Differential diagnosis of adnexal masses with transvaginal sonography, color flow imaging, and serum CA 125 assay in pre- and postmenopausal women.

abstract：:Human ovarian carcinoma cell lines were genetically engineered to secrete the cytokine interleukin-4 (IL-4) by retroviral-mediated gene transduction. These cells were transduced with the LXSN retroviral vector containing the human IL-4 gene and the neomycin resistance selection marker. Numerous IL-4-secreting clones w...

journal_title：Gynecologic oncology

authors： Santin AD,Ioli GR,Hiserodt JC,Rose GS,Graf MR,Tocco LM,Lander JK,Eck LM,Burger RA,DiSaia PJ

更新日期：1995-08-01 00:00:00

abstract：:Endometrial cancer is the most common gynecologic malignancy in the Western world and is strongly associated with obesity. Despite the fact that most cases are diagnosed in early, more favorable stages, endometrial cancer incidence and mortality rates are on the rise. Morbidly obese women with endometrial cancer are m...

journal_title：Gynecologic oncology

authors： Fader AN,Arriba LN,Frasure HE,von Gruenigen VE

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:About 30% of Adult type granulosa cell tumors of the ovary (AGCTs) are diagnosed in fertile age. In stage I, conservative surgery (fertility-sparing surgery, FSS), either unilateral salpingo-oophorectomy (USO) or cystectomy are possible options. The aim of this study is to compare oncological outcomes of FSS ...

journal_title：Gynecologic oncology

authors： Bergamini A,Cormio G,Ferrandina G,Lorusso D,Giorda G,Scarfone G,Bocciolone L,Raspagliesi F,Tateo S,Cassani C,Savarese A,Breda E,De Giorgi U,Mascilini F,Candiani M,Kardhashi A,Biglia N,Perrone AM,Pignata S,Mangili G

更新日期：2019-08-01 00:00:00

abstract：UNLABELLED:Surgical staging of apparent early stage adnexal carcinoma provides indispensable information. A significant number of patients are referred to tertiary centers with inadequate staging information. We report on our experience with late results of laparoscopic restaging procedure in uncompletely managed early...

journal_title：Gynecologic oncology

authors： Leblanc E,Querleu D,Narducci F,Occelli B,Papageorgiou T,Sonoda Y

更新日期：2004-09-01 00:00:00

abstract：:The cell line HTOA was established from a well-differentiated human ovarian serous cystadenocarcinoma. This line grew well and without interruption for 51 months and was subcultivated over 130 times. The cells were epithelial in shape, and neoplastic and pleomorphic features, a jigsaw puzzle-like arrangement, desmosom...

journal_title：Gynecologic oncology

authors： Ishiwata I,Ishiwata C,Soma M,Nozawa S,Ishikawa H

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVES:Most ovarian cancer patients are diagnosed at an advanced stage (67%) and prospects for significant improvement in survival reside in early diagnosis. While expression patterns of a recently identified biomarker family, microRNA, appear to be characteristic of tumor type and developmental origin, microRNA pr...

journal_title：Gynecologic oncology

authors： Taylor DD,Gercel-Taylor C

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:The host-tumor interactions and tumor stroma may participate in the regulation of invasive behavior of tumor cells. In order to better understand the human ovarian cancer invasion we explored the possibility that normal fibroblasts could participate in the control of the spread of human ovarian cancer. RESUL...

journal_title：Gynecologic oncology

authors： Westerlund A,Hujanen E,Puistola U,Turpeenniemi-Hujanen T

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVES:Fixed-dose rate gemcitabine plus docetaxel is active as second-line therapy for metastatic uterine leiomyosarcoma. We sought to determine the activity of this regimen as first-line treatment. METHODS:Eligible women with advanced uterine leiomyosarcoma were treated with gemcitabine 900 mg/m(2) over 90 min, o...

journal_title：Gynecologic oncology

authors： Hensley ML,Blessing JA,Mannel R,Rose PG

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the safety, efficacy and impact on survival of low anterior resection and primary anastomosis at the time of en bloc resection for primary and recurrent epithelial ovarian carcinoma. METHODS:We performed a retrospective review of 46 primary and 14 recurrent epithelial ova...

journal_title：Gynecologic oncology

authors： Park JY,Seo SS,Kang S,Lee KB,Lim SY,Choi HS,Park SY

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:The first-line chemotherapy for ovarian cancer is based on a combination of platinum and taxane. To date, no reliable predictive biomarker has been recognized that is capable of identifying patients with pre-existing resistance to these agents. Here, we have established an integrated database and identified t...

