Nongestational pure ovarian choriocarcinoma with contralateral teratoma.

abstract：OBJECTIVES:To evaluate the CINtec PLUS assay (mtm laboratories), a new immunocytochemical method for the simultaneous detection of p16(INK4a) and Ki-67, in liquid-based cervico-vaginal cytology, investigating the association of the dual staining with HPV infection and genotyping as well as cytological and histological ...

journal_title：Gynecologic oncology

authors： Donà MG,Vocaturo A,Giuliani M,Ronchetti L,Rollo F,Pescarmona E,Carosi M,Vocaturo G,Benevolo M

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To evaluate incidence, indications, and outcome of hysterectomy in women presenting with gestational trophoblastic disease. METHODS:A prospective observational study using a standardized protocol for registration, assessment, and treatment of gestational trophoblastic disease. A total of 5976 consecutive new...

journal_title：Gynecologic oncology

authors： Pisal N,North C,Tidy J,Hancock B

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Post-irradiation breast sarcoma is a rare and highly aggressive tumor, associated with poor prognosis. However, the mean latent periods reported for postradiation sarcomas after treatment of breast cancer ranges from 5 to 10 years. CASE:We present a rare case of fibrosarcoma of the axilla, diagnosed 23 mont...

journal_title：Gynecologic oncology

authors： Plotti F,Di Donato V,Zullo MA,Angioli R,Panici PB

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To identify patients with endometrial cancer at risk for hematogenous, lymphatic, or peritoneal recurrence (or combinations of them) who might potentially benefit from target-based therapies. METHODS:During a 13-year period, 915 patients had endometrial cancer managed with hysterectomy and standard adjuvant ...

journal_title：Gynecologic oncology

authors： Mariani A,Dowdy SC,Keeney GL,Long HJ,Lesnick TG,Podratz KC

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:To identify novel prognostic and therapeutic markers for PARP inhibitors in BRCA wild type ovarian cancer (OvCa). METHODS:BRCAness status was defined by analyzing whole-exome deep sequencing data from 220 BRCAwt OvCa cases in TCGA. Thirty-three DNA-repair genes were screened in an integrated manner for BRCA-...

journal_title：Gynecologic oncology

authors： Zhang M,Liu G,Xue F,Edwards R,Sood AK,Zhang W,Yang D

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:The ability to minimize residual disease during primary cytoreductive surgery is the strongest predictor for improved overall survival in advanced ovarian cancer. But while the probability to achieve a macroscopic complete resection increases if surgery is preceded by neoadjuvant chemotherapy (NACT), survi...

journal_title：Gynecologic oncology

authors： Timmermans M,van der Hel O,Sonke GS,Van de Vijver KK,van der Aa MA,Kruitwagen RF

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Metformin is one of the most widely used drugs for the treatment of type 2 diabetes. Recent investigations demonstrated that application of metformin reduces cancer risk. The present study aimed to determine the role of liver kinase B1 (LKB1) in the response of cervical cancer cells to metformin. METHODS:LKB...

journal_title：Gynecologic oncology

authors： Xiao X,He Q,Lu C,Werle KD,Zhao RX,Chen J,Davis BC,Cui R,Liang J,Xu ZX

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:Women with advanced-stage, low-grade serous ovarian carcinoma (LGSC) have low chemotherapy response rates and poor overall survival. Most LGSC tumors overexpress hormone receptors, which represent a potential treatment target. Our study objective was to determine the outcomes of patients with advanced-stage ...

journal_title：Gynecologic oncology

authors： Fader AN,Bergstrom J,Jernigan A,Tanner EJ 3rd,Roche KL,Stone RL,Levinson KL,Ricci S,Wethingon S,Wang TL,Shih IM,Yang B,Zhang G,Armstrong DK,Gaillard S,Michener C,DeBernardo R,Rose PG

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:The goal of this case review was to evaluate the influence of complete surgical versus clinical staging, including the impact of ovarian preservation, on the outcome of young patients with endometrial carcinoma. METHODS:A retrospective chart review was performed on all patients with endometrial cancer diagn...

journal_title：Gynecologic oncology

authors： Richter CE,Qian B,Martel M,Yu H,Azodi M,Rutherford TJ,Schwartz PE

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:In preparation for the launch of a gynecologic oncology survivorship program, this study looked at the informational needs of women with gynecologic cancers. Although studies have touched on some of these needs, no published literature has investigated the comprehensive informational needs of gynecologic onc...

journal_title：Gynecologic oncology

authors： Papadakos J,Bussière-Côté S,Abdelmutti N,Catton P,Friedman AJ,Massey C,Urowitz S,Ferguson SE

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:After treatment for ovarian cancer, women want to know when they will feel 'normal' again. Our objective was to document the proportions of women with high levels of physical and emotional symptoms at the end of treatment, determine if/when they return to normal and identify groups at risk of persistent symp...

journal_title：Gynecologic oncology

authors： Beesley VL,Webber K,Nagle CM,DeFazio A,Obermair A,Williams M,Friedlander M,Webb PM,OPAL Study Group.

