An unusual case of secondary fibrosarcoma after treatment for breast cancer.

abstract：OBJECTIVE:Different histologic types of epithelial ovarian cancer may represent different diseases with unique clinical and molecular characteristics. Clear cell carcinoma (CCC) of the ovary has been reported as having a worse prognosis than high grade serous epithelial ovarian cancer (EOC). This article critically rev...

journal_title：Gynecologic oncology

authors： del Carmen MG,Birrer M,Schorge JO

更新日期：2012-09-01 00:00:00

abstract：:We performed a study to evaluate the relationships between the surgical stage (FIGO, 1989), histological tumor grade, myometrial invasion, peritoneal cytology, lymph node metastasis and prognosis, and DNA ploidy determined by flow cytometry in paraffin-embedded blocks of resected cancer lesions from 76 patients with u...

journal_title：Gynecologic oncology

authors： Ikeda M,Watanabe Y,Nanjoh T,Noda K

更新日期：1993-07-01 00:00:00

abstract：:Ovarian, endometrial and cervical cancers are the most prevalent gynecologic cancers in the United States and account for significant mortality. Translational research into these cancers has highlighted the distinctive molecular and genomic profiles of these cancers finding that, even within a disease site, the landsc...

journal_title：Gynecologic oncology

authors： Bregar AJ,Growdon WB

更新日期：2016-02-01 00:00:00

abstract：:Cervical intraepithelial neoplasia grade 3 (CIN 3) is treated surgically. Follow-up of these patients is important to ensure successful treatment. The present study was undertaken to determine whether human papillomavirus (HPV) testing can be used to discriminate patients who will have recurrences from those who will ...

journal_title：Gynecologic oncology

authors： Chua KL,Hjerpe A

更新日期：1997-07-01 00:00:00

abstract：:Mullerian mixed tumors, as a group, are uncommon. Only 27 cases of this tumor of the fallopian tube have been reported to date. We report the 28th case of mixed mesodermal tumor, originating in the fallopian tube. A 79-year-old woman had mistaken a bloody vaginal discharge for hematuria. Various examinations showed no...

journal_title：Gynecologic oncology

authors： Kinoshita M,Asano S,Yamashita M,Matsuda T

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:Cisplatin-based combination therapy produces higher response rates and improved survival, in comparison to single-agent cisplatin in the treatment of cervical cancer. Cisplatin and paclitaxel (PT) requires a prolonged infusion and is less convenient and more toxic than the combination of carboplatin and pacli...

journal_title：Gynecologic oncology

authors： Moore KN,Herzog TJ,Lewin S,Giuntoli RL,Armstrong DK,Rocconi RP,Spannuth WA,Gold MA

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinicopathological features of ovarian Sertoli-Leydig cell tumors (SLCTs) and to explore the reasonable therapy. METHODS:A total of 40 cases of SLCTs were retrospectively reviewed. RESULTS:The incidence of SLCTs was 0.41%, with a median age of 28 years. All tumors were confined to one ovary...

journal_title：Gynecologic oncology

authors： Gui T,Cao D,Shen K,Yang J,Zhang Y,Yu Q,Wan X,Xiang Y,Xiao Y,Guo L

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:The objective of this pilot study was to determine if frailty predicts surgical complications among elderly women undergoing gynecologic oncology procedures. METHODS:A cohort of gynecologic oncology patients age ≥ 65, undergoing surgery between March and December 2011 was identified. Frailty was evaluated u...

journal_title：Gynecologic oncology

authors： Courtney-Brooks M,Tellawi AR,Scalici J,Duska LR,Jazaeri AA,Modesitt SC,Cantrell LA

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To determine whether written information and/or counseling based on the WOMAN-PRO II Program decreases symptom prevalence in women with vulvar neoplasia by a clinically relevant degree, and to explore the differences between the 2 interventions in symptom prevalence, symptom distress prevalence, and symptom e...

journal_title：Gynecologic oncology

authors： Raphaelis S,Mayer H,Ott S,Mueller MD,Steiner E,Joura E,Senn B

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Lymphadenectomy is an integral part of staging and treatment of gynecologic malignancies. We evaluated the feasibility and oncologic value of laparoscopic transperitoneal pelvic and paraaortic lymphadenectomy in correlation to complication rate and body mass index. METHODS:Between August 1994 and September 2...

journal_title：Gynecologic oncology

authors： Köhler C,Klemm P,Schau A,Possover M,Krause N,Tozzi R,Schneider A

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:Conization aims to remove pre-neoplastic lesions of the uterine cervix. Several techniques for conization have been compared, but evidence regarding the most effective therapeutic option is scant. Here, we aimed to compare the recurrence rate following laser conization and loop electrosurgical excision proced...

