Overexpression of kallikrein 10 in epithelial ovarian carcinomas.

abstract：:The interaction of human gestational choriocarcinoma cell line, SMT-cc1, with bovine vascular endothelial cells, CPAE, was examined in an in vitro coculture model. SMT-cc1 cells have urokinase-type plasminogen activator (uPA) on their cell surface, and more than half of the cell-associated uPA is enzymatically inactiv...

journal_title：Gynecologic oncology

authors： Sugimura M,Kobayashi H,Terao T

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to evaluate the efficacy of postoperative concurrent chemoradiotherapy (CCRT) and to investigate the recurrence and survival rates after adjuvant CCRT in high-risk early cervical cancer (stages IA2, IB, IIA) patients who were treated by radical hysterectomy and pelvic lymphadenectomy...

journal_title：Gynecologic oncology

authors： Ryu HS,Chun M,Chang KH,Chang HJ,Lee JP

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:(1) To determine the response rate of advanced, recurrent, or persistent carcinoma of the cervix to ifosfamide, paclitaxel, and carboplatin chemotherapy; (2) to determine the progression free interval and survival rate in patients treated with this regimen; (3) to describe the toxicities associated with this...

journal_title：Gynecologic oncology

authors： Downs LS Jr,Chura JC,Argenta PA,Judson PL,Ghebre R,Geller MA,Carson LF

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Vulvar reconstruction following oncologic resection is challenging. Some flaps used for reconstruction can show adverse characteristics such as excessive tissue bulk or increased distance to the defect. Region of the sulcus genitofemoralis is of thin and pliable tissue proximate to the vulva. Vasculature and ...

journal_title：Gynecologic oncology

authors： O'Dey DM,Bozkurt A,Pallua N

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:The efficacy and toxicity of neoadjuvant chemotherapy (NAC) with mitomycin-C, vincristine and cisplatin (MVC) were assessed in bulky cervical carcinoma patients. METHODS:Forty-six patients with stage IB2 to IIB cervical cancer were treated with intravenous combination of mitomycin-C 10 mg/m(2), vincristine 1...

journal_title：Gynecologic oncology

authors： Choi CH,Kim TJ,Lee JW,Kim BG,Lee JH,Bae DS

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Our objective is to examine how selenium (Se) supplementation influences oxidative stress (malondialdehyde) and the glutathione peroxidase system in patients with ovarian cancer undergoing chemotherapy. MATERIAL:The study group included 31 patients with ovarian cancer undergoing chemotherapy receiving the dr...

journal_title：Gynecologic oncology

authors： Sieja K,Talerczyk M

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To compare the frequencies of somatic homologous recombination (HR) gene mutations identified in next-generation sequencing (NGS) genomic profiling of uterine serous carcinomas (USCs) and high-grade serous ovarian carcinomas (HGSOCs). METHODS:Data for this analysis was obtained from AACR Project GENIE, a mul...

journal_title：Gynecologic oncology

authors： Wallbillich JJ,Morris RT,Ali-Fehmi R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between molecular subtype, intraperitoneal (IP) disease dissemination patterns, resectability, and overall survival (OS) in advanced high-grade serous ovarian cancer (HGSOC). METHODS:Patients undergoing primary surgery for stage III-IV HGSOC at Mayo Clinic from 1994 to 2011 we...

journal_title：Gynecologic oncology

authors： Torres D,Wang C,Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Konecny GE,Goode EL,Cliby WA

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To date, The Cancer Genome Atlas (TCGA) has provided the most extensive molecular characterization of invasive cervical cancer (ICC). Analysis of reverse phase protein array (RPPA) data from TCGA samples showed that cervical cancers could be stratified into 3 clusters exhibiting significant differences in sur...

journal_title：Gynecologic oncology

authors： Rader JS,Pan A,Corbin B,Iden M,Lu Y,Vellano CP,Akbani R,Mills GB,Simpson P

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Small cell carcinoma (SmCC) of the female genital tract constitutes a diagnostic and clinical challenge given its rarity and the lack of standardized therapeutic approaches. Here we review the morphological, clinical and molecular features of gynecologic SmCCs and discuss potential areas for future research. ...

