Successful treatment of refractory aquagenic pruritus with naltrexone.

abstract：:The duration of response to treatment with alefacept has been assessed in patients with moderate to severe chronic plaque psoriasis who responded to alefacept therapy in phase 2 and phase 3 clinical studies. In a phase 2 trial, duration of response was based on time to retreatment with alefacept. In two phase 3 studie...

journal_title：Journal of cutaneous medicine and surgery

authors： Krueger GG

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Apligraf is a bioengineered skin product composed of neonatal fibroblasts and keratinocytes. The FDA has approved Apligraf for the treatment of chronic venous ulcers and diabetic ulcers. OBJECTIVE:We review the development of bioengineered skin, examine the cellular activities of various growth factors that...

journal_title：Journal of cutaneous medicine and surgery

authors： Shen JT,Falanga V

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Optimal aesthetic results are achieved when nasal defects after Mohs micrographic surgery (MMS) are reconstructed as entire nasal subunits. OBJECTIVE:To illustrate the importance of reconstructing the nose in entire subunits and explore the possibilities of expanding the principles of subunit reconstruction...

journal_title：Journal of cutaneous medicine and surgery

authors： Jergensen ZR,Pezeshk RA,Thornton JF

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Keratoelastoidosis marginalis is a rare disease that is a variant of solar elastosis. Long-term ultraviolet radiation exposure and chronic trauma secondary to manual labor are considered to be inciting factors. OBJECTIVE:To outline the clinical and histological features of this disorder. METHODS:We report ...

journal_title：Journal of cutaneous medicine and surgery

authors： Mengesha YM,Kayal JD,Swerlick RA

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Squamous cell carcinoma (SCC) is the second-most common form of non-melanoma skin cancer (NMSC). OBJECTIVE:To provide guidance to Canadian health care practitioners regarding management of SCCs. METHODS:Literature searches and development of graded recommendations were carried out as discussed in the accom...

journal_title：Journal of cutaneous medicine and surgery

authors： Sapijaszko M,Zloty D,Bourcier M,Poulin Y,Janiszewski P,Ashkenas J,Canadian Non-melanoma Skin Cancer Guidelines Committee.

更新日期：2015-05-01 00:00:00

abstract：:We report a case of an 17-year-old male with a drug reaction in the spectrum of Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), triggered by carbamazepine, who was succesfully treated with the combination of dexamethasone, cyclosporine, and etanercept. This triple therapy halted and prevented skin epi...

journal_title：Journal of cutaneous medicine and surgery

authors： Coulombe J,Belzile E,Duhamel A,Rault P,Buteau C,DeBruycker JJ,Bussières JF

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Genital herpes is a very common sexually transmitted disease. Safe and effective therapies are needed for patients with frequent recurrences. OBJECTIVE:The aim of our study was to determine the efficacy and safety of famciclovir for suppression of herpes simplex virus (HSV) infection in patients with histor...

journal_title：Journal of cutaneous medicine and surgery

authors： Tyring SK,Diaz-Mitoma F,Shafran SD,Locke LA,Sacks SL,Young CL

更新日期：2003-11-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichen...

journal_title：Journal of cutaneous medicine and surgery

authors： Thomas MG,Betsy A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Darier's disease is an autosomal dominant genodermatosis typified by hyperkeratotic papules and plaques in a predominately seborrheic distribution. The vesiculo-bullous variant of Darier's disease is rare. Several previously reported cases have demonstrated clinical and microscopic features resembling famili...

journal_title：Journal of cutaneous medicine and surgery

authors： Klimas N,West C,Tarbox M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma is a rare, aggressive, malignant cutaneous tumor of the elderly or immunosuppressed individuals that usually appears on sun-exposed areas of the body. Its pathogenesis is still debated, and, currently, no standardized treatment exists. OBJECTIVE:To provide a current updated review of t...