journal_title：Gynecologic oncology

authors： Bogani G,DI Donato V,Sopracordevole F,Ciavattini A,Ghelardi A,Lopez S,Simoncini T,Plotti F,Casarin J,Serati M,Pinelli C,Valenti G,Bergamini A,Gardella B,Dell'acqua A,Monti E,Vercellini P,Fischetti M,D'Ippolito G,Agu

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Women with persistent, recurrent, and/or metastatic cervical cancer have a poor prognosis. Even with the availability of cisplatin plus paclitaxel and bevacizumab, median overall survival (OS) is only 17.0 months, with median post-progression survival of approximately seven months. We studied the therapeutic ...

journal_title：Gynecologic oncology

authors： Huh WK,Brady WE,Fracasso PM,Dizon DS,Powell MA,Monk BJ,Leath CA 3rd,Landrum LM,Tanner EJ,Crane EK,Ueda S,McHale MT,Aghajanian C

更新日期：2020-09-01 00:00:00

abstract：:We have previously reported that simple hysterectomy is adequate therapy for microinvasive carcinoma of the cervix with less than 3 mm stromal invasion (Yajima, A., et al, Am. J. Obstet. Gynecol. 135, 685-688, 1979). However, whether it is possible to effectively treat patients with deeper stromal invasion remained in...

journal_title：Gynecologic oncology

authors： Yaegashi N,Sato S,Inoue Y,Noda K,Yajima A

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:A case of primary neuroblastoma arising from the broad ligament with excellent response to neoadjuvant bleomycin, etoposide, and cisplatin (BEP) is reported. CASE:A 48-year-old woman, G0, who presented with acute renal failure, an enlarged pelvic mass, and abdominal pain was diagnosed with adult neuroblasto...

journal_title：Gynecologic oncology

authors： Milam MR,Gabel SF,Milam RA,Liu J,Ramirez PT

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:The placental site trophoblastic tumor is a rare form of gestational trophoblastic disease. Fifteen percent of reported cases have been fatal, but predicting behavior in individual patients has been challenging. METHODS:The clinical, gross and histopathological features of 55 cases and 180 cases in the liter...

journal_title：Gynecologic oncology

authors： Baergen RN,Rutgers JL,Young RH,Osann K,Scully RE

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Although the reported incidence of carboplatin hypersensitivity is low, its occurrence is important to characterize because of potential fatal complications. The purpose of this study was to determine the current incidence of carboplatin hypersensitivity in the ovarian cancer patients compared to other oncol...

journal_title：Gynecologic oncology

authors： Navo M,Kunthur A,Badell ML,Coffer LW 2nd,Markman M,Brown J,Smith JA

更新日期：2006-11-01 00:00:00

abstract：:Retrospective review of sections of ovary from 50 patients with stage I, grade 1-3, epithelial ovarian carcinoma was performed to assess presence of cellular and nuclear atypia in noncancerous tissue adjacent to the primary tumor; ovarian tissue from 50 patients undergoing incidental oophorectomy was reviewed as well....

journal_title：Gynecologic oncology

authors： Plaxe SC,Deligdisch L,Dottino PR,Cohen CJ

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:To compare the survival experience of women with a BRCA1 mutation who enrolled in an ovarian cancer screening program with that of women who opted for preventive oophorectomy. METHODS:We followed 1964 women with a BRCA1 mutation and two ovaries intact in a prospective study. No women had ovarian cancer or ha...

journal_title：Gynecologic oncology

authors： Gronwald J,Lubinski J,Huzarski T,Cybulski C,Menkiszak J,Siołek M,Stawicka M,Sun P,Kim SJ,Kotsopoulos J,Narod SA

更新日期：2019-11-01 00:00:00

abstract：:Human ovarian carcinoma cell lines were genetically engineered to secrete the cytokine interleukin-4 (IL-4) by retroviral-mediated gene transduction. These cells were transduced with the LXSN retroviral vector containing the human IL-4 gene and the neomycin resistance selection marker. Numerous IL-4-secreting clones w...

journal_title：Gynecologic oncology

authors： Santin AD,Ioli GR,Hiserodt JC,Rose GS,Graf MR,Tocco LM,Lander JK,Eck LM,Burger RA,DiSaia PJ

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to define the clinical-therapeutical approach to endometrial cancer now being followed in some of the most important centers of reference for gynecological cancer in North America by means of a questionnaire. STUDY DESIGN:The questionnaire focused on four principal areas: (1) surgic...

