p53 allelotypes and enhanced detection of allelic loss in ovarian cancer: lack of correlation with familial and clinical factors.

abstract：BACKGROUND:A case of primary neuroblastoma arising from the broad ligament with excellent response to neoadjuvant bleomycin, etoposide, and cisplatin (BEP) is reported. CASE:A 48-year-old woman, G0, who presented with acute renal failure, an enlarged pelvic mass, and abdominal pain was diagnosed with adult neuroblasto...

journal_title：Gynecologic oncology

authors： Milam MR,Gabel SF,Milam RA,Liu J,Ramirez PT

更新日期：2007-11-01 00:00:00

abstract：:Iatrogenic immune suppression following renal transplantation is frequently associated with certain neoplasms, including vulvar carcinoma. We describe a patient with a vulvar carcinoma less than 1 mm depth of invasion and less than 3 mm superficial spread 12 years after renal transplantation. A simple vulvectomy was p...

journal_title：Gynecologic oncology

authors： Volgger B,Marth C,Zeimet A,Müller-Holzner E,Ruth N,Dapunt O

更新日期：1997-04-01 00:00:00

abstract：:After standard management of stage III-IV ovarian cancer patients by surgical reduction of tumor mass and subsequent cisplatin-based combination chemotherapy, eradication of residual intraabdominal disease remains a major clinical problem. In an effort to increase response to therapy without adding marrow toxicity, af...

journal_title：Gynecologic oncology

authors： Campora E,Bruzzone M,Chiara S,Alama A,Iskra L,Carnino F,Parodi S,Foglia G,Ragni N,Rosso R

更新日期：1990-04-01 00:00:00

abstract：:Favorable responses to hexamethylmelamine (HMM) have been documented in untreated as well as in alkylating agent-resistant ovarian epithelial adenocarcinoma (OvCa). Platinum-based combination therapy for OvCa has been used since 1976. Eighteen patients with OvCa were treated with HMM as salvage therapy between Februar...

journal_title：Gynecologic oncology

authors： Stehman FB,Ehrlich CE,Callangan MF

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Ovarian cancer is the deadliest gynecologic malignancy, yet the effects on survival of modifiable pre-diagnosis lifestyle factors, such as obesity and physical activity, remain largely unexplored. Our objective was to evaluate the effect of pre-diagnosis BMI and physical activity on ovarian cancer mortality ...

journal_title：Gynecologic oncology

authors： Zamorano AS,Hagemann AR,Morrison L,Lee JA,Liao LM,Brinton LA,Park Y,Toriola AT

更新日期：2019-10-01 00:00:00

abstract：:A simple technique of closing the defect following simple vulvectomy is described. The labia minora as a pedicle graft avoids the problems encountered by conventional methods. ...

journal_title：Gynecologic oncology

authors： Trelford JD

更新日期：1974-12-01 00:00:00

abstract：OBJECTIVE:Bladder dysfunction caused by autonomic nerve injury is a well-recognized complication of pelvic surgery. Modified posterior exenteration with or without nerve preservation was performed in patients with primary ovarian, tubal, peritoneal, and endometrial cancer. The aim of this retrospective study was to eva...

journal_title：Gynecologic oncology

authors： Kato K,Tate S,Nishikimi K,Shozu M

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Epidemiologic data suggest that aberrant androgen homeostasis may promote aggressive epithelial ovarian cancer biology. Hyperandrogenism results from both obesity and expression of polymorphic androgen receptor (AR) allelotypes harboring short cytosine-adenine-guanine (CAG) repeat sequences; both have been sh...

journal_title：Gynecologic oncology

authors： Li AJ,Elmore RG,Pavelka JC,Karlan BY

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of non-hormonal, hyaluronic acid (HLA)-based vaginal gel in improving vulvovaginal estrogen-deprivation symptoms in women with a history of endometrial cancer. METHODS:For this single-arm, prospective, longitudinal trial, we enrolled disease-free women with a history of endometrial can...

journal_title：Gynecologic oncology

authors： Carter J,Goldfarb S,Baser RE,Goldfrank DJ,Seidel B,Milli L,Saban S,Stabile C,Canty J,Gardner GJ,Jewell EL,Sonoda Y,Kollmeier MA,Alektiar KM

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Different histologic types of epithelial ovarian cancer may represent different diseases with unique clinical and molecular characteristics. Clear cell carcinoma (CCC) of the ovary has been reported as having a worse prognosis than high grade serous epithelial ovarian cancer (EOC). This article critically rev...

