Application of proteomics in ovarian cancer: which sample should be used?

abstract：OBJECTIVE:The aim of this study was to determine the prevalence and types of complementary and alternative medicine (CAM) usage by women with gynecologic cancer in an outpatient midwestern university practice. METHODS:Any patient with a gynecologic cancer seen in the outpatient clinic of the gynecologic oncology divis...

journal_title：Gynecologic oncology

authors： Swisher EM,Cohn DE,Goff BA,Parham J,Herzog TJ,Rader JS,Mutch DG

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To determine the proportion of endometrial cancer patients who can be safely prescribed community/home based unsupervised exercise. A better understanding of the physical dysfunction secondary to comorbidities among endometrial cancer patients would assist clinicians in delineating which patients to send to m...

journal_title：Gynecologic oncology

authors： Zhang X,Haggerty AF,Brown JC,Giuntoli R 2nd,Lin L,Simpkins F,Dean LT,Ko E,Morgan MA,Schmitz KH

更新日期：2015-10-01 00:00:00

abstract：:HIV infection among women is increasing in the United States. Since January 1993, cervical cancer has been considered an AIDS-defining illness. We report a rare case of squamous cell carcinoma arising in a teratoma of the uterine cervix in an HIV-infected patient. This patient was treated with a radical hysterectomy, ...

journal_title：Gynecologic oncology

authors： Bell MC,Schmidt-Grimminger DC,Connor MG,Alvarez RD

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:The expression of homologous recombination (HR) genes in high grade ovarian cancer (HGOC) samples from debulking surgeries were correlated to outcomes in patients selected for chemotherapy treatment regimens. STUDY DESIGN:RNA was extracted from 96 fresh frozen tumor samples from debulking surgeries from chem...

journal_title：Gynecologic oncology

authors： Kessous R,Octeau D,Klein K,Tonin PN,Greenwood CMT,Pelmus M,Laskov I,Kogan L,Salvador S,Lau S,Yasmeen A,Gotlieb WH

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:We describe a case of conservatively treated endometrial endometrioid (EE) adenocarcinoma which showed an aggressive clinical outcome after pregnancy. CASE:A 30-year-old woman with a well differentiated EE adenocarcinoma decided to attempt a conservative approach and underwent progestin treatment with sub...

journal_title：Gynecologic oncology

authors： Ferrandina G,Zannoni GF,Gallotta V,Foti E,Mancuso S,Scambia G

更新日期：2005-10-01 00:00:00

abstract：:Adenocarcinoma of the urethra is a rare neoplasm which is believed to arise from the periurethral ducts. Four such cases have been diagnosed at our institution during the past 25 years and their clinical courses are summarized in this report. In one patient, a disseminated coagulopathy with a predominantly fibrinolyti...

journal_title：Gynecologic oncology

authors： Taylor RN,Lacey CG,Shuman MA

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Neuroendocrine carcinomas (NECs) of the cervix comprise only 2% of all cervical cancers. Prospective data is limited and treatment guidelines rely on retrospective reviews and literature from lung NEC. The objective of this study was to report our experience in the management of this rare disease. METHODS:T...

journal_title：Gynecologic oncology

authors： McCann GA,Boutsicaris CE,Preston MM,Backes FJ,Eisenhauer EL,Fowler JM,Cohn DE,Copeland LJ,Salani R,O'Malley DM

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Advanced gynecological surgery undertaken in a specialized gynecologic oncology unit may be associated with significant perioperative morbidity. Validated risk prediction models are available for general surgical specialties but currently not for gynecological cancer surgery. OBJECTIVE:The objective of this...

journal_title：Gynecologic oncology

authors： Kondalsamy-Chennakesavan S,Bouman C,De Jong S,Sanday K,Nicklin J,Land R,Obermair A

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Borderline tumor of the ovary is an epithelial tumor with a low rate of growth and a low potential to invade or metastasize. This review will outline the most recent information regarding the molecular pathogenesis, pathology, fertility and tumor recurrence rate after conservative management of young women wi...

journal_title：Gynecologic oncology

authors： Tinelli R,Tinelli A,Tinelli FG,Cicinelli E,Malvasi A

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:Participation in clinical and basic science research is emphasized in gynecologic oncology training. We sought to identify trends in adherence to expected research practices and reasons for non-adherence among gynecologic oncology fellows. METHODS:An anonymous 31-question online survey assessing academic be...

