Increased frequency of complete hydatidiform mole in women with repeated abortion.

abstract：OBJECTIVES:The purpose of this study was to determine whether thromboembolic events (TE) in cervical cancer patients are associated with survival by comparing the survival of patients with and without thromboembolic events over a seven year period. METHODS:Utilizing a retrospective chart review we identified patients ...

journal_title：Gynecologic oncology

authors： Jacobson G,Lammli J,Zamba G,Hua L,Goodheart MJ

更新日期：2009-05-01 00:00:00

abstract：:Primary vaginal melanoma is an aggressive and rare gynecological malignancy with < 150 reported cases to date. Historically, patients with this disease have a poor prognosis for all types of treatment. In several studies containing small numbers of patients conservative therapy often has been recommended. Eight patien...

journal_title：Gynecologic oncology

authors： Van Nostrand KM,Lucci JA 3rd,Schell M,Berman ML,Manetta A,DiSaia PJ

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Placental-site trophoblastic tumor (PSTT) is the rarest form of gestational trophoblastic disease (GTD). A risk-adapted treatment approach has been advocated, but controversy exists as to the most important prognostic markers for this disease. Our goal was to determine the prognostic markers for patients with...

journal_title：Gynecologic oncology

authors： Hyman DM,Bakios L,Gualtiere G,Carr C,Grisham RN,Makker V,Sonoda Y,Aghajanian C,Jewell EL

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy, feasibility and safety of image-based, inversely and adaptively planned high-dose rate interstitial brachytherapy (HDR-ISBT) to treat advanced primary or recurrent gynecologic malignancy in a single implant, three-consecutive-day regimen. METHODS:Clinical demographics and outcome da...

journal_title：Gynecologic oncology

authors： Hanania AN,Myers P,Yoder AK,Bulut A,Henry Yu Z,Eraj S,Bowers J,Bonnen MD,Echeverria A,Hall TR,Anderson ML,Ludwig M

更新日期：2019-02-01 00:00:00

abstract：:Advances in surgery and chemotherapy have improved the 5-year survival for patients with epithelial ovarian cancer, but have not impacted on the ultimate rate of cure in a disease that is diagnosed in late stage and that recurs in the majority of patients. "Omic" technologies promise to define genetically driven aberr...

journal_title：Gynecologic oncology

authors： Ashworth A,Balkwill F,Bast RC,Berek JS,Kaye A,Boyd JA,Mills G,Weinstein JN,Woolley K,Workman P

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To estimate the survival benefit and cost-effectiveness of performing hysterectomy during risk-reducing salpingo-oophorectomy (RRSO) for BRCA1 mutation carriers. METHODS:Based on a recent prospective cohort study indicating an elevated incidence of serous/serous-like uterine cancers among BRCA1 mutation carr...

journal_title：Gynecologic oncology

authors： Havrilesky LJ,Moss HA,Chino J,Myers ER,Kauff ND

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Paclitaxel is most commonly infused over 3 hs rather than the original schedule of 24 h as the briefer infusion duration results in greater convenience, similar efficacy, significantly less myelosuppression, and less cost. While differences in toxicity between 3- and 24-h infusions are well described, there i...

journal_title：Gynecologic oncology

authors： Jennens R,Rischin D,Yuen K,Toner G,Millward M

更新日期：2003-10-01 00:00:00

abstract：:For the past several years, all women with epithelial ovarian cancer have been treated identically, whether in a clinical trial or off protocol. Over the past decade, we have come to appreciate the magnitude of the heterogeneity of ovarian cancer. The development of the binary grading system for serous carcinoma was a...

journal_title：Gynecologic oncology

authors： Romero I,Sun CC,Wong KK,Bast RC Jr,Gershenson DM

更新日期：2013-09-01 00:00:00

abstract：:The existing means of detecting recurrent ovarian carcinoma are notoriously poor. Positron emission tomography (PET) is a form of computer-assisted imaging which produces images reflective of the biochemistry of the tissues rather than their physical characteristics. PET imaging with the positron emitting glucose anal...

journal_title：Gynecologic oncology

authors： Karlan BY,Hawkins R,Hoh C,Lee M,Tse N,Cane P,Glaspy J

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:Describing the pattern of and reasons for post-operative tumor residuals in patients with advanced epithelial ovarian cancer (AOC) operated in a specialized gynecologic cancer center following a strategy of maximum upfront debulking followed by systemic chemotherapy. METHODS:All consecutive AOC-patients trea...