journal_title：Gynecologic oncology

authors： Atienza-Amores M,Guerini-Rocco E,Soslow RA,Park KJ,Weigelt B

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Nongestational pure ovarian choriocarcinoma is a rare malignancy with only 29 cases described to date. CASE:We describe a case associated with mature cystic teratoma of the contralateral ovary. Details of all 30 cases including clinical features, associations, surgicopathological findings, operative procedu...

journal_title：Gynecologic oncology

authors： Goswami D,Sharma K,Zutshi V,Tempe A,Nigam S

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Radical vaginal trachelectomy (RVT) is an acceptable approach when applied toward a select group of patients with early stage cervical carcinoma. It is less invasive, can maintain fertility, and can be ideal in patients with significant comorbid factors compared to abdominal approaches. A small subset of pat...

journal_title：Gynecologic oncology

authors： Mendez LE,Penalver M,McCreath W,Bejarano P,Angioli R

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To determine whether intra-operative radiation therapy (IORT) at the time of pelvic exenteration (PE) or laterally extended endopelvic resection (LEER) improves progression-free survival (PFS) in patients with recurrent, previously irradiated gynecologic cancers. METHODS:We conducted a single institution ret...

journal_title：Gynecologic oncology

authors： Backes FJ,Billingsley CC,Martin DD,Tierney BJ,Eisenhauer EL,Cohn DE,O'Malley DM,Salani R,Copeland LJ,Fowler JM

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the optimal cytoreduction (OPT) rate, National Comprehensive Cancer Network (NCCN) treatment guideline compliance rate and patient outcomes for advanced stage epithelial ovarian cancer (EOC) patients at our low volume institution. METHODS:Following IRB approval, records of patients with Stage III...

journal_title：Gynecologic oncology

authors： Phippen NT,Barnett JC,Lowery WJ,Miller CR,Leath CA 3rd

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:Randomized trials have demonstrated significant improvements in progression-free survival (PFS) with consolidation paclitaxel (P) and bevacizumab (B) following cytoreduction and adjuvant carboplatin/paclitaxel (CP) for advanced epithelial ovarian cancer (EOC). We sought to evaluate the cost-effectiveness (...

journal_title：Gynecologic oncology

authors： Lesnock JL,Farris C,Krivak TC,Smith KJ,Markman M

更新日期：2011-09-01 00:00:00

abstract：:Symptomatic uterine lymphangioleiomyomatosis (LAM) simulating high-stage uterine sarcoma in a patient with tuberous sclerosis complex is reported. A 49-year-old female presented with abdominal pain and anemia. Preoperative workup revealed a uterine mass and a large amount of peritoneal free fluid and possible metastat...

journal_title：Gynecologic oncology

authors： Longacre TA,Hendrickson MR,Kapp DS,Teng NN

更新日期：1996-12-01 00:00:00

abstract：:Verrucous carcinoma (VC) of the female genital tract is a rare lesion, primarily affecting postmenopausal women. A case of VC of the vulva is reported, bringing the total number of VC of the female genital tract to 89. VC is a slowly growing, locally "pushing" tumor with a rather benign histologic appearance, and the ...

journal_title：Gynecologic oncology

authors： Andersen ES,Sorensen IM

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:To determine the impact of geographic location on advanced-stage ovarian cancer care adherence to the National Comprehensive Cancer Network (NCCN) guidelines in relation to race and socioeconomic status (SES). METHODS:Patients diagnosed with stage IIIC/IV epithelial ovarian cancer (1/1/96-12/31/06) were iden...

journal_title：Gynecologic oncology

authors： Bristow RE,Chang J,Ziogas A,Anton-Culver H,Vieira VM

更新日期：2014-07-01 00:00:00

abstract：:Vaginal evisceration is a rare event. This case report describes a 45-year-old woman who presented 8 days following radical hysterectomy and lymph node dissection for stage 1B squamous cell carcinoma of the cervix with small bowel evisceration through the vagina. She was treated by laparotomy and resection anastamosis...

journal_title：Gynecologic oncology

authors： Dawlatly B,Lavie O,Lopes A

更新日期：1999-04-01 00:00:00

abstract：:HIV infection among women is increasing in the United States. Since January 1993, cervical cancer has been considered an AIDS-defining illness. We report a rare case of squamous cell carcinoma arising in a teratoma of the uterine cervix in an HIV-infected patient. This patient was treated with a radical hysterectomy, ...

