Evaluation of DNA ploidy in endometrial cancer.

abstract：BACKGROUND:A case of primary neuroblastoma arising from the broad ligament with excellent response to neoadjuvant bleomycin, etoposide, and cisplatin (BEP) is reported. CASE:A 48-year-old woman, G0, who presented with acute renal failure, an enlarged pelvic mass, and abdominal pain was diagnosed with adult neuroblasto...

journal_title：Gynecologic oncology

authors： Milam MR,Gabel SF,Milam RA,Liu J,Ramirez PT

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Uterine serous carcinoma (USC) is presumed to arise from endometrial intra-epithelial carcinoma (EIC), whereas tubo-ovarian high-grade serous carcinomas have similar precursor lesions in the Fallopian tube, i.e. serous tubal intra-epithelial carcinoma (STIC). The presence of Fallopian tube abnormalities and t...

journal_title：Gynecologic oncology

authors： Steenbeek MP,Bulten J,Snijders MPLM,Lombaers M,Hendriks J,van den Brand M,Kraayenbrink AA,Massuger LFAG,Sweegers S,de Hullu JA,Pijnenborg JMA,Küsters-Vandevelde HVN,Reijnen C

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:To compare surgical morbidity and clinical-pathologic factors for patients with endometrial cancer (EC) undergoing robotic-assisted laparoscopic hysterectomy (RALH) versus total abdominal hysterectomy (TAH) with aortic and/or pelvic lymphadenectomy (LA). METHODS:During the first 14 months of a robotics surgi...

journal_title：Gynecologic oncology

authors： DeNardis SA,Holloway RW,Bigsby GE 4th,Pikaart DP,Ahmad S,Finkler NJ

更新日期：2008-12-01 00:00:00

abstract：:A model system of exfoliated normal human cervicovaginal squamous cells, exfoliated rodent tumor cells, and acellular, viscous, mucuslike material was used to investigate cell deposition on smear preparations made with three different instruments: plastic spatulas, wooden spatulas, and brush-tipped collectors. The tot...

journal_title：Gynecologic oncology

authors： Rubio CA,Kock Y,Stormby N,Porwit A

更新日期：1990-11-01 00:00:00

abstract：:The aim of the present study was to compare the diagnostic accuracy of transvaginal sonography, color flow imaging, and serum CA 125 assay in pre- and postmenopausal women undergoing laparotomy for a clinical diagnosis of an adnexal mass. In 109 consecutive women, the morphology of the mass was evaluated with transvag...

journal_title：Gynecologic oncology

authors： Strigini FA,Gadducci A,Del Bravo B,Ferdeghini M,Genazzani AR

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of local recurrence of vulvar squamous cell carcinoma in relation to tumor- and/or precursor lesion free pathologic margins. METHODS:Consecutive patients with primary vulvar squamous cell carcinoma surgically treated in two Dutch expert centers between 2000 and 2010 were included. ...

journal_title：Gynecologic oncology

authors： Te Grootenhuis NC,Pouwer AW,de Bock GH,Hollema H,Bulten J,van der Zee AGJ,de Hullu JA,Oonk MHM

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:Participation in clinical and basic science research is emphasized in gynecologic oncology training. We sought to identify trends in adherence to expected research practices and reasons for non-adherence among gynecologic oncology fellows. METHODS:An anonymous 31-question online survey assessing academic be...

journal_title：Gynecologic oncology

authors： Moulton LJ,Michener CM,Levinson K,Cobb L,Tseng J,Jernigan A

更新日期：2017-09-01 00:00:00

abstract：:Reconstructive procedures are being performed with increasing frequency in conjunction with pelvic exenterations and other radical gynecologic surgeries. The most common reconstructive procedures include continent urinary diversion, rectosigmoid anastomosis, and vaginal reconstruction. Historically, the gracilis myocu...

journal_title：Gynecologic oncology

authors： Carlson JW,Soisson AP,Fowler JM,Carter JR,Twiggs LB,Carson LF

更新日期：1993-12-01 00:00:00

abstract：:Cancers with deficiencies in homologous recombination-mediated DNA repair (HRR) demonstrate improved clinical outcomes and increased survival. Approximately 50% of high-grade serous ovarian cancers (HGSOC) exhibit homologous recombination deficiency (HRD). HRD can be caused by germline or somatic mutations of genes in...

journal_title：Gynecologic oncology

authors： Fuh K,Mullen M,Blachut B,Stover E,Konstantinopoulos P,Liu J,Matulonis U,Khabele D,Mosammaparast N,Vindigni A

更新日期：2020-12-01 00:00:00

abstract：:A patient with Stage IIB squamous cell cancer of the cervix presented 10 days into her primary radiation therapy with neutropenic fever and diarrhea requiring hospitalization and delay in treatment. The patient's history revealed extensive use of alternative therapies including potential toxic botanicals. This case ra...

