Increased glyceraldehyde-3-phosphate dehydrogenase gene expression in human cervical cancers.

abstract：OBJECTIVE:To analyze the expression of Heparanase, an enzyme involved in cancer metastasis and angiogenesis, in ovarian and breast carcinoma cells in effusions. METHODS:Heparanase protein expression was analyzed in malignant effusions from ovarian (=200) and breast (=41) carcinoma patients using immunocytochemistry. T...

journal_title：Gynecologic oncology

authors： Davidson B,Shafat I,Risberg B,Ilan N,Trope' CG,Vlodavsky I,Reich R

更新日期：2007-02-01 00:00:00

abstract：:Stains for mucosubstances were performed on endometrial curetting material of normal and pathological endometrium. The study included normal proliferative and secretory endometrium, cystic and adenomatous hyperplasia, and endometrial adenocarcinoma. It was attempted to characterize the epithelial mucin in each of thes...

journal_title：Gynecologic oncology

authors： Lurie M,Elmalach I,Weill S

更新日期：1988-06-01 00:00:00

abstract：:A case of high-grade endometrioid adenosquamous carcinoma of the ovary showing pilomatricoma-like areas and neuroendocrine differentiation is presented. The pilomatricoma-like areas were strongly positive for cytokeratin and vimentin, whereas the poorly differentiated areas of the tumor were positive for cytokeratin, ...

journal_title：Gynecologic oncology

authors： Fang J,Keh P,Katz L,Rao MS

更新日期：1996-05-01 00:00:00

abstract：:Leiomyosarcoma, a rare malignancy of smooth muscle, may arise from the retroperitoneum and present with the same vague symptoms as a malignancy of the pelvic organs. The purpose of this paper is to review eight cases of retroperitoneal leiomyosarcoma and to illustrate the presenting symptoms, prognostic indicators, an...

journal_title：Gynecologic oncology

authors： Todd CS,Michael H,Sutton G

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Hydroxysteroid-dehydrogenase-17b (HSD17b) genes control the last step in estrogen biosynthesis. The isoenzymes HSD17b2 and HSD17b4 in the uterus preferentially catalyze the conversion of estradiol, the most potent and active form of estrogen, to estrone, the inactive form of estrogen. Endometrial adenocarcino...

journal_title：Gynecologic oncology

authors： Karageorgi S,McGrath M,Lee IM,Buring J,Kraft P,De Vivo I

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Describing the pattern of and reasons for post-operative tumor residuals in patients with advanced epithelial ovarian cancer (AOC) operated in a specialized gynecologic cancer center following a strategy of maximum upfront debulking followed by systemic chemotherapy. METHODS:All consecutive AOC-patients trea...

journal_title：Gynecologic oncology

authors： Heitz F,Harter P,Alesina PF,Walz MK,Lorenz D,Groeben H,Heikaus S,Fisseler-Eckhoff A,Schneider S,Ataseven B,Kurzeder C,Prader S,Beutel B,Traut A,du Bois A

更新日期：2016-05-01 00:00:00

abstract：:The carcinoembryonic antigen (CEA) in the cyst fluid of ovarian mucinous and serous tumors was investigated. The molecular weight and antigenicity of the CEA from both ovarian tumors were very similar to those of colon cancer CEA as determined by SDS electrophoresis and double immunodiffusion on agar plates. In the cy...

journal_title：Gynecologic oncology

authors： Tohya T,Iwamasa T,Maeyama M

更新日期：1986-03-01 00:00:00

abstract：:To identify women who find outpatient laser cervical surgery painful we designed a prospective observational study correlating surgical pain with multiple variables. The pain scoring systems were validated by comparing the subjective linear analogue score with an objective scoring method. The pain of surgery was compa...

journal_title：Gynecologic oncology

authors： Johnson N,Crompton AC

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:Early-phase data have demonstrated induction of antibody responses to a polyvalent vaccine conjugate (Globo-H, GM2, MUC1-TN, TF) with adjuvant OPT-821. We sought to determine if this combination decreases the hazard of progression or death compared to OPT-821 alone in patients with ovarian cancer in second/th...

journal_title：Gynecologic oncology

authors： O'Cearbhaill RE,Deng W,Chen LM,Lucci JA 3rd,Behbakht K,Spirtos NM,Muller CY,Benigno BB,Powell MA,Berry E,Tewari KS,Hanjani P,Lankes HA,Aghajanian C,Sabbatini PJ

更新日期：2019-12-01 00:00:00

abstract：:A primary malignant mixed Mullerian tumor (MMMT) was found in the wall of the rectum of a 67-year-old female. The uterus, fallopian tubes, and ovaries had been previously excised for benign disease. The tumor was associated with foci of benign endometriosis. A literature review of extragenital MMMTs indicates that the...