journal_title：Gynecologic oncology

authors： del Carmen MG,Birrer M,Schorge JO

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this article is to review the data, rationale, and recommendations of vaginal brachytherapy (VBT) in the post-operative treatment of endometrial cancer patients. METHODS:The authors performed a thorough review of the medical literature regarding the use of adjuvant VBT in the treatment of endo...

journal_title：Gynecologic oncology

authors： Harkenrider MM,Block AM,Siddiqui ZA,Small W Jr

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:ABCB1 encodes the multi-drug efflux pump P-glycoprotein (P-gp) and has been implicated in multi-drug resistance. We comprehensively evaluated this gene and flanking regions for an association with clinical outcome in epithelial ovarian cancer (EOC). METHODS:The best candidates from fine-mapping analysis of 2...

journal_title：Gynecologic oncology

authors： Johnatty SE,Beesley J,Gao B,Chen X,Lu Y,Law MH,Henderson MJ,Russell AJ,Hedditch EL,Emmanuel C,Fereday S,Webb PM,Australian Ovarian Cancer Study Group.,Goode EL,Vierkant RA,Fridley BL,Cunningham JM,Fasching PA,Beckmann

更新日期：2013-10-01 00:00:00

abstract：:Eight patients with cervical intraepithelial neoplasia (CIN) were administered perilesional injections of human recombinant interferon gamma (IFN-gamma), and the response was evaluated by colposcopy and exfoliative cytology and then by histopathology. In all patients, colposcopic and cytologic findings improved after ...

journal_title：Gynecologic oncology

authors： Iwasaka T,Hayashi Y,Yokoyama M,Hachisuga T,Sugimori H

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to evaluate the clinical characteristics of clear cell carcinoma of the ovary. METHODS:Between 1986 and 1996, 45 patients with clear cell carcinoma of the ovary were identified by scanning the medical records department and the tumor registry at our institution. RESULTS:Median age w...

journal_title：Gynecologic oncology

authors： Behbakht K,Randall TC,Benjamin I,Morgan MA,King S,Rubin SC

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Recurrence of endometrial cancer in the brain is a rare event generally accompanied by limited life expectancy. We present an unusual case of long-term survival following surgical resection of an intracranial endometrial cancer metastasis. CASE:The present case is a patient with FIGO stage IIB, grade III en...

journal_title：Gynecologic oncology

authors： Elliott KS,Borowsky ME,Lee YC,Rao C,Abulafia O

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:Small cell carcinoma (SmCC) of the female genital tract constitutes a diagnostic and clinical challenge given its rarity and the lack of standardized therapeutic approaches. Here we review the morphological, clinical and molecular features of gynecologic SmCCs and discuss potential areas for future research. ...

journal_title：Gynecologic oncology

authors： Atienza-Amores M,Guerini-Rocco E,Soslow RA,Park KJ,Weigelt B

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:We assessed neoadjuvant intraarterial chemotherapy (NAC) followed by radical hysterectomy and/or radiotherapy in patients with locally advanced cervical cancer. METHODS:Over 5 years, 48 consecutive women with International Federation of Gynecology and Obstetrics stage IIb-IVa cervical cancer were enrolled. ...

journal_title：Gynecologic oncology

authors： Sugiyama T,Nishida T,Hasuo Y,Fujiyoshi K,Yakushiji M

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Metastatic bone involvement in vulvar squamous carcinoma is very rare. Here, we present a case of primary adenocarcinoma of the Bartholin's gland giving rise to isolated skull metastasis. CASE:A 74-year-old woman was referred with a diagnosis of primary vulvar adenocarcinoma of the right labium minus. A rig...

journal_title：Gynecologic oncology

authors： Ferrandina G,Testa AC,Zannoni GF,Poerio A,Scambia G

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Chemotherapy remains an essential part of the treatment of advanced ovarian cancer. Intraperitoneal (IP) administration has been demonstrated to provide a survival advantage over intravenous chemotherapy in three phase 3 studies. However, IP catheter complications have been a significant factor in aborting I...

journal_title：Gynecologic oncology

authors： Bryant CS,Shah JP,Triest JA,Schimp VL,Morris RT

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:The purpose of the present study is to prospectively evaluate the effects of tamoxifen on the pathological behavior of endometrial hyperplasias without atypia, diagnosed before the start of adjuvant endocrine therapy, in menopausal patients suffering from breast cancer. METHODS:Twenty-six patients suffering ...

