Primary bronchial and ovarian carcinoid tumors in the same patient: a case report and histopathologic analysis.

Abstract:

:The first case report of a 58-year-old woman with two different primary carcinoid tumors is presented. The bronchial carcinoid exhibited a mosaic pattern, whereas the ovarian tumor showed both insular and trabecular patterns. No teratomatous component was observed in the ovary. Both tumors presented an argyrophil reaction and neuron-specific enolase (NSE) immunoreactivity. The ovarian carcinoid contained a cell population of argentaffin and serotonin immunoreactive cells, while the bronchial carcinoid was unreactive. Peptide hormone immunostaining disclosed the presence of glucagon and pancreatic polypeptide (PP) in the bronchial carcinoid, whereas the ovarian carcinoid showed no immunoreactivity with the antisera used. The patient was treated surgically (bilobectomy of the right lung, 1978, and total abdominal hysterectomy and bilateral salpingo-oophorectomy, 1984) and is now well with normal blood chemistry, normal urinary HIAA, and normal routine X rays of the lungs and the gastrointestinal tract, as well as normal ultrasonography of the abdomen and the liver.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Sorbe B,Valentin K,Wilander E

doi

10.1016/0090-8258(86)90087-9

subject

Has Abstract

pub_date

1986-11-01 00:00:00

pages

355-62

issue

3

eissn

0090-8258

issn

1095-6859

journal_volume

25

pub_type

杂志文章
  • Radical hysterectomy followed by tailored postoperative therapy in the treatment of stage IB2 cervical cancer: feasibility and indications for adjuvant therapy.

    abstract:OBJECTIVE:To determine the outcome, complications and likelihood of requiring adjuvant therapy of patients with stage IB2 cervical cancer treated with primary radical hysterectomy and lymph node dissection. METHODS:Clinical and pathologic data between 1985 and 1999 were reviewed. Associations between clinical and path...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2004.04.016

    authors: Yessaian A,Magistris A,Burger RA,Monk BJ

    更新日期:2004-07-01 00:00:00

  • Inverse expression of Cdk4 and p16 in epithelial ovarian tumors.

    abstract:OBJECTIVES:The aim of this study was to elucidate the expression and the correlation of two cell cycle regulators, cdk4 and its inhibitor p16, in a series of benign, borderline, and malignant ovarian tumors and to evaluate whether their alterations correlate with clinicopathologial parameters and patients' prognosis in...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2000.5961

    authors: Sui L,Dong Y,Ohno M,Goto M,Inohara T,Sugimoto K,Tai Y,Hando T,Tokuda M

    更新日期:2000-11-01 00:00:00

  • Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy.

    abstract:OBJECTIVE:Our objective is to examine how selenium (Se) supplementation influences oxidative stress (malondialdehyde) and the glutathione peroxidase system in patients with ovarian cancer undergoing chemotherapy. MATERIAL:The study group included 31 patients with ovarian cancer undergoing chemotherapy receiving the dr...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.ygyno.2003.12.013

    authors: Sieja K,Talerczyk M

    更新日期:2004-05-01 00:00:00

  • Sacral metastasis in a patient with endometrial cancer: case report and review of the literature.

    abstract:BACKGROUND:Bone involvement in endometrial cancer has been described in less than 15% of the patients with metastatic disease. The medical literature reports 29 cases, although none involving the sacrum. CASE:We present a case of a 62-year-old woman who underwent surgery for endometrial adenocarcinoma in December 2002...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2008.04.005

    authors: Albareda J,Herrera M,Lopez Salva A,Garcia Donas J,Gonzalez R

    更新日期:2008-12-01 00:00:00

  • The incidence and risk factors associated with postoperative delirium in geriatric patients undergoing surgery for suspected gynecologic malignancies.

    abstract:BACKGROUND:The incidence of postoperative delirium (PD) in the elderly ranges between 3-60% but has never been examined in gynecologic oncology. Our goal was to identify pre, intra, and postoperative risk factors associated with the development of PD. METHODS:English speaking women of 60 years and above undergoing maj...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2008.02.016

    authors: McAlpine JN,Hodgson EJ,Abramowitz S,Richman SM,Su Y,Kelly MG,Luther M,Baker L,Zelterman D,Rutherford TJ,Schwartz PE

    更新日期:2008-05-01 00:00:00

  • Bilateral ultrastaging of sentinel lymph node in cervical cancer: Lowering the false-negative rate and improving the detection of micrometastasis.

    abstract:OBJECTIVE:To evaluate the sensitivity of sentinel node (SN) ultrastaging and to define parameters that may reduce the overall false-negative rate in women with early-stage cervical cancer. METHODS:We analyzed data from a large retrospective multicenter cohort group with FIGO stages IA-IIB cervical cancer in whom at le...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ygyno.2012.08.035

    authors: Cibula D,Abu-Rustum NR,Dusek L,Slama J,Zikán M,Zaal A,Sevcik L,Kenter G,Querleu D,Jach R,Bats AS,Dyduch G,Graf P,Klat J,Meijer CJ,Mery E,Verheijen R,Zweemer RP