journal_title：Journal of cutaneous medicine and surgery

authors： Zampetti A,Feliciani C,Massi G,Tulli A

更新日期：2010-03-01 00:00:00

abstract：:Psoriasis is a T-cell mediated skin disease that affects approximately 2% of the population worldwide. Despite the prevalence of the disease and long-standing efforts to develop strategies to treat it, there is a need for safe and effective therapies to treat psoriasis, particularly the more severe forms. Biological a...

journal_title：Journal of cutaneous medicine and surgery

authors： Langley RG,Ho V,Lynde C,Papp KA,Poulin Y,Shear N,Toole J,Zip C

更新日期：2006-01-01 00:00:00

abstract：:Leprosy reactions are acute inflammatory episodes that occur in the setting of Mycobacterium leprae infection. Precipitants of reactions can be pharmacologic and nonpharmacologic. Both type 1 and type 2 reactions typically occur before and during leprosy treatment but may also occur after treatment has been completed....

journal_title：Journal of cutaneous medicine and surgery

authors： Wu J,Boggild AK

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Lymphangiosarcoma is a rare, aggressive malignancy that originates from the endothelial cells lining lymphatic vessels and carries an extremely poor prognosis. Its clinical and histologic features are often indistinguishable from angiosarcoma. OBJECTIVE:We sought to better characterize the clinical and hist...

journal_title：Journal of cutaneous medicine and surgery

authors： Mamelak AJ,Collie MR,Kroll R,Hanson ML,Harris HM

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Erosive lichen planus is a painful and disabling disease that is frequently resistant to topical and systemic therapies. Current therapies are considered palliative rather than curative as many patients relapse after discontinuing treatment. An association has been reported between some cases of oral lichen ...

journal_title：Journal of cutaneous medicine and surgery

authors： Donovan JC,Hayes RC,Burgess K,Leong IT,Rosen CF

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The development of knowledge concerning the role of sun exposure in causing skin cancer has been a gradual one. OBJECTIVE:This article reviews the article by Urbach who used manikin coated with an ultraviolet dosimeter to see exactly where on the head and neck the exposure was greatest. CONCLUSION:Urbach s...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：1999-01-01 00:00:00

abstract：:The Maintenance of Certification (MOC) Program administered by the Royal College of Physicians and Surgeons applies to all Fellows of the Royal College including dermatologists. It is mandatory for those who wish to maintain their fellowship in the Royal College and can be critical for maintaining licensure requiremen...

journal_title：Journal of cutaneous medicine and surgery

authors： Rich P

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Local skin reactions are common during imiquimod treatment of actinic keratosis (AK). Cyclical application of imiquimod may improve tolerability while maintaining efficacy. OBJECTIVE:To assess the tolerability of imiquimod and clearance rate of AK lesions after imiquimod application. METHODS:Imiquimod 5% c...

journal_title：Journal of cutaneous medicine and surgery

authors： Rivers JK,Rosoph L,Provost N,Bissonnette R

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Topical minoxidil solution (TMS) is widely used for androgenetic alopecia (AGA), and this is the first report of a large safety trial. OBJECTIVES:The aim of the study was to evaluate the safety profile of TMS by comparing hospitalization and death rates among subjects using TMS with controls. Cardiovascular...

journal_title：Journal of cutaneous medicine and surgery

authors： Shapiro J

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:PASI is an inadequate outcome measure for the assessment of psoriasis treatments. No currently used endpoints provide a benefit: risk assessment of treatment taking into consideration all available efficacy and safety data. OBJECTIVE:To propose a new outcome measure called "safe psoriasis control" (SPC), wh...

journal_title：Journal of cutaneous medicine and surgery

authors： Papp KA,Henninger E

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Several clinical trials have established the benefit of using a topical corticosteroid in conjunction with tazarotene gel in the treatment of plaque psoriasis. However, there is little information comparing the relative benefits of different corticosteroids, or different formulations of corticosteroids, when...