journal_title：Gynecologic oncology

authors： Garuti G,Cellani F,Centinaio G,Sita G,Nalli G,Luerti M

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:The natural history of the development of ovarian carcinoma is not known. It also remains undetermined whether ovarian carcinomas develop from benign and/or borderline malignant tumors or arise de novo from the ovarian surface epithelium. METHODS:To address these issues clinicopathologically, we reviewed the...

journal_title：Gynecologic oncology

authors： Horiuchi A,Itoh K,Shimizu M,Nakai I,Yamazaki T,Kimura K,Suzuki A,Shiozawa I,Ueda N,Konishi I

更新日期：2003-03-01 00:00:00

abstract：:The pelvis is the predominant site of failure following radical radiotherapy (RT) for locally advanced cervical cancer. We report the results of phase I-II studies on 200 patients with bulky (greater than or equal to 5 cm) carcinoma of the cervix. Patients were treated between 1981 and 1988 on sequential protocols of ...

journal_title：Gynecologic oncology

authors： Thomas G,Dembo A,Fyles A,Gadalla T,Beale F,Bean H,Pringle J,Rawlings G,Bush R,Black B

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Angiomyolipoma is a distinctive benign neoplasm of the renal origin. Rare extrarenal instances of angiomyolipoma have been documented at various body sites. A case of extrarenal angiomyolipoma arising from the parametrial soft tissues is described in the present report. CASE:A woman, age 40 years, presented...

journal_title：Gynecologic oncology

authors： Chopra R,Al-Mulhim AR,Hashish H

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Patients with advanced epithelial ovarian cancer treated with salvage therapy using new combinations of systemic chemotherapy, radiation therapy, and systemic immunotherapy have had limited success. Since the most common site of relapse or failure to conventional systemic chemotherapy has been the peritoneal ...

journal_title：Gynecologic oncology

authors： Feun LG,Blessing JA,Major FJ,DiSaia PJ,Alvarez RD,Berek JS

更新日期：1998-12-01 00:00:00

abstract：:Of a group of 68 patients treated with standard polychemotherapy (CAP-5), 52 were evaluated by an early second-look laparotomy, preferably after three cycles of treatment. Of 21 patients with initial tumor residuals smaller than 2 cm, only 5 had residual tumor, and of 31 patients with tumor larger than 2 cm, 27 had re...

journal_title：Gynecologic oncology

authors： van Lith JM,Bouma J,Aalders JG,Boonstra H,Sleijfer DT,Willemse PH

更新日期：1989-11-01 00:00:00

abstract：:Angiogenesis is a proven clinical target for the treatment of advanced epithelial ovarian cancer. Vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs) offer patients potential new treatment regimens as they can be given as monotherapy, in combination with poly(ADP-ribose) polymerase (PAR...

journal_title：Gynecologic oncology

authors： Liu J,Nicum S,Reichardt P,Croitoru K,Illek B,Schmidinger M,Rogers C,Whalen C,Jayson GC

更新日期：2018-07-01 00:00:00

abstract：:Experience with the P.A.S.-PORT, a peripherally implanted central venous access device, is evaluated in a retrospective review of 154 patients from July 1991 to June 1994. Blood could not be aspirated from six patients. Complications included temporary minor thrombophlebitis in seven patients (4.5%), symptomatic axill...

journal_title：Gynecologic oncology

authors： Deppe G,Kahn ML,Malviya VK,Malone JM Jr,Christensen CW

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:The placental site trophoblastic tumor is a rare form of gestational trophoblastic disease. Fifteen percent of reported cases have been fatal, but predicting behavior in individual patients has been challenging. METHODS:The clinical, gross and histopathological features of 55 cases and 180 cases in the liter...

journal_title：Gynecologic oncology

authors： Baergen RN,Rutgers JL,Young RH,Osann K,Scully RE

更新日期：2006-03-01 00:00:00

abstract：:The finding of osseous metaplasia within an ovarian papillary serous cystadenocarcinoma is very rare. A review of the medical literature reveals only two previously published cases where mature bone was found in an ovarian serous cystadenocarcinoma. This report presents an additional case of this unusual phenomenon wh...

journal_title：Gynecologic oncology

authors： Bosscher J,Barnhill D,O'Connor D,Doering D,Nash J,Park R

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the safety, efficacy and impact on survival of low anterior resection and primary anastomosis at the time of en bloc resection for primary and recurrent epithelial ovarian carcinoma. METHODS:We performed a retrospective review of 46 primary and 14 recurrent epithelial ova...

journal_title：Gynecologic oncology

authors： Park JY,Seo SS,Kang S,Lee KB,Lim SY,Choi HS,Park SY

更新日期：2006-12-01 00:00:00