,Gouy S,Leary A,Haie-Meder C,Kerbrat P,Culine S,Fizazi K,Lhommé C

更新日期：2016-09-01 00:00:00

abstract：:Thirty-two patients with Stage III or IV epithelial ovarian cancer and residual tumor volumes in excess of 2 cm in diameter after initial debulking were treated with platinum and cyclophosphamide chemotherapy. Twenty-seven patients (84%) received at least six courses of chemotherapy. Six patients developed grade 3 or ...

journal_title：Gynecologic oncology

authors： Gallion HH,van Nagell JR,Donaldson ES,Hanson MB,Kryscio RJ

更新日期：1987-06-01 00:00:00

abstract：:Twenty cases of gestational trophoblastic disease in women aged 50 or more are reported. The lesions were 7 hydatidiform mole (35%), 8 invasive mole (40%), and 5 choriocarcinoma (25%). The most common presenting symptom was abnormal vaginal bleeding. Three choriocarcinoma patients were postmenopausal and all of them h...

journal_title：Gynecologic oncology

authors： Tsukamoto N,Iwasaka T,Kashimura Y,Uchino H,Kashimura M,Matsuyama T

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to evaluate the efficacy of postoperative concurrent chemoradiotherapy (CCRT) and to investigate the recurrence and survival rates after adjuvant CCRT in high-risk early cervical cancer (stages IA2, IB, IIA) patients who were treated by radical hysterectomy and pelvic lymphadenectomy...

journal_title：Gynecologic oncology

authors： Ryu HS,Chun M,Chang KH,Chang HJ,Lee JP

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To evaluate c-erbB2 gene amplification in a series of primary uterine serous carcinoma (USC) cell lines. To assess the efficacy of AZD8055, a novel dual mTORC1/2 inhibitor against primary HER2/neu amplified vs HER2/neu not amplified USC cell lines. METHODS:Twenty-two primary USC cell lines were evaluated for...

journal_title：Gynecologic oncology

authors： English DP,Roque DM,Carrara L,Lopez S,Bellone S,Cocco E,Bortolomai I,Schwartz PE,Rutherford T,Santin AD

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the 5-year survival probability (SP) of patients treated for ovarian clear cell adenocarcinoma (OCCA) at a single tertiary institution and to compare it to the 5-year SP of patients with other histologic subtypes of epithelial ovarian cancer. METHODS:Sixty-four patients ...

journal_title：Gynecologic oncology

authors： Kennedy AW,Markman M,Biscotti CV,Emery JD,Rybicki LA

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:To determine the overall survival and relative effect of multiple prognostic variables in cohorts of patients with advanced-stage ovarian cancer treated with platinum-based neoadjuvant chemotherapy in lieu of primary cytoreductive surgery. METHODS:Twenty-two cohorts of patients with Stage III and IV ovarian ...

journal_title：Gynecologic oncology

authors： Bristow RE,Chi DS

更新日期：2006-12-01 00:00:00

abstract：:The carcinoembryonic antigen (CEA) in the cyst fluid of ovarian mucinous and serous tumors was investigated. The molecular weight and antigenicity of the CEA from both ovarian tumors were very similar to those of colon cancer CEA as determined by SDS electrophoresis and double immunodiffusion on agar plates. In the cy...

journal_title：Gynecologic oncology

authors： Tohya T,Iwamasa T,Maeyama M

更新日期：1986-03-01 00:00:00

abstract：:Clinical research in gynecologic oncology has seen a proliferation of studies that investigate the effectiveness of treatments using existing data sources such as cancer registries, electronic health records, and insurance claims. These observational studies are often feasible when randomized trial may not be, and may...

journal_title：Gynecologic oncology

authors： Moss HA,Melamed A,Wright JD

更新日期：2019-03-01 00:00:00

abstract：:In patients with small central recurrences following radiation therapy for cervical cancer the surgeon may have to make a judgment as to when radical hysterectomy is preferable to exenteration. During the years 1968-1984 there were 21 radical hysterectomies performed at Memorial Sloan-Kettering Cancer Center for recur...

journal_title：Gynecologic oncology

authors： Rubin SC,Hoskins WJ,Lewis JL Jr

更新日期：1987-07-01 00:00:00

abstract：:The optimal treatment of early-stage ovarian borderline tumors is controversial. Only a few randomized trials evaluating adjuvant treatment for this disease have been published. Between 1970 and 1988 four consecutive randomized trials, including patients with ovarian borderline tumors, were conducted at the Norwegian ...

journal_title：Gynecologic oncology

authors： Tropé C,Kaern J,Vergote IB,Kristensen G,Abeler V

更新日期：1993-11-01 00:00:00

abstract：:We examined the efficacy of CA125 and urinary gonadotropin fragment (UGF) measurements for differentiating benign from malignant pelvic masses. CA125, at a cutoff of greater than or equal to 35 U/ml, detected 82% (n = 71) of ovarian malignancies, but also falsely detected 14% of (n = 332) patients with benign pelvic m...

journal_title：Gynecologic oncology

authors： Cole LA,Nam JH,Chambers JT,Schwartz PE

更新日期：1990-03-01 00:00:00

abstract：:We have previously reported an overall response rate of 41% and a median survival duration of 14 months in a series of 49 patients with metastatic or recurrent endometrial carcinoma treated by a combination of etoposide, 5-fluorouracil, and cisplatin. In order to increase response rate and survival duration, doxorubic...

journal_title：Gynecologic oncology

authors： Pierga JY,Diéras V,Beuzeboc P,Dorval T,Palangié T,Jouve M,Scholl SM,Garcia-Giralt E,Pouillart P

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:To assess the utility of tumor diameter (TD) for predicting lymphatic dissemination (LD) and determining need for lymphadenectomy following diagnosis of endometrioid endometrial cancer. METHODS:Patients diagnosed with stage I-III endometrioid endometrial cancer during 2003-2013 who underwent pelvic or para-...

journal_title：Gynecologic oncology

authors： Cox Bauer CM,Greer DM,Kram JJF,Kamelle SA

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Topotecan (1.5 mg/m(2)) administered daily for 5 consecutive days of a 21-day cycle is an established chemotherapeutic regimen in recurrent ovarian cancer. However, noncumulative myelosuppression has limited its use by many clinicians. We sought to determine whether a lower dose of topotecan could provide com...

journal_title：Gynecologic oncology

authors： Rodriguez M,Rose PG

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy between acupuncture and ondansetron in the prevention of delayed chemotherapy induced nausea and vomiting (CINV). METHODS:70 patients were randomized to receive either 1) acupuncture at P6 point before chemotherapy infusion or 2) ondansetron 8 mg intravenously 30 min before chemothera...

journal_title：Gynecologic oncology

authors： Rithirangsriroj K,Manchana T,Akkayagorn L

更新日期：2015-01-01 00:00:00