    更新日期:2012-12-01 00:00:00

  • Routine lymph node dissection in the treatment of early stage cancer: are we doing the right thing?

    abstract::The role of elective lymphadenectomy in the treatment of patients with early-stage malignancies, although still commonly performed, remains a matter of controversy. This issue is important in the management of cancers and raises questions about the biologic interpretation of their natural history and about motives for...

    journal_title:Gynecologic oncology

    pub_type: 社论

    doi:10.1006/gyno.1997.4900

    authors: Santin AD,Parham GP

    更新日期:1998-01-01 00:00:00

  • Cloacogenic adenocarcinoma of the vulva.

    abstract::Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterized by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin histochemistry of en...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1999.5433

    authors: Willén R,Békássy,Carlén B,Bozoky B,Cajander S

    更新日期:1999-08-01 00:00:00

  • Concordance of DNA ploidy pattern as measured by flow cytometry in primary, metastatic, and persistent ovarian carcinoma.

    abstract::In an attempt to evaluate the stability of DNA content in ovarian carcinoma, 66 tumor specimens from 25 patients with stage III disease were analyzed by flow cytometry. For all patients, both primary tumor and omental metastasis were available, and for 16 patients the persistent tumor found at second-look operation wa...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1996.0027

    authors: Zanetta GM,Keeney GL,Kimlinger TK,Katzmann JA,Podratz KC

    更新日期:1996-02-01 00:00:00

  • Therapeutic effect of a radiolabeled monoclonal antibody on human ovarian cancer xenograft in nude mice.

    abstract::The therapeutic value of 131I-OC125, a radiolabeled monoclonal antibody directed against a human ovarian tumor associated antigen CA125, was examined in an ascites forming intraperitoneal human ovarian carcinoma nude mouse model. Nude mice were injected intraperitoneally with NIH:OVCAR3 cells. Twenty-one days after tu...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(89)90643-4

    authors: Manetta A,Satyaswaroop PG,Hamilton T,Ozols R,Mortel R

    更新日期:1989-03-01 00:00:00

  • Radical hysterectomy for recurrent cervical cancer following radiation therapy.

    abstract::In patients with small central recurrences following radiation therapy for cervical cancer the surgeon may have to make a judgment as to when radical hysterectomy is preferable to exenteration. During the years 1968-1984 there were 21 radical hysterectomies performed at Memorial Sloan-Kettering Cancer Center for recur...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(87)90252-6

    authors: Rubin SC,Hoskins WJ,Lewis JL Jr

    更新日期:1987-07-01 00:00:00

  • FDG-PET in the detection of recurrence of uterine cervical carcinoma following radiation therapy--tumor volume and FDG uptake value.

    abstract:PURPOSE:We evaluated the use of positron emission tomography (PET) with fluorine-18-labeled fluoro-2-deoxy-d-glucose (FDG) in follow-up study after radiation therapy in patients with uterine cervical carcinoma. MATERIALS AND METHODS:Thirty-two studies in 25 patients were reviewed. Twenty patients were treated with ext...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2005.09.030

    authors: Sakurai H,Suzuki Y,Nonaka T,Ishikawa H,Shioya M,Kiyohara H,Katoh H,Nakayama Y,Hasegawa M,Nakano T

    更新日期:2006-03-01 00:00:00

  • Endometrial cancer surgery in Arizona: a statewide analysis of access to care.

    abstract:OBJECTIVES:To investigate access to surgical care for endometrial cancer in Arizona. METHODS:The Arizona HealthQuery (AZHQ) data warehouse with claims information on over 7 million patients in Arizona was searched using the International Classification of Disease (ICD-9) codes and Current Procedural Terminology (CPT) ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2010.11.028

    authors: Benjamin I,Dalton H,Qiu Y,Cayco L,Johnson WG,Balducci J

    更新日期:2011-04-01 00:00:00

  • A phase II trial of didemnin B (NSC No. 325319) in advanced and recurrent cervical carcinoma: a Gynecologic Oncology Group study.

    abstract::Didemnin B was administered to 24 women with recurrent squamous cell cervical carcinoma. The initial dose was 4.2 mg/m2, intravenously, repeated every 28 days. Twenty-three patients were evaluable for toxicity and twenty-one for response. Toxicity was mild, consisting mainly of nausea and vomiting. There were no objec...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0090-8258(92)90055-n

    authors: Jacobs AJ,Blessing JA,Munoz A

    更新日期:1992-03-01 00:00:00

  • Long-term survival with advanced ovarian cancer: an analysis of 5-year survivors in the Australian trial comparing combination versus sequential chlorambucil and cisplatin therapy.