journal_title：Gynecologic oncology

authors： Heitz F,Harter P,Alesina PF,Walz MK,Lorenz D,Groeben H,Heikaus S,Fisseler-Eckhoff A,Schneider S,Ataseven B,Kurzeder C,Prader S,Beutel B,Traut A,du Bois A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:To estimate healthcare resource utilization and costs of cervical, vulvar and vaginal cancers in a large U.S. health plan. METHODS:We estimated incremental ambulatory visits, hospitalizations, prescription fills and healthcare costs for cancer cases relative to population controls. Data for cervical (n=2788...

journal_title：Gynecologic oncology

authors： Insinga RP,Ye X,Singhal PK,Carides GW

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the efficacy of a low-dose oral granisetron plus intravenous dexamethasone prophylactic antiemetic regimen in patients receiving carboplatin-based chemotherapy. PATIENTS AND METHODS:Patients with gynecologic malignancies being treated with either single-agent carb...

journal_title：Gynecologic oncology

authors： Markman M,Kennedy A,Webster K,Kulp B,Peterson G,Belinson J

更新日期：1998-10-01 00:00:00

abstract：:Verrucous carcinoma (VC) of the female genital tract is a rare lesion, primarily affecting postmenopausal women. A case of VC of the vulva is reported, bringing the total number of VC of the female genital tract to 89. VC is a slowly growing, locally "pushing" tumor with a rather benign histologic appearance, and the ...

journal_title：Gynecologic oncology

authors： Andersen ES,Sorensen IM

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:Oncolytic adenoviruses capable of replication selectively in tumor cells are an appealing approach for the treatment of neoplastic diseases refractory to conventional therapies. The aim of this study was to evaluate the effect of dose and scheduling of a tropism-modified, adenovirus serotype 3 receptor-target...

journal_title：Gynecologic oncology

authors： Raki M,Särkioja M,Desmond RA,Chen DT,Bützow R,Hemminki A,Kanerva A

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:In vitro data and pilot data suggest that green tea catechins may possess chemopreventive activity for cervical cancer and precursor lesions. We conducted a randomized, double-blind, placebo-controlled trial of Polyphenon E (decaffeinated and enriched green tea catechin extract) in women with persistent human...

journal_title：Gynecologic oncology

authors： Garcia FA,Cornelison T,Nuño T,Greenspan DL,Byron JW,Hsu CH,Alberts DS,Chow HH

更新日期：2014-02-01 00:00:00

abstract：:Nine years' experience with early uterine sarcoma is reviewed. In addition to hysterectomy and radiotherapy, 34 patients received adjunctive chemotherapy; 67 patients received no adjunctive chemotherapy. Seventeen patients who received chemotherapy received combination vincristine, 1.5 mg/m2 weekly; actinomycin D, 0.5...

journal_title：Gynecologic oncology

authors： Hannigan EV,Freedman RS,Rutledge FN

更新日期：1983-02-01 00:00:00

abstract：:As the medical need and expenditure for chronic wound care have increased markedly over the past decade, wound centers have grown exponentially throughout the country. They can be community-based or hospital-based, and in either case, can be run by the facility or by a national chain. The wound center's viability is d...

journal_title：Gynecologic oncology

authors： Attinger CE,Hoang H,Steinberg J,Couch K,Hubley K,Winger L,Kugler M

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to relate hysteroscopic features of endometrioid endometrial adenocarcinoma to stage, grade and overall survival. METHODS:Sixty women with endometrioid adenocarcinoma underwent laparotomy and staging according to current FIGO classification. Before surgery hysteroscopy was performed...

journal_title：Gynecologic oncology

authors： Garuti G,De Giorgi O,Sambruni I,Cellani F,Luerti M

更新日期：2001-06-01 00:00:00

abstract：:Relative and population attributable risks for invasive cervical cancer in different age strata relative to screening practices have been estimated using data from a case-control study conducted since 1981 in the greater Milan area, northern Italy. A total of 548 women under 75 years of age with a histologically confi...

journal_title：Gynecologic oncology

authors： Parazzini F,Negri E,La Vecchia C,Bocciolone L

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:Differentiation between grade-1 endometrial cancer (EC) and atypical endometrial hyperplasia (AEH) is crucial to determine optimal surgical management. However, discrepancies exist between preoperative diagnosis of AEH and final histology. Our aim was to establish clusters of immunohistochemical markers to d...

journal_title：Gynecologic oncology

authors： Laas E,Ballester M,Cortez A,Gonin J,Daraï E,Graesslin O

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:Australia's HPV vaccination and HPV-based cervical screening programs are changing the landscape in cervical cancer prevention. We aim to identify areas which can make the biggest further impact on cervical cancer burden. This protocol describes the first stage of a program of work called Pathways-Cervix that...