journal_title：Gynecologic oncology

authors： Fekete JT,Ősz Á,Pete I,Nagy GR,Vereczkey I,Győrffy B

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Most women with ovarian cancer relapse and undergo further chemotherapy however evidence regarding the benefits of this for women with platinum-resistant disease is limited. Our objective was to determine whether there was a quality of life improvement or treatment response among women treated for platinum-re...

journal_title：Gynecologic oncology

authors： Beesley VL,Green AC,Wyld DK,O'Rourke P,Wockner LF,deFazio A,Butow PN,Price MA,Horwood KR,Clavarino AM,Australian Ovarian Cancer Study Group,Australian Ovarian Cancer Study-Quality Of Life Study Investigators,Webb PM

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:The search for effective systemic chemotherapy for endometrial cancer is ongoing. Complete responses to current drugs or regimens are infrequent, and overall survival for patients with disease not amenable to surgery or radiation therapy is poor. Dactinomycin has proven activity against a wide variety of sol...

journal_title：Gynecologic oncology

authors： Moore DH,Blessing JA,Dunton C,Buller RE,Reid GC

更新日期：1999-12-01 00:00:00

abstract：:Considerable debate centers on the optimal treatment for vulvar melanoma, as well as those clinicopathological factors influencing prognosis. We reviewed 80 patients with vulvar melanoma seen between 1949 and 1990. Primary tumors were assessed according to Chung (47 patients) and Breslow (65 patients) microstaging sys...

journal_title：Gynecologic oncology

authors： Trimble EL,Lewis JL Jr,Williams LL,Curtin JP,Chapman D,Woodruff JM,Rubin SC,Hoskins WJ

更新日期：1992-06-01 00:00:00

abstract：OBJECTIVE:To examine tumor characteristics and survival outcome of women with uterine carcinosarcoma who had a history of tamoxifen use. METHODS:This is a multicenter retrospective study examining stage I-IV uterine carcinosarcoma cases based on history of tamoxifen use. Patient demographics, tumor characteristics, tr...

journal_title：Gynecologic oncology

authors： Matsuo K,Ross MS,Bush SH,Yunokawa M,Blake EA,Takano T,Ueda Y,Baba T,Satoh S,Shida M,Ikeda Y,Adachi S,Yokoyama T,Takekuma M,Takeuchi S,Nishimura M,Iwasaki K,Yanai S,Klobocista MM,Johnson MS,Machida H,Hasegawa K,

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:The objectives of this study are to analyze the clinicopathologic features of villoglandular papillary adenocarcinoma (VGPA) of the uterine cervix and to discuss the management thereof. We examined 13 patients with VGPA. METHODS:Clinical profiles, including patient age, clinical stage, surgical procedure, a...

journal_title：Gynecologic oncology

authors： Utsugi K,Shimizu Y,Akiyama F,Umezawa S,Hasumi K

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To compare the cost and perioperative outcomes of endometrial cancer staging when the procedure is performed by a gynecologic oncologist alone or when a general gynecologist participates in the procedure. METHODS:A retrospective analysis was performed on a series of women with clinical stage I endometrial ca...

journal_title：Gynecologic oncology

authors： Hoekstra A,Singh DK,Garb M,Arekapudi S,Rademaker A,Lurain JR

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:Intraperitoneal (IP) chemotherapy following neoadjuvant chemotherapy (NACT) and interval tumor reductive surgery (TRS) for advanced ovarian cancer is feasible, however, the impact on disease outcomes remains unclear. We compare outcomes of patients treated with IP chemotherapy versus intravenous (IV) chemoth...

journal_title：Gynecologic oncology

authors： Bixel K,Vetter M,Davidson B,Berchuck A,Cohn D,Copeland L,Fowler JM,Havrilesky L,Lee PS,O'Malley DM,Salani R,Valea F,Alvarez Secord A,Backes F

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To profile long non-coding RNA (lncRNA) expression at the various anatomic sites of high-grades serous carcinoma (HGSC) and in effusion-derived exosomes. METHODS:LncRNA profiling was performed on 60 HGSC specimens, including 10 ovarian tumors, 10 solid metastases and 10 malignant effusions, as well as exosom...

journal_title：Gynecologic oncology

authors： Filippov-Levy N,Cohen-Schussheim H,Tropé CG,Hetland Falkenthal TE,Smith Y,Davidson B,Reich R

更新日期：2018-03-01 00:00:00

abstract：:From 1971 through 1981, 81 women received 4350 to 5075 rad to the periaortic lymph nodes as part of their primary management for carcinoma of the uterine cervix. While two patients developed chronic small bowel damage, only one required surgical intervention. Five-year disease-free survival was 40%. Approximately one-...