    abstract::Of 369 patients with apparent advanced ovarian cancer entered on a randomized trial between September 1979 and June 1983, 56 survived more than 5 years. Central pathology review confirmed the diagnosis in 318 cases (15 cases not ovarian primary, 36 slides did not reach central review). Two hundred ninety-eight were in...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0090-8258(92)90129-7

    authors: Tattersall MH,Swanson CE,Solomon HJ

    更新日期:1992-12-01 00:00:00

  • Paclitaxel and cisplatin in advanced or recurrent carcinoma of the endometrium: long-term results of a phase II multicenter study.

    abstract:OBJECTIVES:Both paclitaxel and cisplatin have moderate activity in patients with metastatic or recurrent carcinoma of the endometrium, and the combination of these two agents has shown activity in a variety of solid tumors. We administered this combination to patients with metastatic or recurrent carcinoma of the endom...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1006/gyno.2000.5827

    authors: Dimopoulos MA,Papadimitriou CA,Georgoulias V,Moulopoulos LA,Aravantinos G,Gika D,Karpathios S,Stamatelopoulos S

    更新日期:2000-07-01 00:00:00

  • An ultrastructural comparison of grade I and II endometrial adenocarcinoma considering estrogen and progesterone receptor status.

    abstract::Eighteen (18) previously untreated patients with grade I (9) and II (9) endometrial adenocarcinoma provided endometrial samples for biochemical analysis of estrogen and progesterone receptors. The same samples were evaluated by histology and ultrastructure. Progesterone receptor negative samples (PR less than 1000 fmo...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/0090-8258(84)90022-2

    authors: Horbelt DV,Freedman RS,Roberts DK,Walker NJ,Edwards CL,Jones LA

    更新日期:1984-06-01 00:00:00

  • Prognostic significance of hysteroscopic imaging in endometrioid endometrial adenocarcinoma.

    abstract:OBJECTIVE:The aim of this study was to relate hysteroscopic features of endometrioid endometrial adenocarcinoma to stage, grade and overall survival. METHODS:Sixty women with endometrioid adenocarcinoma underwent laparotomy and staging according to current FIGO classification. Before surgery hysteroscopy was performed...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6173

    authors: Garuti G,De Giorgi O,Sambruni I,Cellani F,Luerti M

    更新日期:2001-06-01 00:00:00

  • Role of integrins in invasion of endometrial cancer cell lines.

    abstract:OBJECTIVE:The objective of this study was to determine whether there is a link between integrins and components of the plasminogen system, regarding tumor cell invasion to the artificial extracellular matrix. METHODS:Immunocytochemistry was performed with antibodies directed against integrins alpha2beta1, alpha4beta1,...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2001.6410

    authors: Prifti S,Zourab Y,Koumouridis A,Bohlmann M,Strowitzki T,Rabe T

    更新日期:2002-01-01 00:00:00

  • Carboplatin and paclitaxel for advanced and recurrent cervical carcinoma: the British Columbia Cancer Agency experience.

    abstract:BACKGROUND:One of the most active chemotherapy combinations in advanced or recurrent cervical cancer is cisplatin-paclitaxel. However, this palliative regimen is associated with significant toxicity. Carboplatin-paclitaxel is thus an attractive option. METHODS:Patients with advanced or recurrent carcinoma of the cervi...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2005.03.037

    authors: Tinker AV,Bhagat K,Swenerton KD,Hoskins PJ

    更新日期:2005-07-01 00:00:00

  • Control of cyclin D1 expression by antisense oligonucleotides in three ovarian cancer cell lines.

    abstract::Cyclin D1 is a critical gene controlling the G1 phase progression through the cell cycle. Alterations of cyclin D1 have been demonstrated in a variety of cancer types. We recently reported that increased cyclin D1 expression is associated with malignancy also in ovarian tumors. Three human ovarian cancer cell lines (S...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1998.5062

    authors: Cagnoli M,Barbieri F,Bruzzo C,Alama A

    更新日期:1998-09-01 00:00:00

  • Postoperative outcomes after continent versus incontinent urinary diversion at the time of pelvic exenteration for gynecologic malignancies.

    abstract:OBJECTIVE:To compare outcomes of patients undergoing continent or incontinent urinary diversion after pelvic exenteration for gynecologic malignancies. METHODS:Data on patients who underwent pelvic exenteration for gynecologic malignancies at The University of Texas MD Anderson Cancer Center between January 1993 and D...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2013.02.024

    authors: Urh A,Soliman PT,Schmeler KM,Westin S,Frumovitz M,Nick AM,Fellman B,Urbauer DL,Ramirez PT