journal_title：Gynecologic oncology

authors： von Gruenigen VE,Hopkins MP

更新日期：2000-04-01 00:00:00

abstract：:To determine the effects of neoadjuvant chemotherapy (NAC) in the management of cervical carcinoma Stage IB2 (tumor diameter > 4 cm), we reviewed 52 surgically treated patients diagnosed between January 1987 and December 1993. There were 20 patients treated with preoperative neoadjuvant chemotherapy and 32 treated by ...

journal_title：Gynecologic oncology

authors： Serur E,Mathews RP,Gates J,Levine P,Maiman M,Remy JC

更新日期：1997-05-01 00:00:00

abstract：:Abnormal nuclear DNA content, as determined by flow cytometry, when combined with conventional prognostic variables such as tumor grade or stage at diagnosis, appears to identify patients who are at increased risk for recurrence of disease. The DNA content of ovarian dysgerminoma, a tumor that is homologous to testicu...

journal_title：Gynecologic oncology

authors： Palmquist MB,Webb MJ,Lieber MM,Gaffey TA,Nativ O

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:After The Cancer Genome Atlas (TCGA) findings, four novel prognostic groups may direct the management of endometrial cancer (EC): POLE-mutated/ultramutated (POLEmt), microsatellite-instable/hypermutated (MSI), copy-number-low/p53-wild-type (p53wt), and copy-number-high/p53-mutated (p53mt). However, data abou...

journal_title：Gynecologic oncology

authors： Raffone A,Travaglino A,Mascolo M,Carbone L,Guida M,Insabato L,Zullo F

更新日期：2019-11-01 00:00:00

abstract：:Aggressive tumor reduction surgery has been widely used in patients with advanced stage epithelial ovarian carcinoma before initiation of cytotoxic chemotherapy. No randomized controlled trial has been carried out to confirm the benefits of such procedures. To examine the role of cytoreductive surgery in the managemen...

journal_title：Gynecologic oncology

authors： Le T,Krepart GV,Lotocki RJ,Heywood MS

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:In this phase II study the efficacy and toxicity of an alternating chemotherapy regimen was examined in platinum-resistant relapsed epithelial ovarian cancer (EOC) patients. METHODS:Forty-five patients with platinum-refractory/resistant relapsed EOC, previously treated with carboplatin+paclitaxel+/-epirubici...

journal_title：Gynecologic oncology

authors： Pectasides D,Pectasides E,Papaxoinis G,Psyrri A,Pliarchopoulou K,Koumarianou A,Macheras A,Athanasas G,Xiros N,Economopoulos T

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classical glycolytic protein. A higher level of GAPDH mRNA was found in lung, pancreas, and prostate cancers, but in cervical carcinoma there have not been any reports about the level of GAPDH gene expression. So, we tried to investigate the GAPDH gene exp...

journal_title：Gynecologic oncology

authors： Kim JW,Kim SJ,Han SM,Paik SY,Hur SY,Kim YW,Lee JM,Namkoong SE

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:Ras gene mutations have been identified in squamous cell carcinomas of the cervix and are associated with advanced-stage tumors. The current study was designed to determine the prevalence of c-Ki-ras mutations in invasive endocervical adenocarcinomas and associations between mutations, HPV status, and known p...

journal_title：Gynecologic oncology

authors： Koulos JP,Wright TC,Mitchell MF,Silva E,Atkinson EN,Richart RM

更新日期：1993-03-01 00:00:00

abstract：:In patients with small central recurrences following radiation therapy for cervical cancer the surgeon may have to make a judgment as to when radical hysterectomy is preferable to exenteration. During the years 1968-1984 there were 21 radical hysterectomies performed at Memorial Sloan-Kettering Cancer Center for recur...

journal_title：Gynecologic oncology

authors： Rubin SC,Hoskins WJ,Lewis JL Jr

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to determine the incidence and distribution of the location of benign müllerian inclusions in pelvic and paraaortic lymph nodes. METHODS:A total of 114 patients operated on for gynecologic malignancy between 1995 and 1998 underwent surgery including systematic pelvic (n = 114) or pe...

journal_title：Gynecologic oncology

authors： Reich O,Tamussino K,Haas J,Winter R

更新日期：2000-08-01 00:00:00

abstract：:By serendipity we have had the opportunity to evaluate cis-platin-based chemotherapy in ovarian tumors of low malignant potential (LMP). Optimal (less than 1 cm residual disease) FIGO stage III ovarian carcinomas were randomly assigned to treatment with cisplatin plus cyclophosphamide with or without doxorubicin on a ...