journal_title：Gynecologic oncology

authors： Moulton LJ,Michener CM,Levinson K,Cobb L,Tseng J,Jernigan A

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to determine the incidence of endometrial cancer in young postmenopausal women presenting with vaginal bleeding. METHODS:Cross-sectional study of postmenopausal women presenting with vaginal bleeding in a gynaecological oncology centre in the United Kingdom. All women underwent...

journal_title：Gynecologic oncology

authors： Burbos N,Musonda P,Crocker SG,Morris EP,Duncan TJ,Nieto JJ

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:To compare the cost and perioperative outcomes of endometrial cancer staging when the procedure is performed by a gynecologic oncologist alone or when a general gynecologist participates in the procedure. METHODS:A retrospective analysis was performed on a series of women with clinical stage I endometrial ca...

journal_title：Gynecologic oncology

authors： Hoekstra A,Singh DK,Garb M,Arekapudi S,Rademaker A,Lurain JR

更新日期：2006-12-01 00:00:00

abstract：:In 74 patients with advanced ovarian cancer, the value of DNA flow cytometry and morphometry was evaluated and compared with histological grading and clinical outcome. By means of both DNA flow cytometry and morphometry a clear distinction was found between a favorable group of 15 patients, with a median survival of m...

journal_title：Gynecologic oncology

authors： Rodenburg CJ,Cornelisse CJ,Hermans J,Fleuren GJ

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:Hydroxysteroid-dehydrogenase-17b (HSD17b) genes control the last step in estrogen biosynthesis. The isoenzymes HSD17b2 and HSD17b4 in the uterus preferentially catalyze the conversion of estradiol, the most potent and active form of estrogen, to estrone, the inactive form of estrogen. Endometrial adenocarcino...

journal_title：Gynecologic oncology

authors： Karageorgi S,McGrath M,Lee IM,Buring J,Kraft P,De Vivo I

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to determine if three-dimensional power Doppler ultrasound improves the specificity for ovarian cancer detection as compared with two-dimensional ultrasound. METHODS:Seventy-one women with a known complex pelvic mass were referred for a preoperative ultrasound evaluation with both ...

journal_title：Gynecologic oncology

authors： Cohen LS,Escobar PF,Scharm C,Glimco B,Fishman DA

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:Intraperitoneal (IP) chemotherapy following neoadjuvant chemotherapy (NACT) and interval tumor reductive surgery (TRS) for advanced ovarian cancer is feasible, however, the impact on disease outcomes remains unclear. We compare outcomes of patients treated with IP chemotherapy versus intravenous (IV) chemoth...

journal_title：Gynecologic oncology

authors： Bixel K,Vetter M,Davidson B,Berchuck A,Cohn D,Copeland L,Fowler JM,Havrilesky L,Lee PS,O'Malley DM,Salani R,Valea F,Alvarez Secord A,Backes F

更新日期：2020-03-01 00:00:00

abstract：:The alpha-emitter 211At was bound to polymer microspheres with a diameter of 1.8 microns. The distributions in mice of intraperitoneally injected 211At microspheres, 90Y silicate colloid, and 32P chromic phosphate colloid were compared. The microspheres with 211At spread rapidly in the peritoneal cavity and remained m...

journal_title：Gynecologic oncology

authors： Vergote I,Larsen RH,De Vos L,Winderen M,Ellingsen T,Bjørgum J,Hoff P,Aas M,Tropé C,Nustad K

更新日期：1992-12-01 00:00:00

abstract：:A double complete and prolonged response of metastatic endometrial carcinoma to medroxyprogesterone is reported. A 61-year-old woman with metastatic endometrial carcinoma in lung and liver achieved a complete clinical response with medroxyprogesterone lasting for 2 years. She discontinued the therapy by herself and de...

journal_title：Gynecologic oncology

authors： Crespo C,González-Martín A,Lastra E,García-López J,Moyano A

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVES:Epidermal Growth Factor Receptor (EGF-R) up-regulation in cervical cancer cells leads to an increase in cell proliferative Insulin-like Growth Factor II (IGF-II) and Vascular Endothelial Growth Factor (VEGF) and a decrease of the anti-proliferative IGF-binding protein-3 (IGF-BP3). The objectives for this stu...

journal_title：Gynecologic oncology

authors： Mathur RS,Mathur SP

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the relationship between external parametrial dose and radiation proctitis after external irradiation and high-dose-rate intracavitary (HDR-IC) brachytherapy among patients with cervical cancer. METHODS:From May 1993 through December 1996, 191 patients with stage IB-IVA ...