journal_title：Gynecologic oncology

authors： Chumas JC,Thanning L,Mann WJ

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVES:Lymphovascular space invasion (LVSI) is an independent risk factor for recurrence and poor survival in early-stage endometrioid endometrial cancer (EEC), but optimal adjuvant treatment is unknown. We aimed to compare the survival of women with early-stage EEC with LVSI treated postoperatively with observatio...

journal_title：Gynecologic oncology

authors： Beavis AL,Yen TT,Stone RL,Wethington SL,Carr C,Son J,Chambers L,Michener CM,Ricci S,Burkett WC,Richardson DL,Staley AS,Ahn S,Gehrig PA,Torres D,Dowdy SC,Sullivan MW,Modesitt SC,Watson C,Veade A,Ehrisman J,Havril

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:To determine the incidence and prognostic implications of positive mesorectal lymph nodes in patients undergoing total pelvic exenteration for recurrent gynecologic malignancies. METHODS:We performed a retrospective chart review of all patients who had undergone total pelvic exenteration for a gynecologic m...

journal_title：Gynecologic oncology

authors： Mourton SM,Chi DS,Sonoda Y,Alektiar KM,Venkatraman ES,Barakat RR,Abu-Rustum NR

更新日期：2006-03-01 00:00:00

abstract：:The common epithelial tumors of the human ovary have rarely been found in the gonads of intersex patients with gonadal dysgenesis or true hermaphroditism. This report describes a patient with ovarian serous cystadenocarcinoma and mixed gonadal dysgenesis (45,X/46,XY) and reviews other reported cases. Intersex patients...

journal_title：Gynecologic oncology

authors： Miller DS,Teng NN,Ballon SC

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:To determine if DNA ploidy, hormone receptors, vascular space invasion (VSI), perivascular lymphocytes (PVL), and the oncogenes HER-2/neu, p53, and bcl-2 are independent prognostic indicators for lymph node metastasis and cancer recurrence in clinical stage I endometrial carcinoma. METHODS:Among 349 patients...

journal_title：Gynecologic oncology

authors： Bell JG,Minnick A,Reid GC,Judis J,Brownell M

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:Caregiver burden, quality of life (QOL) and unmet needs are poorly understood, particularly at the end of life. We explored these issues in caregivers of women with ovarian cancer. PATIENTS AND METHODS:The Australian Ovarian Cancer Study (AOCS) is a prospective population-based study of women newly diagnosed w...

journal_title：Gynecologic oncology

authors： Butow PN,Price MA,Bell ML,Webb PM,deFazio A,Australian Ovarian Cancer Study Group.,Australian Ovarian Cancer Study Quality Of Life Study Investigators.,Friedlander M

更新日期：2014-03-01 00:00:00

abstract：:To test the association between cytotoxicity and in vitro cell cycle perturbations we systematically studied cell cycle perturbations after exposing human ovarian cancer cells to nine commonly used cytotoxic agents. Three principal patterns of cell cycle alterations were observed: a sequential S-G2/M block after expos...

journal_title：Gynecologic oncology

authors： Petru E,Sevin BU,Haas J,Ramos R,Perras J

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:To assess toxicity and efficacy of weekly high-dose methotrexate-etoposide (HD MTX-ETO) in high-risk gestational trophoblastic neoplasia (GTN). METHODS:Retrospective chart review of high-risk GTN patients treated with HD MTX-ETO (methotrexate 1000 mg/m² day 1, etoposide 100 mg/m² days 1 and 2, q 1 wk). RESU...

journal_title：Gynecologic oncology

authors： Han SN,Amant F,Leunen K,Devi UK,Neven P,Berteloot P,Vergote I

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:CD4(+)CD25(+) regulatory T-cells (Tregs), that express the transcription factor FOXP3, suppress effector T-cell populations and can enable tumour cells to evade the host immune response. In this study, we investigated the numbers of FOXP3(+) Tregs in the normal and malignat endometrium and examined potential...

journal_title：Gynecologic oncology

authors： Giatromanolaki A,Bates GJ,Koukourakis MI,Sivridis E,Gatter KC,Harris AL,Banham AH

更新日期：2008-08-01 00:00:00

abstract：:The rate of regression of the beta subunit of human chorionic gonadotropin in patients successfully treated by single-agent chemotherapy with methotrexate (MTX) for postmolar nonmetastatic gestational trophoblastic neoplasia (NMGTN) has not previously been described. In 21 patients with NMGTN treated with MTX, the rat...

journal_title：Gynecologic oncology

authors： Rotmensch J,Rosenshein NB,Block BS

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Uterine serous carcinoma (USC) is presumed to arise from endometrial intra-epithelial carcinoma (EIC), whereas tubo-ovarian high-grade serous carcinomas have similar precursor lesions in the Fallopian tube, i.e. serous tubal intra-epithelial carcinoma (STIC). The presence of Fallopian tube abnormalities and t...