journal_title：Gynecologic oncology

authors： Bell MC,Schmidt-Grimminger DC,Connor MG,Alvarez RD

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of introducing a robotics program on clinical outcome of elderly patients with endometrial cancer. METHODS:Evaluation and comparison of peri-operative morbidity and disease-free interval in 163 consecutive elderly patients (≥70years) with endometrial cancer undergoing staging procedure...

journal_title：Gynecologic oncology

authors： Lavoue V,Zeng X,Lau S,Press JZ,Abitbol J,Gotlieb R,How J,Wang Y,Gotlieb WH

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to evaluate the clinical characteristics of clear cell carcinoma of the ovary. METHODS:Between 1986 and 1996, 45 patients with clear cell carcinoma of the ovary were identified by scanning the medical records department and the tumor registry at our institution. RESULTS:Median age w...

journal_title：Gynecologic oncology

authors： Behbakht K,Randall TC,Benjamin I,Morgan MA,King S,Rubin SC

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:Endometrial cancer mortality disproportionately affects black women and whether greater prevalence of obesity plays a role in this disparity is unknown. We examine the effect of race on post-surgical complications, length of stay, and mortality specifically in a morbidly obese population. METHODS:Black and w...

journal_title：Gynecologic oncology

authors： Cote ML,Ruterbusch JJ,Ahmed Q,Bandyopadhyay S,Alosh B,Abdulfatah E,Seward S,Morris R,Ali-Fehmi R

更新日期：2014-04-01 00:00:00

abstract：:To determine the morbidity associated with delivery of intraperitoneal chemotherapy via subcutaneous semipermanent infusion catheters, we analyzed the data on 227 patients treated from April 1985 through December 1989. A total of 249 catheters were inserted and used to administer chemotherapy in these patients. There ...

journal_title：Gynecologic oncology

authors： Davidson SA,Rubin SC,Markman M,Jones WB,Hakes TB,Reichman B,Almadrones L,Chapman D,Lewis JL Jr,Hoskins WJ

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVES:Fractal geometry is a tool used to characterize irregularly shaped and complex figures. It can be used not only to generate biological structures (e.g., the human renal artery tree), but also to derive parameters such as the fractal dimension in order to quantify the shapes of structures. As such, it allows ...

journal_title：Gynecologic oncology

authors： Sedivy R,Windischberger C,Svozil K,Moser E,Breitenecker G

更新日期：1999-10-01 00:00:00

abstract：:Fourteen patients underwent surgical debulking of diaphragmatic metastases as part of cytoreductive surgery for advanced ovarian epithelial cancer from 1983 to 1984. The surgical technique is described. Morbidity from this approach was not excessive in this small series of patients. It is suggested that this technique...

journal_title：Gynecologic oncology

authors： Deppe G,Malviya VK,Boike G,Hampton A

更新日期：1986-06-01 00:00:00

abstract：:Three hundred and sixty-two cases of primary vaginal carcinoma were treated at the Irradiation Department of the University Clinic for Obstetrics and Gynecology, Vienna, from 1950 to 1977. As the method of choice an individually dosed, fractioned, and protracted radium-telecobalt therapy was employed. Comparing the la...

journal_title：Gynecologic oncology

authors： Kucera H,Langer M,Smekal G,Weghaupt K

更新日期：1985-05-01 00:00:00

abstract：:Stage IIB-IV squamous cell carcinoma of the cervix when treated by irradiation has a significant failure rate. Causes of pelvic and distant failure are discussed. New techniques employed to improve local control and decrease distant metastasis are presented. Data on morbidity, mortality, and survival will be reviewed ...

journal_title：Gynecologic oncology

authors： Krochak R

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:It is well established that many human tumors can express somatostatin receptors. This is the molecular basis for the application of long-acting somatostatin analogues for therapeutic and diagnostic purposes. However, there are discrepancies in earlier studies regarding the prevalence of somatostatin receptor...

journal_title：Gynecologic oncology

authors： Schulz S,Schmitt J,Quednow C,Roessner A,Weise W

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:Describe clinical characteristics and risk reducing strategies utilized among women with a BRCA mutation who lived to age 75 and above. METHODS:A retrospective study of women with BRCA mutations identified from 1995 to 2015 in a California health care system. From a database of 1189 women, 69 participants we...

journal_title：Gynecologic oncology

authors： Salyer C,Kobelka C,Barrie A,Weintraub MR,Powell CB

更新日期：2019-08-01 00:00:00