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Radiation treatment is one of the most standardized and effective modalities for contemporary cervical cancer therapy. In addition, the radiation-potentiating effects of retinoic acid have been recently described. In order to investigate whether enhanced immunogenicity might be responsible for such potentiat...

journal_title：Gynecologic oncology

authors： Santin AD,Hermonat PL,Ravaggi A,Chiriva-Internati M,Hiserodt JC,Pecorelli S,Parham GP

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVES:The role of adjuvant therapy in patients with early stage ovarian carcinoma has not been clearly defined. Most randomized trials examining this issue have not used the vigorous staging exploration accepted as today's standard. This report examines the natural history of patients after surgically documented s...

journal_title：Gynecologic oncology

authors： Le T,Krepart GV,Lotocki RJ,Heywood MS

更新日期：1999-08-01 00:00:00

abstract：:Relative and population attributable risks for invasive cervical cancer in different age strata relative to screening practices have been estimated using data from a case-control study conducted since 1981 in the greater Milan area, northern Italy. A total of 548 women under 75 years of age with a histologically confi...

journal_title：Gynecologic oncology

authors： Parazzini F,Negri E,La Vecchia C,Bocciolone L

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Neuroendocrine carcinomas (NECs) of the cervix comprise only 2% of all cervical cancers. Prospective data is limited and treatment guidelines rely on retrospective reviews and literature from lung NEC. The objective of this study was to report our experience in the management of this rare disease. METHODS:T...

journal_title：Gynecologic oncology

authors： McCann GA,Boutsicaris CE,Preston MM,Backes FJ,Eisenhauer EL,Fowler JM,Cohn DE,Copeland LJ,Salani R,O'Malley DM

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:High-risk (HR) human papillomavirus (HPV) testing is important in cervical cancer screening for triage to colposcopy. This study evaluated the clinical performance of the Cervista HPV HR and 16/18 genotyping tests for detection of HPV in cervical cytology specimens. METHODS:The tests were prospectively evalu...

journal_title：Gynecologic oncology

authors： Einstein MH,Martens MG,Garcia FA,Ferris DG,Mitchell AL,Day SP,Olson MC

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of parametrial involvement in a select group of patients with early cervical cancer. METHODS:We retrospectively reviewed the records of patients with cervical cancer and a maximum tumor diameter of 2 cm, infiltration depth<10 mm and negative pelvic lymph nodes who underwent a radic...

journal_title：Gynecologic oncology

authors： Stegeman M,Louwen M,van der Velden J,ten Kate FJ,den Bakker MA,Burger CW,Ansink AC

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To estimate the frequency of cervical cytologic/histologic discrepancies in a group of obstetric patients diagnosed as HIV infected by routine prenatal screening. Also, to determine if serum CD4 levels or sexually transmitted diseases (STDs) are associated with the occurrence of preinvasive cervical disease i...

journal_title：Gynecologic oncology

authors： Robinson WR,Barnes SE,Adams S,Perrin MS

更新日期：1997-06-01 00:00:00

abstract：:A new cell line, CUMC-3, has been derived from an invasive nonkeratinizing squamous cell carcinoma of the uterine cervix in a 32-year-old patient. It has been maintained in long-term culture for 59 months, and passaged over 310 times. Monolayer-cultured cells were polygonal in shape, showing a pavement-like arrangemen...

journal_title：Gynecologic oncology

authors： Kim JW,Cho YH,Lyu MS,Lee CG,Jung JK,Kim SJ,Namkoong SE

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:Many investigators have studied the expression of G1 phase regulatory protein in uterine cervical cancer. However, it is unclear which step of the genetic expression participates in cyclin D1 expression and what its prognostic meaning is. The aims of this study were to evaluate the regulatory level of cyclin ...