journal_title：Gynecologic oncology

authors： Maggino T,Romagnolo C,Landoni F,Sartori E,Zola P,Gadducci A

更新日期：1998-03-01 00:00:00

abstract：:Endocrine and clinicopathologic findings in a 77-year-old woman with ovarian mucinous adenofibroma of borderline malignancy are reported. The preoperative levels of testosterone, androstenedione, estrone, and estradiol in her peripheral blood were 91 ng/ml, 3.78 ng/ml, 82 pg/ml, and 35 pg/ml, respectively, abnormally ...

journal_title：Gynecologic oncology

authors： Tohya T,Mizutani H,Katabuchi H,Miyazaki K,Okamura H

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:Hyperglycosylated hCG (hCG-H) is a glycosylation variant of hCG produced by cytotrophoblast cells at implantation of pregnancy and in choriocarcinoma. We investigated the biological function of hCG-H in invasion in vitro and in vivo and the use of hCG-H antibodies in blocking tumorigenesis and cancer growth i...

journal_title：Gynecologic oncology

authors： Cole LA,Dai D,Butler SA,Leslie KK,Kohorn EI

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:There are a few cases of "small cell neuroendocrine carcinoma" of the Bartholin's gland as well as Merkel cell carcinoma of the vulva reported in the gynecologic oncology literature, most with aggressive clinical behavior. Merkel cells were originally described in the epidermis with neuroendocrine properties...

journal_title：Gynecologic oncology

authors： Khoury-Collado F,Elliott KS,Lee YC,Chen PC,Abulafia O

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To examine the effect of postsurgical surveillance on survival of patients with FIGO stage I/II endometrial adenocarcinoma. METHODS:We examined the records of 354 patients who underwent primary surgical therapy for FIGO stage I/II endometrial adenocarcinoma. In patients who developed recurrent disease, we de...

journal_title：Gynecologic oncology

authors： Berchuck A,Anspach C,Evans AC,Soper JT,Rodriguez GC,Dodge R,Robboy S,Clarke-Pearson DL

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:High-risk (HR) human papillomavirus (HPV) testing is important in cervical cancer screening for triage to colposcopy. This study evaluated the clinical performance of the Cervista HPV HR and 16/18 genotyping tests for detection of HPV in cervical cytology specimens. METHODS:The tests were prospectively evalu...

journal_title：Gynecologic oncology

authors： Einstein MH,Martens MG,Garcia FA,Ferris DG,Mitchell AL,Day SP,Olson MC

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Increased Vascular Endothelial Growth Factor Receptor (VEGF) expression in endometrial cancer (EC) is associated with a poor prognosis. Preliminary clinical data reported Bevacizumab effectiveness in EC both as single agent and in combination with chemotherapy. METHODS:In a phase II trial, patients with adva...

journal_title：Gynecologic oncology

authors： Lorusso D,Ferrandina G,Colombo N,Pignata S,Pietragalla A,Sonetto C,Pisano C,Lapresa MT,Savarese A,Tagliaferri P,Lombardi D,Cinieri S,Breda E,Sabatucci I,Sabbatini R,Conte C,Cecere SC,Maltese G,Scambia G

更新日期：2019-12-01 00:00:00

abstract：:A 46-year-old woman with the complaint of hypermenorrhea underwent hysterectomy for a presumed uterine myoma. The solid tumor in the myometrium was gray in color, was 4 cm in diameter, and showed hemorrhage and necrosis. Histologically, the tumor consisted of round or polygonal cells arranged in cords and nests, and i...

journal_title：Gynecologic oncology

authors： Kuroda H,Konishi I,Nanbu K,Mandai M,Komatsu T,Yamamoto S,Yamabe H,Kida A,Mori T

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:The female genital lymphomas are an extremely rare disease accounting for less than 0.5% of gynecological cancers and for 1.5% of all NHL. Because of their low incidence there is no widely accepted consensus on its treatment. Literature data support a radiotherapy-based treatment in case of primary genital l...

journal_title：Gynecologic oncology

authors： Signorelli M,Maneo A,Cammarota S,Isimbaldi G,Garcia Parra R,Perego P,Maria Pogliani E,Mangioni C

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:To assess sexual function of vulvar cancer survivors who received extensive and less extensive treatment. To explore associations between sexual function and patient, disease, treatment, and psychological variables. METHODS:Sexual function (Female Sexual Function Index, FSFI), mental and physical well-being...

journal_title：Gynecologic oncology

authors： Hazewinkel MH,Laan ET,Sprangers MA,Fons G,Burger MP,Roovers JP

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To evaluate incidence, indications, and outcome of hysterectomy in women presenting with gestational trophoblastic disease. METHODS:A prospective observational study using a standardized protocol for registration, assessment, and treatment of gestational trophoblastic disease. A total of 5976 consecutive new...

journal_title：Gynecologic oncology

authors： Pisal N,North C,Tidy J,Hancock B

更新日期：2002-11-01 00:00:00