Merkel cell carcinoma of the Bartholin's gland.

Abstract:

BACKGROUND:There are a few cases of "small cell neuroendocrine carcinoma" of the Bartholin's gland as well as Merkel cell carcinoma of the vulva reported in the gynecologic oncology literature, most with aggressive clinical behavior. Merkel cells were originally described in the epidermis with neuroendocrine properties. Merkel cell carcinoma is different from the neuroendocrine small cell (oat cell) tumor arising in the lung and other internal organs based on morphology and immunohistochemistry. CASE:A 49-year-old female was diagnosed with a FIGO stage I Merkel cell carcinoma of the Bartholin's gland. The tumor originated from the duct and stained with endocrine markers and cytokeratin 7 and 20. She was treated with radical wide local excision and bilateral inguinal lymph node dissection followed by radiation therapy to the pelvis, perineum, vulva, and inguinal regions. Two years after the diagnosis, she is alive with no evidence of recurrent disease. CONCLUSION:This is a case of Merkel cell carcinoma of the Bartholin's gland discovered in the early stage with a survival of 2 years following diagnosis and treatment with no evidence of disease recurrence.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Khoury-Collado F,Elliott KS,Lee YC,Chen PC,Abulafia O

doi

10.1016/j.ygyno.2004.12.064

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

928-31

issue

3

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(05)00010-7

journal_volume

97

pub_type

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