journal_title：Gynecologic oncology

authors： Velentzis LS,Smith MA,Simms KT,Lew JB,Hall M,Hughes S,Yuill S,Killen J,Keane A,Butler K,Darlington-Brown J,Hui H,Brotherton JML,Skinner R,Brand A,Roeske L,Heley S,Carter J,Bateson D,Frazer I,Garland SM,Guy R,H

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To investigate whether alteration of BRCA1 tumor suppressor gene occurs in sporadic endometrial carcinomas. METHODS:Genomic DNAs were prepared from 33 consecutively collected endometrial carcinoma tissues for BRCA1 mutational analysis. To screen for BRCA1 mutation, polymerase chain reaction (PCR) amplificati...

journal_title：Gynecologic oncology

authors： Liu FS,Ho ES,Shih RT,Shih A

更新日期：1997-09-01 00:00:00

abstract：:The role of elective lymphadenectomy in the treatment of patients with early-stage malignancies, although still commonly performed, remains a matter of controversy. This issue is important in the management of cancers and raises questions about the biologic interpretation of their natural history and about motives for...

journal_title：Gynecologic oncology

authors： Santin AD,Parham GP

更新日期：1998-01-01 00:00:00

abstract：:A 65-year-old woman had a total abdominal hysterectomy and bilateral salpingo-oophorectomy through a Pfannenstiel incision for a Stage Ib, Grade 2 endometrial adenocarcinoma with extension to the middle third of the myometrium. No adjuvant treatment was given. She presented 7 years later with a large suprapubic mass a...

journal_title：Gynecologic oncology

authors： Kotwall CA,Kirkbride P,Zerafa AE,Murray D

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVES:In this study we evaluated changes in serum Müllerian inhibiting substance (MIS) concentration in a large number of patients with granulosa cell tumors (GCT) to determine whether MIS is elevated at the time of presentation and whether MIS is an index of successful surgical resection and management of recurre...

journal_title：Gynecologic oncology

authors： Lane AH,Lee MM,Fuller AF Jr,Kehas DJ,Donahoe PK,MacLaughlin DT

更新日期：1999-04-01 00:00:00

abstract：:Near-infrared (NIR) fluorescence imaging has emerged as a promising complimentary technique for intraoperative visualization of tumor tissue, lymph nodes and vital structures. In this review, the current applications and future opportunities of NIR fluorescence imaging in gynecologic oncology are summarized. Several s...

journal_title：Gynecologic oncology

authors： Handgraaf HJ,Verbeek FP,Tummers QR,Boogerd LS,van de Velde CJ,Vahrmeijer AL,Gaarenstroom KN

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To describe the incidence of isolated paraaortic nodal metastasis in surgically staged endometrial cancer patients with negative pelvic lymph nodes. METHODS:Using a prospectively maintained database we identified all cases of endometrial cancer that had both pelvic and aortic nodal dissection and determined ...

journal_title：Gynecologic oncology

authors： Abu-Rustum NR,Gomez JD,Alektiar KM,Soslow RA,Hensley ML,Leitao MM Jr,Gardner GJ,Sonoda Y,Chi DS,Barakat RR

更新日期：2009-11-01 00:00:00

abstract：:Roughly one-third of patients with ataxia-telangiectasia (AT) develop malignant tumors, usually of lymphoid origin. AT patients also exhibit progeric changes. We describe three patients, between the ages of 27 and 32 years, with uterine tumors: one with a frank leiomyosarcoma and chronic T-cell leukemia, one with a mu...

journal_title：Gynecologic oncology

authors： Gatti RA,Nieberg R,Boder E

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVE:Early-phase data have demonstrated induction of antibody responses to a polyvalent vaccine conjugate (Globo-H, GM2, MUC1-TN, TF) with adjuvant OPT-821. We sought to determine if this combination decreases the hazard of progression or death compared to OPT-821 alone in patients with ovarian cancer in second/th...

journal_title：Gynecologic oncology

authors： O'Cearbhaill RE,Deng W,Chen LM,Lucci JA 3rd,Behbakht K,Spirtos NM,Muller CY,Benigno BB,Powell MA,Berry E,Tewari KS,Hanjani P,Lankes HA,Aghajanian C,Sabbatini PJ

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:We evaluated the activity and safety of the combination of topotecan, cisplatin and bevacizumab in patients with recurrent or persistent carcinoma of the cervix. METHODS:Eligible patients had persistent or recurrent cervical cancer not amenable to curative intent treatment. No prior chemotherapy for recurren...

journal_title：Gynecologic oncology

authors： Zighelboim I,Wright JD,Gao F,Case AS,Massad LS,Mutch DG,Powell MA,Thaker PH,Eisenhauer EL,Cohn DE,Valea FA,Alvarez Secord A,Lippmann LT,Dehdashti F,Rader JS

更新日期：2013-07-01 00:00:00