journal_title：Journal of cutaneous medicine and surgery

authors： Green L,Sadoff W

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Sun-induced malignancies (basal cell and squamous cell carcinomas) are common in oculocutaneous albinism, however, the incidence of malignant melanoma is a topic of controversy. OBJECTIVE:We have reviewed the literature and report a case of a woman with oculocutaneous albinism with an amelanotic melanoma of...

journal_title：Journal of cutaneous medicine and surgery

authors： Streutker CJ,McCready D,Jimbow K,From L

更新日期：2000-07-01 00:00:00

abstract：:Larva currens is the cutaneous manifestation of human infection with the geotropic helminth Strongyloides stercoralis. Strongyloidiasis is a lifelong infection unless treated. A high index of suspicion is needed to prevent chronic symptoms of strongyloidiasis (eg, larva currens, eosinophilia, abdominal discomfort) and...

journal_title：Journal of cutaneous medicine and surgery

authors： Bailey KE,Danylo A,Boggild AK

更新日期：2015-07-01 00:00:00

abstract：:Sarcoidosis is a multisystem inflammatory condition of unknown etiology. Variability in the cutaneous features of sarcoidosis is profound, and its protean manifestations affirm the condition's designation as one of dermatology's "great mimics." Cutaneous phenotypes of sarcoidosis include but are by no means limited to...

journal_title：Journal of cutaneous medicine and surgery

authors： Hudson AD,Klimas NK,Stetson CL

更新日期：2018-07-01 00:00:00

abstract：:We present the extraordinary case of a 72-year-old man with a history of primary cutaneous peripheral T-cell lymphoma not otherwise specified (pcPTCL-NOS) previously controlled with topical agents who developed tumours in a sporotrichoid pattern. Culture of the tumours was negative, and histopathology showed findings ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lewis DJ,Vin H,Hinojosa T,Tetzlaff MT,Dabaja BS,Duvic M

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The classification of many pigmented lesions is not well defined, and an association with melanoma has not been established. OBJECTIVE:To better define the spectrum of pigmented lesions (excluding common and dysplastic nevi) and explore links to melanoma. METHODS:Retrospective review of patients with total...

journal_title：Journal of cutaneous medicine and surgery

authors： Menon K,Dusza SW,Marghoob AA,Halpern AC,Nehal KS

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Crohn disease of the vulva is a rare disease that is difficult to diagnose. There are limited reports describing treatment of this condition. OBJECTIVE:To describe the diagnosis and treatment of a 16-year-old girl with Crohn disease of the vulva, without onset of intestinal symptoms. METHODS:Crohn disease ...

journal_title：Journal of cutaneous medicine and surgery

authors： Zhang AJ,Zhan SH,Chang H,Gao YQ,Li YQ

更新日期：2015-01-01 00:00:00

abstract：:A renaissance is taking place in the field of wound healing. Interest in wounds has probably never been so great, and a number of key therapeutic advances in the last 2 or 3 years are only an indication of more progress to come. In large part, we are benefitting from decades of basic research that has provided the kno...

journal_title：Journal of cutaneous medicine and surgery

authors： Falanga V

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Round and oval skin wounds, like facial pigmented nevi after excision, are traditionally sutured linearly for closure, leaving significant scars, which greatly influences their appearance. OBJECTIVE:This article provides an overview of our experience using intradermal purse-string suture for round and oval ...

journal_title：Journal of cutaneous medicine and surgery

authors： Zhu JW,Wu XJ,Lu ZF,Cai SQ,Zheng M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Any scientific discipline needs a sharply defined set of words for exact and reproducible communication. Surprisingly this has never been a strong point in dermatological science, especially as regards the living gross pathology of skin disease. OBJECTIVE:This article briefly reviews the four editions of a ...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：2001-11-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is ref...

journal_title：Journal of cutaneous medicine and surgery

authors： Ladha MA,Haber RM

更新日期：2018-09-01 00:00:00