journal_title：Gynecologic oncology

authors： Sutton GP,Bundy BN,Omura GA,Yordan EL,Beecham JB,Bonfiglio T

更新日期：1991-06-01 00:00:00

abstract：OBJECTIVES:To determine the importance of margin status and other prognostic factors associated with the recurrence and survival of patients with squamous cell vulvar carcinoma. METHODS:Data were analyzed using Kaplan-Meier methods and Cox proportional hazards regression. All slides were re-reviewed by two gynecologic...

journal_title：Gynecologic oncology

authors： Chan JK,Sugiyama V,Pham H,Gu M,Rutgers J,Osann K,Cheung MK,Berman ML,Disaia PJ

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To estimate the frequency of cervical cytologic/histologic discrepancies in a group of obstetric patients diagnosed as HIV infected by routine prenatal screening. Also, to determine if serum CD4 levels or sexually transmitted diseases (STDs) are associated with the occurrence of preinvasive cervical disease i...

journal_title：Gynecologic oncology

authors： Robinson WR,Barnes SE,Adams S,Perrin MS

更新日期：1997-06-01 00:00:00

abstract：:Human ovarian carcinomas (n = 215) were xenotransplanted into thymus-aplastic female nu/nu mice (NMRI). Growth of transplants was defined as take-off rate, growth rapidity, and feasibility of passages. In 204 cases these growth characteristics could be correlated with survival time of the individual tumor-donor patien...

journal_title：Gynecologic oncology

authors： Kleine W

更新日期：1986-09-01 00:00:00

abstract：:A study that focused on the identification of the phenotype and proliferative responses of peripheral blood and ovarian cancer-infiltrating lymphocytes in a patient with stage III ovarian cancer who had human immunodeficiency virus infection is presented. Monoclonal antibodies and flow cytometry were used to determine...

journal_title：Gynecologic oncology

authors： Guidozzi F,Reddy S,Wadee A

更新日期：1994-05-01 00:00:00

abstract：:Uterine papillary serous carcinoma (UPSC) is an uncommon but aggressive type of endometrial cancer associated with rapid progression of disease and poor prognosis. We investigated 23 cases of UPSC. p53 expression was studied in archival paraffin-embedded tissue by immunohistochemistry. Eleven tumors (47.8%) showed p53...

journal_title：Gynecologic oncology

authors： Bancher-Todesca D,Gitsch G,Williams KE,Kohlberger P,Neunteufel W,Obermair A,Heinze G,Breitenecker G,Hacker NF

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:This study was designed to analyze the results of treatment on patients with metastatic gestational trophoblastic tumor (metastatic GTT). METHOD:During 1996-2001, 38 cases with metastatic GTT were diagnosed and received treatment in Vali-e-Asr Hospital, Tehran, Iran. Data were gathered retrospectively and an...

journal_title：Gynecologic oncology

authors： Ghaemmaghami F,Behtash N,Soleimani K,Hanjani P

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:Although there have been studies that focused on the correlation between the HPV presence of pelvic lymph nodes and pathological metastasis in patients with cervical cancer, the biologic role of HPV DNA in lymph nodes still remains uncertain. We performed this study to investigate the correlation between the ...

journal_title：Gynecologic oncology

authors： Lee YS,Rhim CC,Lee HN,Lee KH,Park JS,Namkoong SE

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To describe the incidence of isolated paraaortic nodal metastasis in surgically staged endometrial cancer patients with negative pelvic lymph nodes. METHODS:Using a prospectively maintained database we identified all cases of endometrial cancer that had both pelvic and aortic nodal dissection and determined ...

journal_title：Gynecologic oncology

authors： Abu-Rustum NR,Gomez JD,Alektiar KM,Soslow RA,Hensley ML,Leitao MM Jr,Gardner GJ,Sonoda Y,Chi DS,Barakat RR

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To evaluate the long-term disease control, survival and complication rates using high-dose-rate intracavitary brachytherapy (HDRB) and external beam radiotherapy (EBRT) for patients found to have isolated vaginal recurrences from early-stage endometrial adenocarcinoma following total abdominal hysterectomy and ...

journal_title：Gynecologic oncology

authors： Pai HH,Souhami L,Clark BG,Roman T

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:Routine lymphadenectomy (LA) in early stage endometrial cancer does not improve survival. However, in the absence of lymph node metastasis, radiotherapy (RT) could be withheld and hence could result in less morbidity. Our aim was to evaluate health related quality of life (HRQL) in endometrial cancer survivo...

journal_title：Gynecologic oncology

authors： van de Poll-Franse LV,Pijnenborg JM,Boll D,Vos MC,van den Berg H,Lybeert ML,de Winter K,Kruitwagen RF

更新日期：2012-10-01 00:00:00