Psoriatic Nail Changes Are Associated With Clinical Outcomes in Psoriatic Arthritis.


BACKGROUND:Nail changes are common in psoriatic arthritis (PsA), with varying relationships existing between skin, nail, and joint disease. OBJECTIVE:To further characterize relationships between nail changes, psoriasis, and joint involvement in PsA patients. METHODS:One hundred eighty-eight PsA patients had skin, fingernail, and rheumatological assessments completed. Hand and fingernail photographs were taken and reviewed by a dermatologist. RESULTS:Higher swollen joint counts were associated with distal interphalangeal (DIP)/periungual psoriasis (P=.001), more splinter hemorrhages (P=.006), and any nail bed change (P=.03). Higher tender joint counts were associated with rough onychorrhexis (P<.001), DIP/periungual psoriasis (P=.03), red lunula (P=.001), nail crumbling (P=.046), any nail matrix (P=.03), and nail bed change (P=.03). Joint involvement was associated with same-digit nail changes; strongest association was swollen or tender DIP with subungual hyperkeratosis, odds ratio=26.6 (95% CI, 5.1-139.1). CONCLUSION:The DIP/periungual psoriasis and specific nail changes were associated with higher joint counts and certain nail changes with same-digit joint involvement.


J Cutan Med Surg


Sandre MK,Rohekar S,Guenther L




Has Abstract


2015-07-01 00:00:00














  • Non-melanoma Skin Cancer in Canada Chapter 5: Management of Squamous Cell Carcinoma.

    abstract:BACKGROUND:Squamous cell carcinoma (SCC) is the second-most common form of non-melanoma skin cancer (NMSC). OBJECTIVE:To provide guidance to Canadian health care practitioners regarding management of SCCs. METHODS:Literature searches and development of graded recommendations were carried out as discussed in the accom...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,实务指引


    authors: Sapijaszko M,Zloty D,Bourcier M,Poulin Y,Janiszewski P,Ashkenas J,Canadian Non-melanoma Skin Cancer Guidelines Committee.

    更新日期:2015-05-01 00:00:00

  • Favre-Racouchot syndrome in a 39-year old female following radiation therapy.

    abstract:BACKGROUND:Favre-Racouchot syndrome is a cutaneous disease characterized by nodules, cysts, and comedones that typically develops on sun-exposed areas of the face. This syndrome most commonly affects white males between the ages of 40 and 60 years and is frequently associated with chronic sun exposure and, more recentl...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Sutherland AE,Green PJ

    更新日期:2014-01-01 00:00:00

  • Usability, Satisfaction, and Usefulness of an Illustrated Eczema Action Plan.

    abstract:BACKGROUND:An eczema action plan (EAP) is an individualized tool to help caregivers and patients self-manage eczema. While novel illustrated EAPs have been developed and validated, there is limited literature examining the value of EAPs from patient and caregiver perspectives. OBJECTIVES:The objective of this study wa...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Shelley AJ,McDonald KA,McEvoy A,Sauder M,Kanigsberg N,Zemek R,Vaillancourt R,Pouliot A,Ramien ML

    更新日期:2018-11-01 00:00:00

  • Severe Acute Respiratory Syndrome Coronavirus 2 and the Use of Biologics in Patients With Psoriasis [Formula: see text].

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Ladda M,Lynde C,Fleming P

    更新日期:2020-11-01 00:00:00

  • Short-Term Evaluation of the Real-World Efficacy and Safety of Dupilumab for the Treatment of Moderate-to-Severe Atopic Dermatitis: A Canadian Multicenter Retrospective Cohort Study [Formula: see text].

    abstract:BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


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    更新日期:2020-09-01 00:00:00

  • Multiple symmetric lipomatosis.

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Gomes da Silva R,Detoffol Bragança R,Ribeiro Costa C,Torres de Melo L,Weiss Telles R,Costa Silva L

    更新日期:2011-07-01 00:00:00

  • Purse-string suture for round and oval defects: a useful technique in dermatologic surgery.

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Zhu JW,Wu XJ,Lu ZF,Cai SQ,Zheng M

    更新日期:2012-01-01 00:00:00

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Smith KJ,Skelton H

    更新日期:2002-05-01 00:00:00

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    abstract:BACKGROUND:Calciphylaxis is a rare syndrome of vascular calcification with subsequent cutaneous and tissue necrosis. It usually manifests as a complication of end-stage renal failure, affecting 1 to 4% of long-term dialysis patients. Very exceptionally, it can occur without chronic renal failure. OBJECTIVE:The goal of...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Stanciu M,Gagné-Henley A,Thérien G

    更新日期:2011-09-01 00:00:00

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    abstract:BACKGROUND:A new treatment for actinic keratoses, ingenol mebutate, was recently approved by the US Food and Drug Administration. OBJECTIVE:To review the mechanisms of action, efficacy and safety data, and practical recommendations for ingenol mebutate. METHODS:The PubMed and databases were searche...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Gupta AK,Paquet M