journal_title：Gynecologic oncology

authors： Potish R,Adcock L,Jones T Jr,Levitt S,Prem K,Savage J,Twiggs L

更新日期：1983-02-01 00:00:00

abstract：:The Swedish Tumor Registries are population based. Three hundred eighty-four patients with epithelial ovarian cancer registered in the Tumor Registry of the Southeast Health Care Region during the years 1984 to 1987 were reviewed; 332 patients were eligible for survival analysis. The protocol treatment during this per...

journal_title：Gynecologic oncology

authors： Högberg T,Carstensen J,Simonsen E

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Human papillomavirus type 16 variants have been described and may have different biologic activities: this has implications for the design of HPV vaccines. OBJECTIVES:The aim of this study was to see if the HPV16 variant E-G 131 can be detected in women with preinvasive disease and to consider the histologi...

journal_title：Gynecologic oncology

authors： Etherington IJ,Ellis JR,Luesley DM,Moffitt DD,Young LS

更新日期：1999-01-01 00:00:00

abstract：:Leiomyosarcoma, a rare malignancy of smooth muscle, may arise from the retroperitoneum and present with the same vague symptoms as a malignancy of the pelvic organs. The purpose of this paper is to review eight cases of retroperitoneal leiomyosarcoma and to illustrate the presenting symptoms, prognostic indicators, an...

journal_title：Gynecologic oncology

authors： Todd CS,Michael H,Sutton G

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Overexpression of the tyrosine kinase receptor erbB-2 is important in the pathogenesis of a variety of neoplasms including ovarian cancer. As a strategy to selectively eradicate erbB-2-overexpressing tumor cells, an anti-erbB-2 single-chain immunoglobin (sFv) gene was constructed to direct expression of intra...

journal_title：Gynecologic oncology

authors： Deshane J,Cabrera G,Grim JE,Siegal GP,Pike J,Alvarez RD,Curiel DT

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVES:Endometrioid adenocarcinoma of the endometrium (EEC) is the most common histologic type of endometrial cancer, with stage being the most critical prognostic factor. Cervical involvement (CI), divided into IIA (epithelial involvement) and IIB (stromal invasion), is overall associated with decreased survival (...

journal_title：Gynecologic oncology

authors： Orezzoli JP,Sioletic S,Olawaiye A,Oliva E,del Carmen MG

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether DNA ploidy correlates with the four molecular subgroups of endometrial carcinoma (EC) as determined using ProMisE (Proactive Molecular Risk Classifier for Endometrial Cancer). METHODS:90 cases of EC previously characterized by clinicopathological parameters, outcomes, and ProMi...

journal_title：Gynecologic oncology

authors： Proctor L,Pradhan M,Leung S,Cheng A,Lee CH,Soslow RA,Gilks CB,Talhouk A,McAlpine JM,Danielsen HE,Hoang LN

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to survey the brachytherapy practice for cervical cancer in the United States. METHODS:The Clinical Research Committee of the American Brachytherapy Society (ABS) performed a retrospective survey of individual physicians of the ABS and American Society of Therapeutic Radiologists ...

journal_title：Gynecologic oncology

authors： Nag S,Orton C,Young D,Erickson B

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:Advanced ovarian cancer (OC) commonly spreads to cardiophrenic lymph nodes (CPLNs), and is often visible on preoperative imaging. We investigated the prognostic significance of abnormal CPLNs in OC detected by preoperative CT scans using three different definitions. METHODS:Patients undergoing primary debulk...

journal_title：Gynecologic oncology

authors： Mert I,Kumar A,Sheedy SP,Weaver AL,McGree ME,Kim B,Cliby WA

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:It is well established that many human tumors can express somatostatin receptors. This is the molecular basis for the application of long-acting somatostatin analogues for therapeutic and diagnostic purposes. However, there are discrepancies in earlier studies regarding the prevalence of somatostatin receptor...

journal_title：Gynecologic oncology

authors： Schulz S,Schmitt J,Quednow C,Roessner A,Weise W

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:We demonstrate the feasibility of implementing a referral and management system for cryotherapy-ineligible women in a "screen-and-treat" cervical cancer prevention program targeting HIV-infected women in Zambia. METHODS:We established criteria for patient referral, developed a training program for loop elect...

journal_title：Gynecologic oncology

authors： Pfaendler KS,Mwanahamuntu MH,Sahasrabuddhe VV,Mudenda V,Stringer JS,Parham GP

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:There are currently limited published data available on the safety and feasibility of the prolonged administration of paclitaxel. The goal of this study was to review the cumulative toxicity associated with the continuous long-term administration of this agent to women with gynecologic cancers. METHODS:Eleve...

journal_title：Gynecologic oncology

authors： Rohl J,Kushner D,Markman M

更新日期：2001-05-01 00:00:00