journal_title：Gynecologic oncology

authors： Steenbeek MP,Bulten J,Snijders MPLM,Lombaers M,Hendriks J,van den Brand M,Kraayenbrink AA,Massuger LFAG,Sweegers S,de Hullu JA,Pijnenborg JMA,Küsters-Vandevelde HVN,Reijnen C

更新日期：2020-08-01 00:00:00

abstract：:The standard management of advanced-stage ovarian cancer has been a subject of debate, and much controversy remains as to whether patients should have primary cytoreductive surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval cytoreductive surgery. In addition, there is increasing evidence...

journal_title：Gynecologic oncology

authors： Gómez-Hidalgo NR,Martinez-Cannon BA,Nick AM,Lu KH,Sood AK,Coleman RL,Ramirez PT

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:To assess the ability of the Age-Adjusted Charlson Comorbidity Index (ACCI) to predict perioperative complications and survival in patients undergoing primary debulking for advanced epithelial ovarian cancer (EOC). METHODS:Data were analyzed for all patients with stage IIIB-IV EOC who underwent primary cytor...

journal_title：Gynecologic oncology

authors： Suidan RS,Leitao MM Jr,Zivanovic O,Gardner GJ,Long Roche KC,Sonoda Y,Levine DA,Jewell EL,Brown CL,Abu-Rustum NR,Charlson ME,Chi DS

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Ovarian sex cord stromal tumors are frequently hormonally active, and adult granulosa cell tumors often demonstrate estrogen receptor positivity. Thus, hormonal agents have been evaluated as potential treatments for advanced stage or recurrent adult granulosa cell tumors. CASE:Two cases of patients with rec...

journal_title：Gynecologic oncology

authors： Freeman SA,Modesitt SC

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Protease-activated receptor-2 (PAR-2) is a G-protein-coupled receptor that is cleaved and activated by trypsin and tryptase. There is evidence that PAR-2 contributes to tumor progression in stomach, colon, pancreas, prostate and breast cancer patients. However, the role of PAR-2 in cervical cancer is still un...

journal_title：Gynecologic oncology

authors： Sánchez-Hernández PE,Ramirez-Dueñas MG,Albarran-Somoza B,García-Iglesias T,del Toro-Arreola A,Franco-Topete R,Daneri-Navarro A

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to analyze our experience with colorectal function preservation at the time of pelvic exenteration. METHODS:Between January 1980 and December 2001, 201 pelvic exenterations for gynecologic malignancies were performed in our hospital. Ninety-eight were supralevator exenteration...

journal_title：Gynecologic oncology

authors： Moutardier V,Houvenaeghel G,Lelong B,Mokart D,Delpero JR

更新日期：2003-04-01 00:00:00

abstract：:Sentinel node mapping is increasingly being utilized for endometrial cancer staging. However, only limited evidence supporting the adoption of sentinel node mapping instead of conventional lymphadenectomy is still available. Here, we aimed to review the current evidence comparing sentinel node mapping and lymphadenect...

journal_title：Gynecologic oncology

authors： Bogani G,Murgia F,Ditto A,Raspagliesi F

更新日期：2019-06-01 00:00:00

abstract：:Clear-cell hidradenocarcinoma is a malignant tumor of sweat gland origin. It is most often found on the trunk, head, and extremities. This case report describes a rare occurrence of this tumor on the vulva of a young woman. The discovery of metastatic disease reflects the potentially aggressive nature of this tumor. ...

journal_title：Gynecologic oncology

authors： Messing MJ,Richardson MS,Smith MT,King L,Gallup DG

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:Early-stage epithelial ovarian cancer represents a prognostically heterogenous group. We studied prognostic factors in patients treated with adjuvant paclitaxel/carboplatin chemotherapy. METHODS:Data was extracted from 147 patients with FIGO stage IA/IB, grade 2/3 or stage IC/IIA (any grade) who underwent pr...

journal_title：Gynecologic oncology

authors： Bamias A,Karadimou A,Soupos N,Sotiropoulou M,Zagouri F,Haidopoulos D,Thomakos N,Rodolakis A,Antsaklis A,Dimopoulos MA

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the prevalence and types of complementary and alternative medicine (CAM) usage by women with gynecologic cancer in an outpatient midwestern university practice. METHODS:Any patient with a gynecologic cancer seen in the outpatient clinic of the gynecologic oncology divis...

journal_title：Gynecologic oncology

authors： Swisher EM,Cohn DE,Goff BA,Parham J,Herzog TJ,Rader JS,Mutch DG

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:Reduced Selenium-Binding Protein 1 (SELENBP1) expression was recently shown in multiple cancers. There is little information on the expression and function of SELENBP1 in cancer progression. In order to develop a better understanding of the role of SELENBP1 in ovarian cancer, our objective was to determine if...

journal_title：Gynecologic oncology

authors： Stammer K,Edassery SL,Barua A,Bitterman P,Bahr JM,Hales DB,Luborsky JL

更新日期：2008-04-01 00:00:00