journal_title：Gynecologic oncology

authors： Bae DS,Cho SB,Kim YJ,Whang JD,Song SY,Park CS,Kim DS,Lee JH

更新日期：2001-06-01 00:00:00

abstract：:The records of 125 patients with nonmucinous invasive ovarian adenocarcinoma who underwent cytoreductive surgery, cisplatin-based combination chemotherapy, and second-look laparotomy were analyzed to correlate pre-second-look serum CA-125 levels with the size of residual ovarian cancer. The majority of patients with n...

journal_title：Gynecologic oncology

authors： Patsner B,Orr JW Jr,Mann WJ Jr,Taylor PT,Partridge E,Allmen T

更新日期：1990-06-01 00:00:00

abstract：OBJECTIVES:The aims of the study were to investigate whether an elevated CA 125 level signals malignancies other than ovarian cancer and to find the cause of death for 247 women with elevated values among the 5550 women screened in 1986-1988 in the Stockholm population. METHODS:The Swedish Regional Cancer Registry del...

journal_title：Gynecologic oncology

authors： Sjövall K,Nilsson B,Einhorn N

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Angiomyolipoma is a distinctive benign neoplasm of the renal origin. Rare extrarenal instances of angiomyolipoma have been documented at various body sites. A case of extrarenal angiomyolipoma arising from the parametrial soft tissues is described in the present report. CASE:A woman, age 40 years, presented...

journal_title：Gynecologic oncology

authors： Chopra R,Al-Mulhim AR,Hashish H

更新日期：2003-07-01 00:00:00

abstract：:cis-Platinum is a chemotherapeutic agent with benefits often limited by the severe gastrointestinal reactions it produces in nearly all patients. Persistent anorexia, nausea, and vomiting may continue for days after therapy and are poorly controlled by conventional antiemetics. Patients at times refuse continuation of...

journal_title：Gynecologic oncology

authors： Benrubi GI,Norvell M,Nuss RC,Robinson H

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:To describe our experience with extraperitoneal lymph node staging in gynecologic oncology. MATERIALS AND METHODS:The extraperitoneal approach was performed to assess the lymph node histology in patients with gynecologic malignancies. The nodes are approached from a lateral approach after dissecting open th...

journal_title：Gynecologic oncology

authors： Burnett AF,O'Meara AT,Bahador A,Roman LD,Morrow CP

更新日期：2004-10-01 00:00:00

abstract：:Forty-eight cases subjected to radioimmunoimaging (RII) by intraperitoneal injection with 131I-C0C183B2 monoclonal antibody (MAb) prepared in our laboratory were studied. Thirteen of 14 cases of proved primary ovarian carcinoma were positive. In 11 follow-up cases of ovarian carcinoma after initial surgery and chemoth...

journal_title：Gynecologic oncology

authors： Qian H,Feng J,Cui H,Gao B,Qi G,Fu T,Wei P,Fu Z

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Women with cervical cancer constitute a patient population in need for ongoing, person-centred supportive care. Our aim was to synthesise current available evidence with regard to the supportive care needs of women living with and beyond cervical cancer. METHODS:A systematic review was conducted according t...

journal_title：Gynecologic oncology

authors： Maguire R,Kotronoulas G,Simpson M,Paterson C

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To examine the relative efficacy of cisplatin-based intraperitoneal (IP) therapy versus carboplatin-based IP therapy as salvage treatment of small-volume residual ovarian cancer. PATIENTS AND METHODS:We retrospectively examined the surgically defined response rates of patients with ovarian cancer treated at th...

journal_title：Gynecologic oncology

authors： Markman M,Reichman B,Hakes T,Rubin S,Lewis JL Jr,Jones W,Barakat R,Curtin J,Almadrones L,Hoskins W

更新日期：1993-07-01 00:00:00

abstract：:Homeobox (HOX) genes are a family of transcription factors that are essential regulators of development. HOX genes play important roles in normal reproductive physiology, as well as in the development and progression of serous carcinomas, the predominant and most aggressive subtype of epithelial ovarian cancer (EOC). ...

journal_title：Gynecologic oncology

authors： Miller KR,Patel JN,Ganapathi MK,Tait DL,Ganapathi RN

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:This article critically reviews the literature on the association between endometriosis and gynecological cancers and breast cancer, based on epidemiologic data. METHODS:Literature review of the English language literature based on searching in the MEDLINE (PubMed) database and additional collection of repor...

journal_title：Gynecologic oncology

authors： Munksgaard PS,Blaakaer J

更新日期：2011-10-01 00:00:00