    更新日期:2013-05-01 00:00:00

  • Exacerbation of psoriasis under efalizumab therapy.

    abstract:BACKGROUND:Efalizumab is a recombinant humanized IgG1-kappa isotype monoclonal antibody that binds to CD11a, inhibiting T-cell activation. It has been approved for the treatment of moderate to severe plaque psoriasis. Efalizumab has been associated with the development of skin eruptions during the administration period...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Rallis E,Verros C,Karanikola E,Valaskatzi A,Papaconstantis M

    更新日期:2009-03-01 00:00:00

  • Successful treatment of refractory aquagenic pruritus with naltrexone.

    abstract:BACKGROUND:Aquagenic pruritus is an intense prickling sensation that develops in affected individuals immediately after contact with water at any temperature. It is most commonly associated with polycythemia rubra vera. Common but often ineffective treatments include anticholinergics and antihistamines. Other moderatel...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Ingber S,Cohen PD

    更新日期:2005-10-01 00:00:00

  • Rationale and Argument for Subunit Mohs Excision in Nasal Reconstruction.

    abstract:BACKGROUND:Optimal aesthetic results are achieved when nasal defects after Mohs micrographic surgery (MMS) are reconstructed as entire nasal subunits. OBJECTIVE:To illustrate the importance of reconstructing the nose in entire subunits and explore the possibilities of expanding the principles of subunit reconstruction...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Jergensen ZR,Pezeshk RA,Thornton JF

    更新日期:2016-07-01 00:00:00

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    abstract:BACKGROUND:Cutaneous reactions to drugs are among the most common clinical manifestations of adverse drug events (ADEs); however, data on outpatient cutaneous adverse drug events (CADEs) are limited. PURPOSE:To provide national estimates of outpatient CADEs and determine their most frequent causes. METHODS:Outpatient...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Koelblinger P,Dabade TS,Gustafson CJ,Davis SA,Yentzer BA,Kiracofe EA,Feldman SR

    更新日期:2013-07-01 00:00:00

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    abstract:BACKGROUND:Although betamethasone valerate (BMV) foam, 0.12% (Luxiq, Connectics Corporation, Palo Alto, CA) is approved by the Food and Drug Administration for the treatment of corticosteroid-responsive scalp dermatoses, no data are available for its use on nonscalp psoriasis. OBJECTIVE:We evaluated the safety and eff...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Stein LF,Sherr A,Solodkina G,Gottlieb AB,Chaudhari U

    更新日期:2001-07-01 00:00:00

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Sladden C,Kirchhof MG,Crawford RI

    更新日期:2014-11-01 00:00:00

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Atzori L,Pinna AL,Pau M,Aste N,Zucca M,Ferreli C

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Kittridge A,Routhouska SB,Korman NJ

    更新日期:2011-01-01 00:00:00

  • The Real-Life Effectiveness and Safety of Omalizumab Updosing in Patients With Chronic Spontaneous Urticaria.

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Salman A,Comert E

    更新日期:2019-09-01 00:00:00

  • Cellulitis Secondary to Liquid Nitrogen Cryotherapy: Case Report and Literature Review.

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 传,历史文章,杂志文章


    authors: Jackson R

    更新日期:1999-01-01 00:00:00

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    abstract:BACKGROUND:Several clinical trials have established the benefit of using a topical corticosteroid in conjunction with tazarotene gel in the treatment of plaque psoriasis. However, there is little information comparing the relative benefits of different corticosteroids, or different formulations of corticosteroids, when...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Green L,Sadoff W

    更新日期:2002-03-01 00:00:00

  • Malignant melanoma in a patient with oculocutaneous albinism.

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Streutker CJ,McCready D,Jimbow K,From L

    更新日期:2000-07-01 00:00:00

  • The remittive effects of alefacept.

    abstract::The duration of response to treatment with alefacept has been assessed in patients with moderate to severe chronic plaque psoriasis who responded to alefacept therapy in phase 2 and phase 3 clinical studies. In a phase 2 trial, duration of response was based on time to retreatment with alefacept. In two phase 3 studie...

    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Krueger GG

    更新日期:2004-12-01 00:00:00

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: English JC 3rd,Derdeyn AS,Wilson WM,Patterson JW

    更新日期:2003-07-01 00:00:00

  • Elastosis perforans serpignosa: treatment with liquid nitrogen cryotherapy and review of the literature.

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Humphrey S,Hemmati I,Randhawa R,Crawford RI,Hong CH

    更新日期:2010-01-01 00:00:00

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    pub_type: 杂志文章


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    更新日期:2012-03-01 00:00:00

  • Schnitzler Syndrome Without a Monoclonal Gammopathy: A Case Report.

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Urbanski M,Holfeld K,Milne A,Abbas M

    更新日期:2016-11-01 00:00:00

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章,评审


    authors: Falanga V

    更新日期:1998-12-01 00:00:00

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    journal_title:Journal of cutaneous medicine and surgery

    pub_type: 杂志文章


    authors: Al-Shobaili HA

    更新日期:2014-10-01 00:00:00