    更新日期:2013-06-01 00:00:00

  • Laparoscopically assisted Schauta operation: learning experience at the Gynecologic Oncology Unit, Buenos Aires University Hospital.

    abstract:OBJECTIVES:The aim of this study was to show the learning experience of the employment of laparoscopic lymphadenectomy followed by a Schauta operation to treat patients with cervical carcinoma at a university hospital and to evaluate the feasibility, complications, hospital stay, delay in return to work, and overall su...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1999.5588

    authors: Sardi J,Vidaurreta J,Bermúdez A,di Paola G

    更新日期:1999-12-01 00:00:00

  • The effect of medroxyprogesterone acetate on angiogenesis in complex endometrial hyperplasia.

    abstract:OBJECTIVE:To evaluate the effect of orally administered medroxyprogesterone acetate upon angiogenesis in the myometrium of patients with complex endometrial hyperplasia. METHODS:Microvessel counts in the myometrium of consecutive patients with complex endometrial hyperplasia, treated with oral medroxyprogesterone acet...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.1998.5106

    authors: Abulafia O,Triest WE,Adcock JT,Sherer DM

    更新日期:1999-02-01 00:00:00

  • Technique for precaval and laterocaval nodes excision at extraperitoneal paraaortic lymphadenectomy.

    abstract:STUDY OBJECTIVE:To describe our technique for excision of the pre-caval and laterocaval nodes using an extraperitoneal approach. This technique was developed to make the dissection and excision of the less accessible nodes in an easier and safer way by minimizing the risk of great vessels injury and bleeding. DESIGN:S...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2017.10.030

    authors: Gorostidi M,Villalain C,Ruiz R,Jaunarena I,Lekuona A

    更新日期:2018-01-01 00:00:00

  • Do differences in medical comorbidities and treatment impact racial disparities in epithelial ovarian cancer?

    abstract:BACKGROUND:Population-based studies of women with epithelial ovarian cancer suggest that black women have worse survival compared to white women. The primary objective of this study was to determine if, at a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center (CCC) serving a diverse racial and socioe...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2017.10.035

    authors: Dilley S,Erickson BK,Phillips CE,Kennemer CR,Zhang B,Matin T,Martin JY,Shah MM,Michael Straughn J Jr,Leath CA 3rd

    更新日期:2018-04-01 00:00:00

  • Osteomalacia due to chemotherapy-induced Fanconi syndrome in an adult patient.

    abstract:BACKGROUND:Chemotherapy-induced Fanconi syndrome is a dangerous condition that could lead to severe electrolyte disturbances and rarely to osteomalacia. CASE:A patient treated with ifosfamide for a metastatic cervix squamous-cell carcinoma was admitted for diffuse, symmetric bilateral pain in bones and articulations. ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2005.05.014

    authors: Duck L,Devogelaer JP,Persu A,Berlière M,Caussin E,Baurain JF,Machiels JP

    更新日期:2005-08-01 00:00:00

  • The efficacy of concurrent weekly carboplatin with radiotherapy in the treatment of cervical cancer: A meta-analysis.

    abstract:OBJECTIVES:We aimed to evaluate whether carboplatin has a comparable efficacy with cisplatin as part of weekly concurrent chemoradiotherapy for cervical cancer (Car-RT vs. Cis-RT). METHODS:A literature search was conducted and both prospective and retrospective studies that evaluated the efficacy of Car-RT for cervica...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ygyno.2018.07.005

    authors: Xue R,Cai X,Xu H,Wu S,Huang H

    更新日期:2018-09-01 00:00:00

  • Bokhman Redux: Endometrial cancer "types" in the 21st century.

    abstract::In 1983 Jan V. Bokhman, M.D. published a landmark paper entitled "Two Pathogenetic Types of Endometrial Carcinoma" in which an enduring dualistic view of endometrial cancer was first proposed. "Type I" cancers are thought to represent estrogen driven mostly low grade endometrioid tumors strongly associated with obesit...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1016/j.ygyno.2016.12.010

    authors: Suarez AA,Felix AS,Cohn DE

    更新日期:2017-02-01 00:00:00

  • Pattern of lymph node metastases in clinically unilateral stage I invasive epithelial ovarian carcinomas.

    abstract:PURPOSE:There is controversy regarding the pattern of lymphatic spread in unilateral stage I invasive ovarian carcinomas. The purpose of this study is to describe the incidence and distribution of lymph node (LN) metastases in ovarian carcinomas clinically confined to one ovary. METHODS:Ninety-six patients with diseas...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章

    doi:10.1006/gyno.2000.6027

    authors: Cass I,Li AJ,Runowicz CD,Fields AL,Goldberg GL,Leuchter RS,Lagasse LD,Karlan BY

    更新日期:2001-01-01 00:00:00