journal_title：Gynecologic oncology

authors： Huang EY,Lin H,Hsu HC,Wang CJ,Chen HC,Sun LM,Hsiung CY

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this phase II study was to evaluate on an intent-to-treat basis the activity and toxicity of single-agent vinorelbine (VRL) as second-line chemotherapy of patients with platinum-resistant ovarian cancer. Platinum-resistant disease was defined as disease refractory to or relapsing within 12 mont...

journal_title：Gynecologic oncology

authors： Sørensen P,Høyer M,Jakobsen A,Malmström H,Havsteen H,Bertelsen K

更新日期：2001-04-01 00:00:00

abstract：:Endocrine and clinicopathologic findings in a 77-year-old woman with ovarian mucinous adenofibroma of borderline malignancy are reported. The preoperative levels of testosterone, androstenedione, estrone, and estradiol in her peripheral blood were 91 ng/ml, 3.78 ng/ml, 82 pg/ml, and 35 pg/ml, respectively, abnormally ...

journal_title：Gynecologic oncology

authors： Tohya T,Mizutani H,Katabuchi H,Miyazaki K,Okamura H

更新日期：1994-08-01 00:00:00

abstract：:Twelve patients with recurrent squamous cell carcinoma of the cervix restricted to the pelvis were treated with intra-arterial infusion of carboplatin. The initial carboplatin dose was 300 mg/m2, every 4 weeks, and the dose was escalated to 450 mg/m2. Myelosuppression was the dose-limiting toxicity at the 450 mg/m2 do...

journal_title：Gynecologic oncology

authors： Verma S,Prefontaine M,Bertrand M,Genest P,Dahrouge S

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:Local cervical factors may determine the outcome of human papillomavirus (HPV) infection. Nitric oxide (NO) may be one such factor, since it is produced by uterine cervical cells and it takes part in both immunological and carcinogenic reactions. We studied the association between the presence of cervical hig...

journal_title：Gynecologic oncology

authors： Rahkola P,Mikkola TS,Ylikorkala O,Vaisanen-Tommiska M

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:Endometriosis-associated ovarian carcinoma (EAOC) has recently received increasing attention due to its suggested biological behavior, distinctive from those of usual epithelial ovarian cancer. To elucidate some of the controversies on this intriguing entity, a series of patients with EAOC were compared to o...

journal_title：Gynecologic oncology

authors： Erzen M,Rakar S,Klancnik B,Syrjänen K

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To quantify the effect of race/ethnicity on risk of complete and partial molar pregnancy. METHODS:We conducted a cross-sectional study including women who were followed for complete or partial mole and those who had a live singleton birth in a teaching hospital in the northeastern United States between 2000 ...

journal_title：Gynecologic oncology

authors： Melamed A,Gockley AA,Joseph NT,Sun SY,Clapp MA,Goldstein DP,Berkowitz RS,Horowitz NS

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The aim of this retrospective multicenter study was to assess whether the pre-chemotherapy hemoglobin levels have any impact on the clinical outcome of patients with advanced epithelial ovarian cancer who received a first-line taxane/platinum-based regimen. METHODS:The study was conducted on 315 patients who...

journal_title：Gynecologic oncology

authors： Gadducci A,Sartori E,Landoni F,Zola P,Maggino T,Colombo N,Fanucchi A,Chiudinelli F,Lapresa M,Maria Ferrero A

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:The purpose of this multicenter, open label, randomized phase III study was to determine whether ixabepilone resulted in improved overall survival (OS) compared with commonly used single-agent chemotherapy (doxorubicin or paclitaxel) in women with locally advanced, recurrent, or metastatic endometrial cancer ...

journal_title：Gynecologic oncology

authors： McMeekin S,Dizon D,Barter J,Scambia G,Manzyuk L,Lisyanskaya A,Oaknin A,Ringuette S,Mukhopadhyay P,Rosenberg J,Vergote I

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Epithelioid sarcoma is a soft tissue tumor rarely found centrally and even less commonly on the vulva. Vulvar sarcoma in pregnancy is also exceedingly rare with only five cases reported to date, none of which have been an epithelioid sarcoma. CASE:We report a case of a 29-year-old woman presenting with a vu...

journal_title：Gynecologic oncology

authors： Moore RG,Steinhoff MM,Granai CO,DeMars LR

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to determine whether the length of the interval from primary surgery to commencement of chemotherapy has any direct effect on progression-free survival in ovarian cancer. METHODS:The progression-free survival of 472 patients enrolled in four trials who had all received platin...

journal_title：Gynecologic oncology

authors： Flynn PM,Paul J,Cruickshank DJ,Scottish Gynaecological Cancer Trials Group.

更新日期：2002-09-01 00:00:00